Kanehiro Takaki
Encyclopedia
Baron was a Japan
Japan
Japan is an island nation in East Asia. Located in the Pacific Ocean, it lies to the east of the Sea of Japan, China, North Korea, South Korea and Russia, stretching from the Sea of Okhotsk in the north to the East China Sea and Taiwan in the south...

ese naval physician
Physician
A physician is a health care provider who practices the profession of medicine, which is concerned with promoting, maintaining or restoring human health through the study, diagnosis, and treatment of disease, injury and other physical and mental impairments...

.

Early life

Born in Hyūga Province
Hyuga Province
was an old province of Japan on the east coast of Kyūshū, corresponding to the modern Miyazaki Prefecture. It was sometimes called or . Hyūga bordered on Bungo, Higo, Ōsumi, and Satsuma Province.The ancient capital was near Saito.-Historical record:...

 (present-day Miyazaki Prefecture
Miyazaki Prefecture
is a prefecture of Japan located on the island of Kyushu. The capital is the city of Miyazaki.- History :Historically, after the Meiji Restoration, Hyūga Province was renamed Miyazaki Prefecture....

) as the son of a samurai
Samurai
is the term for the military nobility of pre-industrial Japan. According to translator William Scott Wilson: "In Chinese, the character 侍 was originally a verb meaning to wait upon or accompany a person in the upper ranks of society, and this is also true of the original term in Japanese, saburau...

retainer to the Satsuma
Satsuma han
The Satsuma domain was one of the most powerful feudal domains in Tokugawa Japan, and played a major role in the Meiji Restoration and in the government of the Meiji period which followed...

 domain, Takaki studied Chinese medicine as a youth and served as a medic in the Boshin War
Boshin War
The was a civil war in Japan, fought from 1868 to 1869 between forces of the ruling Tokugawa shogunate and those seeking to return political power to the imperial court....

. He later studied western medical science under British doctor William Willis (in Japan 1861–1881). Takaki entered the Imperial Japanese Navy
Imperial Japanese Navy
The Imperial Japanese Navy was the navy of the Empire of Japan from 1869 until 1947, when it was dissolved following Japan's constitutional renunciation of the use of force as a means of settling international disputes...

 as a medical officer in 1872. He was sent to Great Britain
Great Britain
Great Britain or Britain is an island situated to the northwest of Continental Europe. It is the ninth largest island in the world, and the largest European island, as well as the largest of the British Isles...

 for medical studies in 1875, and interned at St Thomas's Hospital Medical School in London
London
London is the capital city of :England and the :United Kingdom, the largest metropolitan area in the United Kingdom, and the largest urban zone in the European Union by most measures. Located on the River Thames, London has been a major settlement for two millennia, its history going back to its...

. He returned to Japan in 1880.

Work on beriberi

At the time, beriberi
Beriberi
Beriberi is a nervous system ailment caused by a thiamine deficiency in the diet. Thiamine is involved in the breakdown of energy molecules such as glucose and is also found on the membranes of neurons...

 (considered endemic to Japan) was a serious problem on warships and was affecting naval efficiency. Takaki knew that beriberi was not common among Western
Western world
The Western world, also known as the West and the Occident , is a term referring to the countries of Western Europe , the countries of the Americas, as well all countries of Northern and Central Europe, Australia and New Zealand...

 navies. He also noticed that Japanese naval officers, whose diet consisted of various types of vegetables and meat, rarely suffered from beriberi. On the other hand, the disease was common among ordinary crewmen, whose diet consisted almost exclusively of white rice
Rice
Rice is the seed of the monocot plants Oryza sativa or Oryza glaberrima . As a cereal grain, it is the most important staple food for a large part of the world's human population, especially in East Asia, Southeast Asia, South Asia, the Middle East, and the West Indies...

 (which was supplied free, whereas other foods had to be purchased). Many crewmen from poor families, who had to send money back home, often tried to save money by eating nothing but rice.

In 1883 Takaki learned of a very high incidence of beriberi among cadets on a training mission from Japan to Hawaii, via New Zealand and South America that lasted for 9 months. On board, 169 men out of 376 developed the disease and 25 died. Takaki made a petition to Emperor Meiji
Emperor Meiji
The or was the 122nd emperor of Japan according to the traditional order of succession, reigning from 3 February 1867 until his death...

 to fund an experiment with an improved diet for the seamen that included more meat, milk, bread and vegetables. He succeeded, and in 1884, another mission took the same route, but this time only sixteen beriberi cases among 333 seamen were reported. This experiment convinced the Imperial Japanese Navy that poor diet was the prime factor in beriberi, and the disease was soon eliminated from the fleet. Takaki's success occurred ten years before Christiaan Eijkman
Christiaan Eijkman
Christiaan Eijkman was a Dutch physician and professor of physiology whose demonstration that beriberi is caused by poor diet led to the discovery of vitamins...

, working in Batavia
Jakarta
Jakarta is the capital and largest city of Indonesia. Officially known as the Special Capital Territory of Jakarta, it is located on the northwest coast of Java, has an area of , and a population of 9,580,000. Jakarta is the country's economic, cultural and political centre...

, advanced his theory that beriberi was caused by a nutritional deficiency, with his later identification of vitamin B1 earning him the 1929 Nobel Prize in Physiology or Medicine
Nobel Prize in Physiology or Medicine
The Nobel Prize in Physiology or Medicine administered by the Nobel Foundation, is awarded once a year for outstanding discoveries in the field of life science and medicine. It is one of five Nobel Prizes established in 1895 by Swedish chemist Alfred Nobel, the inventor of dynamite, in his will...

).

Although Takaki clearly established that the cause was due to nutrition
Nutrition
Nutrition is the provision, to cells and organisms, of the materials necessary to support life. Many common health problems can be prevented or alleviated with a healthy diet....

al issues, this conflicted with the prevailing idea among medical scientists that beriberi was an infectious disease
Infectious disease
Infectious diseases, also known as communicable diseases, contagious diseases or transmissible diseases comprise clinically evident illness resulting from the infection, presence and growth of pathogenic biological agents in an individual host organism...

. The Imperial Japanese Army
Imperial Japanese Army
-Foundation:During the Meiji Restoration, the military forces loyal to the Emperor were samurai drawn primarily from the loyalist feudal domains of Satsuma and Chōshū...

, which was dominated by doctors from Tokyo Imperial University, persisted in their belief that beriberi was an infectious disease, for decades refused to implement a remedy. In the Russo-Japanese War
Russo-Japanese War
The Russo-Japanese War was "the first great war of the 20th century." It grew out of rival imperial ambitions of the Russian Empire and Japanese Empire over Manchuria and Korea...

 of 1904–1905 211,600 soldiers suffered from beriberi — 27,000 fatally, compared to 47,000 deaths from combat
Combat
Combat, or fighting, is a purposeful violent conflict meant to establish dominance over the opposition, or to terminate the opposition forever, or drive the opposition away from a location where it is not wanted or needed....

.

In 1905, Takaki was ennobled with the title of danshaku (baron
Baron
Baron is a title of nobility. The word baron comes from Old French baron, itself from Old High German and Latin baro meaning " man, warrior"; it merged with cognate Old English beorn meaning "nobleman"...

) under the kazoku
Kazoku
The was the hereditary peerage of the Empire of Japan that existed between 1869 and 1947.-Origins:Following the Meiji Restoration of 1868, the ancient court nobility of Kyoto regained some of its lost status...

peerage system for his contribution of eliminating beriberi from the Imperial Japanese Navy, and also awarded the Order of the Rising Sun
Order of the Rising Sun
The is a Japanese order, established in 1875 by Emperor Meiji of Japan. The Order was the first national decoration awarded by the Japanese Government, created on April 10, 1875 by decree of the Council of State. The badge features rays of sunlight from the rising sun...

 (first class). He was later affectionately nicknamed "Barley Baron".

Takaki founded the Sei-I-Kwai medical society in January 1881. In May, 1881, he founded the Sei-I-Kwai Koshujo (Sei-I-Kwai Medical Training School), now the Jikei University School of Medicine. Takaki's school was the first private medical college in Japan, and was the first in Japan to have students dissect human cadavers
Autopsy
An autopsy—also known as a post-mortem examination, necropsy , autopsia cadaverum, or obduction—is a highly specialized surgical procedure that consists of a thorough examination of a corpse to determine the cause and manner of death and to evaluate any disease or injury that may be present...

.

Takaki was posthumously honored by having a peninsula in Antarctica at 65°33′S 64°34′W named "Takaki Promontory" in his honor. It is the only peninsula in Antarctica named after a Japanese person.

External links

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