HLA-B (alpha)-β2MG with bound peptide
Alleles	B*4401, 4402, 4403 . .
Structure (See HLA-B HLA-B HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex... )
Shared data
Locus Locus (genetics) In the fields of genetics and genetic computation, a locus is the specific location of a gene or DNA sequence on a chromosome. A variant of the DNA sequence at a given locus is called an allele. The ordered list of loci known for a particular genome is called a genetic map...	chr.6 Chromosome 6 (human) Chromosome 6 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 6 spans more than 170 million base pairs and represents between 5.5 and 6% of the total DNA in cells...  6p21.31

HLA-B44 (B44) is an HLA

Human leukocyte antigen

The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...

-B

HLA-B

HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex...

 serotype

Serotype

Serotype or serovar refers to distinct variations within a subspecies of bacteria or viruses. These microorganisms, viruses, or cells are classified together based on their cell surface antigens...

. The serotype identifies the B*44 gene-allele protein products of HLA-B.
B44 is a split antigen of the broad antigen B12

HLA-B12

HLA-B12 is an HLA - B serotype. B12 is a broad antigen serotype that recognizes the B44 and B45 split antigen serotypes....

, and is a sister type of B45

HLA-B45

HLA-B45 is an HLA-B serotype. The serotype identifies the B*45 gene-allele protein products of HLA-B.B45 is a split antigen of the broad antigen B12, and is a sister type of B44.-Serotype:-Alleles:...

.

Serotype

Serotypes B44, B12, and B45 recognition of the
HLA B*44 gene products

B*44	B44	B12	B45	Sample
allele	%	%	%	size (N)
	98			6959
	94			2854
	65			42
	92			130
	44			9
B*4401 was shown to be B*4402 after errors corrected.
Alleles link-out to IMGT/HLA Human leukocyte antigen The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...  Database at EBI European Bioinformatics Institute The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory...

Disease

HLA-B44 increases recurrent sinopulmonary infections. Protective effects: HLA-B44 appears to be protective against autoimmune lymphoproliferative syndrome in patients with C95 defect (ALPS type Ia). B44 may be a cofactor in ankylosing spondylitis

Ankylosing spondylitis

Ankylosing spondylitis , previously known as Bekhterev's disease, Bekhterev syndrome, and Marie-Strümpell disease is a chronic inflammatory disease of the axial skeleton with variable involvement of peripheral joints and nonarticular structures...