David Peakall
Encyclopedia
David Beaumont Peakall was an internationally recognised toxicologist. His research into the effects of DDE
Dichlorodiphenyldichloroethylene
Dichlorodiphenyldichloroethylene is a chemical compound formed by the loss of hydrogen chloride from DDT, of which it is one of the more common breakdown products. DDE is fat soluble which tends to build up in the fat of animals. Due to its stability in fat, DDE is rarely excreted from the body,...

 and DDT
DDT
DDT is one of the most well-known synthetic insecticides. It is a chemical with a long, unique, and controversial history....

 on eggshells contributed to the ban on DDT in the US. He proved that the chemicals caused thinning of eggshells, leading to a reduction in the population of various bird species. He also pioneered research on the effects of PCBs on birds.

Early years and studies

Peakall was born in Purley
Purley, London
Purley is a place in the London Borough of Croydon, England. It is a suburban development situated 11.7 miles south of Charing Cross.The name derives from "pirlea", which means 'Peartree lea'. Purley has a population of about 72,000....

, Surrey
Surrey
Surrey is a county in the South East of England and is one of the Home Counties. The county borders Greater London, Kent, East Sussex, West Sussex, Hampshire and Berkshire. The historic county town is Guildford. Surrey County Council sits at Kingston upon Thames, although this has been part of...

, England
England
England is a country that is part of the United Kingdom. It shares land borders with Scotland to the north and Wales to the west; the Irish Sea is to the north west, the Celtic Sea to the south west, with the North Sea to the east and the English Channel to the south separating it from continental...

 and lived in Coulsdon
Coulsdon
Coulsdon is a town on the southernmost boundary of the London Borough of Croydon. It is surrounded by the Metropolitan Green Belt of the Farthing Down, Coulsdon Common and Kenley Common...

, Surrey, as a boy. He demonstrated a keen interest in ornithology
Ornithology
Ornithology is a branch of zoology that concerns the study of birds. Several aspects of ornithology differ from related disciplines, due partly to the high visibility and the aesthetic appeal of birds...

 as well as chemistry
Chemistry
Chemistry is the science of matter, especially its chemical reactions, but also its composition, structure and properties. Chemistry is concerned with atoms and their interactions with other atoms, and particularly with the properties of chemical bonds....

, which led him to work as a volunteer at the RSPB reserve at Minsmere
Minsmere
Minsmere is a hamlet on the Suffolk coast a couple of miles south of Dunwich, within the Suffolk Coast and Heaths AONB.Ranulf de Glanvill built an abbey on the marshes here in the 12th century, but this was abandoned in favour of Leiston Abbey in 1363...

. He received a Ph.D.
Ph.D.
A Ph.D. is a Doctor of Philosophy, an academic degree.Ph.D. may also refer to:* Ph.D. , a 1980s British group*Piled Higher and Deeper, a web comic strip*PhD: Phantasy Degree, a Korean comic series* PhD Docbook renderer, an XML renderer...

 in Physical Chemistry
Physical chemistry
Physical chemistry is the study of macroscopic, atomic, subatomic, and particulate phenomena in chemical systems in terms of physical laws and concepts...

 in 1956 from the University of London
University of London
-20th century:Shortly after 6 Burlington Gardens was vacated, the University went through a period of rapid expansion. Bedford College, Royal Holloway and the London School of Economics all joined in 1900, Regent's Park College, which had affiliated in 1841 became an official divinity school of the...

, and a D.Sc. from Oxford University in 1979 for his thesis
Thesis
A dissertation or thesis is a document submitted in support of candidature for an academic degree or professional qualification presenting the author's research and findings...

 on the ecological effects of pollutants. He became a member of the American Ornithologists' Union
American Ornithologists' Union
The American Ornithologists' Union is an ornithological organization in the USA. Unlike the National Audubon Society, its members are primarily professional ornithologists rather than amateur birders...

 in 1961 and an Elective Member in 1972.

Career

In 1960, Walter R. Spofford hired Peakall as a research associate in the Department of Anatomy
Anatomy
Anatomy is a branch of biology and medicine that is the consideration of the structure of living things. It is a general term that includes human anatomy, animal anatomy , and plant anatomy...

 of the Upstate Medical Center in Syracuse
Syracuse, New York
Syracuse is a city in and the county seat of Onondaga County, New York, United States, the largest U.S. city with the name "Syracuse", and the fifth most populous city in the state. At the 2010 census, the city population was 145,170, and its metropolitan area had a population of 742,603...

, New York
New York
New York is a state in the Northeastern region of the United States. It is the nation's third most populous state. New York is bordered by New Jersey and Pennsylvania to the south, and by Connecticut, Massachusetts and Vermont to the east...

, where he used egg albumen protein electrophoresis
Electrophoresis
Electrophoresis, also called cataphoresis, is the motion of dispersed particles relative to a fluid under the influence of a spatially uniform electric field. This electrokinetic phenomenon was observed for the first time in 1807 by Reuss , who noticed that the application of a constant electric...

 to determine phylogenetic relationships in the Falconiformes
Falconiformes
The order Falconiformes is a group of about 290 species of birds that comprises the diurnal birds of prey. Raptor classification is difficult and the order is treated in several ways.- Classification problems :...

. In 1962, he was appointed assistant professor of Pharmacology
Pharmacology
Pharmacology is the branch of medicine and biology concerned with the study of drug action. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function...

. In 1968, he went to Cornell University
Cornell University
Cornell University is an Ivy League university located in Ithaca, New York, United States. It is a private land-grant university, receiving annual funding from the State of New York for certain educational missions...

 as a research affiliate at the Laboratory of Ornithology
Ornithology
Ornithology is a branch of zoology that concerns the study of birds. Several aspects of ornithology differ from related disciplines, due partly to the high visibility and the aesthetic appeal of birds...

 and a senior research associate in the Section of Ecology
Ecology
Ecology is the scientific study of the relations that living organisms have with respect to each other and their natural environment. Variables of interest to ecologists include the composition, distribution, amount , number, and changing states of organisms within and among ecosystems...

 and Systematics
Systematics
Biological systematics is the study of the diversification of terrestrial life, both past and present, and the relationships among living things through time. Relationships are visualized as evolutionary trees...

 in the Biological Sciences Division. He initially worked on making the Laboratory of Ornithology's Nest Record Card Program accessible to researchers. He also worked to emphasize the importance of spatial and temporal data on bird nesting.

This led to Peakall working full time on raptor
Bird of prey
Birds of prey are birds that hunt for food primarily on the wing, using their keen senses, especially vision. They are defined as birds that primarily hunt vertebrates, including other birds. Their talons and beaks tend to be relatively large, powerful and adapted for tearing and/or piercing flesh....

 pesticide
Pesticide
Pesticides are substances or mixture of substances intended for preventing, destroying, repelling or mitigating any pest.A pesticide may be a chemical unicycle, biological agent , antimicrobial, disinfectant or device used against any pest...

 problems, combining his passion for birds with his skills as a chemist. He measured DDE
DDE
DDE is a three-letter abbreviation that may refer to:In mathematics:* Delay differential equation* Directional derivative estimationIn computing:* Direct data entry* Double data entry* Dynamic Data ExchangeOther:...

 levels in peregrine
Peregrine Falcon
The Peregrine Falcon , also known as the Peregrine, and historically as the Duck Hawk in North America, is a widespread bird of prey in the family Falconidae. A large, crow-sized falcon, it has a blue-gray back, barred white underparts, and a black head and "moustache"...

 eggs collected in Alaska
Alaska
Alaska is the largest state in the United States by area. It is situated in the northwest extremity of the North American continent, with Canada to the east, the Arctic Ocean to the north, and the Pacific Ocean to the west and south, with Russia further west across the Bering Strait...

 from 1969 to 1973, and showed a strong inverse relationship between DDE content and eggshell thickness. The chemical industry claimed that shell thinning occurred too rapidly after the introduction of DDT
DDT
DDT is one of the most well-known synthetic insecticides. It is a chemical with a long, unique, and controversial history....

 in 1946 for DDT to be the cause. Peakall filled blown peregrine eggs collected from the critical period with solvent and measured DDE in the extracted lipids. DDE was present in sufficient concentrations to account for significant eggshell thinning in 1946 in Great Britain
Great Britain
Great Britain or Britain is an island situated to the northwest of Continental Europe. It is the ninth largest island in the world, and the largest European island, as well as the largest of the British Isles...

 and as early as 1948 in California
California
California is a state located on the West Coast of the United States. It is by far the most populous U.S. state, and the third-largest by land area...

. Later, he would apply similar methods to California Condor
California Condor
The California Condor is a New World vulture, the largest North American land bird. Currently, this condor inhabits only the Grand Canyon area, Zion National Park, and coastal mountains of central and southern California and northern Baja California...

 eggshell fragments as evidence that this species was extremely sensitive to DDE. His testimony at U.S. congressional hearings contributed to the banning of DDT use in the United States. While at Cornell, Peakall also conducted studies on the ability of pesticides to induce breakdown of steroids, to alter vitamin D
Vitamin D
Vitamin D is a group of fat-soluble secosteroids. In humans, vitamin D is unique both because it functions as a prohormone and because the body can synthesize it when sun exposure is adequate ....

 metabolism
Metabolism
Metabolism is the set of chemical reactions that happen in the cells of living organisms to sustain life. These processes allow organisms to grow and reproduce, maintain their structures, and respond to their environments. Metabolism is usually divided into two categories...

 and calcium
Calcium
Calcium is the chemical element with the symbol Ca and atomic number 20. It has an atomic mass of 40.078 amu. Calcium is a soft gray alkaline earth metal, and is the fifth-most-abundant element by mass in the Earth's crust...

 up-take, and on the role of carbonic anhydrase
Carbonic anhydrase
The carbonic anhydrases form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons , a reversible reaction that occurs rather slowly in the absence of a catalyst...

 and calcium ATPase
Calcium ATPase
Calcium ATPase is a form of P-ATPase that transfers calcium after a muscle has contracted. The calcium ATPase are:*Plasma membrane Ca2+ ATPase *Sarcoplasmic reticulum Ca2+ ATPase - Plasma membrane Ca2+ ATPase :...

 in eggshell thinning. He also pioneered research on the effects of PCBs on birds.

In 1975, Peakall went to Ottawa
Ottawa
Ottawa is the capital of Canada, the second largest city in the Province of Ontario, and the fourth largest city in the country. The city is located on the south bank of the Ottawa River in the eastern portion of Southern Ontario...

 to become a research scientist and Chief of the Toxic Chemicals Division in the Canadian Wildlife Service
Canadian Wildlife Service
The Canadian Wildlife Service or CWS is a branch of the Department of the Environment, also known as Environment Canada, a department of the Government of Canada....

 (CWS) of Environment Canada
Environment Canada
Environment Canada , legally incorporated as the Department of the Environment under the Department of the Environment Act Environment Canada (EC) (French: Environnement Canada), legally incorporated as the Department of the Environment under the Department of the Environment Act Environment...

. During his leadership, the contributions of the Division increased in magnitude and scope. To the existing strengths in analytical chemistry
Analytical chemistry
Analytical chemistry is the study of the separation, identification, and quantification of the chemical components of natural and artificial materials. Qualitative analysis gives an indication of the identity of the chemical species in the sample and quantitative analysis determines the amount of...

, field biology, pesticide registration and tissue banking, he added specialists in cytogenetics
Cytogenetics
Cytogenetics is a branch of genetics that is concerned with the study of the structure and function of the cell, especially the chromosomes. It includes routine analysis of G-Banded chromosomes, other cytogenetic banding techniques, as well as molecular cytogenetics such as fluorescent in situ...

, heavy metals
Heavy metals
A heavy metal is a member of a loosely-defined subset of elements that exhibit metallic properties. It mainly includes the transition metals, some metalloids, lanthanides, and actinides. Many different definitions have been proposed—some based on density, some on atomic number or atomic weight,...

 and biochemical toxicology, and a team to focus on the problems of fish-eating birds of the Great Lakes
Great Lakes
The Great Lakes are a collection of freshwater lakes located in northeastern North America, on the Canada – United States border. Consisting of Lakes Superior, Michigan, Huron, Erie, and Ontario, they form the largest group of freshwater lakes on Earth by total surface, coming in second by volume...

. He established an aviary and techniques to uncover the physiological mechanisms of pollutant effects observed in the field. He became an adjunct professor at the University of Ottawa
University of Ottawa
The University of Ottawa is a bilingual, research-intensive, non-denominational, international university in Ottawa, Ontario. It is one of the oldest universities in Canada. It was originally established as the College of Bytown in 1848 by the Missionary Oblates of Mary Immaculate...

.

Peakall's major contribution to the Great Lakes gull work was an egg swap programme between "clean" and "dirty" colonies, to isolate the effect of parental behavior from that of embryo toxicity. He also participated in analyzing the effects on songbirds of spraying New Brunswick
New Brunswick
New Brunswick is one of Canada's three Maritime provinces and is the only province in the federation that is constitutionally bilingual . The provincial capital is Fredericton and Saint John is the most populous city. Greater Moncton is the largest Census Metropolitan Area...

 forests, fostered the long-term monitoring of contaminant residues in seabird eggs, and for many years was key to the success of the Research Advisory Board of the WWF-CWS Wildlife Toxicology Fund. Peakall guided his scientific team in their collaborative investigations with CWS regional biologists on such problems as reproductive declines in falcons, effects of mercury
Mercury (element)
Mercury is a chemical element with the symbol Hg and atomic number 80. It is also known as quicksilver or hydrargyrum...

 and acid precipitation on loons and other waterfowl, and the effects of dioxin in pulp mill effluent on Great Blue Heron
Great Blue Heron
The Great Blue Heron is a large wading bird in the heron family Ardeidae, common near the shores of open water and in wetlands over most of North and Central America as well as the West Indies and the Galápagos Islands. It is a rare vagrant to Europe, with records from Spain, the Azores and England...

 reproduction. From 1979 to 1985, he conducted his own extensive collaborative research program on the sub-lethal effects of oil on seabirds, working at the Mount Desert Island
Mount Desert Island
Mount Desert Island , in Hancock County, Maine, is the largest island off the coast of Maine. With an area of it is the 6th largest island in the contiguous United States. Though it is often claimed to be the third largest island on the eastern seaboard of the United States, it is actually second...

 Biological Lab in Maine
Maine
Maine is a state in the New England region of the northeastern United States, bordered by the Atlantic Ocean to the east and south, New Hampshire to the west, and the Canadian provinces of Quebec to the northwest and New Brunswick to the northeast. Maine is both the northernmost and easternmost...

 and Memorial University in Newfoundland
Newfoundland and Labrador
Newfoundland and Labrador is the easternmost province of Canada. Situated in the country's Atlantic region, it incorporates the island of Newfoundland and mainland Labrador with a combined area of . As of April 2011, the province's estimated population is 508,400...

. He retired from CWS in 1991, moving to Wimbledon
Wimbledon, London
Wimbledon is a district in the south west area of London, England, located south of Wandsworth, and east of Kingston upon Thames. It is situated within Greater London. It is home to the Wimbledon Tennis Championships and New Wimbledon Theatre, and contains Wimbledon Common, one of the largest areas...

, England, a few miles from his childhood home.

Retirement

In retirement, Peakall remained very active in the fields of toxicology and ornithology. For several years he was a visiting fellow at the University of Reading
University of Reading
The University of Reading is a university in the English town of Reading, Berkshire. The University was established in 1892 as University College, Reading and received its Royal Charter in 1926. It is based on several campuses in, and around, the town of Reading.The University has a long tradition...

 where he lectured in ecotoxicology, coauthored the widely acclaimed textbook Principles of Ecotoxicology, and in 1992 became a founding coeditor of the new and successful journal Ecotoxicology. In 1996, he coauthored Beyond Silent Spring
Silent Spring
Silent Spring is a book written by Rachel Carson and published by Houghton Mifflin on 27 September 1962. The book is widely credited with helping launch the environmental movement....

, and helped to organize a U.S. Department of Energy-funded international workshop on "Nondestructive Biomarkers in Vertebrates." He organized at least two NATO-funded advanced workshops

Personal life

Peakall's interests included the study of spiders, cooking
Cooking
Cooking is the process of preparing food by use of heat. Cooking techniques and ingredients vary widely across the world, reflecting unique environmental, economic, and cultural traditions. Cooks themselves also vary widely in skill and training...

, literature
Literature
Literature is the art of written works, and is not bound to published sources...

, travel
Travel
Travel is the movement of people or objects between relatively distant geographical locations. 'Travel' can also include relatively short stays between successive movements.-Etymology:...

 and art
Art
Art is the product or process of deliberately arranging items in a way that influences and affects one or more of the senses, emotions, and intellect....

, and a love of cricket
Cricket
Cricket is a bat-and-ball game played between two teams of 11 players on an oval-shaped field, at the centre of which is a rectangular 22-yard long pitch. One team bats, trying to score as many runs as possible while the other team bowls and fields, trying to dismiss the batsmen and thus limit the...

. He enjoyed birding and attending cricket matches; he was a life-long Surrey
Surrey County Cricket Club
Surrey County Cricket Club is one of the 18 professional county clubs which make up the English and Welsh domestic cricket structure, representing the historic county of Surrey. Its limited overs team is called the Surrey Lions...

supporter.
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