Ruggero Oddi was an Italian physiologist and anatomist who was a native of Perugia

Perugia

Perugia is the capital city of the region of Umbria in central Italy, near the River Tiber, and the capital of the province of Perugia. The city is located about north of Rome. It covers a high hilltop and part of the valleys around the area....

. He studied medicine at Perugia, Bologna

Bologna

Bologna is the capital city of Emilia-Romagna, in the Po Valley of Northern Italy. The city lies between the Po River and the Apennine Mountains, more specifically, between the Reno River and the Savena River. Bologna is a lively and cosmopolitan Italian college city, with spectacular history,...

 and Florence

Florence

Florence is the capital city of the Italian region of Tuscany and of the province of Florence. It is the most populous city in Tuscany, with approximately 370,000 inhabitants, expanding to over 1.5 million in the metropolitan area....

, and in 1894 was appointed head of the Physiology Institute at the University of Genoa

University of Genoa

The University of Genoa is one of the largest universities in Italy.Located in Liguria on the Italian Riviera, the university was founded in 1471. It currently has about 40,000 students, 1,800 teaching and research staff and about 1,580 administrative staff.- Campus :The University of Genoa is...

. In 1900 he was relieved of his position at Genoa because of narcotic

Narcotic

The term narcotic originally referred medically to any psychoactive compound with any sleep-inducing properties. In the United States of America it has since become associated with opioids, commonly morphine and heroin and their derivatives, such as hydrocodone. The term is, today, imprecisely...

s usage and fiscal improprieties. Later, he sought employment as a doctor with the Belgian

Belgium

Belgium , officially the Kingdom of Belgium, is a federal state in Western Europe. It is a founding member of the European Union and hosts the EU's headquarters, and those of several other major international organisations such as NATO.Belgium is also a member of, or affiliated to, many...

 colonial medical service, and spent some time working in the Belgian Congo

Belgian Congo

The Belgian Congo was the formal title of present-day Democratic Republic of the Congo between King Leopold II's formal relinquishment of his personal control over the state to Belgium on 15 November 1908, and Congolese independence on 30 June 1960.-Congo Free State, 1884–1908:Until the latter...

. Oddi died on March 22, 1913 in Tunis

Tunis

Tunis is the capital of both the Tunisian Republic and the Tunis Governorate. It is Tunisia's largest city, with a population of 728,453 as of 2004; the greater metropolitan area holds some 2,412,500 inhabitants....

, Tunisia

Tunisia

Tunisia , officially the Tunisian RepublicThe long name of Tunisia in other languages used in the country is: , is the northernmost country in Africa. It is a Maghreb country and is bordered by Algeria to the west, Libya to the southeast, and the Mediterranean Sea to the north and east. Its area...

.

While still a student, Oddi described a small group of circular and longitudinal muscle fibers that wrapped around the end of the bile

Bile duct

A bile duct is any of a number of long tube-like structures that carry bile.Bile, required for the digestion of food, is excreted by the liver into passages that carry bile toward the hepatic duct, which joins with the cystic duct to form the common bile duct, which opens into the intestine.The...

 and pancreatic

Pancreas

The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as a digestive organ, secreting pancreatic juice containing digestive enzymes that assist...

 ducts. This structure was later to be known as the eponymous Sphincter of Oddi

Sphincter of Oddi

The sphincter of ampulla or sphincter of Oddi is a muscular valve that controls the flow of digestive juices through the ampulla of Vater into the second part of the duodenum. It is named after Ruggero Oddi...

. Oddi was not the original discoverer of the sphincter

Sphincter

A sphincter is an anatomical structure, or a circular muscle, that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning...

; English physician Francis Glisson

Francis Glisson

Francis Glisson was a British physician, anatomist, and writer on medical subjects. He did important work on the anatomy of the liver, and he wrote an early pediatric text on rickets...

 initially identified it two centuries earlier. However, it was Oddi who was first able to characterize its physiological properties.

Inflammation of the junction of the duodenum

Duodenum

The duodenum is the first section of the small intestine in most higher vertebrates, including mammals, reptiles, and birds. In fish, the divisions of the small intestine are not as clear and the terms anterior intestine or proximal intestine may be used instead of duodenum...

 and common bile duct

Common bile duct

The common bile duct is a tube-like anatomic structure in the human gastrointestinal tract. It is formed by the union of the common hepatic duct and the cystic duct . It is later joined by the pancreatic duct to form the ampulla of Vater...

at the Sphincter of Oddi is referred to as odditis.