Konstantin Efetov
Encyclopedia
Konstantin Alexandrovich Efetov (born July 18, 1958; ) is a biologist and biochemist, the Honored Scientist of Ukraine, Professor, Dr. Biol. Sci., Head of the Department of Biological Chemistry and Laboratory of Biotechnology of the Crimea State Medical University
.
s for investigation of human protein
s. Since 1995, Efetov is Professor and since 1999, he is the Head of the Department of Biological Chemistry of the Crimea State Medical University.
, evolutionary biology, and biosystematics
. Using spectral methods, he has demonstrated the existence of changes in the conformation of human immunoglobulins at malignant tumors. He was the first to suggest using the insect proteins and peptides as molecule probes for investigation of the human proteins at norm and pathology. Efetov has established a new scientific approach – monoclonal immunosystematics that makes it possible to evaluate evolutionary relationships between the biological species through studying their proteins with use of monoclonal antibodies
.
K. A. Efetov has described 4 new genera and 10 subgenera of living organisms, discovered and described 25 new biological species inhabiting Japan
, Korea
, Indonesia
, China
, Taiwan
, Vietnam
, Myanmar
(Burma), New Zealand
, India
, Russia
, Kyrgyzstan
, Turkmenistan
, Afghanistan
, Ukraine
and Hungary
. Many times the results of his studies have been represented at international congresses and symposia held in different countries of Europe. In 2004, he initiated and hosted the International Symposium "Biology, Phylogeny, Molecular Biology, and Genetics of Zygaenidae
" at the Crimean State Medical University.
K. A. Efetov is the author of 320 scientific works that include over 20 monographs and 12 patents for inventions. His studies have been quoted 550 times in 200 publications of scientists of 22 countries in 9 languages (including English, Hungarian, Spanish, Italian, German, French, and Japanese). He has trained one Doctor of Science and two Philosophy Doctors; currently (2009) he is supervising the writing of 6 dissertations.
For his achievements in the fields of biology and medicine, K. A. Efetov is awarded with four gold medals: "One Thousand Great Scientists" (Great Britain, 2002), "Outstanding Europeans of the 21st Century" (Great Britain, 2003), "International Scientist of the Year" (Great Britain, 2003), "American Medal of Honor" (USA, 2004). He is represented in the biographical reference books "Contemporary Who’s Who" (USA) and "Outstanding Europeans of the 21st Century" (Great Britain). In honour of K. A. Efetov, scientists of Austria, France, Ukraine, and Russia named 3 biological species (Etroga efetovi Richter, 1994; Zygaenoprocris efetovi Mollet et Tarmann, 2007; Chrysartona efetovi Parshkova, 2007) and a subgenus of living organisms (Efetovia Mollet, 2001).
K. A. Efetov is the Laureate of the State Prize of Republic of Crimea (1996), the Laureate of the Prize of the Council of Ministers of Autonomous Republic of Crimea (2000), the Laureate of the Prize of Autonomous Republic of Crimea (2008). He is awarded with the Honorary Diplomas of the Presidium of the Supreme Council of Autonomous Republic of Crimea (1998), the Council of Ministers of Autonomous Republic of Crimea (1998, 2002), and the Ministry of Public Health of Ukraine (1998).
K. A. Efetov is the member of the editorial boards of the scientific journals "Tavricheskiy Mediko-biologicheskiy Vestnik" (Ukraine) and "Entomologist’s Gazette" (Great Britain), the scientific Readers "Problems, Achievements and Prospects of Development of Life Sciences and Practical Public Health (Transactions of the Crimean State Medical University)" and "The Marine Doctor’s Bulletin".
") devoted to his unusual hypotheses at the crossroads of medicine, art and history. In particular, the author asserts that on Michelangelo
’s frescoes in the Sistine Chapel
there are several "invisible" images: if examined, they radically change the spectator’s ideas about the specific meaning implanted into these frescoes by their creator. Another hypothesis is dedicated to the interpretation of the biblical myth about the creation of woman from Adam’s rib: the author sees parallels between the components of this myth and the biochemical mechanism of the formation of female sex hormones
. These hypotheses did obtain wide response in the Internet and even were used for quizzes in the world championship "What? Where? When?
".
K. A. Efetov published four poetic collections: "Wings’ Stroke", "The Black-and-White Square", "The life of the ‘Bats’" and "The Wells of Memory". He is also the scripter of hymn, the author of flag and the co-author of coat of arms of the Crimea State Medical University
.
Crimea State Medical University named after S. I. Georgievsky
Crimea State Medical University named after S. I. Georgievsky is the institution of higher medical education situated in Simferopol . According to some independent estimations it is one of the most prominent medical schools of Ukraine. The university has 6 faculties and 54 departments...
.
Biography
Efetov was born in Simferopol on July 18, 1958. In 1975, having graduated from school with Gold Medal, he entered the Crimea Medical Institute and graduated from it magna cum laude (with honours) in 1981. After completion of his postgraduate course, in 1986 he became Philosophy Doctor of Medicine having defended his PhD thesis "Stability of Conformation of Immunoglobulins G at Norm and Chronic Lymphoid Leukaemia" (Efetov’s Scientific Adviser was Professor G. V. Troitsky, the Corresponding Member of the Academy of Sciences of Ukraine, the Honored Scientist of Ukraine). In 1986, Efetov was among the founders of the Hybridoma Laboratory at CSMU. Since 1986, he worked as the senior, chief, and then top research scientific researcher at CSMU; since 1992, he has been working as the Head of the Laboratory of Biotechnology. In 1994, he became Doctor of Biological Sciences having defended his doctoral thesis "A Study of Immunoglobulins at Norm and Pathology with Use of Monoclonal Antibodies and Spectral Methods", in which, for the first time, he applied insect peptidePeptide
Peptides are short polymers of amino acid monomers linked by peptide bonds. They are distinguished from proteins on the basis of size, typically containing less than 50 monomer units. The shortest peptides are dipeptides, consisting of two amino acids joined by a single peptide bond...
s for investigation of human protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
s. Since 1995, Efetov is Professor and since 1999, he is the Head of the Department of Biological Chemistry of the Crimea State Medical University.
Scientific Activities
Efetov’s major scientific interests are focused on molecular immunologyImmunology
Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. It deals with the physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders ; the...
, evolutionary biology, and biosystematics
Systematics
Biological systematics is the study of the diversification of terrestrial life, both past and present, and the relationships among living things through time. Relationships are visualized as evolutionary trees...
. Using spectral methods, he has demonstrated the existence of changes in the conformation of human immunoglobulins at malignant tumors. He was the first to suggest using the insect proteins and peptides as molecule probes for investigation of the human proteins at norm and pathology. Efetov has established a new scientific approach – monoclonal immunosystematics that makes it possible to evaluate evolutionary relationships between the biological species through studying their proteins with use of monoclonal antibodies
Monoclonal antibodies
Monoclonal antibodies are monospecific antibodies that are the same because they are made by identical immune cells that are all clones of a unique parent cell....
.
K. A. Efetov has described 4 new genera and 10 subgenera of living organisms, discovered and described 25 new biological species inhabiting Japan
Japan
Japan is an island nation in East Asia. Located in the Pacific Ocean, it lies to the east of the Sea of Japan, China, North Korea, South Korea and Russia, stretching from the Sea of Okhotsk in the north to the East China Sea and Taiwan in the south...
, Korea
Korea
Korea ) is an East Asian geographic region that is currently divided into two separate sovereign states — North Korea and South Korea. Located on the Korean Peninsula, Korea is bordered by the People's Republic of China to the northwest, Russia to the northeast, and is separated from Japan to the...
, Indonesia
Indonesia
Indonesia , officially the Republic of Indonesia , is a country in Southeast Asia and Oceania. Indonesia is an archipelago comprising approximately 13,000 islands. It has 33 provinces with over 238 million people, and is the world's fourth most populous country. Indonesia is a republic, with an...
, China
China
Chinese civilization may refer to:* China for more general discussion of the country.* Chinese culture* Greater China, the transnational community of ethnic Chinese.* History of China* Sinosphere, the area historically affected by Chinese culture...
, Taiwan
Taiwan
Taiwan , also known, especially in the past, as Formosa , is the largest island of the same-named island group of East Asia in the western Pacific Ocean and located off the southeastern coast of mainland China. The island forms over 99% of the current territory of the Republic of China following...
, Vietnam
Vietnam
Vietnam – sometimes spelled Viet Nam , officially the Socialist Republic of Vietnam – is the easternmost country on the Indochina Peninsula in Southeast Asia. It is bordered by China to the north, Laos to the northwest, Cambodia to the southwest, and the South China Sea –...
, Myanmar
Myanmar
Burma , officially the Republic of the Union of Myanmar , is a country in Southeast Asia. Burma is bordered by China on the northeast, Laos on the east, Thailand on the southeast, Bangladesh on the west, India on the northwest, the Bay of Bengal to the southwest, and the Andaman Sea on the south....
(Burma), New Zealand
New Zealand
New Zealand is an island country in the south-western Pacific Ocean comprising two main landmasses and numerous smaller islands. The country is situated some east of Australia across the Tasman Sea, and roughly south of the Pacific island nations of New Caledonia, Fiji, and Tonga...
, India
India
India , officially the Republic of India , is a country in South Asia. It is the seventh-largest country by geographical area, the second-most populous country with over 1.2 billion people, and the most populous democracy in the world...
, Russia
Russia
Russia or , officially known as both Russia and the Russian Federation , is a country in northern Eurasia. It is a federal semi-presidential republic, comprising 83 federal subjects...
, Kyrgyzstan
Kyrgyzstan
Kyrgyzstan , officially the Kyrgyz Republic is one of the world's six independent Turkic states . Located in Central Asia, landlocked and mountainous, Kyrgyzstan is bordered by Kazakhstan to the north, Uzbekistan to the west, Tajikistan to the southwest and China to the east...
, Turkmenistan
Turkmenistan
Turkmenistan , formerly also known as Turkmenia is one of the Turkic states in Central Asia. Until 1991, it was a constituent republic of the Soviet Union, the Turkmen Soviet Socialist Republic . Turkmenistan is one of the six independent Turkic states...
, Afghanistan
Afghanistan
Afghanistan , officially the Islamic Republic of Afghanistan, is a landlocked country located in the centre of Asia, forming South Asia, Central Asia and the Middle East. With a population of about 29 million, it has an area of , making it the 42nd most populous and 41st largest nation in the world...
, Ukraine
Ukraine
Ukraine is a country in Eastern Europe. It has an area of 603,628 km², making it the second largest contiguous country on the European continent, after Russia...
and Hungary
Hungary
Hungary , officially the Republic of Hungary , is a landlocked country in Central Europe. It is situated in the Carpathian Basin and is bordered by Slovakia to the north, Ukraine and Romania to the east, Serbia and Croatia to the south, Slovenia to the southwest and Austria to the west. The...
. Many times the results of his studies have been represented at international congresses and symposia held in different countries of Europe. In 2004, he initiated and hosted the International Symposium "Biology, Phylogeny, Molecular Biology, and Genetics of Zygaenidae
Zygaenidae
The Zygaenidae moths are a family of Lepidoptera. The majority of zygaenids are tropical, but they are nevertheless quite well represented in temperate regions. There are about 1000 species. Various species are commonly known as Burnet or Forester moths, often qualified by the number of spots,...
" at the Crimean State Medical University.
K. A. Efetov is the author of 320 scientific works that include over 20 monographs and 12 patents for inventions. His studies have been quoted 550 times in 200 publications of scientists of 22 countries in 9 languages (including English, Hungarian, Spanish, Italian, German, French, and Japanese). He has trained one Doctor of Science and two Philosophy Doctors; currently (2009) he is supervising the writing of 6 dissertations.
Awards and Titles
K. A. Efetov is the Academician of the Crimean Academy of Science (since 2002), the Honored Scientist of Ukraine (since 2004), the Chairman of the Crimean Biochemical Society (since 2006), the Member of the Central Council of the Ukrainian Biochemical Society (since 2006), the Vice President of the Junior Academy of Science of Crimea (since 1997), the Member of the Council of the European Lepidopterological Society (2005–2009), the Member of the Union of the Russian, Ukrainian and Belorussian Writers of Autonomous Republic of Crimea.For his achievements in the fields of biology and medicine, K. A. Efetov is awarded with four gold medals: "One Thousand Great Scientists" (Great Britain, 2002), "Outstanding Europeans of the 21st Century" (Great Britain, 2003), "International Scientist of the Year" (Great Britain, 2003), "American Medal of Honor" (USA, 2004). He is represented in the biographical reference books "Contemporary Who’s Who" (USA) and "Outstanding Europeans of the 21st Century" (Great Britain). In honour of K. A. Efetov, scientists of Austria, France, Ukraine, and Russia named 3 biological species (Etroga efetovi Richter, 1994; Zygaenoprocris efetovi Mollet et Tarmann, 2007; Chrysartona efetovi Parshkova, 2007) and a subgenus of living organisms (Efetovia Mollet, 2001).
K. A. Efetov is the Laureate of the State Prize of Republic of Crimea (1996), the Laureate of the Prize of the Council of Ministers of Autonomous Republic of Crimea (2000), the Laureate of the Prize of Autonomous Republic of Crimea (2008). He is awarded with the Honorary Diplomas of the Presidium of the Supreme Council of Autonomous Republic of Crimea (1998), the Council of Ministers of Autonomous Republic of Crimea (1998, 2002), and the Ministry of Public Health of Ukraine (1998).
K. A. Efetov is the member of the editorial boards of the scientific journals "Tavricheskiy Mediko-biologicheskiy Vestnik" (Ukraine) and "Entomologist’s Gazette" (Great Britain), the scientific Readers "Problems, Achievements and Prospects of Development of Life Sciences and Practical Public Health (Transactions of the Crimean State Medical University)" and "The Marine Doctor’s Bulletin".
Interesting facts
In recent times, K. A. Efetov has published several books ("A Shocking Secret of the Sistine Chapel", "Das Schockierende Geheimnis der Sixtinischen Kapelle" and "Old Testament’s Secret of the Rib of Adam") and articles (in the journals "Chemistry and Life", "Asclepius", "Discoveries and Hypotheses", "KontaktoKontakto
Kontakto is a magazine in Esperanto published by TEJO and supported by Universal Esperanto Association . The magazine has readers in about 90 countries of the world. It started in 1963 though a proposal of the UEA committee by Humphrey Tonkin, who became its first editor in chief and who provided a...
") devoted to his unusual hypotheses at the crossroads of medicine, art and history. In particular, the author asserts that on Michelangelo
Michelangelo
Michelangelo di Lodovico Buonarroti Simoni , commonly known as Michelangelo, was an Italian Renaissance painter, sculptor, architect, poet, and engineer who exerted an unparalleled influence on the development of Western art...
’s frescoes in the Sistine Chapel
Sistine Chapel
Sistine Chapel is the best-known chapel in the Apostolic Palace, the official residence of the Pope in Vatican City. It is famous for its architecture and its decoration that was frescoed throughout by Renaissance artists including Michelangelo, Sandro Botticelli, Pietro Perugino, Pinturicchio...
there are several "invisible" images: if examined, they radically change the spectator’s ideas about the specific meaning implanted into these frescoes by their creator. Another hypothesis is dedicated to the interpretation of the biblical myth about the creation of woman from Adam’s rib: the author sees parallels between the components of this myth and the biochemical mechanism of the formation of female sex hormones
Sex steroid
Sex steroids, also known as gonadal steroids, are steroid hormones that interact with vertebrate androgen or estrogen receptors. Their effects are mediated by slow genomic mechanisms through nuclear receptors as well as by fast nongenomic mechanisms through membrane-associated receptors and...
. These hypotheses did obtain wide response in the Internet and even were used for quizzes in the world championship "What? Where? When?
What? Where? When?
What? Where? When? is an intellectual game show well known in Russian-language media and other CIS states. It is produced for television by TV Igra on the Russian Channel One and also exists as a competitive game played in clubs organized by the ....
".
K. A. Efetov published four poetic collections: "Wings’ Stroke", "The Black-and-White Square", "The life of the ‘Bats’" and "The Wells of Memory". He is also the scripter of hymn, the author of flag and the co-author of coat of arms of the Crimea State Medical University
Crimea State Medical University named after S. I. Georgievsky
Crimea State Medical University named after S. I. Georgievsky is the institution of higher medical education situated in Simferopol . According to some independent estimations it is one of the most prominent medical schools of Ukraine. The university has 6 faculties and 54 departments...
.