HLA-B (alpha)-β2MG with bound peptide
Alleles	B*4501, 4502 . .
Structure (See HLA-B HLA-B HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex... )
Shared data
Locus Locus (genetics) In the fields of genetics and genetic computation, a locus is the specific location of a gene or DNA sequence on a chromosome. A variant of the DNA sequence at a given locus is called an allele. The ordered list of loci known for a particular genome is called a genetic map...	chr.6 Chromosome 6 (human) Chromosome 6 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 6 spans more than 170 million base pairs and represents between 5.5 and 6% of the total DNA in cells...  6p21.31

HLA-B45 (B45) is an HLA

Human leukocyte antigen

The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...

-B

HLA-B

HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex...

 serotype

Serotype

Serotype or serovar refers to distinct variations within a subspecies of bacteria or viruses. These microorganisms, viruses, or cells are classified together based on their cell surface antigens...

. The serotype identifies the B*45 gene-allele protein products of HLA-B.
B45 is a split antigen of the broad antigen B12

HLA-B12

HLA-B12 is an HLA - B serotype. B12 is a broad antigen serotype that recognizes the B44 and B45 split antigen serotypes....

, and is a sister type of B44

HLA-B44

HLA-B44 is an HLA-B serotype. The serotype identifies the B*44 gene-allele protein products of HLA-B.B44 is a split antigen of the broad antigen B12, and is a sister type of B45.-Serotype:-Disease:...

.

Serotype

Serotypes B45, B12, and B44 recognition of the
HLA B*44 gene products

B*45	B45	B12	B45	Sample
allele	%	%	%	size (N)
	93	1	1	2307
	75			4
Alleles link-out to IMGT/HLA Human leukocyte antigen The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...  Databease at EBI European Bioinformatics Institute The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory...

Alleles

It was reported that a novel haplotype was found in Italian bone marrow doners. A2-CW*1601-B45- DRB1*1101-DRB3*0301-DQA1*0102-DQB1*0502. This haplotype indicates possible very recent ancestry from Africa, with the Cw*1601 and B45 components and also with the DR11-DQ5.2 component both extremely rare in Europe.