HLA-B59
Encyclopedia
| Alleles | B*5901 | |
| Structure (See HLA-B HLA-B HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex... ) |
||
| Symbol(s) Human Genome Organisation The Human Genome Organisation is an organization involved in the Human Genome Project, a project about mapping the human genome. HUGO was established in 1989 as an international organization, primarily to foster collaboration between genome scientists around the world... |
HLA-B | |
| EBI-HLA European Bioinformatics Institute The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory... |
B*5901 | |
| Locus Locus (genetics) In the fields of genetics and genetic computation, a locus is the specific location of a gene or DNA sequence on a chromosome. A variant of the DNA sequence at a given locus is called an allele. The ordered list of loci known for a particular genome is called a genetic map... |
chr.6 Chromosome 6 (human) Chromosome 6 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 6 spans more than 170 million base pairs and represents between 5.5 and 6% of the total DNA in cells... 6p21.31 |
|
HLA-B59 (B59) is an HLA
Human leukocyte antigen
The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...
-B
HLA-B
HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex...
serotype
Serotype
Serotype or serovar refers to distinct variations within a subspecies of bacteria or viruses. These microorganisms, viruses, or cells are classified together based on their cell surface antigens...
. The serotype identifies the more common HLA-B*## gene products. B59 is a hybrid between B*55
HLA-B55
HLA-B55 is an HLA-B serotype. B55 is a split antigen from the B22 broad antigen, sister serotypes are B54 and B56. The serotype identifies the more common HLA-B*55 gene products. -Serotype:...
and B*51
HLA-B51
HLA-B51 is an HLA-B serotype. The serotype identifies the more common HLA-B*51 gene products.B51 is a split antigen of the broad antigen B5, and is a sister serotype of B52. There are a large number of alleles within the B*51 allele group...
. B59 is more common in Japan, Korea, N. China and Mongolia. (For terminology help see: HLA-serotype tutorial)
Serotype
| B*59 | B59 | Other | Sample |
| allele | % | % | size (N) |
| 5901 | 45 | 41 | 123 |
B*5901 allele frequencies
| freq | ||
| ref. | Population | (%) |
| Okinawan (USA Hawaii) | 6.3 | |
| Japan Japan Japan is an island nation in East Asia. Located in the Pacific Ocean, it lies to the east of the Sea of Japan, China, North Korea, South Korea and Russia, stretching from the Sea of Okhotsk in the north to the East China Sea and Taiwan in the south... (2) |
2.7 | |
| Tarialan Khoton (Mongolia Mongolia Mongolia is a landlocked country in East and Central Asia. It is bordered by Russia to the north and China to the south, east and west. Although Mongolia does not share a border with Kazakhstan, its western-most point is only from Kazakhstan's eastern tip. Ulan Bator, the capital and largest... ) |
2.4 | |
| South Korea South Korea The Republic of Korea , , is a sovereign state in East Asia, located on the southern portion of the Korean Peninsula. It is neighbored by the People's Republic of China to the west, Japan to the east, North Korea to the north, and the East China Sea and Republic of China to the south... (3) |
2.1 | |
| Gipuscoa Basque (Spain) | 2.0 | |
| Japan Central | 1.8 | |
| Casablanca (Morocco) | 1.8 | |
| Hyogo (Japan) | 1.6 | |
| N. Korean (Harbin,China) | 1.0 | |
| Manchu (Harbin, China) | 0.6 | |
| Naxi (Yunnan, China) | 0.6 | |
| Girona (Catalonia,Spain) | 0.6 | |
| Algeria (1) | 0.5 | |
| Inner Mongolia (China) | 0.5 | |
| Khalkha (Mongolia) | 0.5 | |
| Shanghai (China) | 0.3 | |
| Essen (German ) | 0.3 | |
| Southern Han (China) | 0.2 | |
| Shij. Tian. (Beijing, China) | 0.1 | |
| Hakka (Taiwan) | 0.1 |
| Japan |  |
| Korea |  |
| Mongolia |  |
| Heilongjiang prov., China (Harbin city) |
 |