Hazard (risk)
Encyclopedia
A hazard is any biological
Biological agent
A biological agent — also called bio-agent or biological threat agent — is a bacterium, virus, prion, or fungus which may cause infection, allergy, toxicity or otherwise create a hazard to human health. They can be used as a biological weapon in bioterrorism or biological warfare...

, chemical, mechanical, or physical agent that is reasonably likely to cause harm or damage to humans, other organisms, or the environment in the absence of its control.. This can include, but is not limited to: asbestos
Asbestos
Asbestos is a set of six naturally occurring silicate minerals used commercially for their desirable physical properties. They all have in common their eponymous, asbestiform habit: long, thin fibrous crystals...

, electricity
Electricity
Electricity is a general term encompassing a variety of phenomena resulting from the presence and flow of electric charge. These include many easily recognizable phenomena, such as lightning, static electricity, and the flow of electrical current in an electrical wire...

, microbial pathogens, motor vehicles
Motor vehicle
A motor vehicle or road vehicle is a self-propelled wheeled vehicle that does not operate on rails, such as trains or trolleys. The vehicle propulsion is provided by an engine or motor, usually by an internal combustion engine, or an electric motor, or some combination of the two, such as hybrid...

, nuclear power plants
Nuclear power plant
A nuclear power plant is a thermal power station in which the heat source is one or more nuclear reactors. As in a conventional thermal power station the heat is used to generate steam which drives a steam turbine connected to a generator which produces electricity.Nuclear power plants are usually...

, pesticides
Pesticide
Pesticides are substances or mixture of substances intended for preventing, destroying, repelling or mitigating any pest.A pesticide may be a chemical unicycle, biological agent , antimicrobial, disinfectant or device used against any pest...

, vaccines
Vaccine
A vaccine is a biological preparation that improves immunity to a particular disease. A vaccine typically contains an agent that resembles a disease-causing microorganism, and is often made from weakened or killed forms of the microbe or its toxins...

, and X-rays
X-ray
X-radiation is a form of electromagnetic radiation. X-rays have a wavelength in the range of 0.01 to 10 nanometers, corresponding to frequencies in the range 30 petahertz to 30 exahertz and energies in the range 120 eV to 120 keV. They are shorter in wavelength than UV rays and longer than gamma...

. Identification of hazards is the first step in performing a risk assessment
Risk assessment
Risk assessment is a step in a risk management procedure. Risk assessment is the determination of quantitative or qualitative value of risk related to a concrete situation and a recognized threat...

.

Biological

A biological hazard
Biological agent
A biological agent — also called bio-agent or biological threat agent — is a bacterium, virus, prion, or fungus which may cause infection, allergy, toxicity or otherwise create a hazard to human health. They can be used as a biological weapon in bioterrorism or biological warfare...

 is one originating from an organism that is foreign (in presence or concentration) to the organism being affected. Many biological hazards are associated with food, including certain viruses, parasites, fungi, bacteria, and plant and seafood toxins. Foodborne illnesses from Campylobacter
Campylobacter
Campylobacter is a genus of bacteria that are Gram-negative, spiral, and microaerophilic. Motile, with either unipolar or bipolar flagella, the organisms have a characteristic spiral/corkscrew appearance and are oxidase-positive. Campylobacter jejuni is now recognized as one of the main causes...

and Salmonella
Salmonella
Salmonella is a genus of rod-shaped, Gram-negative, non-spore-forming, predominantly motile enterobacteria with diameters around 0.7 to 1.5 µm, lengths from 2 to 5 µm, and flagella which grade in all directions . They are chemoorganotrophs, obtaining their energy from oxidation and reduction...

, are common foodborne biological hazards and are some of the most preventable hazards as they can be avoided through proper handling, storing, and cooking of food. Disease in humans can come from biological hazards in the form of infection by bacteria, viruses, or parasites. There is some concern that new technologies such as genetic engineering pose biological hazards. Genetically modified organisms are relatively new man-made biological hazards and many have yet to be fully characterized. For example, corn expressing insecticidal Cry proteins from the bacterium Bacillus thuringiensis
Bacillus thuringiensis
Bacillus thuringiensis is a Gram-positive, soil-dwelling bacterium, commonly used as a biological pesticide; alternatively, the Cry toxin may be extracted and used as a pesticide. B...

was first introduced in 1996 and many of its potential detrimental effects on non-target organisms have yet to be examined.

Chemical

A chemical can be considered an incident which by virtue of is intrinsic properties. it can cause harm or danger to humans, property, or the environment. Some chemicals occur naturally in certain geological formations, such as radon gas or arsenic
Arsenic
Arsenic is a chemical element with the symbol As, atomic number 33 and relative atomic mass 74.92. Arsenic occurs in many minerals, usually in conjunction with sulfur and metals, and also as a pure elemental crystal. It was first documented by Albertus Magnus in 1250.Arsenic is a metalloid...

. These chemicals become hazards when human activities, like constructing a home or digging a well, create the potential for exposure. Chemicals include products with commercial uses, such as agricultural and industrial chemicals, as well as products developed for home use. Pesticides, which are normally used to control unwanted insects and plants, may cause a variety of negative effects on non-target organisms. DDT
DDT
DDT is one of the most well-known synthetic insecticides. It is a chemical with a long, unique, and controversial history....

 can build up, or bioaccumulate, in birds resulting in thinner-than-normal egg shells which can break in the nest. The organochlorine pesticide dieldrin
Dieldrin
Dieldrin is a chlorinated hydrocarbon originally produced in 1948 by J. Hyman & Co, Denver, as an insecticide. Dieldrin is closely related to aldrin, which reacts further to form dieldrin. Aldrin is not toxic to insects; it is oxidized in the insect to form dieldrin which is the active compound...

 has been linked to Parkinson’s disease. Corrosive chemicals like sulfuric acid
Sulfuric acid
Sulfuric acid is a strong mineral acid with the molecular formula . Its historical name is oil of vitriol. Pure sulfuric acid is a highly corrosive, colorless, viscous liquid. The salts of sulfuric acid are called sulfates...

, which is found in car batteries and research laboratories can cause severe skin burns. Many other chemicals used in industrial and laboratory settings can cause respiratory, digestive, or nervous systems problems if they are inhaled, ingested, or absorbed through the skin. The negative effects of other chemicals, such as alcohol
Alcohol
In chemistry, an alcohol is an organic compound in which the hydroxy functional group is bound to a carbon atom. In particular, this carbon center should be saturated, having single bonds to three other atoms....

 and nicotine
Nicotine
Nicotine is an alkaloid found in the nightshade family of plants that constitutes approximately 0.6–3.0% of the dry weight of tobacco, with biosynthesis taking place in the roots and accumulation occurring in the leaves...

, have been well documented. Hazards associated with chemicals are dependent on the dose or amount of the chemical. For example, iodine in the form of potassium iodate is used to produce iodised salt
Iodised salt
Iodised salt is table salt mixed with a minute amount of various iodine-containing salts. The ingestion of iodide prevents iodine deficiency. Worldwide, iodine deficiency affects about two billion people and is the leading preventable cause of mental retardation. It also causes thyroid gland...

. When applied at a rate of 20 mg of potassium iodate per 1000 mg of table salt, the chemical is beneficial in preventing goiter, while iodine
Iodine
Iodine is a chemical element with the symbol I and atomic number 53. The name is pronounced , , or . The name is from the , meaning violet or purple, due to the color of elemental iodine vapor....

 intakes of 1200-9500 mg in one dose have been known to cause death

Mechanical

A mechanical hazard is any hazard involving a machine or process. Motor vehicles, aircraft, and air bags pose mechanical hazards. Compressed gases or liquids can also be considered a mechanical hazard.

Physical

A physical hazard is a naturally occurring process that has the potential to create loss or damage. Physical hazards include, but are not limited to, earthquakes, floods, and tornados. Physical hazards often have both human and natural elements. Floods problems can be affected by climate fluctuations and storm frequency, both natural elements, and by land drainage and building in a flood plain, human elements. Another physical hazard, X-rays, are naturally occurring from solar radiation, but have been utilized by humans for medical purposes; however, overexposure can lead to cancer
Cancer
Cancer , known medically as a malignant neoplasm, is a large group of different diseases, all involving unregulated cell growth. In cancer, cells divide and grow uncontrollably, forming malignant tumors, and invade nearby parts of the body. The cancer may also spread to more distant parts of the...

, skin burns, and tissue damage.

Hazard v. Risk

The terms hazard
Hazard
A hazard is a situation that poses a level of threat to life, health, property, or environment. Most hazards are dormant or potential, with only a theoretical risk of harm; however, once a hazard becomes "active", it can create an emergency situation. A hazard does not exist when it is not...

 and risk
Risk
Risk is the potential that a chosen action or activity will lead to a loss . The notion implies that a choice having an influence on the outcome exists . Potential losses themselves may also be called "risks"...

 are often used interchangeably. In terms of risk assessment, these are two very distinct terms. As defined above, a hazard is any biological, chemical, mechanical, or physical agent that is reasonably likely to cause harm or damage to humans or the environment in the absence of its control. Risk is defined as the probability that exposure to a hazard will lead to a negative consequence, or more simply, Risk = Hazard x Dose (Exposure). Thus, a hazard poses no risk if there is not exposure to that hazard. Consider the following example:


Three people crossing the Atlantic in a rowboat face a hazard of drowning. (…) Three hundred people crossing the Atlantic in an ocean liner face the same hazard of drowning, (…). The risk to each individual per crossing is given by the probability of the occurrence of an accident in which he or she drowns. (…) Clearly the hazard [drowning] is the same for each individual, but the risk [probability of drowning] is greater for the individuals in the rowboat than in the ocean liner.

Mechanical and Physical Hazards

Many mechanical hazards (aircraft, motor vehicles) and physical hazards (earthquakes, floods) have already been identified and well described. Hazard identification of new machines and/or industrial processes occurs at various stages in the design of the new machine or process. These hazard identification studies focus mainly on deviations from the intended use or design and the harm that may occur as a result of these deviations and are regulated by various agencies such as the Occupational Safety and Health Administration
Occupational Safety and Health Administration
The United States Occupational Safety and Health Administration is an agency of the United States Department of Labor. It was created by Congress of the United States under the Occupational Safety and Health Act, signed by President Richard M. Nixon, on December 29, 1970...

 and the National Highway Traffic Safety Administration
National Highway Traffic Safety Administration
The National Highway Traffic Safety Administration is an agency of the Executive Branch of the U.S. government, part of the Department of Transportation...

.

Biological Hazards

Many biological hazards have also been well characterized. For example, the hazards of naturally-occurring bacteria such as Escherichia coli
Escherichia coli
Escherichia coli is a Gram-negative, rod-shaped bacterium that is commonly found in the lower intestine of warm-blooded organisms . Most E. coli strains are harmless, but some serotypes can cause serious food poisoning in humans, and are occasionally responsible for product recalls...

and Salmonella
Salmonella
Salmonella is a genus of rod-shaped, Gram-negative, non-spore-forming, predominantly motile enterobacteria with diameters around 0.7 to 1.5 µm, lengths from 2 to 5 µm, and flagella which grade in all directions . They are chemoorganotrophs, obtaining their energy from oxidation and reduction...

, are well known as disease causing pathogens and a variety of measures have been taken to limit human exposure to these microorganisms through food safety, good personal hygiene and education. However, the potential for new biological hazards exist through the discovery of new microorganisms and through the development of new genetically modified (GM) organisms. Use of new GM organisms is regulated by various governmental agencies. The U.S. Environmental Protection Agency (EPA) controls GM plants that produce or resist pesticides (i.e. Bt corn and Roundup ready crops). The U.S. Food and Drug Administration
Food and Drug Administration
The Food and Drug Administration is an agency of the United States Department of Health and Human Services, one of the United States federal executive departments...

 (FDA) regulates GM plants that will be used as food or for medicinal purposes.

Chemical Hazards

A variety of chemical hazards (DDT, atrazine
Atrazine
Atrazine, 2-chloro-4--6--s-triazine, an organic compound consisting of an s-triazine-ring is a widely used herbicide. Its use is controversial due to widespread contamination in drinking water and its associations with birth defects and menstrual problems when consumed by humans at concentrations...

) have been described as well. However, every year companies produce more new chemicals to fill a new need or to take the place of an older, less effective chemical. Laws, such as the Federal Food, Drug, and Cosmetic Act
Federal Food, Drug, and Cosmetic Act
The United States Federal Food, Drug, and Cosmetic Act , is a set of laws passed by Congress in 1938 giving authority to the U.S. Food and Drug Administration to oversee the safety of food, drugs, and cosmetics. A principal author of this law was Royal S. Copeland, a three-term U.S. Senator from...

 and the Toxic Substances Control Act
Toxic Substances Control Act
The Toxic Substances Control Act is a United States law, passed by the United States Congress in 1976, that regulates the introduction of new or already existing chemicals. It grandfathered most existing chemicals, in contrast to the Registration, Evaluation and Authorization of Chemicals ...

in the U.S, require protection to human health and the environment for any new chemical introduced. In the U.S., the EPA regulates new chemicals that may have environmental impacts (i.e. pesticides or chemicals released during a manufacturing process), while the FDA regulates new chemicals used in foods or as drugs. The potential hazards of these chemicals can be identified by performing a variety of tests prior to the authorization of usage. The amount of tests required and the extent to which they are tested varies depending on the desired usage of the chemical. Chemicals designed as new drugs must undergo more rigorous tests that those chemicals to be used as pesticides.
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