Timeline of antibiotics - AbsoluteAstronomy.com

This is the timeline of antimicrobial

Antimicrobial

An anti-microbial is a substance that kills or inhibits the growth of microorganisms such as bacteria, fungi, or protozoans. Antimicrobial drugs either kill microbes or prevent the growth of microbes...

(anti-infective) therapy.
The years show when given was released onto the pharmaceutical
market. Please note that this is NOT a timeline of the antibiotic itself!

1910 - Arsphenamine
Arsphenamine
Arsphenamine, also known as Salvarsan and 606, is a drug that was used beginning in the 1910s to treat syphilis and trypanosomiasis...

aka Salvarsan
1912 - Neosalvarsan
Neosalvarsan
Neosalvarsan is a synthetic chemotherapeutic that is an organoarsenic compound. It became available in 1912 and superseded the more toxic and less water-soluble salvarsan as an effective treatment for syphilis...
1935 - Prontosil
Prontosil
Prontosil, the first commercially available antibacterial antibiotic , was developed by a research team at the Bayer Laboratories of the IG Farben conglomerate in Germany...

(an oral precursor to sulfanilimide)
1936 - Sulfanilimide
1938 - Sulfapyridine
Sulfapyridine
Sulfapyridine, original UK spelling Sulphapyridine, is a sulfonamide antibacterial. At one time it was commonly referred to as M&B....

(M&B 693)
1939 - sulfacetamide
Sulfacetamide
Sulfacetamide is a sulfonamide antibiotic.-Uses:Sulfacetamide 10% topical lotion, sold under the brand name Klaron or Ovace, is approved for the treatment of acne and seborrheic dermatitis. When combined with sulfur, it is sold under the brand names Plexion, Clenia, Prascion, and Avar, which...
1940 - sulfamethizole
Sulfamethizole
Sulfamethizole is a sulfonamide antibiotic.-External links:...
1942 - benzylpenicillin
Benzylpenicillin
Benzylpenicillin, commonly known as penicillin G, is the gold standard type of penicillin. 'G' in the name 'Penicillin G' refers to 'Gold Standard'. Penicillin G is typically given by a parenteral route of administration because it is unstable in the hydrochloric acid of the stomach...
1942 - gramicidin S
Gramicidin S
Gramicidin S or Gramicidin Soviet is an antibiotic effective against some Gram positive and Gram negative bacteria as well as some fungi. It is a derivative of gramicidin, produced by the Gram positive bacterium Bacillus brevis...
1942 - sulfadimidine
Sulfadimidine
Sulfadimidine or sulfamethazine, is a sulfonamide antibacterial.There are non-standardized abbreviations for it as "sulfadimidine" and as "sulfamethazine"...
1943 - sulfamerazine
Sulfamerazine
Sulfamerazine is a sulfonamide antibacterial....
1944 - streptomycin
Streptomycin
Streptomycin is an antibiotic drug, the first of a class of drugs called aminoglycosides to be discovered, and was the first antibiotic remedy for tuberculosis. It is derived from the actinobacterium Streptomyces griseus. Streptomycin is a bactericidal antibiotic. Streptomycin cannot be given...
1947 - sulfadiazine
Sulfadiazine
Sulfadiazine is a sulfonamide antibiotic.-Uses:It eliminates bacteria that cause infections by stopping the production of folic acid inside the bacterial cell, and is commonly used to treat urinary tract infections ....
1948 - chlortetracycline
Chlortetracycline
Chlortetracycline is a tetracycline antibiotic, and was the first tetracycline to be identified. It was discovered in 1945 by Dr. Benjamin Duggar working at Lederle Laboratories under the supervision of Dr.Subba Rao...
1949 - chloramphenicol
Chloramphenicol
Chloramphenicol is a bacteriostatic antimicrobial that became available in 1949. It is considered a prototypical broad-spectrum antibiotic, alongside the tetracyclines, and as it is both cheap and easy to manufacture it is frequently found as a drug of choice in the third world.Chloramphenicol is...
1949 - neomycin
Neomycin
Neomycin is an aminoglycoside antibiotic that is found in many topical medications such as creams, ointments, and eyedrops. The discovery of Neomycin dates back to 1949. It was discovered in the lab of Selman Waksman, who was later awarded the Nobel Prize in Physiology and medicine in 1951...
1950 - oxytetracycline
Oxytetracycline
Oxytetracycline was the second of the broad-spectrum tetracycline group of antibiotics to be discovered.Oxytetracycline works by interfering with the ability of bacteria to produce proteins that are essential to them. Without these proteins the bacteria cannot grow, multiply and increase in numbers...
1950 - penicillin G procaine
1952 - erythromycin
Erythromycin
Erythromycin is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin, and is often used for people who have an allergy to penicillins. For respiratory tract infections, it has better coverage of atypical organisms, including mycoplasma and...
1954 - benzathine penicillin
1955 - spiramycin
Spiramycin
Spiramycin is a macrolide antibiotic. It is used to treat toxoplasmosis. Although used in Europe, Canada and Mexico, spiramycin is still considered an experimental drug in the United States, but can sometimes be obtained by special permission from the FDA for toxoplasmosis in the first trimester of...
1955 - tetracycline
1955 - thiamphenicol
Thiamphenicol
Thiamphenicol is an antibiotic. It is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Like chloramphenicol, it is insoluble in water, but highly soluble in lipids...
1955 - vancomycin
Vancomycin
Vancomycin INN is a glycopeptide antibiotic used in the prophylaxis and treatment of infections caused by Gram-positive bacteria. It has traditionally been reserved as a drug of "last resort", used only after treatment with other antibiotics had failed, although the emergence of...
1956 - phenoxymethylpenicillin
Phenoxymethylpenicillin
Phenoxymethylpenicillin, commonly known as penicillin V, is a penicillin antibiotic that is orally active. It is less active than benzylpenicillin against Gram-negative bacteria. Phenoxymethylpenicillin is more acid-stable than benzylpenicillin, which allows it to be given orally...
1958 - colistin
Colistin
Colistin is a polymyxin antibiotic produced by certain strains of Bacillus polymyxa var. colistinus. Colistin is a mixture of cyclic polypeptides colistin A and B. Colistin is effective against most Gram-negative bacilli and is used as a lingerdoodle. It is one of the last-resort antibiotics for...
1958 - demeclocycline
Demeclocycline
Demeclocycline is a tetracycline antibiotic.It is derived from a strain of Streptomyces aureofaciens.-In infections:...
1959 - virginiamycin
Virginiamycin
Virginiamycin is a streptogramin antibiotic similar to pristinamycin and quinupristin/dalfopristin. It is a combination of pristinamycin IIA and virginiamycin S1. Virginiamycin is used in the fuel ethanol industry to prevent microbial contamination...
1960 - methicillin
Methicillin
Meticillin or methicillin is a narrow-spectrum beta-lactam antibiotic of the penicillin class. It should not be confused with the antibiotic metacycline.-History:Methicillin was developed by Beecham in 1959...
1960 - metronidazole
Metronidazole
Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa. Metronidazole is an antibiotic, amebicide, and antiprotozoal....
1961 - ampicillin
Ampicillin
Ampicillin is a beta-lactam antibiotic that has been used extensively to treat bacterial infections since 1961. Until the introduction of ampicillin by the British company Beecham, penicillin therapies had only been effective against Gram-positive organisms such as staphylococci and streptococci...
1961 - spectinomycin
Spectinomycin
Spectinomycin is an aminocyclitol antibiotic, closely related to the aminoglycosides, produced by the bacterium Streptomyces spectabilis....
1961 - sulfamethoxazole
Sulfamethoxazole
Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic.It is most often used as part of a synergistic combination with trimethoprim in a 5:1 ratio in co-trimoxazole , also known under trade names such as Bactrim, Septrin, or Septra; in Eastern Europe it is marketed as Biseptol...
1961 - trimethoprim
Trimethoprim
Trimethoprim is a bacteriostatic antibiotic mainly used in the prophylaxis and treatment of urinary tract infections.It belongs to the class of chemotherapeutic agents known as dihydrofolate reductase inhibitors...
1962 - cloxacillin
Cloxacillin
Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. Cloxacillin was discovered and developed by Beecham. It is sold under a number of trade names, including Cloxapen, Cloxacap, Tegopen and Orbenin....
1962 - fusidic acid
Fusidic acid
Fusidic acid is a bacteriostatic antibiotic that is often used topically in creams and eyedrops, but may also be given systemically as tablets or injections...
1963 - fusafungine
Fusafungine
Fusafungine , also known as fusafungin, is an active agent used in antibiotics for treatment of nasal and throat infection. It also possesses anti-inflammatory properties...
1963 - lymecycline
Lymecycline
Lymecycline is a tetracycline broad-spectrum antibiotic marketed by the pharmeceutical company Galderma. It is approximately 5000 times more soluble than tetracycline base and is unique amongst tetracyclines in that it is absorbed by an active transport process across the intestinal wall, making...
1964 - gentamicin
Gentamicin
Gentamicin is an aminoglycoside antibiotic, used to treat many types of bacterial infections, particularly those caused by Gram-negative organisms. However, gentamicin is not used for Neisseria gonorrhoeae, Neisseria meningitidis or Legionella pneumophila...
1966 - doxacycline
1967 - carbenicillin
Carbenicillin
Carbenicillin is a bacteriolytic antibiotic belonging to the carboxypenicillin subgroup of the penicillins. It was discovered by scientists at Beecham and marketed as Pyopen. It has Gram-negative coverage which includes Pseudomonas aeruginosa but limited Gram-positive coverage...
1967 - rifampicin
Rifampicin
Rifampicin or rifampin is a bactericidal antibiotic drug of the rifamycin group. It is a semisynthetic compound derived from Amycolatopsis rifamycinica ...
1968 - clindamycin
Clindamycin
Clindamycin rINN is a lincosamide antibiotic. It is usually used to treat infections with anaerobic bacteria but can also be used to treat some protozoal diseases, such as malaria...
1970 - cefalexin
Cefalexin
Cefalexin or more commonly cephalexin is a first-generation cephalosporin antibiotic introduced in 1967 by Eli Lilly and Company. It is an orally administered agent with a similar antimicrobial spectrum to the intravenous agents cefalotin and cefazolin...
1971 - cefazolin
Cefazolin
Cefazolin , also known as cefazoline or cephazolin, is a first-generation cephalosporin antibiotic.The drug is usually administrated by either intramuscular injection or intravenous infusion .-Indications:Cefazolin is mainly used to treat bacterial infections of the skin...
1971 - pivampicillin
Pivampicillin
Pivampicillin is a pivaloyloxymethylester of ampicillin. It is a prodrug, which is thought to enhance the oral bioavailability of ampicillin because of its greater lipophilicity compared to that of ampicillin.-Adverse effects:...
1971 - tinidazole
Tinidazole
Tinidazole is an anti-parasitic drug used against protozoan infections. It is widely known throughout Europe and the developing world as treatment for a variety of amoebic and parasitic infections...
1972 - amoxicillin
Amoxicillin
Amoxicillin , formerly amoxycillin , and abbreviated amox, is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms. It is usually the drug of choice within the class because it is better absorbed, following oral...
1972 - cefradine
1972 - minocycline
Minocycline
Minocycline is a broad-spectrum tetracycline antibiotic, and has a broader spectrum than the other members of the group. It is a bacteriostatic antibiotic, classified as a long-acting type...
1972 - pristinamycin
Pristinamycin
Pristinamycin , also spelled pristinamycine, is an antibiotic used primarily in the treatment of staphylococcal infections, and to a lesser extent streptococcal infections. It is a streptogramin group antibiotic, similar to virginiamycin, derived from the bacterium Streptomyces pristinaespiralis...
1973 - fosfomycin
Fosfomycin
Fosfomycin is a broad-spectrum antibiotic produced by certain Streptomyces species.-Uses:...
1974 - talampicillin
Talampicillin
Talampicillin is a beta lactam antibiotic from the penicillin family.prodgug,oral use,ampicilin + 3-oksoftalidstable in acidic...
1975 - tobramycin
1975 - bacampicillin
Bacampicillin
Bacampicillin is a penicillin antibiotic. It is a prodrug of ampicillin with improved oral bioavailability.It is sold under the brand names Spectrobid and Penglobe ....
1975 - ticarcillin
Ticarcillin
Ticarcillin is a carboxypenicillin. It is almost invariably sold and used in combination with clavulanate as Timentin. Because it is a penicillin, it also falls within the larger class of beta-lactam antibiotics. Its main clinical use is as an injectable antibiotic for the treatment of...
1976 - amikacin
Amikacin
Amikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections. Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to its growth.-Administration:Amikacin may be...
1977 - azlocillin
Azlocillin
Azlocillin is an acylampicillin antibiotic with an extended spectrum of activity and greater in vitro potency than the carboxy penicillins.Azlocillin is similar to mezlocillin and piperacillin...
1977 - cefadroxil
Cefadroxil
Cefadroxil is a broad-spectrum antibiotic of the cephalosporin type, effective in Gram-positive and Gram-negative bacterial infections. It is a bactericidal antibiotic.- General use :...
1977 - cefamandole
Cefamandole
Cefamandole is a second-generation broad-spectrum cephalosporin antibiotic. The clinically used form of cefamandole is the formate ester cefamandole nafate, a prodrug which is administered parenterally....
1977 - cefoxitin
Cefoxitin
Cefoxitin is a cephamycin antibiotic developed by Merck & Co., Inc., often grouped with the second−generation cephalosporins. It is sold under the brand name Mefoxin.- Microbiology :...
1977 - cefuroxime
Cefuroxime
Cefuroxime is a second-generation cephalosporin antibiotic that has been widely available in the USA as Ceftin since 1977. GlaxoSmithKline sells the antibiotic in the United Kingdom under the name Zinnat.-Indications:As for the other cephalosporins, although as a...
1977 - mezlocillin
Mezlocillin
Mezlocillin is a broad-spectrum penicillin antibiotic. It is active against both Gram-negative and some Gram-positive bacteria. Unlike most other extended spectrum penicillins, it is excreted by the liver, therefore it is useful for biliary tract infections, such as ascending colangitis.-Mechanism...
1977 - pivmecillinam
Pivmecillinam
Pivmecillinam or amdinocillin pivoxil is an orally-active prodrug of mecillinam, an extended-spectrum penicillin antibiotic. Pivmecillinam is the pivaloyloxymethyl ester of mecillinam...
1979 - cefaclor
Cefaclor
Cefaclor, also known as cefachlor or cefaclorum , is a second-generation cephalosporin antibiotic used to treat certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections.- Indications:Cefaclor belongs to the family of antibiotics known as the...
1980 - cefmetazole
Cefmetazole
Cefmetazole is a cephalosporin antibiotic, usually grouped with the second-generation cephalosporins.-Adverse effects:The chemical structure of cefmetazole, like that of several other cephalosporins, contains an N-methylthiotetrazole side chain...
1980 - cefotaxime
Cefotaxime
Cefotaxime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria...
1980 - cefsulodin
Cefsulodin
Cefsulodin is a third generation cephalosporin antibiotic that has very specific activity against Pseudomonas aeruginosa. It has no significant activity against other Gram-negative bacteria and very limited activity against Gram-positive bacteria and anaerobic bacteria. Cefsulodin was first...
1980 - piperacillin
Piperacillin
Piperacillin is an extended spectrum beta-lactam antibiotic of the ureidopenicillin class.It is normally used together with a beta-lactamase inhibitor such as tazobactam. The combination drug piperacillin/tazobactam is commercially available as e.g. Tazocin, Zosyn, Brodactam, Piptaz and as Trezora...
1981 - amoxicillin
Amoxicillin
Amoxicillin , formerly amoxycillin , and abbreviated amox, is a moderate-spectrum, bacteriolytic, β-lactam antibiotic used to treat bacterial infections caused by susceptible microorganisms. It is usually the drug of choice within the class because it is better absorbed, following oral...

/clavulanic acid
Clavulanic acid
Clavulanic acid is a competitive β-lactamase inhibitor combined with penicillin group antibiotics to overcome certain types of antibiotic resistance. It is used to overcome resistance in bacteria that secrete β-lactamase, which otherwise inactivates most penicillins...

(co-amoxiclav
Co-amoxiclav
Amoxicillin/clavulanic acid or co-amoxiclav is a combination antibiotic consisting of amoxicillin trihydrate, a β-lactam antibiotic, and potassium clavulanate, a β-lactamase inhibitor...

)
1981 - cefperazone
1981 - cefotiam
Cefotiam
Cefotiam is a second-generation cephalosporin antibiotic....
1981 - cefsulodin
Cefsulodin
Cefsulodin is a third generation cephalosporin antibiotic that has very specific activity against Pseudomonas aeruginosa. It has no significant activity against other Gram-negative bacteria and very limited activity against Gram-positive bacteria and anaerobic bacteria. Cefsulodin was first...
1981 - latamoxef
Latamoxef
Latamoxef is an oxacephem antibiotic usually grouped with the cephalosporins. In oxacephems such as latamoxef, the sulfur atom of the cephalosporin core is replaced with an oxygen atom....
1981 - netelmicin
1982 - apalcillin
1982 - ceftriaxone
Ceftriaxone
Ceftriaxone is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram-positive and Gram-negative bacteria. In most cases, it is considered to be equivalent to cefotaxime in terms of safety and efficacy...
1982 - micronomicin
Micronomicin
Micronomicin is an aminoglycoside antibiotic....
1983 - cefmenoxime
Cefmenoxime
Cefmenoxime is a third-generation cephalosporin antibiotic....
1983 - ceftazidime
Ceftazidime
Ceftazidime is a third-generation cephalosporin antibiotic. Like other third-generation cephalosporins, it has broad spectrum activity against Gram-positive and Gram-negative bacteria. Unlike most third-generation agents, it is active against Pseudomonas aeruginosa, however it has weaker activity...
1983 - ceftiroxime
1983 - norfloxacin
Norfloxacin
Norfloxacin is a synthetic chemotherapeutic antibacterial agent occasionally used to treat common as well as complicated urinary tract infections. It is sold under various brand names with the most common being Noroxin. In form of ophthalmic solutions it is known as Chibroxin...
1984 - cefonicid
Cefonicid
Cefonicide is a cephalosporin antibiotic.It has a density of 1.92g/cm3....
1984 - cefotetan
Cefotetan
Cefotetan is an injectable antibiotic of the cephamycin type for prophylaxis and treatment of bacterial infections. It is often grouped together with second-generation cephalosporins and has a similar antibacterial spectrum, but with additional anti-anaerobe coverage.Cefotetan was developed by...
1984 - temocillin
Temocillin
Temocillin is a β-lactamase resistant penicillin introduced by Beecham, marketed by Eumedica Pharmaceuticals as Negaban primarily for the treatment of multiresistant Gram negative bacteria.It is a carboxypenicillin.-Pharmacology:...
1985 - cefpiramide
Cefpiramide
Cefpiramide is a third-generation cephalosporin antibiotic....
1985 - imipenem
Imipenem
Imipenem is an intravenous β-lactam antibiotic developed in 1980. It has an extremely broad spectrum of activity.Imipenem belongs to the subgroup of carbapenems. It is derived from a compound called thienamycin, which is produced by the bacterium Streptomyces cattleya...

/cilastatin
Cilastatin
Cilastatin is a chemical compound which inhibits the human enzyme dehydropeptidase.Dehydropeptidase is found in the kidney and is responsible for degrading the antibiotic imipenem. Cilastatin is therefore combined intravenously with imipenem in order to protect it from dehydropeptidase and prolong...
1985 - ofloxacin
Ofloxacin
Ofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class considered to be a second-generation fluoroquinolone. The original brand, Floxin, has been discontinued by the manufacturer in the United States on 18 June 2009, though generic equivalents continue to be...
1986 - mupirocin
Mupirocin
Mupirocin is an antibiotic originally isolated from Pseudomonas fluorescens NCIMB 10586, developed by Beecham....
1986 - aztreonam
Aztreonam
Aztreonam is a synthetic monocyclic beta-lactam antibiotic , with the nucleus based on a simpler monobactam isolated from Chromobacterium violaceum. It was approved by the U.S. Food and Drug Administration in 1986...
1986 - cefoperazone
Cefoperazone
Cefoperazone is a third generation cephalosporin antibiotic, marketed by Pfizer under the name Cefobid, and also marked by pharco B international under the name of Cefazoneand also marketed by "sigmatec " under the name " cefoperazone"...

/sulbactam
Sulbactam
Sulbactam is a molecule that is given in combination with beta-lactam antibiotics to inhibit beta-lactamase, an enzyme produced by bacteria that destroys the antibiotics...
1986 - ticarcillin
Ticarcillin
Ticarcillin is a carboxypenicillin. It is almost invariably sold and used in combination with clavulanate as Timentin. Because it is a penicillin, it also falls within the larger class of beta-lactam antibiotics. Its main clinical use is as an injectable antibiotic for the treatment of...

/clavulanic acid
1987 - ampicillin/sulbactam
Ampicillin/sulbactam
Ampicillin/sulbactam is a combination of the common penicillin-derived antibiotic ampicillin and sulbactam, an inhibitor of bacterial beta-lactamase. Two different forms of the drug exist. The first, developed in 1987 and marketed in the United States under the tradename Unasyn, is an intravenous...
1987 - cefixime
Cefixime
Cefixime is an oral third generation cephalosporin antibiotic. Cefixime is a cephalosporin antibiotic used to treat infections caused by bacteria such as pneumonia; bronchitis; gonorrhea; and ear, lung, throat, and urinary tract infections...
1987 - roxithromycin
Roxithromycin
Roxithromycin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Roxithromycin is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring...
1987 - sultamicillin
Sultamicillin
Sultamicillin is an oral form of the antibiotic combination ampicillin/sulbactam. It contains esterified ampicillin and sulbactam and is marketed under a number of trade names, including Saltum and Unasyn- References :...
1987 - ciprofloxacin
Ciprofloxacin
Ciprofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class.It is a second-generation fluoroquinolone antibacterial. It kills bacteria by interfering with the enzymes that cause DNA to rewind after being copied, which stops synthesis of DNA and of...
1987 - rifaximin
1988 - azithromycin
Azithromycin
Azithromycin is an azalide, a subclass of macrolide antibiotics. Azithromycin is one of the world's best-selling antibiotics...
1988 - flomoxef
Flomoxef
Flomoxef is an oxacephem antibiotic.It has been identified as second-generation and fourth generation....
1988 - isepamycin
1988 - midecamycin
Midecamycin
Midecamycin is a macrolide antibiotic. Synthesized from Streptomyces mycarofaciens.-Physical Properties:Melting point vary depending on the compound type. It may also vary depending on the source consulted...
1988 - rifapentine
Rifapentine
Rifapentine is an antibiotic drug used in the treatment of tuberculosis.-History:...
1988 - teicoplanin
Teicoplanin
Teicoplanin is an antibiotic used in the prophylaxis and treatment of serious infections caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus and Enterococcus faecalis. It is a glycopeptide antibiotic extracted from Actinoplanes teichomyceticus, with a similar...
1989 - cefpodoxime
Cefpodoxime
Cefpodoxime is an oral third generation cephalosporin antibiotic. It is marketed as the prodrug cefpodoxime proxetil by Pharmacia & Upjohn under the trade name Vantin. It is active against most Gram positive and Gram negative organisms. Notable exceptions include Pseudomonas aeruginosa,...
1989 - enrofloxacin
Enrofloxacin
Enrofloxacin is a fluoroquinolone antibiotic sold by the Bayer Corporation under the trade name Baytril. Enrofloxacin is currently FDA-approved for treatment of individual pets and domestic animals in the United States...
1989 - lomefloxacin
Lomefloxacin
Lomefloxacin hydrochloride , is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and urinary tract infections. It is also used to prevent urinary tract infections prior to surgery...
1990 - arbekacin
Arbekacin
Arbekacin is a semisynthetic aminoglycoside antibiotic. It is primarily used for the treatment of infections caused by multi-resistant bacteria including methicillin-resistant Staphylococcus aureus . Arbekacin was originally synthesized from dibekacin in 1973. It has been registered and marketed...
1990 - cefozidime
1990 - clarithromycin
Clarithromycin
Clarithromycin is a macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia , skin and skin structure infections...
1991 - cefdinir
Cefdinir
Cefdinir is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, proven effective for common bacterial infections of the ear, sinus, throat, and skin. It was approved by the U.S...
1992 - cefetamet
Cefetamet
Cefetamet is a cephalosporin antibiotic....
1992 - cefpirome
Cefpirome
Cefpirome is a fourth-generation cephalosporin. Trade names include Cefrom, Keiten, Broact, Cefir. Cefpirome is considered highly active against Gram-negative bacteria, including Pseudomonas aeruginosa, and Gram-positive bacteria....
1992 - cefprozil
Cefprozil
Cefprozil, sometimes spelled cefproxil and marketed under the trade name Cefzil, is a second-generation cephalosporin type antibiotic. In Europe it is marketed using the trade names Procef and Cronocef. It can be used to treat bronchitis, ear infections, skin infections, and other bacterial...
1992 - ceftibufen
1992 - fleroxacin
Fleroxacin
Fleroxacin is a quinolone. It is sold under the brand names Quinodis and Megalocin....
1992 - loracarbef
Loracarbef
Loracarbef is an antibiotic. Its use was discontinued in 2006. It is a carbacephem, but it is sometimes grouped together with the second-generation cephalosporin antibiotics. It was marketed under the trade name Lorabid....
1992 - piperacillin
Piperacillin
Piperacillin is an extended spectrum beta-lactam antibiotic of the ureidopenicillin class.It is normally used together with a beta-lactamase inhibitor such as tazobactam. The combination drug piperacillin/tazobactam is commercially available as e.g. Tazocin, Zosyn, Brodactam, Piptaz and as Trezora...

/tazobactam
Tazobactam
Tazobactam is a compound that inhibits the action of bacterial beta-lactamases. It is added to the extended spectrum beta-lactam antibiotic piperacillin to produce Tazocin or Zosyn or Piprataz...
1992 - rufloxacin
Rufloxacin
Rufloxacin is a quinolone. It is sold under the brand names, Ruflox, Monos, Qari, Tebraxin, Uroflox, Uroclar....
1993 - brodimoprim
Brodimoprim
Brodimoprim is a structural derivative of trimethoprim. In brodimoprim, the 4-methoxy group of trimethoprim is replaced with a bromine atom.As trimethoprim, brodimoprim is a selective inhibitor of bacterial dihydrofolate reductase....
1993 - dirithromycin
Dirithromycin
Dirithromycin is a macrolide glycopeptide antibiotic.Dirithromycin is a more lipid-soluble prodrug derivative of 9S-erythromycyclamine prepared by condensation of the latter with 2-acetaldehyde...
1993 - levofloxacin
Levofloxacin
Levofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class and is used to treat severe or life-threatening bacterial infections or bacterial infections that have failed to respond to other antibiotic classes. It is sold under various brand names, such as Levaquin and...
1993 - nadifloxacin
Nadifloxacin
Nadifloxacin is a topical fluoroquinolone antibiotic for the treatment of acne vulgaris...
1993 - panipenem
Panipenem
Panipenem is a carbapenem antibiotic used in combination with betamipron....

/betamipron
Betamipron
Betamipron or N-benzoyl-β-alanine is a chemical compound which is used together with panipenem to inhibit panipenem uptake into the renal tubule and prevent nephrotoxicity....
1993 - sparfloxacin
Sparfloxacin
Sparfloxacin , trade names Zagam and Zagam Respipac, is a fluoroquinolone antibiotic used in the treatment of bacterial infections. It has a controversial safety profile...
1994 - cefepime
Cefepime
Cefepime is a fourth-generation cephalosporin antibiotic developed in 1994. Cefepime has an extended spectrum of activity against Gram-positive and Gram-negative bacteria, with greater activity against both Gram-negative and Gram-positive organisms than third-generation agents...
1999 - quinupristin/dalfopristin
Dalfopristin
Dalfopristin is a streptogramin antibiotic derived from pristinamycin IIA. The combination quinupristin/dalfopristin, in a weight-to-weight ratio of 30% quinupristin to 70% dalfopristin, is used to treat infections by staphylococci and by vancomycin-resistant Enterococcus faecium....
2000 - linezolid
Linezolid
Linezolid is a synthetic antibiotic used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics...
2001 - telithromycin
Telithromycin
Telithromycin is the first ketolide antibiotic to enter clinical use. It is used to treat mild to moderate respiratory infections. Telithromycin is sold under the brand name of Ketek....
2003 - daptomycin
Daptomycin
Daptomycin is a novel lipopeptide antibiotic used in the treatment of certain infections caused by Gram-positive organisms. It is a naturally occurring compound found in the soil saprotroph Streptomyces roseosporus. Its distinct mechanism of action means that it may be useful in treating infections...
2005 - tigecycline
Tigecycline
Tigecycline is a glycylcycline antibiotic developed by Francis Tally and marketed by Wyeth under the brand name Tygacil. It was given a U.S. Food and Drug Administration fast-track approval and was approved on June 17, 2005...
2005 - doripenem
Doripenem
Doripenem is an ultra-broad spectrum injectable antibiotic. It is a beta-lactam and belongs to the subgroup of carbapenems. It was launched by Shionogi Co. of Japan under the brand name Finibax in 2005 and is being marketed outside Japan by Johnson & Johnson...
2009 - telavancin
Telavancin
Telavancin is a bactericidal lipoglycopeptide for use in MRSA or other Gram-positive infections. Telavancin is a synthetic derivative of vancomycin....

See also