Neurobioengineering
Encyclopedia
In 1995, professor Massimo Grattarola
Massimo Grattarola
Massimo Grattarola was an Italian born multidisciplinary engineer & scientist who pioneered the fields of bioelectronics and neurobioengineering , who established Europe's first Neuroengineering research facility in the mid-1990s.- Founder of Bioelectronics in Italy :Massimo Grattarola thrived at...

 of the Biophysics
Biophysics
Biophysics is an interdisciplinary science that uses the methods of physical science to study biological systems. Studies included under the branches of biophysics span all levels of biological organization, from the molecular scale to whole organisms and ecosystems...

 and Electrical Engineering Department (DIBE) at the University of Genova, in Genova
Génova
Génova may refer to:* Spanish spelling of the city of Genoa, Italy* Génova, Quindío, a municipality in the department of Quindío, Colombia* Génova, Quetzaltenango, a municipality in the department of Quetzaltenango, Guatemala...

, Italy
Italy
Italy , officially the Italian Republic languages]] under the European Charter for Regional or Minority Languages. In each of these, Italy's official name is as follows:;;;;;;;;), is a unitary parliamentary republic in South-Central Europe. To the north it borders France, Switzerland, Austria and...

, created an undergraduate and graduate program named neurobioengineering (also referred to as neuroengineering). The program was designed to amalgamate anthropomorphic robotics, artificial intelligence, bioelectronics
Bioelectronics
Bioelectronics is a recently coined term for a field of research that works to establish a synergy between electronics and biology. One of the main forums for information about the field is the Elsevier journal Biosensors and Bioelectronics, published since 1990...

, electrical engineering
Electrical engineering
Electrical engineering is a field of engineering that generally deals with the study and application of electricity, electronics and electromagnetism. The field first became an identifiable occupation in the late nineteenth century after commercialization of the electric telegraph and electrical...

, molecular biology
Molecular biology
Molecular biology is the branch of biology that deals with the molecular basis of biological activity. This field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry...

, physics
Physics
Physics is a natural science that involves the study of matter and its motion through spacetime, along with related concepts such as energy and force. More broadly, it is the general analysis of nature, conducted in order to understand how the universe behaves.Physics is one of the oldest academic...

, and medicine
Medicine
Medicine is the science and art of healing. It encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness....

, into a single program with the aim of developing advanced bio-compatible neuro-prosthetic implants
Implant (medicine)
An implant is a medical device manufactured to replace a missing biological structure, support a damaged biological structure, or enhance an existing biological structure. Medical implants are man-made devices, in contrast to a transplant, which is a transplanted biomedical tissue...

 (man-machine interfacing) for a variety applications (e.g. nervous system interaction with artificial limbs, central and peripheral nervous system implants, directional neural grafting (neural engineering
Neural engineering
Neural engineering is a discipline within biomedical engineering that uses engineering techniques to understand, repair, replace, enhance, or otherwise exploit the properties of neural systems...

), electron harvesting from biological processes to power implanted devices, neural arrays cultured on CMOS sensors, etc).

Neurobioengineering deals with the study and application of bio-compatible neuro-prosthetic implants, neural sensors and interfaces with the nervous system.

The goal of that branch is to develop a bio-artificial brain of cultured neurons capable of replicating human behaviour in an artificial robotic system. The European Union F.E.T. funded the neurobioengineering department to pursue this ambitious project.

History

The neurobioengineering program spawned numerous journal publications by the departmental scientific pioneers (Dr. Marco Bove, Dr. Sergio Martinoia, Dr. Renato Zaccaria, and many others) and a university course textbook Bioelectronics, MOSFETS, Biosensors and Neurons published by Massimo Grattarola. Members of the department were collaborating with researchers throughout the European Union
European Union
The European Union is an economic and political union of 27 independent member states which are located primarily in Europe. The EU traces its origins from the European Coal and Steel Community and the European Economic Community , formed by six countries in 1958...

, Japan
Japan
Japan is an island nation in East Asia. Located in the Pacific Ocean, it lies to the east of the Sea of Japan, China, North Korea, South Korea and Russia, stretching from the Sea of Okhotsk in the north to the East China Sea and Taiwan in the south...

 and North America
North America
North America is a continent wholly within the Northern Hemisphere and almost wholly within the Western Hemisphere. It is also considered a northern subcontinent of the Americas...

. Students from throughout the European Union
European Union
The European Union is an economic and political union of 27 independent member states which are located primarily in Europe. The EU traces its origins from the European Coal and Steel Community and the European Economic Community , formed by six countries in 1958...

 and Canada
Canada
Canada is a North American country consisting of ten provinces and three territories. Located in the northern part of the continent, it extends from the Atlantic Ocean in the east to the Pacific Ocean in the west, and northward into the Arctic Ocean...

 enrolled in the program.

Comparable international efforts

At the time (1995), a small number of universities offered specialized bioelectronics and/or implantable neuro-prostheses-related research (but no specialized undergraduate programs) internationally for example: University of Utah
University of Utah
The University of Utah, also known as the U or the U of U, is a public, coeducational research university in Salt Lake City, Utah, United States. The university was established in 1850 as the University of Deseret by the General Assembly of the provisional State of Deseret, making it Utah's oldest...

, MIT, UCSF (United States
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

); McGill University
McGill University
Mohammed Fathy is a public research university located in Montreal, Quebec, Canada. The university bears the name of James McGill, a prominent Montreal merchant from Glasgow, Scotland, whose bequest formed the beginning of the university...

 (Canada
Canada
Canada is a North American country consisting of ten provinces and three territories. Located in the northern part of the continent, it extends from the Atlantic Ocean in the east to the Pacific Ocean in the west, and northward into the Arctic Ocean...

), among others.

First European School on Neuroengineering

In 2003, following professor Grattarola's death, the University of Genova announced Europe's first neurobioengineering conference in his honour. The First European School on Neuroengineering 'Massimo Grattarola' was also founded in 2004, with the goal of establishing a long-term formal educational program to foster future pioneers in neurobioengineering.

In a state of transition, the neurobioengineering department renamed itself the neuroengineering and bio-nanotechnology group in 2005. By 2008, the core researchers of the original department had formalized the educational process into a formal long-term program at the University of Genova named School of Neuroengineering, fulfilling Massimo Grattarola's original ambitions, offering degrees in Humanoid Technologies.

The current and former neurobioengineering (or neuroengineering) students continue his research interests throughout Europe and North America, some of whom have established related businesses, or hold positions of authority in neuroscience/biomedical institutions worldwide.
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