HLA-B50
Encyclopedia
| Alleles | B*5001, B*5002, | |
| Structure (See HLA-B HLA-B HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex... ) |
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| Symbol(s) Human Genome Organisation The Human Genome Organisation is an organization involved in the Human Genome Project, a project about mapping the human genome. HUGO was established in 1989 as an international organization, primarily to foster collaboration between genome scientists around the world... |
HLA-B | |
| EBI-HLA European Bioinformatics Institute The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory... |
B*5001 | |
| B*5002 | ||
| Locus Locus (genetics) In the fields of genetics and genetic computation, a locus is the specific location of a gene or DNA sequence on a chromosome. A variant of the DNA sequence at a given locus is called an allele. The ordered list of loci known for a particular genome is called a genetic map... |
chr.6 Chromosome 6 (human) Chromosome 6 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 6 spans more than 170 million base pairs and represents between 5.5 and 6% of the total DNA in cells... 6p21.31 |
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HLA-B50 (B50) is an HLA
Human leukocyte antigen
The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...
-B
HLA-B
HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex...
serotype
Serotype
Serotype or serovar refers to distinct variations within a subspecies of bacteria or viruses. These microorganisms, viruses, or cells are classified together based on their cell surface antigens...
. B50 is a split antigen from the B21
HLA-B21
HLA-B21 is an HLA - B serotype. B21 is a broad antigen serotype that recognizes the B49 and B50 split antigen serotypes....
broad antigen, the sister serotype B49
HLA-B49
HLA-B49 is an HLA-B serotype. B49 is a split antigen from the B21 broad antigen, the sister serotype B50. The serotype identifies the more common HLA-B*50 gene products. -Serotype:...
. The serotype identifies the more common HLA-B*50 gene products. (For terminology help see: HLA-serotype tutorial)
Serotype
| B*50 | B50 | B21 | Sample |
| allele | % | % | size (N) |
| 5001 | 85 | 3 | 1700 |
The B*5002 by serotype definition is a B45 serotype.
Allele distribution
| freq | ||
| ref. | Population | (%) |
| Saudi Arabia Guraiat and Hail | 17.3 | |
| Tunisia | 10.0 | |
| Israel Arab Druse | 8.5 | |
| Morocco Nador Metalsa (Berber) | 7.3 | |
| Tunisia Tunis | 6.3 | |
| Israel Ashkenazi and Non Ashkenazi Jews | 5.5 | |
| Azores Terceira Island | 5.1 | |
| Georgia Svaneti Svans | 3.8 | |
| India North Delhi | 3.8 | |
| Italy Bergamo | 3.6 | |
| Georgia Tibilisi Kurds | 3.4 | |
| Italy North (1) | 3.3 | |
| Brazil Belo Horizonte | 3.2 | |
| Madeira | 3.2 | |
| Italy North Pavia | 3.1 | |
| Portugal South | 3.1 | |
| Oman | 3.0 | |
| Georgia Tibilisi Georgians | 2.8 | |
| Bulgaria | 2.7 | |
| Azores Santa Maria and Sao Miguel | 2.6 | |
| Spain Eastern Andalusia Gipsy | 2.5 | |
| Sudanese | 2.5 | |
| Czech Republic | 2.4 | |
| Spain Eastern Andalusia | 2.4 | |
| Spain Majorca and Minorca | 2.2 | |
| Burkina Faso Fulani | 2.0 | |
| China Inner Mongolia | 2.0 | |
| China North Han | 1.9 | |
| India North Hindus | 1.9 | |
| China Qinghai Hui | 1.8 | |
| Jordan Amman | 1.7 | |
| Russia Tuva (2) | 1.7 | |
| Spain Catalonia Girona | 1.7 | |
| Senegal Niokholo Mandenka | 1.6 | |
| Guinea Bissau | 1.5 | |
| India New Delhi | 1.5 | |
| Croatia | 1.3 | |
| Cuban Mulatto | 1.2 | |
| France South East | 1.2 | |
| Burkina Faso Rimaibe | 1.1 | |
| Mali Bandiagara | 1.1 | |
| Belgium | 1.0 | |
| Ireland Northern | 1.0 | |
| Ireland South | 1.0 | |
| Italy Sardinia pop3 | 1.0 | |
| South Africa Natal Tamil | 1.0 | |
| B*5002 | ||
| Morocco Nador Metalsa (Berber) | 4.3 | |
| Portugal North | 1.1 | |
| Portugal South | 1.0 | |
| Madeira | 0.8 | |
| Tunisia Tunis | 0.6 | |