Aqua Tofana
Encyclopedia
Aqua Tofana was a strong poison
Poison
In the context of biology, poisons are substances that can cause disturbances to organisms, usually by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by an organism....

 that was reputedly widely used in Naples
Naples
Naples is a city in Southern Italy, situated on the country's west coast by the Gulf of Naples. Lying between two notable volcanic regions, Mount Vesuvius and the Phlegraean Fields, it is the capital of the region of Campania and of the province of Naples...

 and Rome
Rome
Rome is the capital of Italy and the country's largest and most populated city and comune, with over 2.7 million residents in . The city is located in the central-western portion of the Italian Peninsula, on the Tiber River within the Lazio region of Italy.Rome's history spans two and a half...

, Italy
Italy
Italy , officially the Italian Republic languages]] under the European Charter for Regional or Minority Languages. In each of these, Italy's official name is as follows:;;;;;;;;), is a unitary parliamentary republic in South-Central Europe. To the north it borders France, Switzerland, Austria and...

. During the early 17th century Giulia Tofana
Giulia Tofana
Giulia Tofana or Toffana was an Italian professional poisoner. She was famous for selling poison to women who wanted to murder their husbands. She was the inventor of the famous poison Aqua Tofana, which is named after her....

, or Tofania, an infamous lady from Palermo
Palermo
Palermo is a city in Southern Italy, the capital of both the autonomous region of Sicily and the Province of Palermo. The city is noted for its history, culture, architecture and gastronomy, playing an important role throughout much of its existence; it is over 2,700 years old...

, made a good business for over fifty years selling her large production (she employed her daughter and several other lady helpers) of Aqua Tofana to would-be widows. The product was sold to lady clients, accompanied by instructions for its use.

Aqua Tofana (literally meaning "Tofana water") was either the creation of Giulia Tofana
Giulia Tofana
Giulia Tofana or Toffana was an Italian professional poisoner. She was famous for selling poison to women who wanted to murder their husbands. She was the inventor of the famous poison Aqua Tofana, which is named after her....

 or an older recipe that had been refined by Tofana and her daughter, Girolama Spera, around 1650 in Rome. The 'tradename' "Manna di San Nicola", i.e. "Manna of St. Nicholas of Bari
Bari
Bari is the capital city of the province of Bari and of the Apulia region, on the Adriatic Sea, in Italy. It is the second most important economic centre of mainland Southern Italy after Naples, and is well known as a port and university city, as well as the city of Saint Nicholas...

" might have been a marketing device intended to divert the authorities, since the poison was openly sold both as a cosmetic and a devotionary object in vials that included a picture of St. Nicholas. Some of her customers claimed to have used it for its advertised purposes and only caused deaths accidentally. Over 600 victims are known to have died from this poison, mostly husbands of unhappy spouses. Tofana was arrested and confessed to producing the poison, and she implicated that a number of her clients knew exactly what they were buying. There was much disquiet throughout Italy and many of her clients fled, while others were strangled in prison, and indeed many were publicly executed. Between 1666 and 1676 the Marchioness de Brinvilliers
Marie-Madeleine-Marguerite d'Aubray, Marquise de Brinvilliers
Marie-Madeleine-Marguerite d'Aubray, Marquise de Brinvilliers was a French serial killer.-Crimes:Marie-Madeleine-Marguerite d'Aubray conspired with her lover, army captain Godin de Sainte-Croix to poison her father Antonine Dreux d'Aubray in 1666 and two of her brothers, Antoine d'Aubray and...

 poisoned her father, two brothers, amongst others, and was executed on July 16, 1676.

The ingredients of the mixture are basically known but not how they were blended. Aqua Tofana contained mostly arsenic
Arsenic
Arsenic is a chemical element with the symbol As, atomic number 33 and relative atomic mass 74.92. Arsenic occurs in many minerals, usually in conjunction with sulfur and metals, and also as a pure elemental crystal. It was first documented by Albertus Magnus in 1250.Arsenic is a metalloid...

 and lead
Lead
Lead is a main-group element in the carbon group with the symbol Pb and atomic number 82. Lead is a soft, malleable poor metal. It is also counted as one of the heavy metals. Metallic lead has a bluish-white color after being freshly cut, but it soon tarnishes to a dull grayish color when exposed...

 and possibly belladonna. It was a colorless, tasteless liquid and so easily mixed with water or wine to be served during meals.

The legend that Mozart
Wolfgang Amadeus Mozart
Wolfgang Amadeus Mozart , baptismal name Johannes Chrysostomus Wolfgangus Theophilus Mozart , was a prolific and influential composer of the Classical era. He composed over 600 works, many acknowledged as pinnacles of symphonic, concertante, chamber, piano, operatic, and choral music...

 (1756—1791) might have been poisoned using Aqua Tofana is completely unsubstantiated.

Tofana is in many sources confused with Hieronyma Spara, "La Spara", a woman with a similar profession in Italy about the same time. Probably this is another name of the 'astroliga della Lungara'.

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