The Strain
Encyclopedia
The Strain is the first novel of a vampire
Vampire
Vampires are mythological or folkloric beings who subsist by feeding on the life essence of living creatures, regardless of whether they are undead or a living person...

 trilogy, co-authored by Guillermo del Toro
Guillermo del Toro
Guillermo del Toro is a Mexican director, producer, screenwriter, novelist and designer. He is mostly known for his acclaimed films, Blade II, Pan's Labyrinth and the Hellboy film franchise. He is a frequent collaborator with Ron Perlman, Federico Luppi and Doug Jones...

 and Chuck Hogan
Chuck Hogan
Chuck Hogan is an American author. He is the author of Prince of Thieves: A Novel, a work upon which Ben Affleck's Academy Award-nominated film The Town is based on. The work won the 2005 Hammett Prize and was called one of the ten best novels of the year by Stephen King...

.

The book was released on June 2, 2009. The second installment, The Fall, was released on September 21, 2010. The final entry, The Night Eternal, was released on October 25, 2011.

To celebrate the book's release del Toro did signings at Meltdown Comics in Los Angeles
Los Ángeles
Los Ángeles is the capital of the province of Biobío, in the commune of the same name, in Region VIII , in the center-south of Chile. It is located between the Laja and Biobío rivers. The population is 123,445 inhabitants...

 and various Barnes & Noble in New York
New York
New York is a state in the Northeastern region of the United States. It is the nation's third most populous state. New York is bordered by New Jersey and Pennsylvania to the south, and by Connecticut, Massachusetts and Vermont to the east...

.

Plot Introduction

A Boeing 777
Boeing 777
The Boeing 777 is a long-range, wide-body twin-engine jet airliner manufactured by Boeing Commercial Airplanes. It is the world's largest twinjet and is commonly referred to as the "Triple Seven". The aircraft has seating for over 300 passengers and has a range from , depending on model...

 arrives at JFK
John F. Kennedy International Airport
John F. Kennedy International Airport is an international airport located in the borough of Queens in New York City, about southeast of Lower Manhattan. It is the busiest international air passenger gateway to the United States, handling more international traffic than any other airport in North...

 and is on its way across the tarmac, when it suddenly stops dead. All window shades are pulled down. All lights are out. All communication channels have gone quiet. Crews on the ground are lost for answers, but an alert goes out to the CDC
Centers for Disease Control and Prevention
The Centers for Disease Control and Prevention are a United States federal agency under the Department of Health and Human Services headquartered in Druid Hills, unincorporated DeKalb County, Georgia, in Greater Atlanta...

. Dr. Eph Goodweather, head of their Canary project, a rapid-response team that investigates biological threats, gets the call and boards the plane. What he finds makes his blood run cold.

In a pawnshop in Spanish Harlem, a former professor and survivor of the Holocaust
The Holocaust
The Holocaust , also known as the Shoah , was the genocide of approximately six million European Jews and millions of others during World War II, a programme of systematic state-sponsored murder by Nazi...

 named Abraham Setrakian knows something is happening. And he knows the time has come, that a war is brewing.

So begins a battle of mammoth proportions as the vampiric virus that has infected New York
New York City
New York is the most populous city in the United States and the center of the New York Metropolitan Area, one of the most populous metropolitan areas in the world. New York exerts a significant impact upon global commerce, finance, media, art, fashion, research, technology, education, and...

 begins to spill out into the streets. Eph, who is joined by Setrakian and a motley crew of fighters, must now find a way to stop the contagion and save his city - a city that includes his wife and son - before it is too late.

Vampire Biology

The series places special emphasis on the biology of vampires as parasitic
Parasitism
Parasitism is a type of symbiotic relationship between organisms of different species where one organism, the parasite, benefits at the expense of the other, the host. Traditionally parasite referred to organisms with lifestages that needed more than one host . These are now called macroparasites...

 creatures, and the life cycle and physical adaptations of a human-turned-vampire are covered in exhaustive detail. The vector for vampirism is a capillary worm
Parasitic worm
Parasitic worms or helminths are a division of eukaryoticparasites that, unlike external parasites such as lice and fleas, live inside their host. They are worm-like organisms that live and feed off living hosts, receiving nourishment and protection while disrupting their hosts' nutrient...

, which, once introduced into the human host's bloodstream (either through a vampire's feeding or direct invasion by the worm through a wound or orifice), introduces an incurable and fast-acting virus
Virus
A virus is a small infectious agent that can replicate only inside the living cells of organisms. Viruses infect all types of organisms, from animals and plants to bacteria and archaea...

. By manipulating the host's genes
Transduction (genetics)
Transduction is the process by which DNA is transferred from one bacterium to another by a virus. It also refers to the process whereby foreign DNA is introduced into another cell via a viral vector. Transduction does not require cell-to-cell contact , and it is DNAase resistant...

, the virus causes a human to undergo numerous radical physical changes.
Vampire Physicality

The first and most distinct vampire adaptation is the development of a long, retractile proboscis
Proboscis
A proboscis is an elongated appendage from the head of an animal, either a vertebrate or an invertebrate. In simpler terms, a proboscis is the straw-like mouth found in several varieties of species.-Etymology:...

 beneath the host's tongue, which is able to extend up to six feet from the mouth. This "stinger" is both the vampire's feeding and reproductive mechanism, shooting forth to latch onto human prey's throat
Common carotid artery
In human anatomy, the common carotid artery is an artery that supplies the head and neck with oxygenated blood; it divides in the neck to form the external and internal carotid arteries. - Structure :...

 or thigh
Femoral artery
The femoral artery is a general term comprising a few large arteries in the thigh. They begin at the inguinal ligament and end just above the knee at adductor canal or Hunter's canal traversing the extent of the femur bone....

, both draining the victim's blood for nutrition
Hematophagy
Hematophagy is the practice of certain animals of feeding on blood...

 and infecting the human with capillary worms. The vampire's jaw is set at a lower hinge than a human, the mouth gaping like a snake's when the stinger is deployed. As the structure of the stinger is actually modified tissue from the human lungs and throat, vampires are incapable of physical speech.

A vampire's physical appearance is governed mainly by the host body shedding those human traits that are obsolete to its new life cycle. Hair and fingernails are gradually lost, while the external nose and ears atrophy, leaving a fully matured vampire's skin as smooth and featureless as marble. The vampire's complexion is extremely pale between feedings, but appears a flushed red after a recent blood-meal. Eye coloration is a black pupil surrounded by a red sclera
Sclera
The sclera , also known as the white or white of the eye, is the opaque , fibrous, protective, outer layer of the eye containing collagen and elastic fiber. In the development of the embryo, the sclera is derived from the neural crest...

, with a white nictitating membrane
Nictitating membrane
The nictitating membrane is a transparent or translucent third eyelid present in some animals that can be drawn across the eye for protection and to moisten it while maintaining visibility. Some reptiles, birds, and sharks have a full nictitating membrane; in many mammals, there is a small...

 sliding across for protection. The middle fingers of both hands grow and strengthen, and a thick talon
Talon
A talon is a sharp claw of an animal, especially a bird of prey, such as the eagle, hawk, falcon, owl, or buzzard. It may also refer to:Places:* Talon, Nièvre, a commune in the Nièvre département in France...

 develops in place of the lost fingernail. As vampire reproduction is achieved through viral infection of hosts and not through any sexual mechanism, the human genitalia also atrophy, leaving a mature vampire with no discernible gender.

The digestive and circulatory systems of a vampire are simplified and fused, the vampire's interior organs most resembling a series of connected sacs. Nutrition from a blood feeding is transported throughout this system via a thick, viscous white fluid that forms the vampire equivalent of blood. The capillary worms are present in this fluid, swimming throughout the circulatory system and often visible beneath the vampire's thin skin. Like rodents, a vampire is unable to vomit, its suction-based digestive process functioning only one way. All bodily waste is excreted from a single rectal orifice in the form of a pungent ammonia-based spray
Guano
Guano is the excrement of seabirds, cave dwelling bats, and seals. Guano manure is an effective fertilizer due to its high levels of phosphorus and nitrogen and also its lack of odor. It was an important source of nitrates for gunpowder...

; a vampire will excrete for the entire duration of a feeding, purging old food as it consumes new blood.

The vampire's body temperature runs extremely high, at 120 degrees Fahrenheit, and a human is able to feel their ambient heat from several feet away.

Many of the physical changes from human to vampire occur gradually following the initial worm infection, and are accompanied by great pain. A newly "turned" human will lie in a state of suspended animation
Suspended animation
Suspended animation is the slowing of life processes by external means without termination. Breathing, heartbeat, and other involuntary functions may still occur, but they can only be detected by artificial means. Extreme cold can be used to precipitate the slowing of an individual's functions; use...

 for an entire day, rising the next night as a nascent vampire. The stinger is present for the vampire's first foray, in order to facilitate feeding, but other traits (hairlessness, talons on the mid-digit, lack of distinct internal organs) will develop within the first seven nights following infection. The vampire's mental state will also be confused at first, and its movements will be clumsy and awkward. As it matures, however, the vampire will become supremely agile, able to leap great distances and climb sheer surfaces with the aid of its talons. Full maturity, physically and mentally, occurs within the first thirty nights.

In spite of the vampire's morbid biology stripping legend of most of its romance, the most famously admired trait of the undead remains intact: immortality
Immortality
Immortality is the ability to live forever. It is unknown whether human physical immortality is an achievable condition. Biological forms have inherent limitations which may or may not be able to be overcome through medical interventions or engineering...

. Unless slain by violence or sunlight, a vampire's parasitic body structure will neither fade nor weaken with the passage of time, giving them an effectively endless "life"-span. Even in those cases where the host body is damaged beyond repair, a vampire of sufficient power can transfer their consciousness (via a torrential capillary worm transfer) from one human form to another.
Vampire Senses

The sensory apparatus of the vampire is highly adapted for their nocturnal life cycle. Color vision is replaced with the ability to sense heat signatures
Infrared sensing in snakes
The ability to sense infrared thermal radiation evolved independently in several different families of snakes. Essentially, it allows these animals to “see” radiant heat at wavelengths between 5 and 30 μm to a degree of accuracy such that a blind rattlesnake can target vulnerable body parts of the...

, and the world is perceived in a monochrome brightened by sources of warmth (such as human prey). Hearing is greatly enhanced, in spite of the loss of external ears.

The vampires' greatest sensory asset, however, is the "hive mind"
Group mind (science fiction)
A group mind, hive mind or group ego in science fiction is a single consciousness occupying many bodies. Its use in literature goes back at least as far as Olaf Stapledon's science fiction novel Last and First Men ....

 that all new vampires share with the Ancient that propagated them. Each vampire, through some undefined telepathic link, is able to send and receive thought and sensory information to and from their Ancient progenitor. In this manner, the Ancient vampires direct the actions of their individual spawn through mental communication, regardless of distance. Perhaps akin to its radiation shielding properties, the element lead
Lead
Lead is a main-group element in the carbon group with the symbol Pb and atomic number 82. Lead is a soft, malleable poor metal. It is also counted as one of the heavy metals. Metallic lead has a bluish-white color after being freshly cut, but it soon tarnishes to a dull grayish color when exposed...

 has the effect of blocking this mental connection.

In spite of their biological inability to speak, vampires can communicate with humans through telepathy
Telepathy
Telepathy , is the induction of mental states from one mind to another. The term was coined in 1882 by the classical scholar Fredric W. H. Myers, a founder of the Society for Psychical Research, and has remained more popular than the more-correct expression thought-transference...

, transmitting thoughts directly into a person's internal monologue
Internal monologue
Internal monologue, also known as inner voice, internal speech, or verbal stream of consciousness is thinking in words. It also refers to the semi-constant internal monologue one has with oneself at a conscious or semi-conscious level....

. Those vampires seeking to pose as human can train themselves to move their lips in a pantomime of speech, but the actual communication is still via thought-transference.

An Ancient vampire is also able to use this telepathic ability as a weapon; known as the "murmur", this mental shock-wave has the ability to completely overwhelm the minds of surrounding human beings, rendering them unconscious.

Vampires also experience an overwhelming compulsion to infect family members and those they cared about as humans (their "dear ones"). They possess a unique ability to locate such targets, this sense being likened to a pigeon's homing instinct.
Vampire Weaknesses

Many of the traditional vampire "weaknesses" of common folklore remain effective, although their potency is explained in terms of specific effects on vampire biology.

Sunlight
Sunlight
Sunlight, in the broad sense, is the total frequency spectrum of electromagnetic radiation given off by the Sun. On Earth, sunlight is filtered through the Earth's atmosphere, and solar radiation is obvious as daylight when the Sun is above the horizon.When the direct solar radiation is not blocked...

 is the vampire's ultimate destroyer, specifically ultraviolet light in the UVC range. This is due to the germicidal properties of the wavelength
Ultraviolet germicidal irradiation
Ultraviolet germicidal irradiation is a sterilization method that uses ultraviolet light at sufficiently short wavelength to kill microorganisms. It is used in a variety of applications, such as food, air and water purification. UV has been a known mutagen at the cellular level for more than...

, as it breaks down the virus-laden tissues of the vampire's body. A localized source of UVC light, such as a fluorescent lamp, can be used to repel a vampire, much as a burning torch can repel an animal. Complete exposure, either to direct sunlight or a powerful UVC source, will result in complete desiccation
Desiccation
Desiccation is the state of extreme dryness, or the process of extreme drying. A desiccant is a hygroscopic substance that induces or sustains such a state in its local vicinity in a moderately sealed container.-Science:...

 of the vampire's body, leaving behind nothing but ashes.

Silver
Silver
Silver is a metallic chemical element with the chemical symbol Ag and atomic number 47. A soft, white, lustrous transition metal, it has the highest electrical conductivity of any element and the highest thermal conductivity of any metal...

, whether in the form of a metal weapon or even a fine chemical mist, can also wound or kill a vampire. Much like sunlight, this is due to the disinfecting properties of the element damaging the vampire's viral biology. While conventional weapons (lead bullets, steel blades) can cause physical damage, they will not repel a vampire. Silver causes vampires both debilitating pain and a certain amount of fear, and binding a vampire in silver will completely incapacitate them.

Severing the spinal column through any method is another effective way to destroy a vampire. While the vampire's simplified internal organ structure makes them difficult to harm with attacks to the body, decapitation
Decapitation
Decapitation is the separation of the head from the body. Beheading typically refers to the act of intentional decapitation, e.g., as a means of murder or execution; it may be accomplished, for example, with an axe, sword, knife, wire, or by other more sophisticated means such as a guillotine...

 will result in the vampire's death.

Although there appears to be no biological imperative behind it, vampires cannot cross running water. This is alluded to as having something to do with the origin of the Ancients, but no further explanation is given. This aversion to water can be overcome, however, if the vampire is assisted (or "invited") by a human.

Traditional religious protections against vampires, such as a crucifix
Crucifix
A crucifix is an independent image of Jesus on the cross with a representation of Jesus' body, referred to in English as the corpus , as distinct from a cross with no body....

 or holy water
Holy water
Holy water is water that, in Catholicism, Anglicanism, Eastern Orthodoxy, Lutheranism, Oriental Orthodoxy, and some other churches, has been sanctified by a priest for the purpose of baptism, the blessing of persons, places, and objects; or as a means of repelling evil.The use for baptism and...

, display no practical effect. The prevalence of this lore is explained as having been the product of Bram Stoker
Bram Stoker
Abraham "Bram" Stoker was an Irish novelist and short story writer, best known today for his 1897 Gothic novel Dracula...

's "fevered Irish imagination".

Garlic
Garlic
Allium sativum, commonly known as garlic, is a species in the onion genus, Allium. Its close relatives include the onion, shallot, leek, chive, and rakkyo. Dating back over 6,000 years, garlic is native to central Asia, and has long been a staple in the Mediterranean region, as well as a frequent...

, another common folk defense, has no noticeable use in repelling vampires.

Silver-backed mirror
Mirror
A mirror is an object that reflects light or sound in a way that preserves much of its original quality prior to its contact with the mirror. Some mirrors also filter out some wavelengths, while preserving other wavelengths in the reflection...

s, while they will not harm a vampire, will reveal their presence. While vampires do indeed cast a reflection, it is blurred and distorted, akin to an image vibrating at an impossible speed. Modern chrome-backed mirrors, however, will not have this effect, and the vampire will appear normally in such a looking-glass.
Dr. Ephraim Goodweather

Head of the CDC's rapid-response team, the Canary Project, Eph is a newly divorced father attempting to balance the custody battle over his son Zack with his duties as an epidemiologist
Epidemiology
Epidemiology is the study of health-event, health-characteristic, or health-determinant patterns in a population. It is the cornerstone method of public health research, and helps inform policy decisions and evidence-based medicine by identifying risk factors for disease and targets for preventive...

. Along with his fellow Canary member (and love interest) Nora Martinez, he is a first-responder to the Boeing 777 disaster. Unable to reconcile the symptoms of the newly infected airline passengers with standard disease pathology, Eph is convinced of the reality of vampires by Abraham Setrakian. Discredited at the CDC by the vampires' human conspirators, Dr. Goodweather finds himself a fugitive from both the human authorities and the undead. The need to protect his son drives Eph's every action.
Professor Abraham Setrakian

A Romania
Romania
Romania is a country located at the crossroads of Central and Southeastern Europe, on the Lower Danube, within and outside the Carpathian arch, bordering on the Black Sea...

n Jew
Jews
The Jews , also known as the Jewish people, are a nation and ethnoreligious group originating in the Israelites or Hebrews of the Ancient Near East. The Jewish ethnicity, nationality, and religion are strongly interrelated, as Judaism is the traditional faith of the Jewish nation...

 who escaped the Treblinka extermination camp
Treblinka extermination camp
Treblinka was a Nazi extermination camp in occupied Poland during World War II near the village of Treblinka in the modern-day Masovian Voivodeship of Poland. The camp, which was constructed as part of Operation Reinhard, operated between and ,. During this time, approximately 850,000 men, women...

 during the Second World War
World War II
World War II, or the Second World War , was a global conflict lasting from 1939 to 1945, involving most of the world's nations—including all of the great powers—eventually forming two opposing military alliances: the Allies and the Axis...

, Professor Setrakian has been a dedicated (and perhaps fanatic) vampire hunter for over six decades. Wielding a silver sword with hands nearly crippled from his first encounter with the Master, Setrakian is an expert on vampire biology and destruction, and recruits Eph and Nora to his cause. His determination and will are strong, but his weak heart has become an obstacle to his life-long quest.
The Master / Jusef Sardu

One of the Ancients, the seven original vampires, the Master now inhabits the body of Jusef Sardu, a 19th century Polish
Poland
Poland , officially the Republic of Poland , is a country in Central Europe bordered by Germany to the west; the Czech Republic and Slovakia to the south; Ukraine, Belarus and Lithuania to the east; and the Baltic Sea and Kaliningrad Oblast, a Russian exclave, to the north...

 nobleman afflicted with gigantism
Gigantism
Gigantism, also known as giantism , is a condition characterized by excessive growth and height significantly above average...

. While Sardu was a gentle giant in life, and greatly infirmed by his condition, the Master has imbued his form with unnatural power and ferocity. Breaking the territorial truce between himself and the other Ancients, the Master sets into motion a series of events to remake the world in his own dark image. Through the cooperation of Eldritch Palmer, a dying billionaire who craves vampire immortality, the Master has gained unlimited financial and political power to ensure the commencement of his "night eternal". The Master's undead acolytes include Thomas Eichhorst, former Nazi
Nazism
Nazism, the common short form name of National Socialism was the ideology and practice of the Nazi Party and of Nazi Germany...

 commandant of the Treblinka extermination camp, and Gabriel Bolivar, a handsome and charismatic shock rock
Shock rock
Shock rock is an umbrella term for artists who combine rock music with elements of theatrical shock value in live performances.-History:Screamin' Jay Hawkins was arguably the first shock rocker...

er.
Vasiliy Fet

An exterminator
Pest control
Pest control refers to the regulation or management of a species defined as a pest, usually because it is perceived to be detrimental to a person's health, the ecology or the economy.-History:...

 working for the New York City Bureau of Pest Control, Fet's occupation soon leads to his discovering the truth about vampires in a derelict building. Reaching Eph through a professional connection at the CDC, the exterminator lends both his skills as a vermin hunter and his powerful physique to Setrakian and Goodweather's cause. Loyal and unwaveringly brave, he becomes a surrogate son to the old professor.
Augustin Elizalde

A Mexican gang member fresh out of juvenile hall
Youth detention center
A youth detention center, also known as a juvenile detention center , juvenile hall or, more colloquially as juvie, is a secure residential facility for young people, often termed juvenile delinquents, awaiting court hearings and/or placement in long-term care facilities and programs...

, Gus is attacked by a newly turned vampire on the streets of Times Square
Times Square
Times Square is a major commercial intersection in the borough of Manhattan in New York City, at the junction of Broadway and Seventh Avenue and stretching from West 42nd to West 47th Streets...

, and is arrested by the police after throwing the creature under a truck. Learning the truth about vampires from a temporarily incarcerated Setrakian, Gus escapes confinement and finds himself to be a natural vampire slayer on the streets of his tenement neighborhood. Recruited by the other Ancients as a "day hunter" against the Master's exponentially spreading
Exponential growth
Exponential growth occurs when the growth rate of a mathematical function is proportional to the function's current value...

 hordes, Gus assembles a rag-tag band of fighters, including aged luchador
Lucha libre
Lucha libre is a term used in Mexico, and other Spanish-speaking countries, for a form of professional wrestling that has developed within those countries...

 Angel and silver-toothed gangster Alfonso Creem.

Literary Significance and Criticism

The Times Literary Supplement
The Times Literary Supplement
The Times Literary Supplement is a weekly literary review published in London by News International, a subsidiary of News Corporation.-History:...

carried a review by Peter Millar dated 23 May 2009. The review praises the novel's "arresting start" and frequently alludes to Guillermo del Toro's
Guillermo del Toro
Guillermo del Toro is a Mexican director, producer, screenwriter, novelist and designer. He is mostly known for his acclaimed films, Blade II, Pan's Labyrinth and the Hellboy film franchise. He is a frequent collaborator with Ron Perlman, Federico Luppi and Doug Jones...

career as a film director by comparing the novel to a Hollywood movie. The implication may be that del Toro intends to direct the film version of the novel. The review closes by calling The Strain a "rattling piece of escapism" with a "predictable" blockbuster ending.
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