Golden S sign
Encyclopedia
In medicine
Medicine
Medicine is the science and art of healing. It encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness....

, the Golden S sign is a sign
Radiologic sign
A radiologic sign is an "objective" indication of some medical fact or quality that is detected by a physician during examination of a radiograph .-Examples:*Football sign*Hampton's hump*Omental cake*Pneumatosis intestinalis...

 seen on imaging
Medical imaging
Medical imaging is the technique and process used to create images of the human body for clinical purposes or medical science...

 of the chest that suggests a central lung
Lung
The lung is the essential respiration organ in many air-breathing animals, including most tetrapods, a few fish and a few snails. In mammals and the more complex life forms, the two lungs are located near the backbone on either side of the heart...

 mass or lung collapse
Atelectasis
Atelectasis is defined as the collapse or closure of alveoli resulting in reduced or absent gas exchange. It may affect part or all of one lung. It is a condition where the alveoli are deflated, as distinct from pulmonary consolidation.It is a very common finding in chest x-rays and other...

. It was first described by Golden in 1925 in association with bronchial carcinoma
Lung cancer
Lung cancer is a disease characterized by uncontrolled cell growth in tissues of the lung. If left untreated, this growth can spread beyond the lung in a process called metastasis into nearby tissue and, eventually, into other parts of the body. Most cancers that start in lung, known as primary...

, but it is also seen in metastatic cancer, enlarged lymph nodes
Lymphadenopathy
Lymphadenopathy is a term meaning "disease of the lymph nodes." It is, however, almost synonymously used with "swollen/enlarged lymph nodes". It could be due to infection, auto-immune disease, or malignancy....

, and collapse
Atelectasis
Atelectasis is defined as the collapse or closure of alveoli resulting in reduced or absent gas exchange. It may affect part or all of one lung. It is a condition where the alveoli are deflated, as distinct from pulmonary consolidation.It is a very common finding in chest x-rays and other...

 of the right upper lobe of the lung.

Appearance

The Golden S sign can be seen on plain radiographs as well as on computed tomography
Computed tomography
X-ray computed tomography or Computer tomography , is a medical imaging method employing tomography created by computer processing...

 (CT) scans of the chest. The sign is seen in the right lung as a distorted minor fissure
Horizontal fissure of right lung
The horizontal fissure of right lung is a fissure separating the superior lobe from the middle lobe.The left lung has no middle lobe, so there is no horizontal fissure on that lung....

, whose lateral aspect is concave inferiorly and whose medial aspect is convex inferiorly. This produces a "reverse S" appearance, responsible for the sign being occasionally called the reverse S sign of Golden.
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