Douglas Jabs
Encyclopedia
Douglas Jabs, M.D., M.B.A., is an American
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...

 ophthalmologist
Ophthalmology
Ophthalmology is the branch of medicine that deals with the anatomy, physiology and diseases of the eye. An ophthalmologist is a specialist in medical and surgical eye problems...

 and an expert in clinical research in the fields of ophthalmology and uveitis
Uveitis
Uveitis specifically refers to inflammation of the middle layer of the eye, termed the "uvea" but in common usage may refer to any inflammatory process involving the interior of the eye....

.

Jabs is currently the Chief Executive Officer of the Mount Sinai Faculty Practice Associates, Dean for Clinical Affairs, and Professor and Chair of the Department of Ophthalmology and Professor of Medicine of The Mount Sinai School of Medicine
Mount Sinai School of Medicine
Mount Sinai School of Medicine is an American medical school in the borough of Manhattan in New York City, currently ranked among the top 20 medical schools in the United States. It was chartered by Mount Sinai Hospital in 1963....

 in New York City
New York City
New York is the most populous city in the United States and the center of the New York Metropolitan Area, one of the most populous metropolitan areas in the world. New York exerts a significant impact upon global commerce, finance, media, art, fashion, research, technology, education, and...

. Additionally, he is adjunct Professor of Epidemiology at the Johns Hopkins Bloomberg School of Public Health
Johns Hopkins Bloomberg School of Public Health
The Johns Hopkins Bloomberg School of Public Health is part of Johns Hopkins University in Baltimore, Maryland, United States...

 in Baltimore
Baltimore
Baltimore is the largest independent city in the United States and the largest city and cultural center of the US state of Maryland. The city is located in central Maryland along the tidal portion of the Patapsco River, an arm of the Chesapeake Bay. Baltimore is sometimes referred to as Baltimore...

, Maryland
Maryland
Maryland is a U.S. state located in the Mid Atlantic region of the United States, bordering Virginia, West Virginia, and the District of Columbia to its south and west; Pennsylvania to its north; and Delaware to its east...

.

He is the author or co–author of over 230 publications, 45 books chapters and 86 published abstracts.

Biography

Jabs graduated valedictorian
Valedictorian
Valedictorian is an academic title conferred upon the student who delivers the closing or farewell statement at a graduation ceremony. Usually, the valedictorian is the highest ranked student among those graduating from an educational institution...

 from Dartmouth College
Dartmouth College
Dartmouth College is a private, Ivy League university in Hanover, New Hampshire, United States. The institution comprises a liberal arts college, Dartmouth Medical School, Thayer School of Engineering, and the Tuck School of Business, as well as 19 graduate programs in the arts and sciences...

 in 1973 with a degree in chemistry
Chemistry
Chemistry is the science of matter, especially its chemical reactions, but also its composition, structure and properties. Chemistry is concerned with atoms and their interactions with other atoms, and particularly with the properties of chemical bonds....

. He received his medical degree from Johns Hopkins School of Medicine
Johns Hopkins School of Medicine
The Johns Hopkins School of Medicine , located in Baltimore, Maryland, U.S., is the academic medical teaching and research arm of Johns Hopkins University. Hopkins has consistently been the nation's number one medical school in the amount of competitive research grants awarded by the National...

 in 1977. He completed an internship in internal medicine
Internal medicine
Internal medicine is the medical specialty dealing with the prevention, diagnosis, and treatment of adult diseases. Physicians specializing in internal medicine are called internists. They are especially skilled in the management of patients who have undifferentiated or multi-system disease processes...

 at New York Hospital–Cornell Medical Center, a residency in internal medicine at The Johns Hopkins Hospital
Johns Hopkins Hospital
The Johns Hopkins Hospital is the teaching hospital and biomedical research facility of Johns Hopkins University School of Medicine, located in Baltimore, Maryland . It was founded using money from a bequest by philanthropist Johns Hopkins...

 and a residency in ophthalmology at the Wilmer Eye Institute, and a rheumatology
Rheumatology
Rheumatology is a sub-specialty in internal medicine and pediatrics, devoted to diagnosis and therapy of rheumatic diseases. Clinicians who specialize in rheumatology are called rheumatologists...

 fellowship at Johns Hopkins.

Jabs joined the faculty at the Johns Hopkins School of Medicine in 1984 as Assistant Professor. He was named Associate Professor of Ophthalmology in 1988, and Associate Professor of Medicine in 1989. In 1993 he was named Professor of both Ophthalmology and Medicine, and in 2000 he was named Professor of Epidemiology at the Bloomberg School of Public Health. In 2007, he was named Professor and Chair of the Department of Ophthalmology at The Mount Sinai Medical Center. In 2009, he was chosen as the Chief Executive Officer of the Mount Sinai Faculty Practice Associates and Dean for Clinical Affairs of the Mount Sinai School of Medicine.

Jabs currently chairs both the Study of Ocular Complications of AIDS (SOCA) Research Group and the Multicenter Uveitis Steroid Treatment (MUST) Trial. He has chaired five randomized, controlled, clinical trials on the treatment of CMV retinitis
Cytomegalovirus retinitis
Cytomegalovirus retinitis, also known as CMV retinitis, is an inflammation of the eye's retina that can lead to blindness.-Presentation:...

 and now chairs a multicenter
Multicenter trial
A multicenter research trial is a clinical trial conducted at more than one medical center or clinic. Most large clinical trials, particularly Phase III trials, are conducted at several clinical research centers...

 epidemiologic study investigating the long–term outcomes of patients with ocular complications of AIDS
AIDS
Acquired immune deficiency syndrome or acquired immunodeficiency syndrome is a disease of the human immune system caused by the human immunodeficiency virus...

, particularly CMV retinitis. Jabs has been instrumental in leading the Standardization of Uveitis (SUN) project, an effort to standardize terminology and outcomes related to uveitis. He has served on numerous data and safety monitoring committees for clinical trials, both those sponsored by the National Institutes of Health
National Institutes of Health
The National Institutes of Health are an agency of the United States Department of Health and Human Services and are the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation...

 and the pharmaceutical industry.

Affiliations

  • 1980 – American Association for the Advancement of Science
    American Association for the Advancement of Science
    The American Association for the Advancement of Science is an international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific responsibility, and supporting scientific education and science outreach for the...

  • 1981 – Association for Research in Vision and Ophthalmology
  • 1982 – Fellow, American Academy of Ophthalmology
    American Academy of Ophthalmology
    The American Academy of Ophthalmology is the largest national membership medical association of ophthalmologists–medical doctors specializing in eye care and surgery including medical, surgical and optical care. More than 90 percent of practicing U.S. Eye M.D.s are Academy members, and the...

  • 1985 – American Uveitis Society
  • 1985 – Ocular Microbiology and Immunology Group
  • 1985 – Fellow, American College of Rheumatology
    American College of Rheumatology
    The American College of Rheumatology is an organization of and for physicians, health professionals, and scientists that advances rheumatology through programs of education, research, advocacy and practice support that foster excellence in the care of people with arthritis and rheumatic and...

  • 1990 – The Macula Society
  • 1995 – American Ophthalmological Society
  • 1998 – International Uveitis Study Group
  • 2000 – Society for Clinical Trials
  • 2001 – The Retina Society
  • 2001 – American Society of Retina Specialist
  • 2008 – New York Ophthalmologic Society
  • 2008 – Manhattan Ophthalmologic Society
  • 2009 – Ophthalmic Laser Surgery Society, New York

Editorial appointments

  • 1989–present – Retina – The Journal of Retinal and Vitreous Diseases, Editorial Board
  • 1999–present – Ocular Immunology and Inflammation, Editorial Board
  • 2002–present – American Journal of Ophthalmology, Editorial Board
  • 2002-2007 – American Journal of Ophthalmology, Executive Editor
  • 2008-2009 – Ophthalmic Epidemiology, Editorial Board


Additionally, Jabs is a reviewer for the American Journal of Ophthalmology, Annals of Internal Medicine
Annals of Internal Medicine
Annals of Internal Medicine is an academic medical journal published by the American College of Physicians . It publishes research articles and reviews in the area of internal medicine. Its current editor is Christine Laine...

, Archives of Ophthalmology
Archives of Ophthalmology
The Archives of Ophthalmology is a monthly professional medical journal published by the American Medical Association. Archives of Ophthalmology publishes peer-reviewed, original articles on such topics as epidemiology and biostatistics, mechanisms of ophthalmic disease, ophthalmic molecular...

, Current Eye Research, Investigative Ophthalmology & Visual Science
Investigative Ophthalmology & Visual Science
Investigative Ophthalmology & Visual Science , published as ready online, is a peer-reviewed academic journal of the Association for Research in Vision and Ophthalmology . IOVS features original research, mostly pertaining to clinical and laboratory ophthalmology and vision research in general...

, Journal of American Medical Association, Journal of Immunology
Journal of Immunology
The Journal of Immunology is a peer-reviewed academic journal that publishes basic and clinical studies in all aspects of immunology. It was founded by Arthur Fernandez Coca in 1915 . It is the official journal of The American Association of Immunologists and published by The American Association...

, Journal of Infectious Disease, Medicine, New England Journal of Medicine
New England Journal of Medicine
The New England Journal of Medicine is an English-language peer-reviewed medical journal published by the Massachusetts Medical Society. It describes itself as the oldest continuously published medical journal in the world.-History:...

, Ophthalmic Epidemiology, Ophthalmology
Ophthalmology (journal)
Ophthalmology is a peer-reviewed medical journal published by the American Academy of Ophthalmology.Topics include new diagnostic and surgical techniques, treatment methods, instrument updates, the latest drug findings, results of clinical trials, and research findings. Ophthalmology also publishes...

, Retina, and Survey of Ophthalmology
Survey of Ophthalmology
Survey of Ophthalmology is a review journal dedicated to publishing reviews of ophthalmological topics by established authorities in that particular field. It is a strictly refereed journal with a bi-monthly publication schedule...

.

Awards and honors

  • 1986-1987 – Johns Hopkins University Clinician Scientist Award
  • 1991 – Research to Prevent Blindness Olga Keith Weiss Scholar Award
  • 1997 – Research to Prevent Blindness Lew R. Wasserman Merit Award
  • 2002 – Research to Prevent Blindness Senior Scientific Investigator
  • 2005 – American Academy of Ophthalmology Senior Achievement Award
  • 2007 – Clinical Uveitis Research Award from the German Uveitis Patient Interest Group
  • 2008 – EyeCare America, Lifetime Volunteer Physician Award
  • 2009 – European Uveitis Patient Interest Association (EUPIA) Uveitis Award

Publications

  • Jabs DA. Acyclovir for recurrent herpes simplex virus ocular disease. N Engl J Med 1998;339:340–341. PMID 9682049

  • Jabs, DA, Rosenbaum JT, Foster CS, Holland GN, Jaffe GJ, Louie JS, Nussenblatt RB, Stiehm RE, Tessler H, Van Gelder RN, Whitcup SM, Yocum D. Guidelines for the use of immunosuppressive drugs in patients with ocular inflammatory disorders: recommendations of an expert panel. Am J Ophthalmol 2000;130:492–513. PMID 11354352

  • Jabs DA, Mudun A, Dunn JP, Marsh MJ. Episcleritis and scleritis: clinical features and treatment results. Am J Ophthalmol 2000;130:469–476. PMID 11024419

  • Jabs DA, Martin BK, Forman MS, Hubbard L, Dunn JP, Kempen JH, Davis JL, Weinberg DV, for the Cytomegalovirus Retinitis and Viral Resistance Study Group. Cytomegalovirus resistance to ganciclovir and clinical outcomes of patients with cytomegalovirus retinitis. Am J Ophthalmol 2003;135:26–34. PMID 12504693

  • Jabs DA, Holbrook JT, Van Natta ML, Clark R, Jacobson MA, Kempen JH, Murphy RL, for the Studies of Ocular Complications of AIDS Research Group. Risk factors for mortality in patients with AIDS in the era of highly active antiretroviral therapy. Ophthalmology 2005;112:771–779. PMID 15878056

  • Thorne JE, Jabs DA, Peters GB, Hair D, Dunn JP, Kempen JH. Birdshot retinochoroidopathy: ocular complications and visual impairment. Am J Ophthalmol 2005;140:45–51. PMID 16038650

  • The Standardization of Uveitis Nomenclature (SUN) Working Group. Standardization of uveitis nomenclature for reporting clinical data. Results of the first international workshop. Am J Ophthalmol 2005;140:509–516. PMID 16196117

  • Thorne JE, Wittenberg SE, Jabs DA, Peters GB, Kedhar SR, Dunn JP. Multifocal choroiditis with panuveitis: incidence of ocular complications and loss of visual acuity. Ophthalmology 2006;113:2310–2316. PMID 16996607

  • Thorne JE, Jabs DA, Kedhar SR, Peters GB, Dunn JP. Loss of visual field among patients with birdshot chorioretinopathy. Am J Ophthalmol 2008;145:23–28. PMID 17997394

  • Jabs DA. AIDS and ophthalmology, 2008. Arch Ophthalmol 2008;126:1143–1146. PMID 18695113

  • Galor A, Jabs DA, Leder HA, Kedhar SR, Dunn JP, Thorne JE. Comparison of antimetabolite drugs as corticosteroid–sparing therapy for noninfectious ocular inflammation. Ophthalmology 2008;115:1826–1832. PMID 18579209

  • Kempen JH, Daniel E, Dunn JP, Foster CS, Gangaputra S, Hanish A, Helzlsouer KJ, Jabs DA, Kaçmaz RO, Levy–Clarke GA, Liesegang TL, Newcomb CW, Nussenblatt RB, Pujari SS, Rosenbaum JT, Suhler EB, Thorne JE. Overall and cancer related mortality among patients with ocular inflammation treated with immunosuppressive therapy: retrospective cohort study. Brit Med J 2009;339:b2480. PMID 19578087

  • Jabs DA, Martin BK, Forman MS, for the Cytomegalovirus Retinitis and Viral Resistance Research Group. Mortality associated with resistant cytomegalovirus among patients with cytomegalovirus retinitis and AIDS. Ophthalmology. PMID 19818505

External links

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