Roman–Parthian Wars
Encyclopedia
The Roman–Parthian Wars (66 BC – 217 AD) were a series of conflicts between the Parthian Empire
Parthian Empire
The Parthian Empire , also known as the Arsacid Empire , was a major Iranian political and cultural power in ancient Persia...

 and the Romans
Ancient Rome
Ancient Rome was a thriving civilization that grew on the Italian Peninsula as early as the 8th century BC. Located along the Mediterranean Sea and centered on the city of Rome, it expanded to one of the largest empires in the ancient world....

. It was the first series of conflicts in what would be 719 years of Roman–Persian Wars.

Early incursions by the Roman Republic
Roman Republic
The Roman Republic was the period of the ancient Roman civilization where the government operated as a republic. It began with the overthrow of the Roman monarchy, traditionally dated around 508 BC, and its replacement by a government headed by two consuls, elected annually by the citizens and...

 against Parthia were repulsed, notably at the Battle of Carrhae
Battle of Carrhae
The Battle of Carrhae, fought in 53 BC near the town of Carrhae, was a major battle between the Parthian Empire and the Roman Republic. The Parthian Spahbod Surena decisively defeated a Roman invasion force led by Marcus Licinius Crassus...

 (53 BC). During the Roman Liberators' civil war
Liberators' civil war
The Liberators' civil war was started by the Second Triumvirate to avenge Julius Caesar's murder. The war was fought by the forces of Mark Antony and Octavian against the forces of Caesar's assassins Marcus Junius Brutus and Gaius Cassius Longinus in 42 BC.-Prelude:After the murder of Caesar,...

 of the 1st Century AD, the Parthians actively supported Brutus
Marcus Junius Brutus
Marcus Junius Brutus , often referred to as Brutus, was a politician of the late Roman Republic. After being adopted by his uncle he used the name Quintus Servilius Caepio Brutus, but eventually returned to using his original name...

 and Cassius, invading Syria, and gaining territories in the Levant. However, the conclusion of the second Roman civil war
Roman civil wars
There were several Roman civil wars, especially during the late Republic. The most famous of these are the war in the 40s BC between Julius Caesar and the optimate faction of the senatorial elite initially led by Pompey and the subsequent war between Caesar's successors, Octavian and Mark Antony in...

 brought a revival of Roman strength in Western Asia.

In 113 AD the Roman Emperor Trajan
Trajan
Trajan , was Roman Emperor from 98 to 117 AD. Born into a non-patrician family in the province of Hispania Baetica, in Spain Trajan rose to prominence during the reign of emperor Domitian. Serving as a legatus legionis in Hispania Tarraconensis, in Spain, in 89 Trajan supported the emperor against...

 made eastern conquests and the defeat of Parthia a strategic priority, and successfully overran the Parthian capital, Ctesiphon
Ctesiphon
Ctesiphon, the imperial capital of the Parthian Arsacids and of the Persian Sassanids, was one of the great cities of ancient Mesopotamia.The ruins of the city are located on the east bank of the Tigris, across the river from the Hellenistic city of Seleucia...

, installing Parthamaspates of Parthia
Parthamaspates of Parthia
Parthamaspates, Roman client king of Parthia and later of Osroene, was the son of the Parthian emperor Osroes I.After spending much of his life in Roman exile, he accompanied the Roman Emperor Trajan on the latter's campaign to conquer Parthia...

 as a client ruler. Hadrian
Hadrian
Hadrian , was Roman Emperor from 117 to 138. He is best known for building Hadrian's Wall, which marked the northern limit of Roman Britain. In Rome, he re-built the Pantheon and constructed the Temple of Venus and Roma. In addition to being emperor, Hadrian was a humanist and was philhellene in...

, Trajan's successor, reversed his predecessor's policy, intending to re-establish the Euphrates
Euphrates
The Euphrates is the longest and one of the most historically important rivers of Western Asia. Together with the Tigris, it is one of the two defining rivers of Mesopotamia...

 as the limit of Roman control. However, in the second centry AD, war over Armenia broke out again in 161 AD, when Vologases I
Vologases IV of Parthia
Vologases IV of Parthia ruled the Parthian Empire from 147 to 191. The son of Mithridates IV of Parthia , he united the two halves of the empire which had been split between his father and Vologases III of Parthia...

 defeated the Romans there. A Roman counter-attack under Statius Priscus defeated the Parthians in Armenia and installed a favored candidate on the Armenian throne, and an invasion of Mesopotamia culminated in the sack of Ctesiphon in 165 AD.

In 195 AD another Roman invasion of Mesopotamia began under the Emperor Septimius Severus
Septimius Severus
Septimius Severus , also known as Severus, was Roman Emperor from 193 to 211. Severus was born in Leptis Magna in the province of Africa. As a young man he advanced through the customary succession of offices under the reigns of Marcus Aurelius and Commodus. Severus seized power after the death of...

, who occupied Seleucia and Babylon
Babylon
Babylon was an Akkadian city-state of ancient Mesopotamia, the remains of which are found in present-day Al Hillah, Babil Province, Iraq, about 85 kilometers south of Baghdad...

, and then sacked Ctesiphon yet again in 197 AD. Parthia ultimately fell not to the Romans, but to the Sassanids under Ardashir I
Ardashir I
Ardashir I was the founder of the Sassanid Empire, was ruler of Istakhr , subsequently Fars Province , and finally "King of Kings of Sassanid Empire " with the overthrow of the Parthian Empire...

, who entered Ctesiphon
Ctesiphon
Ctesiphon, the imperial capital of the Parthian Arsacids and of the Persian Sassanids, was one of the great cities of ancient Mesopotamia.The ruins of the city are located on the east bank of the Tigris, across the river from the Hellenistic city of Seleucia...

 in 226
226
Year 226 was a common year starting on Sunday of the Julian calendar. At the time, it was known as the Year of the Consulship of Severus and Marcellus...

. Under Ardashir and his successors, Persian-Roman conflict continued between the Sassanid Empire
Sassanid Empire
The Sassanid Empire , known to its inhabitants as Ērānshahr and Ērān in Middle Persian and resulting in the New Persian terms Iranshahr and Iran , was the last pre-Islamic Persian Empire, ruled by the Sasanian Dynasty from 224 to 651...

 and Rome.

Parthia's western ambitions

After triumphing in the Seleucid–Parthian wars
Seleucid–Parthian wars
The Seleucid–Parthian wars were a series of conflicts between the Seleucid Empire and Parthia which resulted in the ultimate expulsion of the Seleucids from Persia and the establishment of the Parthian Empire...

 and annexing large amounts of Seleucid Empire the Parthians began to look west for territory to expand into. Parthian enterprise in the West
Western world
The Western world, also known as the West and the Occident , is a term referring to the countries of Western Europe , the countries of the Americas, as well all countries of Northern and Central Europe, Australia and New Zealand...

 began in the time of Mithridates I
Mithridates I of Parthia
Mithridates or Mithradates I was the "Great King" of Parthia from ca. 171 BC - 138 BC, succeeding his brother Phraates I. His father was King Phriapatius of Parthia, who died ca. 176 BC). Mithridates I made Parthia into a major political power by expanding the empire to the east, south, and west...

; during his reign, the Arsacids succeeded in extending their rule into Armenia
Armenia
Armenia , officially the Republic of Armenia , is a landlocked mountainous country in the Caucasus region of Eurasia...

 and Mesopotamia
Mesopotamia
Mesopotamia is a toponym for the area of the Tigris–Euphrates river system, largely corresponding to modern-day Iraq, northeastern Syria, southeastern Turkey and southwestern Iran.Widely considered to be the cradle of civilization, Bronze Age Mesopotamia included Sumer and the...

. This was the beginning of an "international role" for the Parthian empire, a phase that also entailed contacts with Rome. Mithridates II
Mithridates II of Parthia
Mithridates II the Great was king of Parthian Empire from 123 to 88 BC. His name invokes the protection of Mithra. He adopted the title Epiphanes, "god manifest" and introduced new designs on his extensive coinage....

 conducted unsuccessful negotiations with Sulla for a Roman–Parthian alliance (c. 105 BC).

After 90 BC the Parthian power was diminished by dynastic feuds, while at the same time, Roman power in Anatolia
Anatolia
Anatolia is a geographic and historical term denoting the westernmost protrusion of Asia, comprising the majority of the Republic of Turkey...

 collapsed. Roman–Parthian contact was restored when Lucullus invaded Southern Armenia
Roman Armenia
From the end of the 1st century BC onwards, Armenia was, in part or whole, subject to the Roman Empire and its successor, the East Roman or Byzantine Empire...

 and defeated Tigranes
Tigranes the Great
Tigranes the Great was emperor of Armenia under whom the country became, for a short time, the strongest state east of the Roman Republic. He was a member of the Artaxiad Royal House...

 in 69 BC, however, again no definite agreement was made.

Roman Republic vs Parthia

When Pompey
Pompey
Gnaeus Pompeius Magnus, also known as Pompey or Pompey the Great , was a military and political leader of the late Roman Republic...

 took charge of the war in the East, he re-opened negotiations with Phraates III
Phraates III of Parthia
King Phraates III of Parthia succeeded his father Sanatruces and ruled the Parthian Empire from 70 to 57 BC. He was called "the God" because of his coins, that were ideal for sailors because they were polished with gold dust, so that people from other countries considered their value higher than...

; they came to an agreement and Roman–Parthian troops invaded Armenia
Armenia
Armenia , officially the Republic of Armenia , is a landlocked mountainous country in the Caucasus region of Eurasia...

 in 66/65 BC, but soon a dispute arose over Euphrates
Euphrates
The Euphrates is the longest and one of the most historically important rivers of Western Asia. Together with the Tigris, it is one of the two defining rivers of Mesopotamia...

 boundary between Rome and Parthia. Pompey refused to recognize the title of "King of Kings" for Phraates, and offered arbritation between Tigranes and the Parthian king over Corduene
Corduene
Corduene was an ancient region located in northern Mesopotamia and modern day Kurdish inhabited south east Turkey. It was a province of the Greater Armenia. It was referred to by the Greeks as Karduchia and by both the Greeks and Romans as Corduene...

. Finally, Phraates asserted his control over Mesopotamia
Mesopotamia
Mesopotamia is a toponym for the area of the Tigris–Euphrates river system, largely corresponding to modern-day Iraq, northeastern Syria, southeastern Turkey and southwestern Iran.Widely considered to be the cradle of civilization, Bronze Age Mesopotamia included Sumer and the...

, except for the western district of Osroene
Osroene
Osroene, also spelled Osrohene and Osrhoene and sometimes known by the name of its capital city, Edessa , was a historic Syriac kingdom located in Mesopotamia, which enjoyed semi-autonomy to complete independence from the years of 132 BC to AD 244.It was a Syriac-speaking kingdom.Osroene, or...

, which became a Roman dependency.

In 53 BC, Crassus
Marcus Licinius Crassus
Marcus Licinius Crassus was a Roman general and politician who commanded the right wing of Sulla's army at the Battle of the Colline Gate, suppressed the slave revolt led by Spartacus, provided political and financial support to Julius Caesar and entered into the political alliance known as the...

 led an invasion of Mesopotamia, with catastrophic results; at the Battle of Carrhae
Battle of Carrhae
The Battle of Carrhae, fought in 53 BC near the town of Carrhae, was a major battle between the Parthian Empire and the Roman Republic. The Parthian Spahbod Surena decisively defeated a Roman invasion force led by Marcus Licinius Crassus...

, the worst Roman defeat since the Battle of Cannae
Battle of Cannae
The Battle of Cannae was a major battle of the Second Punic War, which took place on August 2, 216 BC near the town of Cannae in Apulia in southeast Italy. The army of Carthage under Hannibal decisively defeated a numerically superior army of the Roman Republic under command of the consuls Lucius...

, Crassus and his son, Publius
Publius Licinius Crassus
Publius Licinius Crassus is the name of several Romans of the Middle and Late Republic, some with the additional cognomen Dives.-3rd century BC:...

, were defeated and killed by a Parthian army under General Surena. The bulk of his force killed or captured; of 42,000 men, about half died, a quarter made it back to Syria
Syria (Roman province)
Syria was a Roman province, annexed in 64 BC by Pompey, as a consequence of his military presence after pursuing victory in the Third Mithridatic War. It remained under Roman, and subsequently Byzantine, rule for seven centuries, until 637 when it fell to the Islamic conquests.- Principate :The...

, and the remainder became prisoners of war. The following year, the Parthians with raids into Syria, and in 51 BC mounted a major invasion led by the crown prince Pacorus
Pacorus I of Parthia
Pacorus I of Parthia was the son of king Orodes II and queen Laodice of the Parthian Empire. It is possible that he was co-ruler with his father for at least part of his father's reign...

 and the general Osaces, but their army was caught in an ambush near Antigonea
Antigonia (Syria)
Antigonia also transliterated as Antigonea and Antigoneia was a Hellenistic city in Seleucis, Syria , on the Orontes, founded by Antigonus I in 307 BC, and intended to be the capital of his empire; the site is approximately 7 km northeast of Antakya, Hatay Province, Turkey...

 by the Romans under Cassius
Gaius Cassius Longinus
Gaius Cassius Longinus was a Roman senator, a leading instigator of the plot to kill Julius Caesar, and the brother in-law of Marcus Junius Brutus.-Early life:...

 and Osaces was killed.

During Caesar's civil war
Caesar's civil war
The Great Roman Civil War , also known as Caesar's Civil War, was one of the last politico-military conflicts in the Roman Republic before the establishment of the Roman Empire...

 the Parthians made no move, but maintained relations with Pompey. After his defeat and death, a force under Pacorus came to the aid of the Pompeian general Caecilius Bassus, who was besieged at Apamea
Apamea (Syria)
Apamea was a treasure city and stud-depot of the Seleucid kings, was capital of Apamene, on the right bank of the Orontes River. . Its site is found about to the northwest of Hama, Syria, overlooking the Ghab valley...

 Valley by the Caesarian forces. With the civil war over, Julius Caesar
Julius Caesar
Gaius Julius Caesar was a Roman general and statesman and a distinguished writer of Latin prose. He played a critical role in the gradual transformation of the Roman Republic into the Roman Empire....

 elaborated plans for a campaign against Parthia, but his assassination averted the war. During the ensuing Liberators' civil war
Liberators' civil war
The Liberators' civil war was started by the Second Triumvirate to avenge Julius Caesar's murder. The war was fought by the forces of Mark Antony and Octavian against the forces of Caesar's assassins Marcus Junius Brutus and Gaius Cassius Longinus in 42 BC.-Prelude:After the murder of Caesar,...

, the Parthians actively supported Brutus
Marcus Junius Brutus
Marcus Junius Brutus , often referred to as Brutus, was a politician of the late Roman Republic. After being adopted by his uncle he used the name Quintus Servilius Caepio Brutus, but eventually returned to using his original name...

 and Cassius, sending a contingent which fought with them at the Battle of Philippi
Battle of Philippi
The Battle of Philippi was the final battle in the Wars of the Second Triumvirate between the forces of Mark Antony and Octavian and the forces of Julius Caesar's assassins Marcus Junius Brutus and Gaius Cassius Longinus in 42 BC, at Philippi in Macedonia...

 in 42 B.
After that defeat, the Parthians under Pacorus invaded Roman territory in 40 BC in conjunction with Quintus Labienus
Quintus Labienus
Quintus Labienus , the son of Titus Labienus, was a Roman republican general, later in the service of Parthia.After Julius Caesar was murdered in 44 BC, Labienus took the side of Brutus and Cassius, the latter whom he served in the capacity of an ambassador to the Parthians...

, a Roman erstwhile supporter of Brutus and Cassius. They swiftly overran Syria, and defeated Roman forces in the province; all the cities of the coast, with the exception of Tyre admitted the Parthians. Pacorus then advanced into Hasmonean
Hasmonean
The Hasmonean dynasty , was the ruling dynasty of Judea and surrounding regions during classical antiquity. Between c. 140 and c. 116 BCE, the dynasty ruled semi-autonomously from the Seleucids in the region of Judea...

 Judea
Judea
Judea or Judæa was the name of the mountainous southern part of the historic Land of Israel from the 8th century BCE to the 2nd century CE, when Roman Judea was renamed Syria Palaestina following the Jewish Bar Kokhba revolt.-Etymology:The...

, overthrowing the Roman client Hyrcanus II
Hyrcanus II
Hyrcanus II, a member of the Hasmonean dynasty, was the Jewish High Priest and King of Judea in the 1st century BC.-Accession:Hyrcanus was the eldest son of Alexander Jannaeus, King and High Priest, and Alexandra Salome...

 and installing his nephew Antigonus
Antigonus the Hasmonean
Antigonus II Mattathias was the last Hasmonean king of Judea. He was the son of King Aristobulus II of Judea...

 (40–37 BC) in his place. For a moment, the whole of the Roman East seemed to be either in Parthian hands or on the point of capture. The conclusion of the second Roman civil war
Roman civil wars
There were several Roman civil wars, especially during the late Republic. The most famous of these are the war in the 40s BC between Julius Caesar and the optimate faction of the senatorial elite initially led by Pompey and the subsequent war between Caesar's successors, Octavian and Mark Antony in...

 was soon to bring about a revival of Roman strength in Western Asia.

Meanwhile Mark Antony
Mark Antony
Marcus Antonius , known in English as Mark Antony, was a Roman politician and general. As a military commander and administrator, he was an important supporter and loyal friend of his mother's cousin Julius Caesar...

 had already sent Ventidius
Publius Ventidius Bassus
Publius Ventidius Bassus, or in full, Publius Ventidius Publii filius Bassus, "Publius Ventidius, Publius's son, Bassus" was a Roman general and one of Julius Caesar's protégés...

 to oppose Labienus who had invaded Anatolia. Soon Labienius was driven back to Syria by Roman forces, and, though his Parthians allies came to his support, he was defeated, taken prisoner and then put to death. After suffering a further defeat near the Syrian Gates
Syrian Gates
The Belen Pass , also known as the Syrian Gates, is a mountain pass located in the Belen District of Hatay Province in south-central Turkey...

, the Parthians withdrew from Syria. They returned in 38 BC, but were decisively defeated by Ventidius and Pacorus was killed. In Judea, Antigonus was ousted with Roman help by the Idumean Herod
Herod the Great
Herod , also known as Herod the Great , was a Roman client king of Judea. His epithet of "the Great" is widely disputed as he is described as "a madman who murdered his own family and a great many rabbis." He is also known for his colossal building projects in Jerusalem and elsewhere, including his...

 in 37 BC.

With Roman control of Syria
Syria (Roman province)
Syria was a Roman province, annexed in 64 BC by Pompey, as a consequence of his military presence after pursuing victory in the Third Mithridatic War. It remained under Roman, and subsequently Byzantine, rule for seven centuries, until 637 when it fell to the Islamic conquests.- Principate :The...

 and Judaea
Iudaea Province
Judaea or Iudaea are terms used by historians to refer to the Roman province that extended over parts of the former regions of the Hasmonean and Herodian kingdoms of Israel...

 restored, Mark Antony led a huge army into Azerbaijan
Azerbaijan
Azerbaijan , officially the Republic of Azerbaijan is the largest country in the Caucasus region of Eurasia. Located at the crossroads of Western Asia and Eastern Europe, it is bounded by the Caspian Sea to the east, Russia to the north, Georgia to the northwest, Armenia to the west, and Iran to...

, but his siege train and its escort were isolated and wiped out, while his Armenian allies
Armenians
Armenian people or Armenians are a nation and ethnic group native to the Armenian Highland.The largest concentration is in Armenia having a nearly-homogeneous population with 97.9% or 3,145,354 being ethnic Armenian....

 deserted. Failing to make progress against Parthian positions, the Romans withdrew with heavy casualties. In 33 BC Antony was again in Armenia, contracting an alliance with the Median
Atropatene
Atropatene was an ancient kingdom established and ruled under local ethnic Iranian dynasts first with "Darius" of Persia and later "Alexander" of Macedonia, starting in the 4th century BC and includes the territory of modern-day Iranian Azarbaijan and Iranian Kurdistan. Its capital was Gazaca...

 king against both Octavian, and the Parthians, but other preoccupations obliged him to withdraw, and the whole region passed under Parthian control.

Inconclusive wars

Under the threat of an impending war between the two powers, Gaius Caesar
Gaius Caesar
Gaius Julius Caesar , most commonly known as Gaius Caesar or Caius Caesar, was the oldest son of Marcus Vipsanius Agrippa and Julia the Elder...

 and Phraataces
Phraates V of Parthia
Phraates V of Persia, known by the diminutive Phraataces , ruled the Iranian Parthian Empire from 2 BC to AD 4. He was the younger son of Phraates IV of Parthia and the Musa of Parthia", with whom he is associated on his coins. Under Phraates V a war threatened to break out with Rome about the...

 worked out a rough compromise under the two powers in 1 AD. According to the agreement, Parthia undertook to withdraw its forces from Armenia, and to recognize a de facto Roman protectorate over the country. Nonetheless, Roman-Persian rivalry over control and influence in Armenia continued unabated for the next several decades.

The decision of the Parthian king Artabanus II
Artabanus II of Parthia
Artabanus II of Parthia ruled the Parthian Empire from about AD 10 to 38. He was the son of a princess of the Arsacid Dynasty, who lived in the East among the Dahan nomads...

 to place his son, Arsaces, on the vacant Armenian throne triggered a war with Rome in 36 AD. Artabanus reached an understanding with the Roman general, Lucius Vitellius
Lucius Vitellius
Lucius Vitellius the Elder was the youngest of four sons of quaestor Publius Vitellius and the only one that did not die through politics. Under Emperor Tiberius, he was Consul in 34 and Governor of Syria in 35. He deposed Pontius Pilate in 36 after complaints from the people in Samaria...

, renunciating Parthian claims to a Parhian sphere of influence in Armenia. A new crisis was triggered in 58 AD, when the Romans invaded Armenia after the Parthian king Vologases I forcibly installed his brother Tiridates
Tiridates I of Armenia
Tiridates I was King of Armenia beginning in AD 53 and the founder of the Arshakuni Dynasty, the Armenian line of the Arsacid Dynasty. The dates of his birth and death are unknown. His early reign was marked by a brief interruption towards the end of the year 54 and a much longer one from 58...

 on the throne there. Roman forces under Corbulo
Gnaeus Domitius Corbulo
Gnaeus Domitius Corbulo was a Roman general and a brother-in-law of the emperor Caligula.-Descent:Corbulo was born in Italy into a senatorial family...

 overthrew Tiridates and replaced him with a Cappadocian prince. This prompted Parthian retaliation and an inconclusive series of campaigns in Armenia ensued. The war came to an end in 63 AD, when the Romans agreed to allow Tiridates and his descendants to rule Armenia on condition that they received the kingship from the Roman emperor.

Trajan's Parthian War

A new series of wars began in the 2nd century AD, during which the Romans consistently held the upper hand over Parthia. In 113 AD the Roman Emperor Trajan
Trajan
Trajan , was Roman Emperor from 98 to 117 AD. Born into a non-patrician family in the province of Hispania Baetica, in Spain Trajan rose to prominence during the reign of emperor Domitian. Serving as a legatus legionis in Hispania Tarraconensis, in Spain, in 89 Trajan supported the emperor against...

 decided that the moment was ripe to resolve the "eastern question" once and for all time by the decisive defeat of Parthia and the annexation of Armenia; his conquests mark a deliberate change of the Roman Policy towards Parthia, and a shift of emphasis in the "grand strategy" of the empire.

In 114 AD Trajan invaded Armenia, annexed it as a Roman province, and killed Parthamasiris who was placed on the Armenian throne by his brother the king of Parthia, Osroes I
Osroes I of Parthia
Osroes I of Parthia ruled the Parthian Empire c. 109–129. He succeeded his brother Pacorus II. For the whole of his reign he contended with the rival king Vologases III based in the east of Parthia....

. In 115 AD the Roman emperor overran northern Mesopotamia and annexed to Rome as well; its conquest was deemed necessary, since otherwise the Armenian salient could be cut off by the Parthians from the south. The Romans then captured the Parthian capital, Ctesiphon, before sailing downriver to the Persian Gulf
Persian Gulf
The Persian Gulf, in Southwest Asia, is an extension of the Indian Ocean located between Iran and the Arabian Peninsula.The Persian Gulf was the focus of the 1980–1988 Iran-Iraq War, in which each side attacked the other's oil tankers...

. However, in that year revolts erupted in Palestine
Palestine
Palestine is a conventional name, among others, used to describe the geographic region between the Mediterranean Sea and the Jordan River, and various adjoining lands....

, Syria and northern Mesopotamia, while a major Jewish revolt
Kitos War
The Kitos War , translation: Rebellion of the exile) is the name given to the second of the Jewish–Roman wars. Major revolts by diasporic Jews in Cyrene , Cyprus, Mesopotamia and Aegyptus spiraled out of control resulting in a widespread slaughter of Roman citizens and others by the Jewish rebels...

 broke out in Roman territory, severely stretching Roman military resources. Simultaneously, Parthian forces began attacking key Roman positions; at the same time the Roman garrisons at Seleucia
Seleucia
Seleucia was the first capital of the Seleucid Empire, and one of the great cities of antiquity standing in Mesopotamia, on the Tigris River.Seleucia may refer to:...

, Nisibis and Edessa
Edessa, Mesopotamia
Edessa is the Greek name of an Aramaic town in northern Mesopotamia, as refounded by Seleucus I Nicator. For the modern history of the city, see Şanlıurfa.-Names:...

 had been attacked and evicted by the local populaces. Trajan subdued the rebels in Mesopotamia, but having installed the Parthian prince Parthamaspates
Parthamaspates of Parthia
Parthamaspates, Roman client king of Parthia and later of Osroene, was the son of the Parthian emperor Osroes I.After spending much of his life in Roman exile, he accompanied the Roman Emperor Trajan on the latter's campaign to conquer Parthia...

 on the throne there as a client ruler he withdrew his armies, and proceeded to Syria, where he set up his headquarters at Antioch. In 117, before he could reorganize the effort to consolidate Roman control over the Parthian provinces, Trajan died.

Hadrian's policy, and further wars of annexation

Trajan's successor, Hadrian
Hadrian
Hadrian , was Roman Emperor from 117 to 138. He is best known for building Hadrian's Wall, which marked the northern limit of Roman Britain. In Rome, he re-built the Pantheon and constructed the Temple of Venus and Roma. In addition to being emperor, Hadrian was a humanist and was philhellene in...

, promptly reversed his predecessor's policy, which he considered a potential long-term liability for the empire. He decided that it was in Rome's interest to re-establish the Euphrates as the limit of its direct control, and willingly returned to the status quo ante, surrendering the territories of Armenia, Mesopotamia, and Adiabene
Adiabene
Adiabene was an ancient Assyrian independent kingdom in Mesopotamia, with its capital at Arbela...

 back to their previous rulers and client-kings. Once again, at least for another half century, Rome was to avoid active intervention east of the Euphrates.

War over Armenia broke out again in 161 AD, when Vologases I
Vologases IV of Parthia
Vologases IV of Parthia ruled the Parthian Empire from 147 to 191. The son of Mithridates IV of Parthia , he united the two halves of the empire which had been split between his father and Vologases III of Parthia...

 defeated the Romans there, captured Edessa and ravaged Syria. In 163 AD a Roman counter-attack under Statius Priscus defeated the Parthians in Armenia and installed a favored candidate on the Armenian throne. The following year Avidius Cassius
Avidius Cassius
Gaius Avidius Cassius was a Roman general and usurper who briefly ruled Egypt and Syria in 175.-Origins:He was the son of Gaius Avidius Heliodorus, a noted orator who was Prefect of Egypt from 137 to 142 under Hadrian, and wife Junia Cassia Alexandra...

 began an invasion of Mesopotamia, winning battles at Dura-Europos
Dura-Europos
Dura-Europos , also spelled Dura-Europus, was a Hellenistic, Parthian and Roman border city built on an escarpment 90 m above the right bank of the Euphrates river. It is located near the village of Salhiyé, in today's Syria....

 and Seleucia and sacking Ctesiphon in 165 AD. An epidemic, possibly of smallpox, which was sweeping Parthia at the time now spread to the Roman army, leading to their withdrawal.

In 195 AD another Roman invasion of Mesopotamia began under the Emperor Septimius Severus
Septimius Severus
Septimius Severus , also known as Severus, was Roman Emperor from 193 to 211. Severus was born in Leptis Magna in the province of Africa. As a young man he advanced through the customary succession of offices under the reigns of Marcus Aurelius and Commodus. Severus seized power after the death of...

, who occupied Seleucia and Babylon
Babylon
Babylon was an Akkadian city-state of ancient Mesopotamia, the remains of which are found in present-day Al Hillah, Babil Province, Iraq, about 85 kilometers south of Baghdad...

, and then sacked Ctesiphon yet again in 197 AD. These wars led to the Roman acquisition of northern Mesopotamia, as far as the areas around Nisibis and Singara. A final war against the Parthians was launched by the emperor Caracalla
Caracalla
Caracalla , was Roman emperor from 198 to 217. The eldest son of Septimius Severus, he ruled jointly with his younger brother Geta until he murdered the latter in 211...

, who sacked Arbela
Arbil
Arbil / Hewlêr is the fourth largest city in Iraq after Baghdad, Basra and Mosul...

 in 216 AD, but after his assassination his successor Macrinus
Macrinus
Macrinus , was Roman Emperor from 217 to 218. Macrinus was of "Moorish" descent and the first emperor to become so without membership in the senatorial class.-Background and career:...

 was defeated by the Parthians near Nisibis
Battle of Nisibis (217)
The Battle of Nisibis was fought in the summer of 217 between the armies of the Roman Empire under the newly ascended emperor Macrinus and the Parthian army of King Artabanus IV. It lasted for three days, and resulted in a bloody draw, with both sides suffering large casualties...

 and was obliged to make a payment of reparations for the damage done by Caracalla in exchange for peace.

Rise of the Sassanids

Parthia was finally destroyed by Ardashir I
Ardashir I
Ardashir I was the founder of the Sassanid Empire, was ruler of Istakhr , subsequently Fars Province , and finally "King of Kings of Sassanid Empire " with the overthrow of the Parthian Empire...

 when he entered Ctesiphon
Ctesiphon
Ctesiphon, the imperial capital of the Parthian Arsacids and of the Persian Sassanids, was one of the great cities of ancient Mesopotamia.The ruins of the city are located on the east bank of the Tigris, across the river from the Hellenistic city of Seleucia...

 in 226
226
Year 226 was a common year starting on Sunday of the Julian calendar. At the time, it was known as the Year of the Consulship of Severus and Marcellus...

. The Sassanids were more centralized than the Parthian dynasties.
Until the Sassanids
Sassanid Empire
The Sassanid Empire , known to its inhabitants as Ērānshahr and Ērān in Middle Persian and resulting in the New Persian terms Iranshahr and Iran , was the last pre-Islamic Persian Empire, ruled by the Sasanian Dynasty from 224 to 651...

 came to power, the Romans were mostly the aggressors. However, the Sassanids, being Persians, were determined to reconquer lands that the Achaemenid dynasty had once held and now lost. Their nationalistic zeal made them much more aggressive foes of the Romans than the Parthians ever were. For more information, see Byzantine-Sassanid Wars.

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