SIN3A
Encyclopedia
Paired amphipathic helix protein Sin3a is a protein
that in humans is encoded by the SIN3A gene
.
with HDAC9
, OGT
, RBBP7
, RBBP4
, Host cell factor C1
, MXD1
, IKZF1
, Nuclear receptor co-repressor 2
, SAP130
, KLF11
, Methyl-CpG-binding domain protein 2
, HDAC1
, Histone deacetylase 2
, Zinc finger and BTB domain-containing protein 16
, SUDS3
, SAP30
, PHF12
, SMARCA2
, ING1
, MNT
, SMARCC1
, SMARCA4
, TAL1
, Promyelocytic leukemia protein
, CABIN1
and HBP1
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the SIN3A gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
SIN3A has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with HDAC9
HDAC9
Histone deacetylase 9 is an enzyme that in humans is encoded by the HDAC9 gene.-Interactions:HDAC9 has been shown to interact with SIN3A, Nuclear receptor co-repressor 1, CBX5, HDAC3, Myocyte-specific enhancer factor 2A and SUV39H1....
, OGT
OGT (gene)
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit is an enzyme that in humans is encoded by the OGT gene.-Interactions:OGT has been shown to interact with Host cell factor C1 and SIN3A.-Further reading:...
, RBBP7
RBBP7
Histone-binding protein RBBP7 is a protein that in humans is encoded by the RBBP7 gene.-Interactions:RBBP7 has been shown to interact with HDAC1, MTA2, SIN3A, Retinoblastoma protein, SAP30, GATAD2B and BRCA1.-Further reading:...
, RBBP4
RBBP4
Histone-binding protein RBBP4 is a protein that in humans is encoded by the RBBP4 gene.-Interactions:RBBP4 has been shown to interact with HDAC1, Histone deacetylase 2, SIN3A, Retinoblastoma protein, SAP30, CREB-binding protein, GATAD2B, BRCA1, MTA2 and HDAC3.-Further reading:...
, Host cell factor C1
Host cell factor C1
Host cell factor is a protein that in humans is encoded by the HCFC1 gene.-Interactions:Host cell factor C1 has been shown to interact with HDAC1, Histone deacetylase 2, OGT, SIN3A, SUDS3, ZBTB17, Sp1 transcription factor, MLL, PPP1CA, POU2F1, PDCD2, WDR5, CREB3 and GABPA.-Further reading:...
, MXD1
MXD1
MAD protein is a protein that in humans is encoded by the MXD1 gene.-Interactions:MXD1 has been shown to interact with Histone deacetylase 2, SMC3, MLX, SIN3A and MAX.-Further reading:...
, IKZF1
IKZF1
DNA-binding protein Ikaros also known as Ikaros family zinc finger protein 1 is a protein that in humans is encoded by the IKZF1 gene. Ikaros displays crucial functions in the hematopoietic system and its loss of function has been linked to the development of lymphoid leukemia...
, Nuclear receptor co-repressor 2
Nuclear receptor co-repressor 2
The nuclear receptor co-repressor 2 is a transcriptional coregulatory protein that contains several nuclear receptor-interacting domains. In addition, NCOR2 appears to recruit histone deacetylases to DNA promoter regions. Hence NCOR2 assists nuclear receptors in the down regulation of target...
, SAP130
SAP130
Histone deacetylase complex subunit SAP130 is an enzyme that in humans is encoded by the SAP130 gene.-Interactions:SAP130 has been shown to interact with CSN1S1, SIN3A, Myc, Von Hippel-Lindau tumor suppressor and CUL2.-Further reading:...
, KLF11
KLF11
Krueppel-like factor 11 is a protein that in humans is encoded by the KLF11 gene....
, Methyl-CpG-binding domain protein 2
Methyl-CpG-binding domain protein 2
Methyl-CpG-binding domain protein 2 is a protein that in humans is encoded by the MBD2 gene.-Interactions:Methyl-CpG-binding domain protein 2 has been shown to interact with HDAC1, Histone deacetylase 2, SIN3A, MIZF, MBD3 and GATAD2B....
, HDAC1
HDAC1
Histone deacetylase 1 is an enzyme that in humans is encoded by the HDAC1 gene.-Interactions:HDAC1 has been shown to interact with RAD9A, DNMT3L, MTA1, FKBP3, CDC20, CDH1, Host cell factor C1, BUB3, Nuclear receptor co-repressor 2, IKZF1, Prohibitin, EVI1, DDX5, DNMT3A, Mothers against...
, Histone deacetylase 2
Histone deacetylase 2
Histone deacetylase 2 is an enzyme that in humans is encoded by the HDAC2 gene.-Interactions:Histone deacetylase 2 has been shown to interact with CHD3, MTA1, FKBP3, CHD4, RCOR1, Retinoblastoma protein, CDC20, RBBP4, CDH1, EED, GTF2I, Host cell factor C1, PHF21A, BUB3, MXD1, HDAC10, RELA, Sp3...
, Zinc finger and BTB domain-containing protein 16
Zinc finger and BTB domain-containing protein 16
Zinc finger and BTB domain-containing protein 16 is a protein that in humans is encoded by the ZBTB16 gene.-Function:This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the...
, SUDS3
SUDS3
Sin3 histone deacetylase corepressor complex component SDS3 is an enzyme that in humans is encoded by the SUDS3 gene.-Interactions:SUDS3 has been shown to interact with HDAC1, Host cell factor C1, SIN3B and SIN3A.-Further reading:...
, SAP30
SAP30
Sin3A-associated protein, 30kDa, also known as SAP30, is a protein which in humans is encoded by the SAP30 gene.- Function :Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes...
, PHF12
PHF12
PHD finger protein 12 is a protein that in humans is encoded by the PHF12 gene.-Further reading:...
, SMARCA2
SMARCA2
Probable global transcription activator SNF2L2 is a protein that in humans is encoded by the SMARCA2 gene.-Interactions:SMARCA2 has been shown to interact with SS18, ACTL6A, SIN3A, POLR2A, Prohibitin, SMARCC1, CEBPB, SMARCB1 and ARID1B....
, ING1
ING1
Inhibitor of growth protein 1 is a protein that in humans is encoded by the ING1 gene.-Location on Chromosome 13:ING1 is located near the following genes on Chromosome 13*CARKD Carbohydrate Kinase Domain-Containing Protein...
, MNT
MNT (gene)
Max-binding protein MNT is a protein that in humans is encoded by the MNT gene.-Interactions:MNT has been shown to interact with MLX, SIN3A and MAX....
, SMARCC1
SMARCC1
SWI/SNF complex subunit SMARCC1 is a protein that in humans is encoded by the SMARCC1 gene.-Interactions:SMARCC1 has been shown to interact with BAZ1B, SIN3A, SMARCA2, ING1, SMARCB1 and SMARCA4.-External links:...
, SMARCA4
SMARCA4
Transcription activator BRG1 also known as ATP-dependent helicase SMARCA4 is a protein that in humans is encoded by the SMARCA4 gene.- Function :...
, TAL1
TAL1
T-cell acute lymphocytic leukemia protein 1 is a protein that in humans is encoded by the TAL1 gene.The protein encoded by TAL1 is a basic-helix-loop-helix transcription factor.-Interactions:...
, Promyelocytic leukemia protein
Promyelocytic leukemia protein
Probable transcription factor PML is a tumor suppressor protein that in humans is encoded by the PML gene.-Interactions:Promyelocytic leukemia protein has been shown to interact with Retinoic acid receptor alpha, HDAC1, Nerve Growth factor IB, SKI protein, Zinc finger and BTB domain-containing...
, CABIN1
CABIN1
Calcineurin-binding protein cabin-1 is a protein that in humans is encoded by the CABIN1 gene.-Interactions:CABIN1 has been shown to interact with MEF2B, MEF2D, Amphiphysin and SIN3A.-Further reading:...
and HBP1
HBP1
HMG-box transcription factor 1, also known as HBP1, is a human protein.-Interactions:HBP1 has been shown to interact with SIN3A and Retinoblastoma protein.-Further reading:...
.