Sam Gandy
Encyclopedia
Dr. Samuel E. Gandy is an international expert in the metabolism of the sticky substance called amyloid
Amyloid
Amyloids are insoluble fibrous protein aggregates sharing specific structural traits. Abnormal accumulation of amyloid in organs may lead to amyloidosis, and may play a role in various neurodegenerative diseases.-Definition:...

 that clogs the brain in patients with Alzheimer's. He currently serves on the Research Consortium of Cure Alzheimer's Fund
Cure Alzheimer's Fund
Cure Alzheimer's Fund, a 'doing business as' name for the Alzheimer's Disease Research Foundation, is a 501 public charity established to provide funding for targeted research into the causes of Alzheimer’s disease.-Mission:...

.

Research

In 1989, Gandy and his team discovered the first drugs that could lower formation of amyloid. Gandy has written more than 150 original papers, chapters and reviews on this topic. He has received continuous National Institutes of Health
National Institutes of Health
The National Institutes of Health are an agency of the United States Department of Health and Human Services and are the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation...

 (NIH) funding for his research on amyloid metabolism since 1986.

Biography

Gandy is the Mount Sinai Professor of Alzheimer's Disease
Alzheimer's disease
Alzheimer's disease also known in medical literature as Alzheimer disease is the most common form of dementia. There is no cure for the disease, which worsens as it progresses, and eventually leads to death...

 Research, Professor of Neurology
Neurology
Neurology is a medical specialty dealing with disorders of the nervous system. Specifically, it deals with the diagnosis and treatment of all categories of disease involving the central, peripheral, and autonomic nervous systems, including their coverings, blood vessels, and all effector tissue,...

 and Psychiatry
Psychiatry
Psychiatry is the medical specialty devoted to the study and treatment of mental disorders. These mental disorders include various affective, behavioural, cognitive and perceptual abnormalities...

, Associate Director of the Mount Sinai Medical Center Alzheimer's Disease Research Center in New York City
New York City
New York is the most populous city in the United States and the center of the New York Metropolitan Area, one of the most populous metropolitan areas in the world. New York exerts a significant impact upon global commerce, finance, media, art, fashion, research, technology, education, and...

, and Chairman Emeritus of the National Medical and Scientific Advisory Council of the Alzheimer's Association
Alzheimer's Association
The Alzheimer's Association, incorporated on April 10, 1980 as the Alzheimer’s Disease and Related Disorders Association, Inc., is a non-profit American voluntary health organization which focuses on care, support and research for Alzheimer's disease....

. He received both his MD and PhD at the Medical University of South Carolina
Medical University of South Carolina
The Medical University of South Carolina opened in Charleston, South Carolina in 1824 as a small private college for the training of physicians. It is one of the oldest continually operating school of medicine in the United States and the oldest in the Deep South...

.

He did his postgraduate work at the Columbia University College of Physicians & Surgeons and Cornell University Medical College. Gandy completed his post-doctorate at Rockefeller University
Rockefeller University
The Rockefeller University is a private university offering postgraduate and postdoctoral education. It has a strong concentration in the biological sciences. It is also known for producing numerous Nobel laureates...

, where he was appointed assistant professor in the laboratory of Paul Greengard
Paul Greengard
Paul Greengard is an American neuroscientist best known for his work on the molecular and cellular function of neurons. In 2000, Greengard, Arvid Carlsson and Eric Kandel were awarded the Nobel Prize for Physiology or Medicine for their discoveries concerning signal transduction in the nervous...

, 2000 Laureate of the Nobel Prize in Physiology or Medicine
Nobel Prize in Physiology or Medicine
The Nobel Prize in Physiology or Medicine administered by the Nobel Foundation, is awarded once a year for outstanding discoveries in the field of life science and medicine. It is one of five Nobel Prizes established in 1895 by Swedish chemist Alfred Nobel, the inventor of dynamite, in his will...

.

Gandy was appointed associate professor of neurology and neurosciences at Cornell University Medical College in 1992. In 1997, he moved to New York University
New York University
New York University is a private, nonsectarian research university based in New York City. NYU's main campus is situated in the Greenwich Village section of Manhattan...

 where he served as professor of psychiatry and cell biology
Cell biology
Cell biology is a scientific discipline that studies cells – their physiological properties, their structure, the organelles they contain, interactions with their environment, their life cycle, division and death. This is done both on a microscopic and molecular level...

 until his appointment as Paul C. Brucker, M.D., Professor of Neuroscience at Jefferson Medical College and Director of the Farber Institute for Neurosciences in 2001. In July, 2007, he assumed his current post as Sinai Professor of Alzheimer’s Disease Research at the Mount Sinai School of Medicine. He is also a member of the Research Consortium of the Cure Alzheimer's Fund
Cure Alzheimer's Fund
Cure Alzheimer's Fund, a 'doing business as' name for the Alzheimer's Disease Research Foundation, is a 501 public charity established to provide funding for targeted research into the causes of Alzheimer’s disease.-Mission:...

.

In 2009, Gandy was featured with other prominent research scientists as one of GQ's "Rockstars of Science" and featured in the international documentary
Documentary
A documentary is a creative work of non-fiction, including:* Documentary film, including television* Radio documentary* Documentary photographyRelated terms include:...

 film I Remember Better When I Paint
I Remember Better When I Paint
I Remember Better When I Paint is a 2009 feature length international documentary film about the positive impact of art and other creative therapies in people with Alzheimer's disease and how these approaches can change the way the disease is viewed by society...

which examines the phenomenon of how pathways to emotional parts of the brain of those with Alzheimer's are awakened through the creative arts. Gandy has appeared numerous times speaking about Alzheimer's in major news media including PBS Newshour.

External links

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