SAP130
Encyclopedia
Histone deacetylase complex subunit SAP130 is an enzyme
that in humans is encoded by the SAP130 gene
.
with CSN1S1
, SIN3A
, Myc
, Von Hippel-Lindau tumor suppressor
and CUL2
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the SAP130 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
SAP130 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with CSN1S1
CSN1S1
Alpha-S1-casein is a protein that in humans is encoded by the CSN1S1 gene.-Further reading:...
, SIN3A
SIN3A
Paired amphipathic helix protein Sin3a is a protein that in humans is encoded by the SIN3A gene.-Interactions:SIN3A has been shown to interact with HDAC9, OGT, RBBP7, RBBP4, Host cell factor C1, MXD1, IKZF1, Nuclear receptor co-repressor 2, SAP130, KLF11, Methyl-CpG-binding domain protein 2, HDAC1,...
, Myc
Myc
Myc is a regulator gene that codes for a transcription factor. In the human genome, Myc is located on chromosome 8 and is believed to regulate expression of 15% of all genes through binding on Enhancer Box sequences and recruiting histone acetyltransferases...
, Von Hippel-Lindau tumor suppressor
Von Hippel-Lindau tumor suppressor
The Von Hippel–Lindau tumor suppressor also known as pVHL is a protein that in humans is encoded by the VHL gene. Mutations of the VHL gene are associated with Von Hippel–Lindau disease....
and CUL2
CUL2
Cullin-2 is a protein that in humans is encoded by the CUL2 gene.-Interactions:CUL2 has been shown to interact with DCUN1D1, SAP130, CAND1, RBX1, TCEB2 and Von Hippel-Lindau tumor suppressor.-Further reading:...
.