Inter-ictal spiking
Encyclopedia
Inter-ictal spiking refers to abnormal neuronal discharges between epileptic seizures. This abnormal activity can originate from one or more cranial lobes, often travels from one lobe to another,and interferes with normal activity from the affected lobe. Patients with severe, intractable forms of epilepsy
Epilepsy
Epilepsy is a common chronic neurological disorder characterized by seizures. These seizures are transient signs and/or symptoms of abnormal, excessive or hypersynchronous neuronal activity in the brain.About 50 million people worldwide have epilepsy, and nearly two out of every three new cases...

 can suffer from unremmiting abnormal brain
Brain
The brain is the center of the nervous system in all vertebrate and most invertebrate animals—only a few primitive invertebrates such as sponges, jellyfish, sea squirts and starfishes do not have one. It is located in the head, usually close to primary sensory apparatus such as vision, hearing,...

 activity due to inter-ictal spiking.

This phenomenon has been confirmed through intra-cranial EEG
EEG
EEG commonly refers to electroencephalography, a measurement of the electrical activity of the brain.EEG may also refer to:* Emperor Entertainment Group, a Hong Kong-based entertainment company...

 telemetry
Telemetry
Telemetry is a technology that allows measurements to be made at a distance, usually via radio wave transmission and reception of the information. The word is derived from Greek roots: tele = remote, and metron = measure...

 in which electrode
Electrode
An electrode is an electrical conductor used to make contact with a nonmetallic part of a circuit...

 grids are positioned sub-durally and augmented by intra-cranial depth electrodes. The EEG tracings from these are correlated with external video recordings of physical responses to epilepctic
Epilepsy
Epilepsy is a common chronic neurological disorder characterized by seizures. These seizures are transient signs and/or symptoms of abnormal, excessive or hypersynchronous neuronal activity in the brain.About 50 million people worldwide have epilepsy, and nearly two out of every three new cases...

seizures to help determine type of seizure and origin of onset.
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