Ion channel family
Encyclopedia
Transmembrane ion channel family was defined in InterPro
and Pfam
as the family of tetrameric sodium, potassium, and calcium
ion channels, in which two C-terminal transmembrane helices flank a loop which determines ion selectivity of the channel pore. This large group of ion channels apparently includes families , , , and of transporter classification.
Many eukaryotic channels have four additional transmembrane helices (TMH) , whereas a bacterial structure of the protein has only two transmembrane helices that form the tetrameric channel .
Calcium
Potassium
Sodium
Proton
Cyclic nucleotide-gated
InterPro
InterPro is a database of protein families, domains and functional sites in which identifiable features found in known proteins can be applied to new protein sequences in order to functionally characterise them....
and Pfam
Pfam
Pfam is a database of protein families that includes their annotations and multiple sequence alignments generated using hidden Markov models.- Features :For each family in Pfam one can:* Look at multiple alignments* View protein domain architectures...
as the family of tetrameric sodium, potassium, and calcium
Voltage-dependent calcium channel
Voltage-dependent calcium channels are a group of voltage-gated ion channels found in excitable cells with a permeability to the ion Ca2+...
ion channels, in which two C-terminal transmembrane helices flank a loop which determines ion selectivity of the channel pore. This large group of ion channels apparently includes families , , , and of transporter classification.
Many eukaryotic channels have four additional transmembrane helices (TMH) , whereas a bacterial structure of the protein has only two transmembrane helices that form the tetrameric channel .
Human channels with 6 TM helices
Cation- MCOLN1; MCOLN2MCOLN2Mucolipin-2 also known as TRPML2 is a protein that in humans is encoded by the MCOLN2 gene...
; MCOLN3MCOLN3Mucolipin-3 also known as TRPML3 is a protein that in humans is encoded by the MCOLN3 gene. It is a member of the small family of the TRPML channels, a subgroup of the large protein family of TRP ion channels.-Gene:In human, the MCOLN3 gene resides on the short arm of chromosome 1 at 1p22.3...
; - PKD1L3;
- TRPA1TRPA1Transient receptor potential cation channel, subfamily A, member 1, also known as TRPA1, is a protein which in humans is encoded by the TRPA1 gene....
- TPCN1TPCN1Two pore segment channel 1 is a human protein encoded by the TPCN1 is a human gene. The protein encoded by this gene is an ion channel. In contrast to other calcium and sodium channels which have four homologous domains, each containing 6 transmembrane segments , TPCN1 only contains two domain ....
; TPCN2TPCN2Two pore segment channel 2 is a human protein encoded by the TPCN2 is a protein which in humans is encoded by the TPCN2 gene. TPC2 is an ion channel, however, in contrast to other calcium and sodium channels which have four homologous domains, each containing 6 transmembrane segments , TPCN1 only... - TRPC1TRPC1Transient receptor potential channel 1 is a protein that in humans is encoded by the TRPC1 gene.- Function :TRPC1 is an ion channel located on the plasma membrane of numerous human and animal cell types. It is a nonspecific cation channel, which means that both sodium and calcium ions can pass...
: TRPC3TRPC3Transient receptor potential cation channel, subfamily C, member 3, also known as TRPC3, is a human gene encoding a protein of the same name.-Interactions:TRPC3 has been shown to interact with TRPC1 and TRPC6.-Further reading:...
; TRPC4TRPC4Transient receptor potential cation channel, subfamily C, member 4, also known as TRPC4, is a human gene encoding a protein of the same name.-Interactions:TRPC4 has been shown to interact with TRPC1, ITPR1 and TRPC5.-Roles:...
; TRPC5TRPC5Short transient receptor potential channel 5 also known as transient receptor protein 5 is a protein that in humans is encoded by the TRPC5 gene. TrpC5 is subtype of the TRPC family of mammalian transient receptor potential ion channels.- Function :TrpC5 is one of the seven mammalian TRPC proteins...
; TRPC6TRPC6Transient receptor potential cation channel, subfamily C, member 6, also known as TRPC6, is a human gene encoding a protein of the same name. TRPC6 is a transient receptor potential ion channel...
; TRPC7TRPC7Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a human gene encoding a protein of the same name.... - TRPM1TRPM1Transient receptor potential cation channel subfamily M member 1 is a protein that in humans is encoded by the TRPM1 gene.- Function :The protein encoded by this gene is similar to the transient receptor potential calcium channel family members...
; TRPM2TRPM2Transient receptor potential cation channel, subfamily M, member 2, also known as TRPM2, is a protein that in humans is encoded by the TRPM2 gene.-Function:...
; TRPM3TRPM3Transient receptor potential cation channel subfamily M member 3 is a protein that in humans is encoded by the TRPM3 gene.TRPM3 was shown to be activated by the neurosteroid pregnenolone sulphate in pancreatic beta cell. The activation causes calcium influx and subsequent insulin release, therefore...
; TRPM4TRPM4Transient receptor potential cation channel subfamily M member 4 , also known as melastatin-4, is a protein that in humans is encoded by the TRPM4 gene....
; TRPM5TRPM5Transient receptor potential cation channel subfamily M member 5 , also known as long transient receptor potential channel 5 is a protein that in humans is encoded by the TRPM5 gene....
; TRPM6TRPM6TRPM6 is a transient receptor potential ion channel associated with hypomagnesemia with secondary hypocalcemia....
; TRPM7TRPM7Transient receptor potential cation channel, subfamily M, member 7, also known as TRPM7, is a human gene encoding a protein of the same name.- Function :...
; TRPM8TRPM8Transient receptor potential cation channel subfamily M member 8 , also known as the cold and menthol receptor 1 , is a protein that in humans is encoded by the TRPM8 gene.-Function:... - TRPV1TRPV1The transient receptor potential cation channel subfamily V member 1 ', also known as the capsaicin receptor and the vanilloid receptor 1, is a protein that, in humans, is encoded by the TRPV1 gene...
; TRPV2TRPV2Transient receptor potential cation channel subfamily V member 2 is a protein that in humans is encoded by the TRPV2 gene.- Function :This gene encodes an ion channel that is activated by high temperatures above 52 °C. The protein may be involved in transduction of high-temperature heat responses...
; TRPV3TRPV3Transient receptor potential cation channel, subfamily V, member 3, also known as TRPV3, is a human gene encoding the protein of the same name.- Physiology of TRPV3 channel :...
; TRPV4TRPV4Transient receptor potential cation channel subfamily V member 4 is a protein that in humans is encoded by the TRPV4 gene.This gene encodes TRPV4, a member of the OSM9-like transient receptor potential channel subfamily in the transient receptor potential superfamily of ion channels...
; TRPV5TRPV5Transient receptor potential cation channel subfamily V member 5 is a protein that in humans is encoded by the TRPV5 gene.TRPV5 is mainly expressed in kidney epithelial cells, where it plays an important role in the reabsorption of Ca2+.. Genetic deletion of TRPV5 in mice leads to Ca2+ loss in the...
; TRPV6TRPV6TRPV6 is a membrane calcium channel which is responsible for the first step in calcium absorption in the intestine. It was first named CAT1, or ECaC2, and has been described in the intestine in several species, including humans. It is located in the apical brush-border membrane of the intestinal...
Calcium
- CACNA1A; CACNA1B; CACNA1CCACNA1CCalcium channel, voltage-dependent, L type, alpha 1C subunit is a protein that in humans is encoded by the CACNA1C gene. Cav1.2 is a subunit of L-type voltage-dependent calcium channel.- Structure and function :...
; CACNA1D; CACNA1ER-type calcium channelThe R-type calcium channel is a type of voltage-dependent calcium channel. Like the others of this class, the α1 subunit forms the pore through which calcium enters the cell and determines most of the channel's properties...
; CACNA1F; CACNA1GCACNA1GCalcium channel, voltage-dependent, T type, alpha 1G subunit, also known as CACNA1G or Cav3.1 is a protein which in humans is encoded by the CACNA1G gene.- Function :...
; CACNA1HCACNA1HCalcium channel, voltage-dependent, T type, alpha 1H subunit, also known as CACNA1H, is a protein which in humans is encoded by the CACNA1H gene.- Function :...
; CACNA1ICACNA1ICalcium channel, voltage-dependent, T type, alpha 1I subunit, also known as CACNA1I or Cav3.3 is a protein which in humans is encoded by the CACNA1I gene.- Function :...
; CACNA1S - CATSPER1CatSper1CatSper1, is a protein which in humans is encoded by the CATSPER1 gene. CatSper1 is a member of the cation channels of sperm family of protein. The four proteins in this family together form a Ca2+-permeant ion channel specific essential for the correct function of sperm cells.- Function :Calcium...
; CATSPER2CatSper2CatSper2, is a protein which in humans is encoded by the CATSPER2 gene. CatSper2 is a member of the cation channels of sperm family of protein. The four proteins in this family together form a Ca2+-permeant ion channel specific essential for the correct function of sperm cells.- Function :Calcium...
; CATSPER3CatSper3CatSper3, is a protein which in humans is encoded by the CATSPER3 gene. CatSper3 is a member of the cation channels of sperm family of proteins. The four proteins in this family together form a Ca2+-permeant ion channel specific essential for the correct function of sperm cells....
; CATSPER4CatSper4CatSper4, is a protein which in humans is encoded by the CATSPER4 gene. CatSper1 is a member of the cation channels of sperm family of protein. The four proteins in this family together form a Ca2+-permeant ion channel specific essential for the correct function of sperm cells.... - RYR1RYR1Ryanodine receptor 1 also known as skeletal muscle calcium release channel or skeletal muscle-type ryanodine receptor is a protein primarily found in skeletal muscle...
; RYR2; RYR3RYR3Ryanodine receptor 3 is a protein that in humans is encoded by the RYR3 gene. The protein encoded by this gene is both a calcium channel and a receptor for the plant alkaloid ryanodine. RYR3 along with RYR1 control the resting calcium ion concentration in skeletal muscle....
Potassium
- KCNA1KCNA1Potassium voltage-gated channel subfamily A member 1 also known as Kv1.1 is a shaker related voltage-gated potassium channel that in humans is encoded by the KCNA1 gene. The Isaacs syndrome is a result of an autoimmune reaction against the Kv1.1 ion channel.- Genomics :The gene is located on the...
; KCNA2KCNA2Potassium voltage-gated channel subfamily A member 2 also known as Kv1.2 is a protein that in humans is encoded by the KCNA2 gene.-Interactions:KCNA2 has been shown to interact with KCNA4, DLG4, PTPRA, KCNAB2, RHOA and Cortactin....
; KCNA3KCNA3Potassium voltage-gated channel, shaker-related subfamily, member 3, also known as KCNA3 or Kv1.3, is a protein which in humans is encoded by the KCNA3 gene....
; KCNA4KCNA4Potassium voltage-gated channel subfamily A member 4 also known as Kv1.4 is a protein that in humans is encoded by the KCNA4 gene. It contributes to the cardiac transient outward potassium current , the main contributing current to the repolarizing phase 1 of the cardiac action...
; KCNA5KCNA5Potassium voltage-gated channel, shaker-related subfamily, member 5, also known as KCNA5 or Kv1.5, is a protein that in humans is encoded by the KCNA5 gene.-Function:...
; KCNA6KCNA6Potassium voltage-gated channel subfamily A member 6 also known as Kv1.6 is a protein that in humans is encoded by the KCNA6 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit....
; KCNA7KCNA7Potassium voltage-gated channel subfamily A member 7 also known as Kv1.7 is a protein that in humans is encoded by the KCNA7 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit. It may contribute to the cardiac transient outward potassium current , the main...
; KCNA10KCNA10Potassium voltage-gated channel subfamily A member 10 also known as Kv1.8 is a protein that in humans is encoded by the KCNA10 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.... - KCNB1KCNB1Potassium voltage-gated channel, Shab-related subfamily, member 1, also known as KCNB1 or Kv2.1, is a protein which in humans is encoded by the KCNB1 gene.-Species and tissue distribution:...
; KCNB2KCNB2Potassium voltage-gated channel subfamily B member 2 is a protein that in humans is encoded by the KCNB2 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.... - KCNC1KCNC1Potassium voltage-gated channel subfamily C member 1 is a protein that in humans is encoded by the KCNC1 gene.The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and comprises four subfamilies. Based on sequence similarity, this gene is similar to one of...
; KCNC2KCNC2Potassium voltage-gated channel subfamily C member 2 is a protein that in humans is encoded by the KCNC2 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.-Expression pattern:...
; KCNC3KCNC3Potassium voltage-gated channel, Shaw-related subfamily, member 3 also known as KCNC3 or Kv3.3 is a protein which in humans is encoded by the KCNC3.- Function :...
; KCNC4KCNC4Potassium voltage-gated channel, Shaw-related subfamily, member 4 , also known as Kv3.4, is a human gene.-Further reading:... - KCND1KCND1Potassium voltage-gated channel, Shal-related subfamily, member 1 , also known as Kv4.1, is a human gene.-Further reading:...
; KCND2KCND2Potassium voltage-gated channel subfamily D member 2 is a protein that in humans is encoded by the KCND2 gene. It contributes to the cardiac transient outward potassium current , the main contributing current to the repolarizing phase 1 of the cardiac action...
; KCND3KCND3Potassium voltage-gated channel subfamily D member 3 also known as Kv4.3 is a protein that in humans is encoded by the KCND3 gene. It contributes to the cardiac transient outward potassium current , the main contributing current to the repolarizing phase 1 of the cardiac action potential.- Function... - KCNF1KCNF1Potassium voltage-gated channel subfamily F member 1 is a protein that in humans is encoded by the KCNF1 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit....
- KCNG1KCNG1Potassium voltage-gated channel subfamily G member 1 is a protein that in humans is encoded by the KCNG1 gene....
; KCNG2KCNG2Potassium voltage-gated channel subfamily G member 2 is a protein that in humans is encoded by the KCNG2 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit....
; KCNG3KCNG3Potassium voltage-gated channel subfamily G member 3 is a protein that in humans is encoded by the KCNG3 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit....
; KCNG4KCNG4Potassium voltage-gated channel subfamily G member 4 is a protein that in humans is encoded by the KCNG4 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.... - KCNH1KCNH1Potassium voltage-gated channel subfamily H member 1 is a protein that in humans is encoded by the KCNH1 gene.- External links :...
; KCNH2; KCNH3KCNH3Potassium voltage-gated channel subfamily H member 3 is a protein that in humans is encoded by the KCNH3 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit....
; KCNH4KCNH4Potassium voltage-gated channel subfamily H member 4 is a protein that in humans is encoded by the KCNH4 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit....
; KCNH5KCNH5Potassium voltage-gated channel, subfamily H , member 5, also known as KCNH5, is a human gene encoding the Kv10.2 protein. -Further reading:...
; KCNH6KCNH6Potassium voltage-gated channel subfamily H member 6 is a protein that in humans is encoded by the KCNH6 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit....
; KCNH7KCNH7Potassium voltage-gated channel subfamily H member 7 is a protein that in humans is encoded by the KCNH7 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit....
; KCNH8KCNH8Potassium voltage-gated channel subfamily H member 8 is a protein that in humans is encoded by the KCNH8 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit.... - KCNMA1KCNMA1Calcium-activated potassium channel subunit alpha-1 also known as potassium large conductance calcium-activated channel, subfamily M, alpha member 1 is a voltage gated ion channel encoded by the KCNMA1 gene.- Function :...
- KCNQ1; KCNQ2; KCNQ3; KCNQ4KCNQ4Potassium voltage-gated channel subfamily KQT member 4 is a protein that in humans is encoded by the KCNQ4 gene.- External links :*...
; KCNQ5KCNQ5Potassium voltage-gated channel subfamily KQT member 5 is a protein that in humans is encoded by the KCNQ5 gene.-Further reading:... - KCNS1KCNS1Potassium voltage-gated channel subfamily S member 1 is a protein that in humans is encoded by the KCNS1 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit....
; KCNS2KCNS2Potassium voltage-gated channel subfamily S member 2 is a protein that in humans is encoded by the KCNS2 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit....
; KCNS3KCNS3Potassium voltage-gated channel subfamily S member 3 is a protein that in humans is encoded by the KCNS3 gene.-Further reading:... - KCNV1KCNV1Potassium voltage-gated channel subfamily V member 1 is a protein that in humans is encoded by the KCNV1 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit....
; KCNV2KCNV2Potassium voltage-gated channel subfamily V member 2 is a protein that in humans is encoded by the KCNV2 gene. The protein encoded by this gene is a voltage-gated potassium channel subunit....
Sodium
- NALCN
- SCN1A; SCN2A; SCN2A2; SCN3ASCN3ASodium channel, voltage-gated, type III, alpha subunit is a protein that in humans is encoded by the Nav1.3 gene.- External links :...
; SCN4ASCN4ASodium channel protein type 4 subunit alpha is a protein that in humans is encoded by the SCN4A gene.The Nav1.4 voltage-gated sodium channel is encoded by the gene...
; SCN5ASCN5AThe Nav1.5 is a sodium ion channel protein that in humans is encoded by the SCN5A gene. Mutations in the gene are associated with long QT syndrome type 3 , Brugada syndrome, primary cardiac conduction disease and idiopathic ventricular fibrillation....
; SCN7ASCN7ASodium channel protein type 7 subunit alpha is a protein that in humans is encoded by the SCN7A gene.-See also:* Sodium channelScn7a is the name of the gene that encodes to a membrane protein, in particular a Sodium Channel Nax It belongs to a family of Sodium Channel known as Voltage-Gated, but...
; SCN8ASCN8ASodium channel, voltage gated, type VIII, alpha subunit also known as SCN8A or Nav1.6 is a protein which in humans is encoded by the SCN8A gene...
; SCN9A; SCN10ASCN10ASodium channel, voltage gated, type X, alpha subunit also known as SCN10A or Nav1.8 is a protein which in humans is encoded by the SCN10A gene.Nav1.8 is a sodium channel subunit.-Function:...
; SCN11A - SLC9A10SLC9A10Sodium/hydrogen exchanger 10, also known as solute carrier family 9 member 10, is a protein that in humans is encoded by the SLC9A10 gene.- Function :...
; SLC9A11SLC9A11Sodium/hydrogen exchanger 11, also known as solute carrier family 9, member 11, is a protein that in humans is encoded by the SLC9A11 gene. SLC9A11 is a member of the sodium-hydrogen exchanger family....
Proton
- HVCN1HVCN1The HVCN1 gene codes for a voltage-gated proton channel that has been shown to allow proton transport into phagosomes and out of many types of cells including spermatozoa, electrically excitable cells and respiratory epithelial cells...
Cyclic nucleotide-gated
- CNGA1; CNGA2; CNGA3; CNGA4
- CNGB1CNGB1Cyclic nucleotide gated channel beta 1, also known as CNGB1, is a human gene encoding an ion channel protein.-External links:*...
; CNGB3 - HCN1HCN1Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 is a protein that in humans is encoded by the HCN1 gene.- External links :...
; HCN2HCN2Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated ion channel 2 is a protein that in humans is encoded by the HCN2 gene.-Interactions:HCN2 has been shown to interact with HCN1 and HCN4.-Function:...
; HCN3HCN3Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 is a protein that in humans is encoded by the HCN3 gene....
; HCN4HCN4Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 is a protein that in humans is encoded by the HCN4 gene.There are four HCN channels. HCN4 is prominently expressed in the pace maker region of the mammalian heart. Some humans with bradycardia and Sick sinus syndrome... - ITPR1ITPR1Inositol 1,4,5-trisphosphate receptor type 1 is a protein that in humans is encoded by the ITPR1 gene.-Interactions:ITPR1 has been shown to interact with CA8, PRKG1, FKBP1A, MRVI1, RHOA, AHCYL1, EPB41L1 and TRPC4.-External Links:*...
; ITPR2ITPR2Inositol 1,4,5-trisphosphate receptor, type 2, also known as ITPR2, is a protein which in humans is encoded by the ITPR2 gene. The protein encoded by this gene is a both a receptor for inositol triphosphate and a calcium channel....
; ITPR3ITPR3Inositol 1,4,5-trisphosphate receptor, type 3, also known as ITPR3, is a protein which in humans is encoded by the ITPR3 gene. The protein encoded by this gene is a both a receptor for inositol triphosphate and a calcium channel....
Human channels with two TM helices in each subunit, as in bacteria
Potassium- KCNK1KCNK1Potassium channel subfamily K member 1 is a protein that in humans is encoded by the KCNK1 gene....
; KCNK2KCNK2Potassium channel subfamily K member 2 is a protein that in humans is encoded by the KCNK2 gene.- External links :...
; KCNK3KCNK3Potassium channel subfamily K member 3 is a protein that in humans is encoded by the KCNK3 gene.-Interactions:KCNK3 has been shown to interact with YWHAB and S100A10.- External links :...
; KCNK4KCNK4Potassium channel subfamily K member 4 is a protein that in humans is encoded by the KCNK4 gene....
; KCNK5KCNK5Potassium channel subfamily K member 5 is a protein that in humans is encoded by the KCNK5 gene....
; KCNK6KCNK6Potassium channel subfamily K member 6 is a protein that in humans is encoded by the KCNK6 gene....
; KCNK7KCNK7Potassium channel, subfamily K, member 7, also known as KCNK7 or K2P7.1 is a protein which in humans is encoded by the KCNK7 gene. K2P7.1 is a potassium channel containing two pore-forming P domains...
; KCNK9KCNK9Potassium channel subfamily K member 9 is a protein that in humans is encoded by the KCNK9 gene.This gene encodes K2P9.1, one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. This open channel is highly expressed in the cerebellum...
; KCNK10KCNK10Potassium channel, subfamily K, member 10, also known as KCNK10 is a human gene. The protein encoded by this gene, K2P10.1, is a potassium channel containing two pore-forming P domains....
; KCNK12KCNK12Potassium channel, subfamily K, member 12, also known as KCNK12 is a human gene. The protein encoded by this gene, K2P12.1, is a potassium channel containing two pore-forming P domains....
; KCNK13KCNK13Potassium channel, subfamily K, member 13, also known as KCNK13 is a human gene. The protein encoded by this gene, K2P13.1 is a potassium channel containing two pore-forming P domains....
; KCNK15KCNK15Potassium channel subfamily K member 15 is a protein that in humans is encoded by the KCNK15 gene....
; KCNK16KCNK16Potassium channel subfamily K member 16 is a protein that in humans is encoded by the KCNK16 gene. The protein encoded by this gene, K2P16.1, is a potassium channel containing two pore-forming P domains....
; KCNK17KCNK17Potassium channel subfamily K member 17 is a protein that in humans is encoded by the KCNK17 gene....
; KCNK18KCNK18Potassium channel subfamily K member 18 , also known as TWIK-related spinal cord potassium channel or K2P18.1 is a protein that in humans is encoded by the KCNK18 gene. K2P18.1 is a potassium channel containing two pore-forming P domains.A flaw in this gene could help trigger migraine headaches... - KCNN1KCNN1Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1 , also known as KCNN1 is a human gene encoding the KCa2.1 protein.-Further reading:...
; KCNN2KCNN2Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2, also known as KCNN2, is a protein which in humans is encoded by the KCNN2 gene...
; KCNN3; KCNN4KCNN4Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4, also known as KCNN4, is a human gene encoding the KCa3.1 protein.- Function :...
; - KCNT1KCNT1Potassium channel subfamily T, member 1, also known as KCNT1 is a human gene that encodes the KCa4.1 protein. KCa4.1 is a member of the calcium-activated potassium channel protein family...
; KCNT2KCNT2Potassium channel subfamily T, member 2, also known as KCNT2 is a human gene that encodes the KCa4.2 protein. KCa4.2 is a member of the calcium-activated potassium channel protein family...