KCNK7
Encyclopedia
Potassium channel, subfamily K, member 7, also known as KCNK7 or K2P7.1 is a protein
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

 which in humans is encoded by the KCNK7 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

. K2P7.1 is a potassium channel
Potassium channel
In the field of cell biology, potassium channels are the most widely distributed type of ion channel and are found in virtually all living organisms. They form potassium-selective pores that span cell membranes...

 containing two pore-forming P domains. Multiple transcript variants encoding different isoforms have been found for this gene.

Function

This gene encodes a member of the superfamily of potassium channel
Potassium channel
In the field of cell biology, potassium channels are the most widely distributed type of ion channel and are found in virtually all living organisms. They form potassium-selective pores that span cell membranes...

 proteins containing two pore-forming P domains
Tandem pore domain potassium channel
The two-pore-domain potassium channel is a family of 15 members form what is known as "leak channels" which possess Goldman-Hodgkin-Katz rectification. These channels are regulated by several mechanisms including oxygen tension, pH, mechanical stretch, and G-proteins...

. The product of this gene has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity.
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