This list contains a list of EC numbers for the fourth group, EC 4, lyases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology

International Union of Biochemistry and Molecular Biology

The International Union of Biochemistry and Molecular Biology is an international non-governmental organisation concerned with biochemistry and molecular biology...

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EC 4.1.1: Carboxy-Lyases

Carboxy-lyases

Carboxy-lyases, also known as decarboxylases, are carbon–carbon lyases that add or remove a carboxyl group from organic compounds.These enzymes catalyze the decarboxylation of amino acids, beta-keto acids and alpha-keto acids....

: pyruvate decarboxylase

Pyruvate decarboxylase

Not to be confused with pyruvate dehydrogenase, the enzyme which catalyses the link reaction.Pyruvate decarboxylase is a homotetrameric enzyme that catalyses the decarboxylation of pyruvic acid to acetaldehyde and carbon dioxide in the cytoplasm. It is also called 2-oxo-acid carboxylase,...

: oxalate decarboxylase

Oxalate decarboxylase

In enzymology, an oxalate decarboxylase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are oxalate and H+, whereas its two products are formate and CO2....

: oxaloacetate decarboxylase

Oxaloacetate decarboxylase

Oxaloacetate decarboxylase is a carboxy-lyase involved in the conversion of oxaloacetate into pyruvate.It is categorized under ....

: acetoacetate decarboxylase

Acetoacetate decarboxylase

- Activity in bacteria :In certain bacteria, acetoacetate decarboxylase is involved in solventogenesis, a process by which the butyric and acetic acid products of classical sugar fermentation are oxidized into acetone and butanol...

: acetolactate decarboxylase

Acetolactate decarboxylase

In enzymology, an acetolactate decarboxylase is an enzyme that catalyzes the chemical reaction-2-hydroxy-2-methyl-3-oxobutanoate \rightleftharpoons -2-acetoin + CO2...

: aconitate decarboxylase

Aconitate decarboxylase

In enzymology, an aconitate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, cis-aconitate, and two products, itaconate and CO2....

: benzoylformate decarboxylase

Benzoylformate decarboxylase

In enzymology, a benzoylformate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, benzoylformate, and two products, benzaldehyde and CO2....

: oxalyl-CoA decarboxylase

Oxalyl-CoA decarboxylase

In enzymology, an oxalyl-CoA decarboxylase is an enzyme primarily produced by the gastrointestinal bacterium Oxalobacter formigenes that catalyzes the chemical reaction...

: malonyl-CoA decarboxylase

Malonyl-CoA decarboxylase

Malonyl-CoA decarboxylase is an enzyme associated with Malonyl-CoA decarboxylase deficiency.It catalyzes the conversion of malonyl-CoA into acetyl-CoA and carbon dioxide.To some degree, it reverses the action of Acetyl-CoA carboxylase....

: deleted, included in EC 4.1.1.12: aspartate 1-decarboxylase

Aspartate 1-decarboxylase

In enzymology, an aspartate 1-decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-aspartate, and two products, beta-alanine and CO2....

: aspartate 4-decarboxylase

Aspartate 4-decarboxylase

In enzymology, an aspartate 4-decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-aspartate, and two products, L-alanine and CO2....

: deleted: valine decarboxylase

Valine decarboxylase

In enzymology, a valine decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-valine, and two products, 2-methylpropanamine and CO2....

: glutamate decarboxylase

Glutamate decarboxylase

Glutamate decarboxylase or glutamic acid decarboxylase is an enzyme that catalyzes the decarboxylation of glutamate to GABA and CO2. GAD uses PLP as a cofactor. The reaction proceeds as follows:...

: hydroxyglutamate decarboxylase

Hydroxyglutamate decarboxylase

In enzymology, a hydroxyglutamate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3-hydroxy-L-glutamate, and two products, 4-amino-3-hydroxybutanoate and CO2....

: ornithine decarboxylase

Ornithine decarboxylase

The enzyme ornithine decarboxylase catalyzes the decarboxylation of ornithine to form putrescine. This reaction is the committed step in polyamine synthesis. In humans, this protein has 461 amino acids and forms a homodimer....

: lysine decarboxylase

Lysine decarboxylase

Lysine decarboxylase is an enzyme that converts lysine to cadaverine....

: arginine decarboxylase

Arginine decarboxylase

In enzymology, an arginine decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-arginine, and two products, agmatine and CO2....

: diaminopimelate decarboxylase

Diaminopimelate decarboxylase

In enzymology, a diaminopimelate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, meso-2,6-diaminoheptanedioate, and two products, L-lysine and CO2....

: phosphoribosylaminoimidazole carboxylase

Phosphoribosylaminoimidazole carboxylase

Phosphoribosylaminoimidazole carboxylase is an enzyme involved in nucleotide biosynthesis and in particular in purine biosynthesis...

: histidine decarboxylase

Histidine decarboxylase

Histidine decarboxylase is the enzyme that catalyzes the reaction that produces histamine from histidine with the help of vitamin B6 as follows:C6H9N3O2 → C5H9N3 + CO2...

: orotidine-5'-phosphate decarboxylase: aminobenzoate decarboxylase

Aminobenzoate decarboxylase

In enzymology, an aminobenzoate decarboxylase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 4-aminobenzoate and 2-aminobenzoate, whereas its two products are aniline and CO2....

: tyrosine decarboxylase

Tyrosine decarboxylase

In enzymology, a tyrosine decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-tyrosine, and two products, tyramine and carbon dioxide....

: deleted, included in EC 4.1.1.28: deleted, included in EC 4.1.1.28: aromatic-L-amino-acid decarboxylase: sulfoalanine decarboxylase: pantothenoylcysteine decarboxylase

Pantothenoylcysteine decarboxylase

In enzymology, a pantothenoylcysteine decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, N--L-cysteine, and two products, pantetheine and CO2....

: phosphoenolpyruvate carboxylase

Phosphoenolpyruvate carboxylase

Phosphoenolpyruvate carboxylase is an enzyme in the family of carboxy-lyases that catalyzes the addition of bicarbonate to phosphoenolpyruvate to form the four-carbon compound oxaloacetate:This reaction is used for carbon fixation in so-called "CAM" and "C4" plants where it plays a key role in...

: phosphoenolpyruvate carboxykinase (GTP): diphosphomevalonate decarboxylase

Diphosphomevalonate decarboxylase

In enzymology, a diphosphomevalonate decarboxylase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are ATP and -5-diphosphomevalonate, whereas its 4 products are ADP, phosphate, isopentenyl diphosphate, and CO2....

: dehydro-L-gulonate decarboxylase

Dehydro-L-gulonate decarboxylase

In enzymology, a dehydro-L-gulonate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3-dehydro-L-gulonate, and two products, L-xylulose and CO2....

: UDP-glucuronate decarboxylase

UDP-glucuronate decarboxylase

In enzymology, an UDP-glucuronate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, UDP-D-glucuronate, and two products, UDP-D-xylose and CO2....

: phosphopantothenoylcysteine decarboxylase

Phosphopantothenoylcysteine decarboxylase

In enzymology, a phosphopantothenoylcysteine decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, N-[-4'-phosphopantothenoyl]-L-cysteine, and two products, pantotheine 4'-phosphate and CO2....

: uroporphyrinogen decarboxylase: phosphoenolpyruvate carboxykinase (diphosphate): ribulose-bisphosphate carboxylase: hydroxypyruvate decarboxylase

Hydroxypyruvate decarboxylase

In enzymology, a hydroxypyruvate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, hydroxypyruvate, and two products, glycolaldehyde and CO2....

: methylmalonyl-CoA decarboxylase

Methylmalonyl-CoA decarboxylase

In enzymology, a methylmalonyl-CoA decarboxylase is an enzyme that catalyzes the chemical reaction-methylmalonyl-CoA \rightleftharpoons propanoyl-CoA + CO2Hence, this enzyme has one substrate, -methylmalonyl-CoA, and two products, propanoyl-CoA and CO2....

: carnitine decarboxylase

Carnitine decarboxylase

In enzymology, a carnitine decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, carnitine, and two products, 2-methylcholine and CO2....

: phenylpyruvate decarboxylase

Phenylpyruvate decarboxylase

In enzymology, a phenylpyruvate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, phenylpyruvate, and two products, phenylacetaldehyde and CO2....

: 4-carboxymuconolactone decarboxylase

4-carboxymuconolactone decarboxylase

In enzymology, a 4-carboxymuconolactone decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate, and two products, 4,5-dihydro-5-oxofuran-2-acetate and CO2....

: aminocarboxymuconate-semialdehyde decarboxylase

Aminocarboxymuconate-semialdehyde decarboxylase

In enzymology, an aminocarboxymuconate-semialdehyde decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2-amino-3-but-2-enedioate, and two products, 2-aminomuconate semialdehyde and CO2....

: o-pyrocatechuate decarboxylase

O-pyrocatechuate decarboxylase

In enzymology, an o-pyrocatechuate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2,3-dihydroxybenzoate, and two products, catechol and CO2....

: tartronate-semialdehyde synthase

Tartronate-semialdehyde synthase

In enzymology, a tartronate-semialdehyde synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, glyoxylate, and two products, tartronate semialdehyde and CO2....

: indole-3-glycerol-phosphate synthase

Indole-3-glycerol-phosphate synthase

In enzymology, an indole-3-glycerol-phosphate synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 1--1-deoxy-D-ribulose 5-phosphate, but 3 products: 1-C--glycerol 3-phosphate, CO2, and H2O.This enzyme belongs to the family of lyases, to be specific, the...

: phosphoenolpyruvate carboxykinase (ATP): adenosylmethionine decarboxylase

Adenosylmethionine decarboxylase

Adenosylmethionine decarboxylase is an enzyme that catalyzes the conversion of S-adenosyl methionine to S-adenosylmethioninamine.Polyamines such as spermidine and spermine are essential for cellular growth under most conditions, being implicated in a large number of cellular processes including...

: 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase

3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase

In enzymology, a 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3-hydroxy-2-methylpyridine-4,5-dicarboxylate, and two products, 3-hydroxy-2-methylpyridine-5-carboxylate and CO2.This enzyme belongs...

: 6-methylsalicylate decarboxylase

6-methylsalicylate decarboxylase

In enzymology, a 6-methylsalicylate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 6-methylsalicylate, and two products, 3-cresol and CO2....

: phenylalanine decarboxylase

Phenylalanine decarboxylase

In enzymology, a phenylalanine decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-phenylalanine, and two products, phenylethylamine and CO2....

: dihydroxyfumarate decarboxylase

Dihydroxyfumarate decarboxylase

In enzymology, a dihydroxyfumarate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, dihydroxyfumarate, and two products, tartronate semialdehyde and CO2....

: 4,5-dihydroxyphthalate decarboxylase

4,5-dihydroxyphthalate decarboxylase

In enzymology, a 4,5-dihydroxyphthalate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 4,5-dihydroxyphthalate, and two products, 3,4-dihydroxybenzoate and CO2....

: 3-oxolaurate decarboxylase

3-oxolaurate decarboxylase

In enzymology, a 3-oxolaurate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3-oxododecanoate, and two products, 2-undecanone and CO2....

: methionine decarboxylase

Methionine decarboxylase

In enzymology, a methionine decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-methionine, and two products, 3-methylthiopropanamine and CO2....

: orsellinate decarboxylase

Orsellinate decarboxylase

In enzymology, an orsellinate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2,4-dihydroxy-6-methylbenzoate, and two products, orcinol and CO2....

: gallate decarboxylase

Gallate decarboxylase

In enzymology, a gallate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3,4,5-trihydroxybenzoate, and two products, pyrogallol and CO2....

: stipitatonate decarboxylase

Stipitatonate decarboxylase

In enzymology, a stipitatonate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, stipitatonate, and two products, stipitatate and CO2....

: 4-hydroxybenzoate decarboxylase

4-hydroxybenzoate decarboxylase

In enzymology, a 4-hydroxybenzoate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 4-hydroxybenzoate, and two products, phenol and CO2....

: gentisate decarboxylase

Gentisate decarboxylase

In enzymology, a gentisate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2,5-dihydroxybenzoate, and two products, hydroquinone and CO2....

: protocatechuate decarboxylase

Protocatechuate decarboxylase

In enzymology, a protocatechuate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3,4-dihydroxybenzoate, and two products, catechol and CO2....

: 2,2-dialkylglycine decarboxylase (pyruvate)

2,2-dialkylglycine decarboxylase (pyruvate)

In enzymology, a 2,2-dialkylglycine decarboxylase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2,2-dialkylglycine and pyruvate, whereas its 3 products are dialkyl ketone, CO2, and L-alanine....

: phosphatidylserine decarboxylase

Phosphatidylserine decarboxylase

In enzymology, a phosphatidylserine decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, phosphatidyl-L-serine, and two products, phosphatidylethanolamine and CO2....

: uracil-5-carboxylate decarboxylase

Uracil-5-carboxylate decarboxylase

In enzymology, a uracil-5-carboxylate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, uracil 5-carboxylate, and two products, uracil and CO2....

: UDP-galacturonate decarboxylase

UDP-galacturonate decarboxylase

In enzymology, an UDP-galacturonate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, UDP-D-galacturonate, and two products, UDP-L-arabinose and CO2....

: 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase

5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase

In enzymology, a 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 5-oxopent-3-ene-1,2,5-tricarboxylate, and two products, 2-oxohept-3-enedioate and CO2....

: 3,4-dihydroxyphthalate decarboxylase

3,4-dihydroxyphthalate decarboxylase

In enzymology, a 3,4-dihydroxyphthalate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3,4-dihydroxyphthalate, and two products, 3,4-dihydroxybenzoate and CO2....

: glutaconyl-CoA decarboxylase

Glutaconyl-CoA decarboxylase

In enzymology, a glutaconyl-CoA decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 4-carboxybut-2-enoyl-CoA, and two products, but-2-enoyl-CoA and CO2....

: 2-oxoglutarate decarboxylase

2-oxoglutarate decarboxylase

In enzymology, a 2-oxoglutarate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2-oxoglutarate, and two products, succinate semialdehyde and CO2....

: branched-chain-2-oxoacid decarboxylase

Branched-chain-2-oxoacid decarboxylase

In enzymology, a branched-chain-2-oxoacid decarboxylase is an enzyme that catalyzes the chemical reaction-3-methyl-2-oxopentanoate \rightleftharpoons 2-methylbutanal + CO2...

: tartrate decarboxylase

Tartrate decarboxylase

In enzymology, a tartrate decarboxylase is an enzyme that catalyzes the chemical reaction-tartrate \rightleftharpoons D-glycerate + CO2Hence, this enzyme has one substrate, -tartrate, and two products, D-glycerate and CO2....

: indolepyruvate decarboxylase

Indolepyruvate decarboxylase

In enzymology, an indolepyruvate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3-pyruvate, and two products, 2-acetaldehyde and CO2....

: 5-guanidino-2-oxopentanoate decarboxylase

5-guanidino-2-oxopentanoate decarboxylase

In enzymology, a 5-guanidino-2-oxopentanoate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 5-guanidino-2-oxo-pentanoate, and two products, 4-guanidinobutanal and CO2....

: arylmalonate decarboxylase

Arylmalonate decarboxylase

In enzymology, an arylmalonate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2-aryl-2-methylmalonate, and two products, 2-arylpropanoate and CO2....

: 4-oxalocrotonate decarboxylase

4-oxalocrotonate decarboxylase

In enzymology, a 4-oxalocrotonate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 4-oxalocrotonate, and two products, 2-oxopent-4-enoate and CO2....

: acetylenedicarboxylate decarboxylase

Acetylenedicarboxylate decarboxylase

In enzymology, an acetylenedicarboxylate decarboxylase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are acetylenedicarboxylate and H2O, whereas its two products are pyruvate and CO2....

: sulfopyruvate decarboxylase

Sulfopyruvate decarboxylase

In enzymology, a sulfopyruvate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3-sulfopyruvate, and two products, 2-sulfoacetaldehyde and CO2....

: 4-hydroxyphenylpyruvate decarboxylase

4-hydroxyphenylpyruvate decarboxylase

In enzymology, a 4-hydroxyphenylpyruvate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 4-hydroxyphenylpyruvate, and two products, 4-hydroxyphenylacetaldehyde and CO2....

: threonine-phosphate decarboxylase

Threonine-phosphate decarboxylase

In enzymology, a threonine-phosphate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-threonine O-3-phosphate, and two products, -1-aminopropan-2-yl phosphate and CO2....

: phosphonopyruvate decarboxylase

Phosphonopyruvate decarboxylase

In enzymology, a phosphonopyruvate decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3-phosphonopyruvate, and two products, 2-phosphonoacetaldehyde and CO2....

: 4-hydroxyphenylacetate decarboxylase

4-hydroxyphenylacetate decarboxylase

In enzymology, a 4-hydroxyphenylacetate decarboxylase is an enzyme that catalyzes the chemical reactionacetate + H+ \rightleftharpoons 4-methylphenol + CO2...

: D-dopachrome decarboxylase

D-dopachrome decarboxylase

In enzymology, a D-dopachrome decarboxylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, D-dopachrome, and two products, 5,6-dihydroxyindole and CO2....

: 3-dehydro-L-gulonate-6-phosphate decarboxylase

3-dehydro-L-gulonate-6-phosphate decarboxylase

In enzymology, a 3-dehydro-L-gulonate-6-phosphate decarboxylase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-dehydro-L-gulonate 6-phosphate and H+, whereas its two products are L-xylulose 5-phosphate and CO2....

EC 4.1.2: Aldehyde-Lyases

: deleted, included in EC 4.1.3.16: ketotetrose-phosphate aldolase

Ketotetrose-phosphate aldolase

In enzymology, a ketotetrose-phosphate aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, erythrulose 1-phosphate, and two products, glycerone phosphate and formaldehyde....

: deleted: deoxyribose-phosphate aldolase

Deoxyribose-phosphate aldolase

In enzymology, a deoxyribose-phosphate aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2-deoxy-D-ribose 5-phosphate, and two products, D-glyceraldehyde 3-phosphate and acetaldehyde....

: threonine aldolase

Threonine aldolase

In enzymology, a threonine aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-threonine, and two products, glycine and acetaldehyde....

: deleted: deleted, included in EC 4.1.2.13: deleted: phosphoketolase

Phosphoketolase

In enzymology, a phosphoketolase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-xylulose 5-phosphate and phosphate, whereas its 3 products are acetyl phosphate, D-glyceraldehyde 3-phosphate, and H2O....

: mandelonitrile lyase

Mandelonitrile lyase

In enzymology, a mandelonitrile lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, mandelonitrile, and two products, cyanide and benzaldehyde....

: hydroxymandelonitrile lyase

Hydroxymandelonitrile lyase

In enzymology, a hydroxymandelonitrile lyase is an enzyme that catalyzes the chemical reaction-4-hydroxymandelonitrile \rightleftharpoons cyanide + 4-hydroxybenzaldehyde...

: 2-dehydropantoate aldolase

2-dehydropantoate aldolase

In enzymology, a 2-dehydropantoate aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2-dehydropantoate, and two products, 3-methyl-2-oxobutanoate and formaldehyde....

: fructose-bisphosphate aldolase

Fructose-bisphosphate aldolase

In molecular biology, fructose-bisphosphate aldolase , is a glycolytic enzyme that catalyses the reversible aldol cleavage or condensation of fructose-1,6-bisphosphate into dihydroxyacetone-phosphate and glyceraldehyde 3-phosphate...

: 2-dehydro-3-deoxy-phosphogluconate aldolase

2-dehydro-3-deoxy-phosphogluconate aldolase

In enzymology, a 2-dehydro-3-deoxy-phosphogluconate aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2-dehydro-3-deoxy-D-gluconate 6-phosphate, and two products, pyruvate and D-glyceraldehyde 3-phosphate....

: now EC 2.5.1.54: now EC 2.5.1.55: L-fuculose-phosphate aldolase

L-fuculose-phosphate aldolase

In enzymology, a L-fuculose-phosphate aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-fuculose-1-phosphate, and two products, glycerone phosphate and -lactaldehyde....

: 2-dehydro-3-deoxy-L-pentonate aldolase

2-dehydro-3-deoxy-L-pentonate aldolase

In enzymology, a 2-dehydro-3-deoxy-L-pentonate aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2-dehydro-3-deoxy-L-pentonate, and two products, pyruvate and glycolaldehyde....

: rhamnulose-1-phosphate aldolase

Rhamnulose-1-phosphate aldolase

In enzymology, a rhamnulose-1-phosphate aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-rhamnulose 1-phosphate, and two products, glycerone phosphate and -lactaldehyde....

: 2-dehydro-3-deoxyglucarate aldolase

2-dehydro-3-deoxyglucarate aldolase

In enzymology, a 2-dehydro-3-deoxyglucarate aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2-dehydro-3-deoxy-D-glucarate, and two products, pyruvate and tartronate semialdehyde....

: 2-dehydro-3-deoxy-6-phosphogalactonate aldolase

2-dehydro-3-deoxy-6-phosphogalactonate aldolase

In enzymology, a 2-dehydro-3-deoxy-6-phosphogalactonate aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2-dehydro-3-deoxy-D-galactonate 6-phosphate, and two products, pyruvate and D-glyceraldehyde 3-phosphate....

: fructose-6-phosphate phosphoketolase

Fructose-6-phosphate phosphoketolase

In enzymology, a fructose-6-phosphate phosphoketolase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-fructose 6-phosphate and phosphate, whereas its 3 products are acetyl phosphate, D-erythrose 4-phosphate, and H2O.This enzyme belongs to the family...

: 3-deoxy-D-manno-octulosonate aldolase

3-deoxy-D-manno-octulosonate aldolase

In enzymology, a 3-deoxy-D-manno-octulosonate aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3-deoxy-D-manno-octulosonate, and two products, pyruvate and D-arabinose....

: dimethylaniline-N-oxide aldolase

Dimethylaniline-N-oxide aldolase

In enzymology, a dimethylaniline-N-oxide aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, N,N-dimethylaniline N-oxide, and two products, N-methylaniline and formaldehyde....

: dihydroneopterin aldolase

Dihydroneopterin aldolase

In enzymology, a dihydroneopterin aldolase is an enzyme that catalyzes the chemical reactionThus, the substrate of this enzyme is 2-amino-4-hydroxy-6--7,8-dihydropteridine, whereas its two products are 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and glycolaldehyde.This enzyme belongs...

: phenylserine aldolase

Phenylserine aldolase

In enzymology, a phenylserine aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-threo-3-phenylserine, and two products, glycine and benzaldehyde....

: sphinganine-1-phosphate aldolase

Sphinganine-1-phosphate aldolase

In enzymology, a sphinganine-1-phosphate aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, sphinganine 1-phosphate, and two products, phosphoethanolamine and palmitaldehyde....

: 2-dehydro-3-deoxy-D-pentonate aldolase

2-dehydro-3-deoxy-D-pentonate aldolase

In enzymology, a 2-dehydro-3-deoxy-D-pentonate aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2-dehydro-3-deoxy-D-pentonate, and two products, pyruvate and glycolaldehyde....

: 5-dehydro-2-deoxyphosphogluconate aldolase

5-dehydro-2-deoxyphosphogluconate aldolase

In enzymology, a 5-dehydro-2-deoxyphosphogluconate aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 5-dehydro-2-deoxy-D-gluconate 6-phosphate, and two products, glycerone phosphate and malonate semialdehyde....

: 17a-hydroxyprogesterone aldolase: deleted, included in EC 4.1.3.16: trimethylamine-oxide aldolase

Trimethylamine-oxide aldolase

In enzymology, a trimethylamine-oxide aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, trimethylamine N-oxide, and two products, dimethylamine and formaldehyde....

: fucosterol-epoxide lyase

Fucosterol-epoxide lyase

In enzymology, a fucosterol-epoxide lyase is an enzyme that catalyzes the chemical reaction-fucosterol epoxide \rightleftharpoons desmosterol + acetaldehyde...

: 4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase

4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase

In enzymology, a 4--2-oxobut-3-enoate aldolase is an enzyme that catalyzes the chemical reaction-4--2-oxobut-3-enoate + H2O \rightleftharpoons 2-formylbenzoate + pyruvate...

: propioin synthase

Propioin synthase

In enzymology, a propioin synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 4-hydroxy-3-hexanone, and one product, propanal....

: lactate aldolase

Lactate aldolase

In enzymology, a lactate aldolase is an enzyme that catalyzes the chemical reaction-lactate \rightleftharpoons formate + acetaldehydeHence, this enzyme has one substrate, -lactate, and two products, formate and acetaldehyde....

: hydroxynitrilase

Hydroxynitrilase

In enzymology, a hydroxynitrilase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, acetone cyanohydrin, and two products, cyanide and acetone....

: benzoin aldolase

Benzoin aldolase

In enzymology, a benzoin aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2-hydroxy-1,2-diphenylethanone, and one product, benzaldehyde....

: Deleted, same as EC 4.1.2.37: tagatose-bisphosphate aldolase

Tagatose-bisphosphate aldolase

In enzymology, a tagatose-bisphosphate aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, D-tagatose 1,6-bisphosphate, and two products, glycerone phosphate and D-glyceraldehyde 3-phosphate....

: vanillin synthase

Vanillin synthase

In enzymology, a vanillin synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3-hydroxy-3-propanoyl-CoA, and two products, vanillin and acetyl-CoA....

EC 4.1.3: Oxo-Acid-Lyases

: isocitrate lyase

Isocitrate lyase

Isocitrate lyase , or ICL, is an enzyme in the glyoxylate cycle that catalyzes the cleavage of isocitrate to succinate and glyoxylate. Together with malate synthase, it bypasses the two decarboxylation steps of the tricarboxylic acid cycle and is used by bacteria, fungi, and plants.The systematic...

: now EC 2.3.3.9: N-acetylneuraminate lyase

N-acetylneuraminate lyase

In enzymology, a N-acetylneuraminate lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, N-acetylneuraminate, and two products, N-acetyl-D-mannosamine and pyruvate....

: hydroxymethylglutaryl-CoA lyase: now EC 2.3.3.10: citrate (pro-3S)-lyase

Citrate (pro-3S)-lyase

In enzymology, a citrate -lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, citrate, and two products, acetate and oxaloacetate....

: now EC 2.3.3.1: now EC 2.3.3.8: now EC 2.3.3.11: now EC 2.3.3.7: now EC 2.3.3.12: now EC 2.3.3.13: oxalomalate lyase

Oxalomalate lyase

In enzymology, an oxalomalate lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3-oxalomalate, and two products, oxaloacetate and glyoxylate....

: 3-hydroxyaspartate aldolase

3-hydroxyaspartate aldolase

In enzymology, a 3-hydroxyaspartate aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, erythro-3-hydroxy-Ls-aspartate, and two products, glycine and glyoxylate....

: now EC 2.2.1.5: 4-hydroxy-2-oxoglutarate aldolase

4-hydroxy-2-oxoglutarate aldolase

In enzymology, a 4-hydroxy-2-oxoglutarate aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 4-hydroxy-2-oxoglutarate, and two products, pyruvate and glyoxylate....

: 4-hydroxy-4-methyl-2-oxoglutarate aldolase

4-hydroxy-4-methyl-2-oxoglutarate aldolase

In enzymology, a 4-hydroxy-4-methyl-2-oxoglutarate aldolase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 4-hydroxy-4-methyl-2-oxoglutarate, and one product, pyruvate....

: now EC 2.2.1.6: now EC 2.5.1.56: now EC 2.5.1.57: now EC 2.3.3.14: citramalate lyase

Citramalate lyase

In enzymology, a citramalate lyase is an enzyme that catalyzes the chemical reaction-2-hydroxy-2-methylbutanedioate \rightleftharpoons acetate + pyruvate...

: now EC 2.3.3.2: malyl-CoA lyase

Malyl-CoA lyase

In enzymology, a malyl-CoA lyase is an enzyme that catalyzes the chemical reaction-3-carboxy-3-hydroxypropanoyl-CoA \rightleftharpoons acetyl-CoA + glyoxylate...

: citramalyl-CoA lyase

Citramalyl-CoA lyase

In enzymology, a citramalyl-CoA lyase is an enzyme that catalyzes the chemical reaction-citramalyl-CoA \rightleftharpoons acetyl-CoA + pyruvateHence, this enzyme has one substrate, -citramalyl-CoA, and two products, acetyl-CoA and pyruvate....

: 3-hydroxy-3-isohexenylglutaryl-CoA lyase

3-hydroxy-3-isohexenylglutaryl-CoA lyase

In enzymology, a 3-hydroxy-3-isohexenylglutaryl-CoA lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3-hydroxy-3-glutaryl-CoA, and two products, 7-methyl-3-oxooct-6-enoyl-CoA and acetate....

: anthranilate synthase

Anthranilate synthase

In enzymology, an anthranilate synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are chorismate and L-glutamine, whereas its 3 products are anthranilate, pyruvate, and L-glutamate....

: now EC 2.3.3.3: now EC 2.3.3.4: methylisocitrate lyase

Methylisocitrate lyase

In enzymology, a methylisocitrate lyase is an enzyme that catalyzes the chemical reaction-3-hydroxybutane-1,2,3-tricarboxylate \rightleftharpoons pyruvate + succinate...

: now EC 2.3.3.5: 2,3-dimethylmalate lyase

2,3-dimethylmalate lyase

In enzymology, a 2,3-dimethylmalate lyase is an enzyme that catalyzes the chemical reaction-2,3-dimethylmalate \rightleftharpoons propanoate + pyruvate...

: now EC 2.3.3.6: citryl-CoA lyase

Citryl-CoA lyase

In enzymology, a citryl-CoA lyase is an enzyme that catalyzes the chemical reaction-citryl-CoA \rightleftharpoons acetyl-CoA + oxaloacetateHence, this enzyme has one substrate, -citryl-CoA, and two products, acetyl-CoA and oxaloacetate....

: (1-hydroxycyclohexan-1-yl)acetyl-CoA lyase

(1-hydroxycyclohexan-1-yl)acetyl-CoA lyase

In enzymology, a acetyl-CoA lyase is an enzyme that catalyzes the chemical reactionacetyl-CoA \rightleftharpoons acetyl-CoA + cyclohexanone...

: naphthoate synthase

Naphthoate synthase

In enzymology, a naphthoate synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, o-succinylbenzoyl-CoA, and two products, CoA and 1,4-dihydroxy-2-naphthoate....

: now EC 2.2.1.7: aminodeoxychorismate lyase

Aminodeoxychorismate lyase

In enzymology, an aminodeoxychorismate lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 4-amino-4-deoxychorismate, and two products, 4-aminobenzoate and pyruvate....

EC 4.1.99: Other Carbon-Carbon Lyases

: tryptophanase

Tryptophanase

In enzymology, a tryptophanase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-tryptophan and H2O, whereas its 3 products are indole, pyruvate, and NH3....

: tyrosine phenol-lyase

Tyrosine phenol-lyase

In enzymology, a tyrosine phenol-lyase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-tyrosine and H2O, whereas its 3 products are phenol, pyruvate, and NH3....

: deoxyribodipyrimidine photo-lyase

Deoxyribodipyrimidine photo-lyase

In enzymology, a deoxyribodipyrimidine photo-lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, cyclobutadipyrimidine , and one product, pyrimidine residues ....

: now EC 3.5.99.7: octadecanal decarbonylase

Octadecanal decarbonylase

In enzymology, an octadecanal decarbonylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, octadecanal, and two products, heptadecane and CO....

: now EC 4.2.3.6: now EC 4.2.3.9: now EC 4.2.3.14: now EC 4.2.3.15: now EC 4.2.3.16: benzylsuccinate synthase

Benzylsuccinate synthase

In enzymology, a benzylsuccinate synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, benzylsuccinate, and two products, toluene and fumarate....

EC 4.2.1: Hydro-Lyases

: carbonate dehydratase: fumarate hydratase: aconitate hydratase: citrate dehydratase

Citrate dehydratase

In enzymology, a citrate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, citrate, and two products, cis-aconitate and H2O....

: arabinonate dehydratase

Arabinonate dehydratase

In enzymology, an arabinonate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, D-arabinonate, and two products, 2-dehydro-3-deoxy-D-arabinonate and H2O....

: galactonate dehydratase

Galactonate dehydratase

In enzymology, a galactonate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, D-galactonate, and two products, 2-dehydro-3-deoxy-D-galactonate and H2O....

: altronate dehydratase

Altronate dehydratase

In enzymology, an altronate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, D-altronate, and two products, 2-dehydro-3-deoxy-D-gluconate and H2O....

: mannonate dehydratase

Mannonate dehydratase

In enzymology, a mannonate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, D-mannonate, and two products, 2-dehydro-3-deoxy-D-gluconate and H2O....

: dihydroxy-acid dehydratase

Dihydroxy-acid dehydratase

In enzymology, a dihydroxy-acid dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2,3-dihydroxy-3-methylbutanoate, and two products, 3-methyl-2-oxobutanoate and H2O....

: 3-dehydroquinate dehydratase

3-dehydroquinate dehydratase

In enzymology, a 3-dehydroquinate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3-dehydroquinate, and two products, 3-dehydroshikimate and H2O....

: phosphopyruvate hydratase

Phosphopyruvate hydratase

In enzymology, a phosphopyruvate hydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2-phospho-D-glycerate, and two products, phosphoenolpyruvate and H2O....

: phosphogluconate dehydratase

Phosphogluconate dehydratase

In enzymology, a phosphogluconate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 6-phospho-D-gluconate, and two products, 2-dehydro-3-deoxy-6-phospho-D-gluconate and H2O....

: now EC 4.3.1.17: now EC 4.3.1.18: now EC 4.4.1.1: now EC 4.3.1.19: enoyl-CoA hydratase

Enoyl-CoA hydratase

Enoyl-CoA hydratase is an enzyme that hydrates the double bond between the second and third carbons on acyl-CoA. This enzyme, also known as crotonase, is essential to metabolizing fatty acids to produce both acetyl CoA and energy. Note the crystal structure at right of enoyl-coa hydratase from a...

: methylglutaconyl-CoA hydratase

Methylglutaconyl-CoA hydratase

Methylglutaconyl-CoA hydratase is an enzyme associated with 3-Methylglutaconic aciduria....

: imidazoleglycerol-phosphate dehydratase

Imidazoleglycerol-phosphate dehydratase

In enzymology, an imidazoleglycerol-phosphate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, D-erythro-1-glycerol 3-phosphate, and two products, 3--2-oxopropyl phosphate and H2O.This enzyme belongs to the family of lyases, specifically the...

: tryptophan synthase

Tryptophan synthase

Tryptophan synthase or tryptophan synthetase is an enzyme that catalyzes the final two steps in the biosynthesis of tryptophan. It is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae. However, it is absent from animalia. It is typically found as an α2β2 tetramer...

: now EC 4.2.1.22: cystathionine b-synthase: deleted: porphobilinogen synthase

Porphobilinogen synthase

Porphobilinogen synthase synthesizes porphobilinogen through the asymmetric condensation of two molecules of aminolevulinic acid...

: L-arabinonate dehydratase

L-arabinonate dehydratase

In enzymology, a L-arabinonate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-arabinonate, and two products, 2-dehydro-3-deoxy-L-arabinonate and H2O....

: now EC 4.3.1.21: acetylenecarboxylate hydratase

Acetylenecarboxylate hydratase

In enzymology, an acetylenecarboxylate hydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3-oxopropanoate, and two products, propynoate and H2O....

: propanediol dehydratase

Propanediol dehydratase

In enzymology, a propanediol dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 1,2-propanediol, and two products, propanal and H2O....

: now EC 4.99.1.6: glycerol dehydratase

Glycerol dehydratase

In enzymology, a glycerol dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, glycerol, and two products, 3-hydroxypropanal and H2O....

: maleate hydratase

Maleate hydratase

In enzymology, a maleate hydratase is an enzyme that catalyzes the chemical reaction-malate \rightleftharpoons maleate + H2OHence, this enzyme has one substrate, -malate, and two products, maleate and H2O....

: L(+)-tartrate dehydratase

L(+)-tartrate dehydratase

In enzymology, a L-tartrate dehydratase is an enzyme that catalyzes the chemical reaction-tartrate \rightleftharpoons oxaloacetate + H2OHence, this enzyme has one substrate, -tartrate, and two products, oxaloacetate and H2O....

: 3-isopropylmalate dehydratase

3-isopropylmalate dehydratase

3-Isopropylmalate dehydratase is an aconitase homologue....

: (S)-2-methylmalate dehydratase

(S)-2-methylmalate dehydratase

In enzymology, a -2-methylmalate dehydratase is an enzyme that catalyzes the chemical reaction-2-methylmalate \rightleftharpoons 2-methylfumarate + H2OHence, this enzyme has one substrate, -2-methylmalate, and two products, 2-methylfumarate and H2O....

: (R)-2-methylmalate dehydratase

(R)-2-methylmalate dehydratase

In enzymology, a -2-methylmalate dehydratase is an enzyme that catalyzes the chemical reaction-2-methylmalate \rightleftharpoons 2-methylmaleate + H2OHence, this enzyme has one substrate, -2-methylmalate, and two products, 2-methylmaleate and H2O....

: homoaconitate hydratase

Homoaconitate hydratase

In enzymology, a homoaconitate hydratase is an enzyme that catalyzes the chemical reaction-1-hydroxybutane-1,2,4-tricarboxylate \rightleftharpoons -but-1-ene-1,2,4-tricarboxylate + H2O...

: now EC 3.3.2.4: now EC 4.3.1.20: gluconate dehydratase

Gluconate dehydratase

In enzymology, a gluconate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, D-gluconate, and two products, 2-dehydro-3-deoxy-D-gluconate and H2O....

: glucarate dehydratase

Glucarate dehydratase

In enzymology, a glucarate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, D-glucarate, and two products, 5-dehydro-4-deoxy-D-glucarate and H2O....

: 5-dehydro-4-deoxyglucarate dehydratase

5-dehydro-4-deoxyglucarate dehydratase

In enzymology, a 5-dehydro-4-deoxyglucarate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 5-dehydro-4-deoxy-D-glucarate, but 3 products: 2,5-dioxopentanoate, H2O, and CO2.-Enzyme class:...

: galactarate dehydratase

Galactarate dehydratase

In enzymology, a galactarate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, D-galactarate, and two products, 5-dehydro-4-deoxy-D-glucarate and H2O....

: 2-dehydro-3-deoxy-L-arabinonate dehydratase

2-dehydro-3-deoxy-L-arabinonate dehydratase

In enzymology, a 2-dehydro-3-deoxy-L-arabinonate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2-dehydro-3-deoxy-L-arabinonate, and two products, 2,5-dioxopentanoate and H2O....

: myo-inosose-2 dehydratase

Myo-inosose-2 dehydratase

In enzymology, a myo-inosose-2 dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2,4,6/3,5-pentahydroxycyclohexanone, and two products, 3,5/4-trihydroxycyclohexa-1,2-dione and H2O....

: CDP-glucose 4,6-dehydratase

CDP-glucose 4,6-dehydratase

In the field of enzymology, a CDP-glucose 4,6-dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, CDP-glucose, and two products, CDP-4-dehydro-6-deoxy-D-glucose and H2O....

: dTDP-glucose 4,6-dehydratase

DTDP-glucose 4,6-dehydratase

In enzymology, a dTDP-glucose 4,6-dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, dTDP-glucose, and two products, dTDP-4-dehydro-6-deoxy-D-glucose and H2O....

: GDP-mannose 4,6-dehydratase

GDP-mannose 4,6-dehydratase

In enzymology, a GDP-mannose 4,6-dehydratase is an mannosyltransferase enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, GDP-mannose, and two products, GDP-4-dehydro-6-deoxy-D-mannose and H2O....

: D-glutamate cyclase

D-glutamate cyclase

In enzymology, a D-glutamate cyclase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, D-glutamate, and two products, 5-oxo-D-proline and H2O....

: urocanate hydratase

Urocanate hydratase

Urocanase is the enzyme that catalyzes the second step in the degradation of histidine, the hydration of urocanate into imidazolonepropionate....

: pyrazolylalanine synthase

Pyrazolylalanine synthase

In enzymology, a pyrazolylalanine synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-serine and pyrazole, whereas its two products are 3--L-alanine and H2O....

: prephenate dehydratase

Prephenate dehydratase

In enzymology, a prephenate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, prephenate, but 3 products: phenylpyruvate, H2O, and CO2....

: dihydrodipicolinate synthase

Dihydrodipicolinate synthase

In enzymology, a dihydrodipicolinate synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-aspartate 4-semialdehyde and pyruvate, whereas its two products are -2,3-dihydropyridine-2,6-dicarboxylate and H2O.This enzyme belongs to the family of...

: oleate hydratase

Oleate hydratase

In enzymology, an oleate hydratase is an enzyme that catalyzes the chemical reaction-10-hydroxystearate \rightleftharpoons oleate + H2OHence, this enzyme has one substrate, -10-hydroxystearate, and two products, oleate and H2O....

: lactoyl-CoA dehydratase

Lactoyl-CoA dehydratase

In enzymology, a lactoyl-CoA dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, lactoyl-CoA, and two products, acryloyl-CoA and H2O....

: 3-hydroxybutyryl-CoA dehydratase

3-hydroxybutyryl-CoA dehydratase

In enzymology, a 3-hydroxybutyryl-CoA dehydratase is an enzyme that catalyzes the chemical reaction-3-hydroxybutanoyl-CoA \rightleftharpoons crotonoyl-CoA + H2O...

: itaconyl-CoA hydratase

Itaconyl-CoA hydratase

In enzymology, an itaconyl-CoA hydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, citramalyl-CoA, and two products, itaconyl-CoA and H2O....

: isohexenylglutaconyl-CoA hydratase

Isohexenylglutaconyl-CoA hydratase

In enzymology, an isohexenylglutaconyl-CoA hydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3-hydroxy-3-glutaryl-CoA, and two products, 3-pent-2-enedioyl-CoA and H2O.This enzyme belongs to the family of lyases, specifically the hydro-lyases, which...

: crotonoyl-(acyl-carrier-protein) hydratase

Crotonoyl-(acyl-carrier-protein) hydratase

In enzymology, a crotonoyl-[acyl-carrier-protein] hydratase is an enzyme that catalyzes the chemical reaction-3-hydroxybutanoyl-[acyl-carrier-protein] \rightleftharpoons but-2-enoyl-[acyl-carrier-protein] + H2O...

: 3-hydroxyoctanoyl-(acyl-carrier-protein) dehydratase

3-hydroxyoctanoyl-(acyl-carrier-protein) dehydratase

In enzymology, a 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase is an enzyme that catalyzes the chemical reaction-3-hydroxyoctanoyl-[acyl-carrier-protein] \rightleftharpoons oct-2-enoyl-[acyl-carrier-protein] + H2O...

: 3-hydroxydecanoyl-(acyl-carrier-protein) dehydratase: 3-hydroxypalmitoyl-(acyl-carrier-protein) dehydratase

3-hydroxypalmitoyl-(acyl-carrier-protein) dehydratase

In enzymology, a 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase is an enzyme that catalyzes the chemical reaction-3-hydroxypalmitoyl-[acyl-carrier-protein] \rightleftharpoons hexadec-2-enoyl-[acyl-carrier-protein] + H2O...

: 5a-hydroxysteroid dehydratase: now EC 3.3.2.3: now EC 3.3.2.3: 3-cyanoalanine hydratase

3-cyanoalanine hydratase

In enzymology, a 3-cyanoalanine hydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-asparagine, and two products, 3-cyanoalanine and H2O....

: cyanide hydratase

Cyanide hydratase

In enzymology, a cyanide hydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, formamide, and two products, cyanide and H2O....

: D-fuconate dehydratase

D-fuconate dehydratase

In enzymology, a D-fuconate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, D-fuconate, and two products, 2-dehydro-3-deoxy-D-fuconate and H2O....

: L-fuconate dehydratase

L-fuconate dehydratase

In enzymology, a L-fuconate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-fuconate, and two products, 2-dehydro-3-deoxy-L-fuconate and H2O....

: cyanamide hydratase

Cyanamide hydratase

In enzymology, a cyanamide hydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, urea, and two products, cyanamide and H2O....

: pseudouridylate synthase

Pseudouridylate synthase

In enzymology, a pseudouridylate synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are uracil and D-ribose 5-phosphate, whereas its two products are pseudouridine 5'-phosphate and H2O....

: identical to EC 4.2.1.27: now EC 4.1.1.78: protoaphin-aglucone dehydratase (cyclizing)

Protoaphin-aglucone dehydratase (cyclizing)

In enzymology, a protoaphin-aglucone dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, protoaphin aglucone, and two products, xanthoaphin and H2O....

: long-chain-enoyl-CoA hydratase

Long-chain-enoyl-CoA hydratase

In enzymology, a long-chain-enoyl-CoA hydratase is an enzyme that catalyzes the chemical reaction-3-hydroxyacyl-CoA \rightleftharpoons trans-2-enoyl-CoA + H2O...

: uroporphyrinogen-III synthase: UDP-glucose 4,6-dehydratase

UDP-glucose 4,6-dehydratase

In enzymology, an UDP-glucose 4,6-dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, UDP-glucose, and two products, UDP-4-dehydro-6-deoxy-D-glucose and H2O....

: trans-L-3-hydroxyproline dehydratase

Trans-L-3-hydroxyproline dehydratase

In enzymology, a trans-L-3-hydroxyproline dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, trans-L-3-hydroxyproline, and two products, Delta1-pyrroline 2-carboxylate and H2O....

: (S)-norcoclaurine synthase

(S)-norcoclaurine synthase

In enzymology, a -norcoclaurine synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 4-hydroxyphenylacetaldehyde and 4-benzene-1,2-diol, whereas its two products are -norcoclaurine and H2O....

: 2-methylcitrate dehydratase

2-methylcitrate dehydratase

In enzymology, a 2-methylcitrate dehydratase is an enzyme that catalyzes the chemical reaction-2-hydroxybutane-1,2,3-tricarboxylate \rightleftharpoons -but-2-ene-1,2,3-tricarboxylate + H2O...

: 2-oxopent-4-enoate hydratase

2-oxopent-4-enoate hydratase

In enzymology, a 2-oxopent-4-enoate hydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 4-hydroxy-2-oxopentanoate, and two products, 2-oxopent-4-enoate and H2O....

: D(-)-tartrate dehydratase

D(-)-tartrate dehydratase

In enzymology, a D-tartrate dehydratase is an enzyme that catalyzes the chemical reaction-tartrate \rightleftharpoons oxaloacetate + H2OHence, this enzyme has one substrate, -tartrate, and two products, oxaloacetate and H2O....

: xylonate dehydratase

Xylonate dehydratase

In enzymology, a xylonate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, D-xylonate, and two products, 2-dehydro-3-deoxy-D-xylonate and H2O....

: 4-oxalmesaconate hydratase

4-oxalmesaconate hydratase

In enzymology, a 4-oxalmesaconate hydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate, and two products, -4-oxobut-1-ene-1,2,4-tricarboxylate and H2O....

: nitrile hydratase

Nitrile hydratase

In enzymology, nitrile hydratases are mononuclear iron or non-corrinoid cobalt enzymes that catalyse the hydration of diverse nitriles to their corresponding amidesR-C≡N + H2O → R-CNH2-Metal cofactor:...

: dimethylmaleate hydratase

Dimethylmaleate hydratase

In enzymology, a dimethylmaleate hydratase is an enzyme that catalyzes the chemical reaction-2,3-dimethylmalate \rightleftharpoons dimethylmaleate + H2O...

: deleted identical to EC 4.2.1.98: octopamine dehydratase

Octopamine dehydratase

In enzymology, an octopamine dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 1--2-aminoethanol, and two products, 4-hydroxyphenylacetaldehyde and NH3....

: synephrine dehydratase

Synephrine dehydratase

In enzymology, a synephrine dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 1--2-ethanol , and two products, 4-hydroxyphenylacetaldehyde and methylamine....

: carnitine dehydratase

Carnitine dehydratase

In enzymology, a carnitine dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-carnitine, and two products, 4-but-2-enoate and H2O....

: L-rhamnonate dehydratase

L-rhamnonate dehydratase

In enzymology, a L-rhamnonate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-rhamnonate, and two products, 2-dehydro-3-deoxy-L-rhamnonate and H2O....

: arogenate dehydratase

Arogenate dehydratase

In enzymology, an arogenate dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-arogenate, but 3 products: L-phenylalanine, H2O, and CO2....

: hydroperoxide dehydratase

Hydroperoxide dehydratase

In enzymology, a hydroperoxide dehydratase is an enzyme that catalyzes the chemical reaction--hydroperoxyoctadeca-9,11,14-trienoate \rightleftharpoons --12,13-epoxyoctadeca-9,11-dienoate + H2O...

: ATP-dependent NAD(P)H-hydrate dehydratase

ATP-dependent NAD(P)H-hydrate dehydratase

In enzymology, an ATP-dependent NADH-hydrate dehydratase is an enzyme that catalyzes the chemical reactionThe 3 substrates of this enzyme are ATP, -6-beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine, and dinucleotide, whereas its 3 products are ADP, phosphate, and NADH.This enzyme belongs to...

: scytalone dehydratase

Scytalone dehydratase

In enzymology, a scytalone dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, scytalone, and two products, 1,3,8-trihydroxynaphthalene and H2O....

: kievitone hydratase

Kievitone hydratase

In enzymology, a kievitone hydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, kievitone hydrate, and two products, kievitone and H2O....

: 4a-hydroxytetrahydrobiopterin dehydratase

4a-hydroxytetrahydrobiopterin dehydratase

In enzymology, a 4a-hydroxytetrahydrobiopterin dehydratase is an enzyme that catalyzes the chemical reaction-6--5,6,7,8-tetrahydro-4a- hydroxypterin \rightleftharpoons -6--7,8-dihydro-6H-pterin + H2OThus, the two substrates of this enzyme are -6--5,6,7,8-tetrahydro-4a- and...

: phaseollidin hydratase

Phaseollidin hydratase

In enzymology, a phaseollidin hydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, phaseollidin hydrate, and two products, phaseollidin and H2O....

: 16a-hydroxyprogesterone dehydratase: 2-methylisocitrate dehydratase

2-methylisocitrate dehydratase

In enzymology, a 2-methylisocitrate dehydratase is an enzyme that catalyzes the chemical reaction-3-hydroxybutane-1,2,3-tricarboxylate \rightleftharpoons -but-2-ene-1,2,3-tricarboxylate + H2O...

: cyclohexa-1,5-dienecarbonyl-CoA hydratase

Cyclohexa-1,5-dienecarbonyl-CoA hydratase

In enzymology, a cyclohexa-1,5-dienecarbonyl-CoA hydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 6-hydroxycyclohex-1-enecarbonyl-CoA, and two products, cyclohexa-1,5-dienecarbonyl-CoA and H2O....

: trans-feruloyl-CoA hydratase

Trans-feruloyl-CoA hydratase

In enzymology, a trans-feruloyl-CoA hydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 4-hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA, and two products, trans-feruloyl-CoA and H2O....

: now EC 4.2.1.100: cyclohexyl-isocyanide hydratase

Cyclohexyl-isocyanide hydratase

In enzymology, a cyclohexyl-isocyanide hydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, N-cyclohexylformamide, and two products, cyclohexyl isocyanide and H2O....

: cyanate hydratase

Cyanate hydratase

In molecular biology, cyanate hydratase is an enzyme which catalyses the hydrolysis of cyanate. It is also known as cyanate lyase or cyanase.Some bacteria can overcome the toxicity of environmental cyanate by hydrolysis of cyanate by this enzyme...

: 2-hydroxyisoflavanone dehydratase

2-hydroxyisoflavanone dehydratase

In enzymology, a 2-hydroxyisoflavanone dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2,7,4'-trihydroxyisoflavanone, and two products, daidzein and H2O....

: bile-acid 7a-dehydratase: 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA dehydratase

EC 4.2.2: Acting on Polysaccharides

: hyaluronate lyase

Hyaluronate lyase

In enzymology, a hyaluronate lyase is an enzyme that catalyzes the chemical reactionThis enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is hyaluronate lyase. Other names in common use include...

: pectate lyase

Pectate lyase

Pectate lyase is an enzyme involved in the maceration and soft rotting of plant tissue. Pectate lyase is responsible for the eliminative cleavage of pectate, yielding oligosaccharides with 4-deoxy-alpha-D-mann-4-enuronosyl groups at their non-reducing ends. The protein is maximally expressed late...

: poly(b-D-mannuronate) lyase: chondroitin ABC lyase: chondroitin AC lyase

Chondroitin AC lyase

In enzymology, a chondroitin AC lyase is an enzyme that catalyzes the chemical reactionThis enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is chondroitin AC lyase...

: oligogalacturonide lyase

Oligogalacturonide lyase

In enzymology, an oligogalacturonide lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 4--D-galacturonate, and one product, 5-dehydro-4-deoxy-D-glucuronate....

: heparin lyase

Heparin lyase

In enzymology, a heparin lyase is an enzyme that catalyzes the chemical reactionThis enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is heparin lyase. Other names in common use include heparin...

: heparin-sulfate lyase

Heparin-sulfate lyase

In enzymology, a heparin-sulfate lyase is an enzyme that catalyzes the chemical reactionThis enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is heparin-sulfate lyase...

: pectate disaccharide-lyase

Pectate disaccharide-lyase

In enzymology, a pectate disaccharide-lyase is an enzyme that catalyzes the chemical reactionThis enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is -alpha-D-galacturonan...

: pectin lyase

Pectin lyase

In enzymology, a pectin lyase also known as pectolyase is a naturally occurring pectinase a type of enzyme that degrades pectin. It is produced commercially for the food industry from fungi and used to destroy residual fruit starch, known as pectin, in wine and cider...

: poly(a-L-guluronate) lyase: xanthan lyase

Xanthan lyase

In enzymology, a xanthan lyase is an enzyme that catalyzes the chemical reaction of cleaving the beta-D-mannosyl-beta-D-1,4-glucuronosyl bond on the polysaccharide xanthan. This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides...

: exo-(1→4)-α-D-glucan lyase: glucuronan lyase

Glucuronan lyase

In enzymology, a glucuronan lyase is an enzyme that catalyzes the chemical reaction of eliminative cleavage of -beta-D-glucuronans. This produces either oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends, or, if the substrate is completely degraded,...

: anhydrosialidase

Anhydrosialidase

In enzymology, an anhydrosialidase is an enzyme that catalyzes the chemical reactionThis enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is glycoconjugate sialyl-lyase ...

: levan fructotransferase (DFA-IV-forming)

Levan fructotransferase (DFA-IV-forming)

In enzymology, a levan fructotransferase is an enzyme that catalyzes the chemical reactionThis enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is 2,6-beta-D-fructan lyase ...

: inulin fructotransferase (DFA-I-forming)

Inulin fructotransferase (DFA-I-forming)

In enzymology, an inulin fructotransferase is an enzyme that catalyzes the chemical reactionThis enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is 2,1-beta-D-fructan lyase ...

: inulin fructotransferase (DFA-III-forming)

Inulin fructotransferase (DFA-III-forming)

In enzymology, an inulin fructotransferase is an enzyme that catalyzes the chemical reactionThis enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is 2,1-beta-D-fructan lyase ...

: chondroitin B lyase

Chondroitin B lyase

In enzymology, a chondroitin B lyase is an enzyme that catalyzes the chemical reactionThis enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is chondroitin B lyase. Other names in common use include...

EC 4.2.3: Acting on phosphates

: threonine synthase

Threonine synthase

In enzymology, a threonine synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are O-phospho-L-homoserine and H2O, whereas its two products are L-threonine and phosphate....

: ethanolamine-phosphate phospho-lyase

Ethanolamine-phosphate phospho-lyase

In enzymology, an ethanolamine-phosphate phospho-lyase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are ethanolamine phosphate and H2O, whereas its 3 products are acetaldehyde, NH3, and phosphate....

: methylglyoxal synthase

Methylglyoxal synthase

In enzymology, a methylglyoxal synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, glycerone phosphate, and two products, methylglyoxal and phosphate....

: 3-dehydroquinate synthase

3-dehydroquinate synthase

In enzymology, a 3-dehydroquinate synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3-deoxy-arabino-heptulosonate 7-phosphate, and two products, 3-dehydroquinate and phosphate. The protein uses NAD to catalyze the reaction...

: chorismate synthase

Chorismate synthase

In enzymology, a chorismate synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 5-O--3-phosphoshikimate, and two products, chorismate and phosphate....

: trichodiene synthase

Trichodiene synthase

In enzymology, a trichodiene synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, trans,trans-farnesyl diphosphate, and two products, trichodiene and diphosphate....

: pentalenene synthase

Pentalenene synthase

In enzymology, a pentalenene synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2-trans,6-trans-farnesyl diphosphate, and two products, pentalenene and diphosphate....

: casbene synthase

Casbene synthase

In enzymology, a casbene synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, geranylgeranyl diphosphate, and two products, casbene and diphosphate....

: aristolochene synthase

Aristolochene synthase

In enzymology, an aristolochene synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 2-trans,6-trans-farnesyl diphosphate, and two products, aristolochene and diphosphate....

: (-)-endo-fenchol synthase

(-)-endo-fenchol synthase

In enzymology, a -endo-fenchol synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are geranyl diphosphate and H2O, whereas its two products are -endo-fenchol and diphosphate....

: sabinene-hydrate synthase

Sabinene-hydrate synthase

In enzymology, a sabinene-hydrate synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are geranyl diphosphate and H2O, whereas its two products are sabinene hydrate and diphosphate....

: 6-pyruvoyltetrahydropterin synthase

6-pyruvoyltetrahydropterin synthase

In enzymology, a 6-pyruvoyltetrahydropterin synthase is an enzyme that catalyzes the following chemical reaction:Hence, this enzyme has one substrate, 6-[-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydropterin, and two products, 6-pyruvoyl-5,6,7,8-tetrahydropterin and triphosphate.This enzyme...

: (+)-d-cadinene synthase: pinene synthase

Pinene synthase

In enzymology, a pinene synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, geranyl diphosphate, and two products, pinene and diphosphate....

: myrcene synthase

Myrcene synthase

In enzymology, a myrcene synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, geranyl diphosphate, and two products, myrcene and diphosphate....

: (4S)-limonene synthase

(4S)-limonene synthase

In enzymology, a -limonene synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, geranyl diphosphate, and two products, --limonene and diphosphate....

: taxadiene synthase

Taxadiene synthase

In enzymology, a taxadiene synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, geranylgeranyl diphosphate, and two products, taxa-4,11-diene and diphosphate....

: abietadiene synthase

Abietadiene synthase

In enzymology, an abietadiene synthase is an enzyme that catalyzes the chemical reaction-copalyl diphosphate \rightleftharpoons -abietadiene + diphosphate...

: ent-kaurene synthase

Ent-kaurene synthase

In enzymology, an ent-kaurene synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, ent-copalyl diphosphate, and two products, ent-kaurene and diphosphate....

: (R)-limonene synthase

(R)-limonene synthase

In enzymology, a -limonene synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, geranyl diphosphate, and two products, --limonene and diphosphate....

: vetispiradiene synthase

Vetispiradiene synthase

In enzymology, a vetispiradiene synthase is an enzyme of Egyptian henbane that catalyzes the following chemical reaction:Hence, this enzyme has one substrate, trans,trans-farnesyl diphosphate, and two products, vetispiradiene and diphosphate....

EC 4.2.99: Other Carbon-Oxygen Lyases

: now EC 4.2.2.2: now EC 4.2.3.1: now EC 4.2.2.2: now EC 4.2.2.3: deleted: deleted, included in EC 4.2.2.4 and EC 4.2.2.5: now EC 4.2.3.2: now EC 2.5.1.47: now EC 2.5.1.48: now EC 2.5.1.49: now EC 4.2.3.3: carboxymethyloxysuccinate lyase

Carboxymethyloxysuccinate lyase

In enzymology, a carboxymethyloxysuccinate lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, carboxymethyloxysuccinate, and two products, fumarate and glycolate....

: now EC 2.5.1.50: now EC 2.5.1.51: now EC 2.5.1.52: now EC 2.5.1.53: now EC 4.2.99.14: DNA-(apurinic or apyrimidinic site) lyase

DNA-(apurinic or apyrimidinic site) lyase

In enzymology, a DNA- lyase is an enzyme that catalyzes the chemical reactionThis enzyme belongs to the family of lyases, specifically the "catch-all" class of lyases that cleave carbon-oxygen bonds. The systematic name of this enzyme class is DNA- 5'-phosphomonoester-lyase...

: transferred entry, now EC 4.4.1.23

EC 4.3.1: Ammonia-Lyases

: aspartate ammonia-lyase

Aspartate ammonia-lyase

In enzymology, an aspartate ammonia-lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-aspartate, and two products, fumarate and NH3....

: methylaspartate ammonia-lyase

Methylaspartate ammonia-lyase

In enzymology, a methylaspartate ammonia-lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-threo-3-methylaspartate, and two products, mesaconate and NH3....

: histidine ammonia-lyase

Histidine ammonia-lyase

Histidine ammonia-lyase is an enzyme that in humans is encoded by the HAL gene. Histidase converts histidine into ammonia and urocanic acid.- Function :...

: formiminotetrahydrofolate cyclodeaminase: phenylalanine ammonia-lyase

Phenylalanine ammonia-lyase

In enzymology, a phenylalanine ammonia-lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-phenylalanine, and two products, trans-cinnamic acid and ammonia....

: b-alanyl-CoA ammonia-lyase: ethanolamine ammonia-lyase

Ethanolamine ammonia-lyase

In enzymology, an ethanolamine ammonia-lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, ethanolamine, and two products, acetaldehyde and NH3....

: now EC 2.5.1.61: glucosaminate ammonia-lyase

Glucosaminate ammonia-lyase

In enzymology, a glucosaminate ammonia-lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, D-glucosaminate, and two products, 2-dehydro-3-deoxy-D-gluconate and NH3....

: serine-sulfate ammonia-lyase

Serine-sulfate ammonia-lyase

In enzymology, a serine-sulfate ammonia-lyase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-serine O-sulfate and H2O, whereas its 3 products are pyruvate, NH3, and sulfate....

: dihydroxyphenylalanine ammonia-lyase

Dihydroxyphenylalanine ammonia-lyase

In enzymology, a dihydroxyphenylalanine ammonia-lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 3,4-dihydroxy-L-phenylalanine, and two products, trans-caffeate and NH3....

: ornithine cyclodeaminase

Ornithine cyclodeaminase

In enzymology, an ornithine cyclodeaminase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-ornithine, and two products, L-proline and NH3....

: carbamoyl-serine ammonia-lyase

Carbamoyl-serine ammonia-lyase

In enzymology, a carbamoyl-serine ammonia-lyase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are O-carbamoyl-L-serine and H2O, whereas its 3 products are pyruvate, NH3, and CO2....

: 3-aminobutyryl-CoA ammonia-lyase

3-aminobutyryl-CoA ammonia-lyase

In enzymology, a 3-aminobutyryl-CoA ammonia-lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-3-aminobutyryl-CoA, and two products, crotonoyl-CoA and NH3....

: diaminopropionate ammonia-lyase

Diaminopropionate ammonia-lyase

In enzymology, a diaminopropionate ammonia-lyase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 2,3-diaminopropanoate and H2O, whereas its two products are pyruvate and NH3....

: threo-3-hydroxyaspartate ammonia-lyase

Threo-3-hydroxyaspartate ammonia-lyase

In enzymology, a threo-3-hydroxyaspartate ammonia-lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, threo-3-hydroxy-L-aspartate, and two products, oxaloacetate and NH3....

: L-serine ammonia-lyase

L-serine ammonia-lyase

In enzymology, a L-serine ammonia-lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-serine, and two products, pyruvate and NH3....

: D-serine ammonia-lyase

D-serine ammonia-lyase

In enzymology, a D-serine ammonia-lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, D- in common use include D-hydroxyaminoacid dehydratase, D-serine dehydrase, D-hydroxy amino acid dehydratase, D-serine hydrolase, D-serine dehydratase , D-serine...

: threonine ammonia-lyase

Threonine ammonia-lyase

In enzymology, a threonine ammonia-lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, L-threonine, and two products, Alpha-Ketobutyric_acid and NH3....

: erythro-3-hydroxyaspartate ammonia-lyase

Erythro-3-hydroxyaspartate ammonia-lyase

In enzymology, an erythro-3-hydroxyaspartate ammonia-lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, erythro-3-hydroxy-Ls-aspartate, and two products, oxaloacetate and NH3....

: Identical to EC 4.3.1.9

EC 4.3.2: Amidine-Lyases

: argininosuccinate lyase: adenylosuccinate lyase

Adenylosuccinate lyase

Adenylosuccinate lyase is an enzyme that converts adenylosuccinate to AMP and fumarate as part of the purine nucleotide cycle....

: ureidoglycolate lyase

Ureidoglycolate lyase

In enzymology, an ureidoglycolate lyase is an enzyme that catalyzes the chemical reaction-ureidoglycolate \rightleftharpoons glyoxylate + ureaHence, this enzyme has one substrate, -ureidoglycolate, and two products, glyoxylate and urea....

: purine imidazole-ring cyclase

Purine imidazole-ring cyclase

In enzymology, a purine imidazole-ring cyclase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, DNA 4,6-diamino-5-formamidopyrimidine, and two products, DNA adenine and H2O....

: peptidylamidoglycolate lyase

Peptidylamidoglycolate lyase

In enzymology, a peptidylamidoglycolate lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, peptidylamidoglycolate, and two products, peptidyl amide and glyoxylate....

EC 4.3.3: Amine-Lyases

: 3-ketovalidoxylamine C-N-lyase

3-ketovalidoxylamine C-N-lyase

In enzymology, a 3-ketovalidoxylamine C-N-lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 4-nitrophenyl-3-ketovalidamine, and two products, 4-nitroaniline and 5-D--5-C--2,6-dihydroxycyclohex-2-en-1-one.This enzyme belongs to the family of lyases,...

: strictosidine synthase

Strictosidine synthase

Strictosidine synthase a key enzyme in alkaloid biosynthesis. It catalyses the condensation of tryptamine with secologanin to form strictosidine:...

: deacetylisoipecoside synthase

Deacetylisoipecoside synthase

In enzymology, a deacetylisoipecoside synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are deacetylisoipecoside and H2O, whereas its two products are dopamine and secologanin....

: deacetylipecoside synthase

Deacetylipecoside synthase

In enzymology, a deacetylipecoside synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are deacetylipecoside and H2O, whereas its two products are dopamine and secologanin....

EC 4.4: Carbon-Sulfur Lyases

: cystathionine g-lyase: homocysteine desulfhydrase

Homocysteine desulfhydrase

In enzymology, a homocysteine desulfhydrase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-homocysteine and H2O, whereas its 3 products are hydrogen sulfide, NH3, and 2-oxobutanoate....

: dimethylpropiothetin dethiomethylase

Dimethylpropiothetin dethiomethylase

In enzymology, a dimethylpropiothetin dethiomethylase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, S,S-dimethyl-beta-propiothetin, and two products, dimethyl sulfide and acrylate....

: alliin lyase: lactoylglutathione lyase

Lactoylglutathione lyase

In enzymology, a lactoylglutathione lyase is an enzyme that catalyzes the isomerization of hemithioacetal adducts, which are formed in a spontaneous reaction between a glutathionyl group and aldehydes such as methylglyoxal.The systematic name of this enzyme class is -S-lactoylglutathione...

: S-alkylcysteine lyase

S-alkylcysteine lyase

In enzymology, a S-alkylcysteine lyase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are S-alkyl-L-cysteine and H2O, whereas its 3 products are alkyl thiol, NH3, and pyruvate....

: deleted, included in EC 2.5.1.18: cystathionine b-lyase: L-3-cyanoalanine synthase

L-3-cyanoalanine synthase

In enzymology, a L-3-cyanoalanine synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-cysteine and hydrogen cyanide, whereas its two products are L-3-cyanoalanine and hydrogen sulfide....

: cysteine lyase

Cysteine lyase

In enzymology, a cysteine lyase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-cysteine and sulfite, whereas its two products are L-cysteate and hydrogen sulfide....

: methionine g-lyase: deleted: cysteine-S-conjugate b-lyase: 1-aminocyclopropane-1-carboxylate synthase

1-aminocyclopropane-1-carboxylate synthase

In enzymology, a 1-aminocyclopropane-1-carboxylate synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, S-adenosyl-L-methionine, and two products, 1-aminocyclopropane-1-carboxylate and methylthioadenosine....

: D-cysteine desulfhydrase

D-cysteine desulfhydrase

In enzymology, a D-cysteine desulfhydrase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are D-cysteine and H2O, whereas its 3 products are sulfide, NH3, and pyruvate....

: selenocysteine lyase

Selenocysteine lyase

In enzymology, a selenocysteine lyase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are L-selenocysteine and reduced acceptor, whereas its 3 products are selenide, L-alanine, and acceptor....

: holocytochrome-c synthase

Holocytochrome-c synthase

In enzymology, a holocytochrome-c synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, holocytochrome c, and two products, apocytochrome c and heme....

: now EC 1.8.3.5: phosphosulfolactate synthase

Phosphosulfolactate synthase

In enzymology, a phosphosulfolactate synthase is an enzyme that catalyzes the chemical reaction-2-O-phospho-3-sulfolactate \rightleftharpoons phosphoenolpyruvate + hydrogen sulfite...

: leukotriene-C4 synthase

Leukotriene-C4 synthase

In enzymology, a leukotriene-C4 synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, leukotriene C4, and two products, leukotriene A4 and glutathione....

: S-ribosylhomocysteine lyase

S-ribosylhomocysteine lyase

In enzymology, a S-ribosylhomocysteine lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, S--L-homocysteine, and two products, L-homocysteine and -4,5-dihydroxypentan-2,3-dione....

: S-(hydroxymethyl)glutathione synthase

S-(hydroxymethyl)glutathione synthase

In enzymology, a S-glutathione synthase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, S-glutathione, and two products, glutathione and formaldehyde....

: 2-hydroxypropyl-CoM lyase

EC 4.5: Carbon-Halide Lyases

: DDT-dehydrochlorinase

DDT-dehydrochlorinase

In enzymology, a DDT-dehydrochlorinase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 1,1,1-trichloro-2,2-bisethane, and two products, 1,1-dichloro-2,2-bisethylene and chloride....

: 3-chloro-D-alanine dehydrochlorinase

3-chloro-D-alanine dehydrochlorinase

In enzymology, a 3-chloro-D-alanine dehydrochlorinase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-chloro-D-alanine and H2O, whereas its 3 products are pyruvate, chloride, and NH3....

: dichloromethane dehalogenase

Dichloromethane dehalogenase

Dichloromethane dehalogenase is a lyase enzyme which generates formaldehyde.It is classified under ....

: L-2-amino-4-chloropent-4-enoate dehydrochlorinase

L-2-amino-4-chloropent-4-enoate dehydrochlorinase

In enzymology, a L-2-amino-4-chloropent-4-enoate dehydrochlorinase , an enzyme, catalyzes the chemical reaction.Thus, the two substrates of this enzyme are L-2-amino-4-chloropent-4-enoate and H2O, whereas its 3 products are 2-oxopent-4-enoate, chloride, and NH3.This enzyme belongs to the family of...

: S-carboxymethylcysteine synthase

S-carboxymethylcysteine synthase

In enzymology, a S-carboxymethylcysteine synthase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are 3-chloro-L-alanine and thioglycolate, whereas its two products are S-carboxymethyl-L-cysteine and chloride....

EC 4.6: Phosphorus-Oxygen Lyases

: adenylate cyclase

Adenylate cyclase

Adenylate cyclase is part of the G protein signalling cascade, which transmits chemical signals from outside the cell across the membrane to the inside of the cell ....

: guanylate cyclase

Guanylate cyclase

-Reaction:Guanylate cyclase catalyzes the reaction of guanosine triphosphate to 3',5'-cyclic guanosine monophosphate and pyrophosphate:-Types:...

: now EC 4.2.3.4: now EC 4.2.3.5: now EC 4.2.3.7: cytidylate cyclase

Cytidylate cyclase

In enzymology, a cytidylate cyclase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, CTP, and two products, 3',5'-cyclic CMP and diphosphate....

: now EC 4.2.3.8: now EC 4.2.3.10: now EC 4.2.3.11: now EC 4.2.3.12: now EC 4.2.3.13: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

In enzymology, a 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase is an enzyme is a lyase which participates in biosynthesis of steroids. It catalyzes the chemical reaction:...

: phosphatidylinositol diacylglycerol-lyase

Phosphatidylinositol diacylglycerol-lyase

In enzymology, a phosphatidylinositol diacylglycerol-lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 1-phosphatidyl-1D-myo-inositol, and two products, 1D-myo-inositol 1,2-cyclic phosphate and 1,2-diacyl-sn-glycerol.This enzyme belongs to the family of...

: glycosylphosphatidylinositol diacylglycerol-lyase

Glycosylphosphatidylinositol diacylglycerol-lyase

In enzymology, a glycosylphosphatidylinositol diacylglycerol-lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, 6--1-phosphatidyl-1D-myo-inositol, and two products, 6--1D-myo-inositol 1,2-cyclic phosphate and 1,2-diacyl-sn-glycerol.This enzyme belongs to...

: FAD-AMP lyase (cyclizing)

FAD-AMP lyase (cyclizing)

In enzymology, a FAD-AMP lyase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, FAD, and two products, AMP and riboflavin cyclic-4',5'-phosphate....

EC 4.99: Other Lyases

: ferrochelatase

Ferrochelatase

Ferrochelatase is an enzyme that catalyses the terminal step in the biosynthesis of heme, converting protoporphyrin IX into heme. It catalyses the reaction:A ferrochelatase enzyme consists of 497 amino acid residues with a m.w...

: alkylmercury lyase

Alkylmercury lyase

In enzymology, an alkylmercury lyase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are alkylmercury and H+, whereas its two products are alkane and Hg2+....

: sirohydrochlorin cobaltochelatase

Sirohydrochlorin cobaltochelatase

In enzymology, a sirohydrochlorin cobaltochelatase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are cobalt-sirohydrochlorin and H+, whereas its two products are sirohydrochlorin and Co2+....

: sirohydrochlorin ferrochelatase

Sirohydrochlorin ferrochelatase

In enzymology, a sirohydrochlorin ferrochelatase is an enzyme that catalyzes the chemical reactionThus, the two substrates of this enzyme are siroheme and H+, whereas its two products are sirohydrochlorin and Fe2+....

: aliphatic aldoxime dehydratase

Aliphatic aldoxime dehydratase

In enzymology, an aliphatic aldoxime dehydratase is an enzyme that catalyzes the chemical reactionHence, this enzyme has one substrate, aliphatic aldoxime, and two products, aliphatic nitrile and H2O....

: indoleacetaldoxime dehydratase

Indoleacetaldoxime dehydratase

In enzymology, an indoleacetaldoxime dehydratase is an enzyme that catalyzes the chemical reactionacetaldehyde oxime \rightleftharpoons acetonitrile + H2O...

: phenylacetaldoxime dehydratase

Phenylacetaldoxime dehydratase

In enzymology, a phenylacetaldoxime dehydratase is an enzyme that catalyzes the chemical reaction-phenylacetaldehyde oxime \rightleftharpoons phenylacetonitrile + H2O...