Cambridge Isotope Laboratories (CIL) is a company which manufacturer and sells a variety of isotopically labeled chemicals and analytical standards. Its isotope separation facility is located in Xenia, Ohio

Xenia, Ohio

Xenia is a city in and the county seat of Greene County, Ohio, United States. The municipality is located in southwestern Ohio 21 miles from Dayton and is part of the Dayton Metropolitan Statistical Area...

 and its production laboratories are located in Andover, Massachusetts

Andover, Massachusetts

Andover is a town in Essex County, Massachusetts, United States. It was incorporated in 1646 and as of the 2010 census, the population was 33,201...

. The company employs approximately 130 people and only develops compounds with stable (non-radioactive) isotopes.

Isotopes

CIL primarily sells chemical compounds that contain very high percentages of deuterium

Deuterium

Deuterium, also called heavy hydrogen, is one of two stable isotopes of hydrogen. It has a natural abundance in Earth's oceans of about one atom in of hydrogen . Deuterium accounts for approximately 0.0156% of all naturally occurring hydrogen in Earth's oceans, while the most common isotope ...

, carbon-13

Carbon-13

Carbon-13 is a natural, stable isotope of carbon and one of the environmental isotopes. It makes up about 1.1% of all natural carbon on Earth.- Detection by mass spectrometry :...

, nitrogen-15, and oxygen-18

Oxygen-18

Oxygen-18 is a natural, stable isotope of oxygen and one of the environmental isotopes.18O is an important precursor for the production of fluorodeoxyglucose used in positron emission tomography...

. They also sells compounds that are over 99.9% in carbon-12

Carbon-12

Carbon-12 is the more abundant of the two stable isotopes of the element carbon, accounting for 98.89% of carbon; it contains 6 protons, 6 neutrons, and 6 electrons....

 so as to exclude carbon-13. Certain isotopes of some main group

Main group element

In chemistry and atomic physics, main group elements are elements in groups whose lightest members are represented by helium, lithium,...

 and transition metals are also sold, usually as either oxides or as the pure metal.

Classes of Products

For NMR spectroscopy, CIL sells a wide array of deuterated solvents (molecules where all hydrogens have been replaced by deuteriums) and oxygen-18 water. They also market several isotopically labeled gases such as acetylene, carbon monoxide, methane, and others.

For biological studies

Biology

Biology is a natural science concerned with the study of life and living organisms, including their structure, function, growth, origin, evolution, distribution, and taxonomy. Biology is a vast subject containing many subdivisions, topics, and disciplines...

, the company sells many labelled amino acids and growth media. Molecules important to biochemistry, such as d-glucose and sodium pyruvate

Sodium pyruvate

Sodium pyruvate is commonly added to cell culture media as an additional source of energy, but may also have protective effects against hydrogen peroxide. This was reported by Giandomenico et al.. and has been confirmed by several independent groups....

, are also available in labelled form.

CIL also sells a large array of analytical standards in both labelled and unlabelled form. Some are general pollutants that can originate from many different sources: dioxins

Dioxin

Polychlorinated dibenzodioxins , or simply dioxins, are a group of organic polyhalogenated compounds that are significant environmental pollutants. They are commonly but inaccurately referred to as dioxins for simplicity, because every PCDD molecule contains a dioxin skeletal structure as the...

, furans

Furan

Furan is a heterocyclic organic compound, consisting of a five-membered aromatic ring with four carbon atoms and one oxygen. The class of compounds containing such rings are also referred to as furans....

, pesticides, PCBs, and PAHs. Other analytical standards are made for chemicals found particular products: pharmaceuticals, tobacco products, and flame retardants. Some metabolites of phthalates

Phthalates

Phthalates , or phthalate esters, are esters of phthalic acid and are mainly used as plasticizers . They are used primarily to soften polyvinyl chloride...

, tobacco, pesticides, and chemical weapons are also available.