Alleles	B*6701
Structure (See HLA-B HLA-B HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex... )
Symbol(s) Human Genome Organisation The Human Genome Organisation is an organization involved in the Human Genome Project, a project about mapping the human genome. HUGO was established in 1989 as an international organization, primarily to foster collaboration between genome scientists around the world...	HLA-B
EBI-HLA European Bioinformatics Institute The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory...	B*6701
Locus Locus (genetics) In the fields of genetics and genetic computation, a locus is the specific location of a gene or DNA sequence on a chromosome. A variant of the DNA sequence at a given locus is called an allele. The ordered list of loci known for a particular genome is called a genetic map...	chr.6 Chromosome 6 (human) Chromosome 6 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 6 spans more than 170 million base pairs and represents between 5.5 and 6% of the total DNA in cells...  6p21.31

HLA-B67 (B67) is an HLA

Human leukocyte antigen

The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...

-B

HLA-B

HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex...

 serotype

Serotype

Serotype or serovar refers to distinct variations within a subspecies of bacteria or viruses. These microorganisms, viruses, or cells are classified together based on their cell surface antigens...

. The serotype identifies the more common HLA-B*67 gene products. B67 is region specific recombinant haplotype formed by the gene conversion of B*39

HLA-B39

HLA-B39 is an HLA-B serotype. The serotype identifies the more common HLA-B*39 gene products.B39 is a split antigen of the broad antigen B16, and is a sister type of B38. B39 is most commonly found on the west pacific rim, in Japan and highest frequency in the new world...

, an allele common along the Northwest Pacific Rim (Taiwan, Japan, Korea, Coastal Siberia), and B7

HLA-B7

HLA-B7 is an HLA-B serotype. The serotype identifies the more common HLA-B*07 gene products. B7, previously HL-A7, was one of the first 'HL-A' antigens recognized, largely because of the frequency of B*0702 in Northern and Western Europe and the United States...

, B22

HLA-B22

HLA-B22 is an HLA - B serotype. B22 is a broad antigen serotype that recognizes the B54, B55, and B56 split antigen serotypes....

, or B27

HLA-B27

Human Leukocyte Antigen B27 is a class I surface antigen encoded by the B locus in the major histocompatibility complex on chromosome 6 and presents antigenic peptides to T cells...

. (For terminology help see: HLA-serotype tutorial)

Serotype

B67 Serotype recognition of the B*67 allele-group gene products

B*67	B67	Other	Sample
allele	%	%	size (N)
6701	32	62	81

By allele

Regions of higher B*6701 frequency

Japan
Taiwan
Heilongjiang province, China (Harbin city)
Beijing China
Shandong peninsula

HLA B*6701 frequencies

		freq
ref.	Population	(%)
	Osaka Region (Japan)	2.6
	Hakka (Taiwan Taiwan Taiwan , also known, especially in the past, as Formosa , is the largest island of the same-named island group of East Asia in the western Pacific Ocean and located off the southeastern coast of mainland China. The island forms over 99% of the current territory of the Republic of China following... )	1.8
	Japan (5)	1.7
	Harbin Man (China)	1.7
	Beijing (China)	1.5
	Linqu (Shandong, China)	1.1
	Siraya (Taiwan)	1.0
	Portugal South	1.0
	Oold (Mongolia)	1.0
	American Samoa	1.0
	Pazeh (Taiwan)	0.9
	South Korea (3)	0.9
	N. Korean (Harbin,China)	0.8
	Arratia Basque (Spain)	0.6
	Tarialan Khoton (Mongolia)	0.6
	Shanghai (China)	0.6
	Natal Zulu (South African)	0.5
	Yunnan Han (China)	0.5
	Turkey	0.4
	Southern Han (China)	0.4
	Tuva (Russia)	0.3
	Chinese (Hong Kong , China)	0.1