Malonyl-CoA decarboxylase
Encyclopedia
Malonyl-CoA decarboxylase is an enzyme associated with Malonyl-CoA decarboxylase deficiency
.
It catalyzes the conversion of malonyl-CoA
into acetyl-CoA
and carbon dioxide
.
To some degree, it reverses the action of Acetyl-CoA carboxylase
.
Malonyl-CoA decarboxylase deficiency
Malonyl-CoA decarboxylase deficiency , or Malonic aciduria is an autosomal recessive metabolic disorder caused by a genetic mutation which disrupts the activity of Malonyl-Coa decarboxylase...
.
It catalyzes the conversion of malonyl-CoA
Malonyl-CoA
Malonyl-CoA is a coenzyme A derivative.-Functions:It plays a key role in chain elongation in fatty acid biosynthesis and polyketide biosynthesis....
into acetyl-CoA
Acetyl-CoA
Acetyl coenzyme A or acetyl-CoA is an important molecule in metabolism, used in many biochemical reactions. Its main function is to convey the carbon atoms within the acetyl group to the citric acid cycle to be oxidized for energy production. In chemical structure, acetyl-CoA is the thioester...
and carbon dioxide
Carbon dioxide
Carbon dioxide is a naturally occurring chemical compound composed of two oxygen atoms covalently bonded to a single carbon atom...
.
To some degree, it reverses the action of Acetyl-CoA carboxylase
Acetyl-CoA carboxylase
Acetyl-CoA carboxylase is a biotin-dependent enzyme that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase and carboxyltransferase...
.