History of tobacco
Encyclopedia
Tobacco has a long history from its usages in the early Americas
Americas
The Americas, or America , are lands in the Western hemisphere, also known as the New World. In English, the plural form the Americas is often used to refer to the landmasses of North America and South America with their associated islands and regions, while the singular form America is primarily...

. It became increasingly popular with the arrival of the Europeans by whom it was heavily traded. Following the industrial revolution, cigarettes became popularized, which fostered yet another unparalleled increase in growth. This remained so until the scientific revelations in the mid-1990s.

Early history

Las Casas vividly described how the first scouts sent by Columbus into the interior of Cuba
Cuba
The Republic of Cuba is an island nation in the Caribbean. The nation of Cuba consists of the main island of Cuba, the Isla de la Juventud, and several archipelagos. Havana is the largest city in Cuba and the country's capital. Santiago de Cuba is the second largest city...

 found

"...men with half-burned wood in their hands and certain herbs to take their smokes, which are some dry herbs put in a certain leaf, also dry, like those the boys make on the day of the Passover of the Holy Ghost; and having lighted one part of it, by the other they
suck, absorb, or receive that smoke inside with the breath, by which they become benumbed and almost drunk, and so it is said they do not feel fatigue. These, muskets as we will call them, they call tabacos. I knew Spaniards on this island of Española who were accustomed to take it, and being reprimanded for it, by telling them it was a vice, they replied they were unable to cease using it. I do not know what relish or benefit they found in it."


Tobacco had already long been used in the Americas by the time European settlers arrived and introduced the practice to Europe, where it became popular. At high doses, tobacco can become hallucinogenic
Psychedelics, dissociatives and deliriants
This general group of pharmacological agents can be divided into three broad categories: psychedelics, dissociatives, and deliriants. These classes of psychoactive drugs have in common that they can cause subjective changes in perception, thought, emotion and consciousness...

; accordingly, Native Americans did not always use the drug recreationally. Instead, it was often consumed as an entheogen
Entheogen
An entheogen , in the strict sense, is a psychoactive substance used in a religious, shamanic, or spiritual context. Historically, entheogens were mostly derived from plant sources and have been used in a variety of traditional religious contexts...

; among some tribes, this was done only by experienced shamans
Shamanism
Shamanism is an anthropological term referencing a range of beliefs and practices regarding communication with the spiritual world. To quote Eliade: "A first definition of this complex phenomenon, and perhaps the least hazardous, will be: shamanism = technique of ecstasy." Shamanism encompasses the...

 or medicine men
Medicine man
"Medicine man" or "Medicine woman" are English terms used to describe traditional healers and spiritual leaders among Native American and other indigenous or aboriginal peoples...

. Eastern North American tribes would carry large amounts of tobacco in pouches as a readily accepted trade item and would often smoke it in pipes, either in defined ceremonies that were considered sacred, or to seal a bargain, and they would smoke it at such occasions in all stages of life, even in childhood. It was believed that tobacco was a gift from the Creator and that the exhaled tobacco smoke was capable of carrying one's thoughts and prayers to heaven
Heaven
Heaven, the Heavens or Seven Heavens, is a common religious cosmological or metaphysical term for the physical or transcendent place from which heavenly beings originate, are enthroned or inhabit...

.

Apart from smoking, tobacco had a number of uses as medicine. As a pain killer it was used for earache and toothache and occasionally as a poultice. Smoking was said by the desert Indians to be a cure for colds, especially if the tobacco was mixed with the leaves of the small Desert Sage, Salvia Dorrii, or the root of Indian Balsam or Cough Root, Leptotaenia multifida, the addition of which was thought to be particularly good for asthma and tuberculosis.
Uncured tobacco was often eaten, used in enemas, or drunk as extracted juice
Juice
Juice is the liquid that is naturally contained in fruit or vegetable tissue.Juice is prepared by mechanically squeezing or macerating fruit or vegetable flesh without the application of heat or solvents. For example, orange juice is the liquid extract of the fruit of the orange tree...

. Early missionaries often reported on the ecstatic state caused by tobacco. As its use spread into Western cultures, however, it was no longer used primarily for entheogenic or religious purposes, although religious use of tobacco is still common among many indigenous peoples, particularly in the Americas. Among the Cree
Cree
The Cree are one of the largest groups of First Nations / Native Americans in North America, with 200,000 members living in Canada. In Canada, the major proportion of Cree live north and west of Lake Superior, in Ontario, Manitoba, Saskatchewan, Alberta and the Northwest Territories, although...

 and Ojibway of Canada and the north-central United States, it is offered to the Creator, with prayer
Prayer
Prayer is a form of religious practice that seeks to activate a volitional rapport to a deity through deliberate practice. Prayer may be either individual or communal and take place in public or in private. It may involve the use of words or song. When language is used, prayer may take the form of...

s, and is used in sweat lodge
Sweat lodge
The sweat lodge is a ceremonial sauna and is an important event in some North American First Nations or Native American cultures...

s, pipe ceremonies, smudging
Smudge stick
A smudge stick is a bundle of dried herbs, most commonly white sage . Often other herbs or plants are added, and the leaves are usually bound with string in a small bundle and dried. Additional herbs and spices that are often used in contemporary practices include cilantro, cedar, lavender, and...

, and is presented as a gift. A gift of tobacco is tradition when asking an Ojibway elder a question of a spiritual nature. Because of its sacred nature, tobacco abuse
Drug abuse
Substance abuse, also known as drug abuse, refers to a maladaptive pattern of use of a substance that is not considered dependent. The term "drug abuse" does not exclude dependency, but is otherwise used in a similar manner in nonmedical contexts...

 (thoughtlessly and addictively chain smoking) is seriously frowned upon by the Algonquian tribes of Canada, as it is believed that if one so abuses the plant, it will abuse that person in return, causing sickness. The proper and traditional native way of offering the smoke is said to involve directing it toward the four cardinal points (north, south, east, and west), rather than holding it deeply within the lungs for prolonged periods.

Rodrigo de Jerez
Rodrigo de Jerez
Rodrigo de Jerez was one of the Spanish crewmen who sailed to the Americas on the Santa Maria as part of Christopher Columbus's first voyage across the Atlantic Ocean in 1492. He is credited with being the first European smoker....

 was one of the Spanish
Spain
Spain , officially the Kingdom of Spain languages]] under the European Charter for Regional or Minority Languages. In each of these, Spain's official name is as follows:;;;;;;), is a country and member state of the European Union located in southwestern Europe on the Iberian Peninsula...

 crewmen who sailed to the Americas on the Santa Maria
Santa María (ship)
La Santa María de la Inmaculada Concepción , was the largest of the three ships used by Christopher Columbus in his first voyage. Her master and owner was Juan de la Cosa.-History:...

 as part of Christopher Columbus
Christopher Columbus
Christopher Columbus was an explorer, colonizer, and navigator, born in the Republic of Genoa, in northwestern Italy. Under the auspices of the Catholic Monarchs of Spain, he completed four voyages across the Atlantic Ocean that led to general European awareness of the American continents in the...

's first voyage across the Atlantic Ocean
Atlantic Ocean
The Atlantic Ocean is the second-largest of the world's oceanic divisions. With a total area of about , it covers approximately 20% of the Earth's surface and about 26% of its water surface area...

 in 1492. He is credited with being the first European smoker.

Following the arrival of Europeans, tobacco became one of the primary products fueling colonization, and also became a driving factor in the incorporation of African slave
African slave trade
Systems of servitude and slavery were common in many parts of Africa, as they were in much of the ancient world. In some African societies, the enslaved people were also indentured servants and fully integrated; in others, they were treated much worse...

 labor.

In the Ottoman Empire

Tobacco as a commercial product first arrived in the Ottoman Empire
Ottoman Empire
The Ottoman EmpireIt was usually referred to as the "Ottoman Empire", the "Turkish Empire", the "Ottoman Caliphate" or more commonly "Turkey" by its contemporaries...

 in the late 16th century.

When tobacco first arrived in the Ottoman Empire, it attracted the attention of doctors and became a commonly prescribed medicine
Medicine
Medicine is the science and art of healing. It encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness....

 for many ailments. Although tobacco was initially prescribed as medicine, further study led to claims that smoking caused dizziness
Dizziness
Dizziness refers to an impairment in spatial perception and stability. The term is somewhat imprecise. It can be used to mean vertigo, presyncope, disequilibrium, or a non-specific feeling such as giddiness or foolishness....

, fatigue, dulling of the senses, and a foul taste/odour in the mouth.

In 1682, Damascene jurist Abd al-Ghani al-Nabulsi declared: “Tobacco has now become extremely famous in all the countries of Islam ... People of all kinds have used it and devoted themselves to it ... I have even seen young children of about five years applying themselves to it.”

In 1750, a Damascene townsmen observed “a number of women greater than the men, sitting along the bank of the Barada River. They were eating and drinking, and drinking coffee and smoking tobacco just as the men were doing.”

In Western Europe

The Spanish introduced tobacco to Europeans in about 1518, and by 1523, Diego Columbus mentioned a tobacco merchant of Lisbon in his will, showing how quickly the traffic had sprung up. Nicot, French ambassador in Lisbon, sent samples to Paris in 1559. The French, Spanish, and Portuguese initially referred to the plant as the "sacred herb" because of its valuable medicinal properties.

In 1571, a Spanish doctor named Nicolas Monardes
Nicolás Monardes
Nicolás Bautista Monardes was a Spanish physician and botanist.The genus Monarda was named for him.Monardes published several books of varying importance. In Diálogo llamado pharmacodilosis , he examines humanism and suggests studying several classical authors, principally Pedanius Dioscorides...

 wrote a book about the history of medicinal plants of the new world. In this he claimed that tobacco could cure 36 health problems.
Sir Walter Raleigh is credited with taking the first "Virginia" tobacco to Europe, referring to it as tobah as early as 1578. In 1595 Anthony Chute
Anthony Chute
Anthony Chute was an Elizabethan poet and pamphleteer. Very little is known about him.Chute appears to have been a protégé of Gabriel Harvey. Harvey refers to him in his work Pierces Supererogation, saying that Chute was an orator and a herald...

 published Tabaco, which repeated earlier arguments about the benefits of the plant and emphasised the health-giving properties of pipe-smoking.

The importation of tobacco into Europe was not without resistance and controversy in the 17th century. Stuart
House of Stuart
The House of Stuart is a European royal house. Founded by Robert II of Scotland, the Stewarts first became monarchs of the Kingdom of Scotland during the late 14th century, and subsequently held the position of the Kings of Great Britain and Ireland...

 King James I
James I of England
James VI and I was King of Scots as James VI from 24 July 1567 and King of England and Ireland as James I from the union of the English and Scottish crowns on 24 March 1603...

 wrote a famous polemic
Polemic
A polemic is a variety of arguments or controversies made against one opinion, doctrine, or person. Other variations of argument are debate and discussion...

 titled A Counterblaste to Tobacco
A Counterblaste to Tobacco
A Counterblaste to Tobacco is a treatise written by King James VI of Scotland and I of England in 1604, in which he expresses his distaste for tobacco, particularly tobacco smoking. As such, it is one of the earliest anti-tobacco publications....

in 1604, in which the king denounced tobacco use as "[a] custome lothsome to the eye, hatefull to the Nose, harmefull to the braine, dangerous to the Lungs, and in the blacke stinking fume thereof, neerest resembling the horrible Stigian
Styx
In Greek mythology the Styx is the river that forms the boundary between the underworld and the world of the living, as well as a goddess and a nymph that represents the river.Styx may also refer to:-Popular culture:...

 smoke of the pit that is bottomelesse
Hell
In many religious traditions, a hell is a place of suffering and punishment in the afterlife. Religions with a linear divine history often depict hells as endless. Religions with a cyclic history often depict a hell as an intermediary period between incarnations...

." In that same year, an English statute
Statute
A statute is a formal written enactment of a legislative authority that governs a state, city, or county. Typically, statutes command or prohibit something, or declare policy. The word is often used to distinguish law made by legislative bodies from case law, decided by courts, and regulations...

 was enacted that placed a heavy protective tariff
Tariff
A tariff may be either tax on imports or exports , or a list or schedule of prices for such things as rail service, bus routes, and electrical usage ....

 on every pound
Pound (mass)
The pound or pound-mass is a unit of mass used in the Imperial, United States customary and other systems of measurement...

 of tobacco brought into England.

In the United States


In 1609, John Rolfe
John Rolfe
John Rolfe was one of the early English settlers of North America. He is credited with the first successful cultivation of tobacco as an export crop in the Colony of Virginia and is known as the husband of Pocahontas, daughter of the chief of the Powhatan Confederacy.In 1961, the Jamestown...

 arrived at Jamestown, Virginia
Jamestown, Virginia
Jamestown was a settlement in the Colony of Virginia. Established by the Virginia Company of London as "James Fort" on May 14, 1607 , it was the first permanent English settlement in what is now the United States, following several earlier failed attempts, including the Lost Colony of Roanoke...

, and is credited as the first settler to have successfully raised tobacco (commonly referred to at that time as "brown gold") for commercial use. The tobacco raised in Virginia at that time, Nicotiana rustica
Nicotiana rustica
Nicotiana rustica, known in South America as Mapacho and in Vietnam as Thuoc Lao , is a plant in the Solanaceae family. It is a very potent variety of tobacco. The high concentration of nicotine in its leaves makes it useful for creating organic pesticides.Rustica is also used for entheogenic...

,
did not suit European tastes, but Rolfe raised a more popular variety, Nicotiana tabacum
Nicotiana tabacum
Nicotiana tabacum, or cultivated tobacco, is a perennial herbaceous plant. It is found only in cultivation, where it is the most commonly grown of all plants in the Nicotiana genus, and its leaves are commercially grown in many countries to be processed into tobacco. It grows to heights between 1...

, from seeds brought with him from Bermuda
Bermuda
Bermuda is a British overseas territory in the North Atlantic Ocean. Located off the east coast of the United States, its nearest landmass is Cape Hatteras, North Carolina, about to the west-northwest. It is about south of Halifax, Nova Scotia, Canada, and northeast of Miami, Florida...

. Tobacco was used as currency
Currency
In economics, currency refers to a generally accepted medium of exchange. These are usually the coins and banknotes of a particular government, which comprise the physical aspects of a nation's money supply...

 by the Virginia settlers for years, and Rolfe was able to make his fortune in farming it for export at Varina Farms Plantation
Varina, Virginia
Varina is a former unincorporated town and current magisterial district in the easternmost portion of Henrico County, Virginia, United States....

. When he left for England
England
England is a country that is part of the United Kingdom. It shares land borders with Scotland to the north and Wales to the west; the Irish Sea is to the north west, the Celtic Sea to the south west, with the North Sea to the east and the English Channel to the south separating it from continental...

 with his wife, Pocahontas
Pocahontas
Pocahontas was a Virginia Indian notable for her association with the colonial settlement at Jamestown, Virginia. She was the daughter of Chief Powhatan, the head of a network of tributary tribal nations in Tidewater Virginia...

 a daughter of Chief Powhatan
Powhatan
The Powhatan is the name of a Virginia Indian confederation of tribes. It is estimated that there were about 14,000–21,000 of these native Powhatan people in eastern Virginia when the English settled Jamestown in 1607...

, he had become wealthy. Returning to Jamestown, following Pocahontas' death in England, Rolfe continued in his efforts to improve the quality of commercial tobacco, and, by 1620, 40000 pounds (18,143.7 kg) of tobacco were shipped to England. By the time John Rolfe died in 1622, Jamestown was thriving as a producer of tobacco, and its population had topped 4,000. Tobacco led to the importation of the colony's first black
African American
African Americans are citizens or residents of the United States who have at least partial ancestry from any of the native populations of Sub-Saharan Africa and are the direct descendants of enslaved Africans within the boundaries of the present United States...

 slaves in 1619. In the year 1616, 2500 pounds (1,134 kg) of tobacco were produced in Jamestown, Virginia
Jamestown, Virginia
Jamestown was a settlement in the Colony of Virginia. Established by the Virginia Company of London as "James Fort" on May 14, 1607 , it was the first permanent English settlement in what is now the United States, following several earlier failed attempts, including the Lost Colony of Roanoke...

, quickly rising up to 119000 pounds (53,977.5 kg) in 1620.

Throughout the 17th and 18th centuries, tobacco continued to be the cash crop
Cash crop
In agriculture, a cash crop is a crop which is grown for profit.The term is used to differentiate from subsistence crops, which are those fed to the producer's own livestock or grown as food for the producer's family...

 of the Virginia Colony, as well as The Carolinas
The Carolinas
The Carolinas is a term used in the United States to refer collectively to the states of North and South Carolina. Together, the two states + have a population of 13,942,126. "Carolina" would be the fifth most populous state behind California, Texas, New York, and Florida...

. Large tobacco warehouses filled the areas near the wharves of new, thriving towns such as Dumfries on the Potomac
Potomac River
The Potomac River flows into the Chesapeake Bay, located along the mid-Atlantic coast of the United States. The river is approximately long, with a drainage area of about 14,700 square miles...

, Richmond
Richmond, Virginia
Richmond is the capital of the Commonwealth of Virginia, in the United States. It is an independent city and not part of any county. Richmond is the center of the Richmond Metropolitan Statistical Area and the Greater Richmond area...

 and Manchester
Manchester, Virginia
Manchester, Virginia is a former independent city in Virginia in the United States. Prior to receiving independent status, it served as the county seat of Chesterfield County, between 1870 and 1876...

 at the fall line
Fall line
A fall line is a geomorphologic unconformity between an upland region of relatively hard crystalline basement rock and a coastal plain of softer sedimentary rock. A fall line is typically prominent when crossed by a river, for there will often be rapids or waterfalls...

 (head of navigation) on the James
James River (Virginia)
The James River is a river in the U.S. state of Virginia. It is long, extending to if one includes the Jackson River, the longer of its two source tributaries. The James River drains a catchment comprising . The watershed includes about 4% open water and an area with a population of 2.5 million...

, and Petersburg
Petersburg, Virginia
Petersburg is an independent city in Virginia, United States located on the Appomattox River and south of the state capital city of Richmond. The city's population was 32,420 as of 2010, predominantly of African-American ethnicity...

 on the Appomattox
Appomattox River
The Appomattox River is a tributary of the James River, approximately long, in central and eastern Virginia in the United States, named for the Appomattocs Indian tribe who lived along its lower banks in the 17th century...

.

Until 1883, tobacco excise tax accounted for one third of internal revenue collected by the United States government.

A historian of the American South in the late 1860s reported on typical usage in the region where it was grown:

In Japan

The Japan
Japan
Japan is an island nation in East Asia. Located in the Pacific Ocean, it lies to the east of the Sea of Japan, China, North Korea, South Korea and Russia, stretching from the Sea of Okhotsk in the north to the East China Sea and Taiwan in the south...

ese were introduced to tobacco by Portuguese
Portugal
Portugal , officially the Portuguese Republic is a country situated in southwestern Europe on the Iberian Peninsula. Portugal is the westernmost country of Europe, and is bordered by the Atlantic Ocean to the West and South and by Spain to the North and East. The Atlantic archipelagos of the...

 sailors from 1542.

In Australia

Tobacco smoking first reached Australian shores when it was introduced to northern-dwelling Indigenous communities by visiting Indonesian fishermen
Macassan contact with Australia
Macassan or more correctly Makassar trepangers from the southwest corner of Sulawesi visited the coast of northern Australia for hundreds of years to process trepang : a marine invertebrate prized for its culinary and medicinal values in Chinese markets.These visits have left their mark on the...

 in the early 18th century. British patterns of tobacco use were transported to Australia along with the new settlers in 1788; and in the years following colonisation, British smoking behaviour was rapidly adopted by Indigenous people as well. By the early 19th century tobacco was an essential commodity routinely issued to servants, prisoners and ticket-of-leave men (conditionally released convicts) as an inducement to work, or conversely, withheld as a means of punishment.

Industrialization

Following the American civil war, the tobacco industry struggled as it attempted to adapt. Not only did the labor force change from slavery to sharecropping, but a change in demand also occurred. As in Europe, there was a desire for not only snuff, pipes and cigars, but cigarettes appeared as well.

With a change in demand and a change in labor force, James Bonsack, an avid craftsman, in 1881 created a machine that revolutionized cigarette production. The machine chopped the tobacco, then dropped a certain amount of the tobacco into a long tube of paper, which the machine would then roll and push out the end where it would be sliced by the machine into individual cigarettes. This machine operated at thirteen times the speed of a human cigarette roller.

This caused an enormous growth in the tobacco industry which remained so until the scientific revelations discovered the health consequences of smoking in the mid-20th century.

Contemporary

In the 1950s tobacco companies engaged in a cigarette advertising
Tobacco advertising
Tobacco advertising is the advertising of tobacco products or use by the tobacco industry through a variety of media including sponsorship, particularly of sporting events. It is now one of the most highly regulated forms of marketing...

 war surrounding the tar
Tar (tobacco residue)
Tar is the common name for the resinous partially combusted and healed particulate matter produced by the burning of tobacco and other plant material in the act of smoking. Tar is purportedly the most destructive component in habitual tobacco smoking, accumulating in the smoker's lungs over time...

 content in cigarettes that came to be known as the tar derby
Tar derby
The tar derby is a term used to describe the period in the 1950s and early 1960s marked by a rapid influx in both cigarette advertising focused on tar content measurements to differentiate cigarettes and brand introduction or repositioning focusing on filter technology...

. The companies repositioned their brands to emphasize low tar content, filter
Cigarette filter
A cigarette filter has the purpose of reducing the amount of smoke, tar, and fine particles inhaled during the combustion of a cigarette. Filters also reduce the harshness of the smoke and keep tobacco flakes out of the smoker's mouth.-History:...

 technology and nicotine levels. The period ended in 1959 after the Federal Trade Commission
Federal Trade Commission
The Federal Trade Commission is an independent agency of the United States government, established in 1914 by the Federal Trade Commission Act...

 (FTC) Chairman and several cigarette company presidents agreed to discontinue usage of tar or nicotine
Nicotine
Nicotine is an alkaloid found in the nightshade family of plants that constitutes approximately 0.6–3.0% of the dry weight of tobacco, with biosynthesis taking place in the roots and accumulation occurring in the leaves...

 levels in advertisements.

In order to reduce the potential burden of disease, the World Health Organization(WHO) successfully rallied 168 countries to sign the Framework Convention on Tobacco Control in 2003. The Convention is designed to push for effective legislation and its enforcement in all countries to reduce the harmful effects of tobacco.

In science

The tobacco smoke enema
Tobacco smoke enema
The tobacco smoke enema, an insufflation of tobacco smoke into the rectum by enema, was a medical treatment employed by European physicians for a range of ailments....

 was the principal medical method to resuscitate victims of drowning
Drowning
Drowning is death from asphyxia due to suffocation caused by water entering the lungs and preventing the absorption of oxygen leading to cerebral hypoxia....

 in the 18th century.

As a lucrative crop, tobacco has been the subject of a great deal of biological and genetic research. The economic impact of Tobacco Mosaic disease was the impetus that led to the isolation of Tobacco mosaic virus
Tobacco mosaic virus
Tobacco mosaic virus is a positive-sense single stranded RNA virus that infects plants, especially tobacco and other members of the family Solanaceae. The infection causes characteristic patterns on the leaves . TMV was the first virus to be discovered...

, the first virus to be identified; the fortunate coincidence that it is one of the simplest viruses and can self-assemble from purified nucleic acid
Nucleic acid
Nucleic acids are biological molecules essential for life, and include DNA and RNA . Together with proteins, nucleic acids make up the most important macromolecules; each is found in abundance in all living things, where they function in encoding, transmitting and expressing genetic information...

 and protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

 led, in turn, to the rapid advancement of the field of virology
Virology
Virology is the study of viruses and virus-like agents: their structure, classification and evolution, their ways to infect and exploit cells for virus reproduction, the diseases they cause, the techniques to isolate and culture them, and their use in research and therapy...

. The 1946 Nobel Prize in Chemistry
Nobel Prize in Chemistry
The Nobel Prize in Chemistry is awarded annually by the Royal Swedish Academy of Sciences to scientists in the various fields of chemistry. It is one of the five Nobel Prizes established by the will of Alfred Nobel in 1895, awarded for outstanding contributions in chemistry, physics, literature,...

 was shared by Wendell Meredith Stanley
Wendell Meredith Stanley
Wendell Meredith Stanley was an American biochemist, virologist and Nobel laureate.-Biography:Stanley was born in Ridgeville, Indiana, and earned a BS in Chemistry at Earlham College in Richmond, Indiana. He then studied at the University of Illinois, gaining an MS in science in 1927 followed by...

for his 1935 work crystallizing the virus and showing that it remains active.

External links

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