Ludwig Pick
Encyclopedia
Professor Ludwig Pick was a German pathologist who was a native of Landsberg an der Warthe. In 1893 he earned his medical doctorate in Leipzig
, and subsequently practiced medicine at Leopold Landau
's private Frauenklinik, where he remained until 1906. That same year he became director of the department of pathological anatomy at the city hospital Friedrichshain
-Berlin
. Later, he was imprisoned by the Nazis, and died on February 3, 1944 at the Theresienstadt Concentration Camp.
Ludwig Pick made several contributions to academic pathology, particularly in the field of genitourinary diseases, and also in the study of melanotic
pigmentation. In 1912 he coined the term pheochromocytoma
to describe the chromaffin
color change in tumor
cells associated with adrenal medullary
tumors.
Leipzig
Leipzig Leipzig has always been a trade city, situated during the time of the Holy Roman Empire at the intersection of the Via Regia and Via Imperii, two important trade routes. At one time, Leipzig was one of the major European centres of learning and culture in fields such as music and publishing...
, and subsequently practiced medicine at Leopold Landau
Leopold Landau
Leopold Landau was a German gynecologist born in Warsaw.He studied medicine at the Universities of Breslau, Würzburg and Berlin, obtaining his doctorate at the latter institution in 1870. After serving as an assistant surgeon during the Franco-Prussian War, he was a lecturer in gynecology at the...
's private Frauenklinik, where he remained until 1906. That same year he became director of the department of pathological anatomy at the city hospital Friedrichshain
Friedrichshain
Friedrichshain is a part of Berlin's borough of Friedrichshain-Kreuzberg, and like Kreuzberg across the river it has its own distinct character, with the result that the new double name is hardly ever used outside government administration. From its creation in 1920 until Berlin's 2001...
-Berlin
Berlin
Berlin is the capital city of Germany and is one of the 16 states of Germany. With a population of 3.45 million people, Berlin is Germany's largest city. It is the second most populous city proper and the seventh most populous urban area in the European Union...
. Later, he was imprisoned by the Nazis, and died on February 3, 1944 at the Theresienstadt Concentration Camp.
Ludwig Pick made several contributions to academic pathology, particularly in the field of genitourinary diseases, and also in the study of melanotic
Melanoma
Melanoma is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye...
pigmentation. In 1912 he coined the term pheochromocytoma
Pheochromocytoma
A pheochromocytoma or phaeochromocytoma is a neuroendocrine tumor of the medulla of the adrenal glands , or extra-adrenal chromaffin tissue that failed to involute after birth and secretes excessive amounts of catecholamines, usually noradrenaline , and adrenaline to a lesser extent...
to describe the chromaffin
Chromaffin cell
Chromaffin cells are neuroendocrine cells found in the medulla of the adrenal gland and in other ganglia of the sympathetic nervous system. They are modified post-synaptic sympathetic neurons that receive sympathetic input...
color change in tumor
Tumor
A tumor or tumour is commonly used as a synonym for a neoplasm that appears enlarged in size. Tumor is not synonymous with cancer...
cells associated with adrenal medullary
Adrenal medulla
The adrenal medulla is part of the adrenal gland. It is located at the center of the gland, being surrounded by the adrenal cortex. It is the innermost part of the adrenal gland, consisting of cells that secrete epinephrine , norepinephrine , and a small amount of dopamine in response to...
tumors.
- Associated eponyms:
- Lubarsch-Pick syndrome: A rare combination of macroglossiaMacroglossiaMacroglossia is the medical term for unusual enlargement of the tongue. Severe enlargement of the tongue can cause cosmetic and functional difficulties including in speaking, eating, swallowing and sleeping.- Amyloid Disorders :...
with systematized amyloidosisAmyloidosisIn medicine, amyloidosis refers to a variety of conditions whereby the body produces "bad proteins", denoted as amyloid proteins, which are abnormally deposited in organs and/or tissues and cause harm. A protein is described as being amyloid if, due to an alteration in its secondary structure, it...
of the skin and skeletal muscleSkeletal muscleSkeletal muscle is a form of striated muscle tissue existing under control of the somatic nervous system- i.e. it is voluntarily controlled. It is one of three major muscle types, the others being cardiac and smooth muscle...
s. Named with pathologist Otto LubarschOtto LubarschOtto Lubarsch was a German pathologist who was a native of Berlin.He originally studied philosophy and natural sciences in Leipzig and Heidelberg, and later earned his medical degree in Strasbourg in 1883...
(1860-1933). - Niemann-Pick diseaseNiemann-Pick diseaseNiemann–Pick disease refers to a group of fatal inherited metabolic disorders that are included in the larger family of lysosomal storage diseases .-Signs and symptoms:Symptoms are related to the organs in which they accumulate...
: A biochemical disorder affecting a lipidLipidLipids constitute a broad group of naturally occurring molecules that include fats, waxes, sterols, fat-soluble vitamins , monoglycerides, diglycerides, triglycerides, phospholipids, and others...
fat called sphingomyelinSphingomyelinSphingomyelin is a type of sphingolipid found in animal cell membranes, especially in the membranous myelin sheath that surrounds some nerve cell axons. It usually consists of phosphorylcholine and ceramide...
, which usually results in progressive enlargement of the liverLiverThe liver is a vital organ present in vertebrates and some other animals. It has a wide range of functions, including detoxification, protein synthesis, and production of biochemicals necessary for digestion...
and spleenSpleenThe spleen is an organ found in virtually all vertebrate animals with important roles in regard to red blood cells and the immune system. In humans, it is located in the left upper quadrant of the abdomen. It removes old red blood cells and holds a reserve of blood in case of hemorrhagic shock...
(hepatosplenomegalyHepatosplenomegalyHepatosplenomegaly is the simultaneous enlargement of both the liver and the spleen . Hepatosplenomegaly can occur as the result of acute viral hepatitis or infectious mononucleosis, or it can be the sign of a serious and life threatening lysosomal storage disease...
), along with lymphadenopathyLymphadenopathyLymphadenopathy is a term meaning "disease of the lymph nodes." It is, however, almost synonymously used with "swollen/enlarged lymph nodes". It could be due to infection, auto-immune disease, or malignancy....
, anemiaAnemiaAnemia is a decrease in number of red blood cells or less than the normal quantity of hemoglobin in the blood. However, it can include decreased oxygen-binding ability of each hemoglobin molecule due to deformity or lack in numerical development as in some other types of hemoglobin...
and mental and physical deterioration. Named with Dr. Albert Niemann (paediatrician)Albert Niemann (paediatrician)Albert Niemann was a German physician.Niemann-Pick disease is named for him and Ludwig Pick.He was the son of Albert Niemann, a well known tenor with the same name.-References:...
(1880-1921).