CSNK2A1
Encyclopedia
Casein kinase II subunit alpha is an enzyme
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...

 that in humans is encoded by the CSNK2A1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

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Interactions

Casein kinase 2, alpha 1 has been shown to interact
Protein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...

 with CHEK1
CHEK1
Serine/threonine-protein kinase Chk1 is an enzyme that in humans is encoded by the CHEK1 gene.Chk1 is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216 by chk1 becomes bound by an adaptor...

, FGF1
FGF1
Heparin-binding growth factor 1 is a protein that in humans is encoded by the FGF1 gene.-Interactions:FGF1 has been shown to interact with CSNK2B, CSNK2A2, HSPA9, S100A13, Casein kinase 2, alpha 1, Fibroblast growth factor receptor 1, FIBP, Fibroblast growth factor receptor 4, Fibroblast growth...

, CDC25B
CDC25B
M-phase inducer phosphatase 2 is an enzyme that in humans is encoded by the CDC25B gene.-Interactions:CDC25B has been shown to interact with MAPK14, Casein kinase 2, alpha 1, CHEK1, MELK, Estrogen receptor alpha, YWHAB, YWHAZ, YWHAH and YWHAE....

, CREB-binding protein, Activating transcription factor 2
Activating transcription factor 2
Activating transcription factor 2, also known as ATF2, is a protein that, in humans, is encoded by the ATF2 gene.-Function:This gene encodes a transcription factor that is a member of the leucine zipper family of DNA-binding proteins. This protein binds to the cAMP-responsive element , an octameric...

, C-Fos
C-Fos
In the field of molecular biology and Genetics, c-Fos is a protein encoded by the FOS gene.-Structure and function:c-Fos is a cellular proto-oncogene belonging to the immediate early gene family of transcription factors. c-Fos has a leucine-zipper DNA binding domain, and a transactivation domain at...

, MAPK14
MAPK14
Mitogen-activated protein kinase 14, also called p38-α, is an enzyme that in humans is encoded by the MAPK14 gene.-Interactions:MAPK14 has been shown to interact with Casein kinase 2, alpha 1, RPS6KA4, MAPKAPK2, CDC25B, DUSP1, ZFP36L1, CDC25C, MAPKAPK3, Activating transcription factor 2, MAPK1,...

, RELA
RELA
Transcription factor p65 is a protein that in humans is encoded by the RELA gene.-Interactions:RELA has been shown to interact with NFKBIB, ETHE1, NFKBIE, RFC1, TRIB3, CREB binding protein, Neutrophil cytosolic factor 1, Glucocorticoid receptor, MTPN, BRCA1, C-Fos, POU2F1, BTRC, TATA-binding...

, PIN1
PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 is an enzyme that in humans is encoded by the PIN1 gene.-Interactions:PIN1 has been shown to interact with CSNK2A2, Casein kinase 2, alpha 1, Wee1-like protein kinase, FOXO4, CDC25C, CDC27, MYT1, PLK1, MPHOSPH1, DAB2, P53, PKMYT1, C-jun,...

, PLEKHO1
PLEKHO1
Pleckstrin homology domain-containing family O member 1 is a protein that in humans is encoded by the PLEKHO1 gene.-Interactions:PLEKHO1 has been shown to interact with Casein kinase 2, alpha 1 and SMURF1.-Further reading:...

, CSNK2B
CSNK2B
Casein kinase, a ubiquitous, well-conserved protein kinase involved in cell metabolism and differentiation, is characterised by its preference for Serine or Threonine in acidic stretches of amino acids. The enzyme is a tetramer of 2 alpha- and 2 beta-subunits...

, PTEN
PTEN (gene)
Phosphatase and tensin homolog is a protein that, in humans, is encoded by the PTEN gene. Mutations of this gene are a step in the development of many cancers....

, ATF1
ATF1
Cyclic AMP-dependent transcription factor ATF-1 is a protein that in humans is encoded by the ATF1 gene.-Interactions:ATF1 has been shown to interact with CSNK2A2, Casein kinase 2, alpha 1 and BRCA1. EWS,- External links :...

, TAF1
TAF1
Transcription initiation factor TFIID subunit 1, also known as transcription initiation factor TFIID 250 kDa subunit or TBP-associated factor 250 kDa , is a protein that in humans is encoded by the TAF1 gene.-Function:...

, UBTF
UBTF
Nucleolar transcription factor 1 is a protein that in humans is encoded by the UBTF gene.-Interactions:UBTF has been shown to interact with Casein kinase 2, alpha 1, TAF1C, Retinoblastoma protein and TAF1.-Further reading:...

, DNA damage-inducible transcript 3
DNA damage-inducible transcript 3
DNA damage-inducible transcript 3 is a protein that in humans is encoded by the DDIT3 gene.-Interactions:DNA damage-inducible transcript 3 has been shown to interact with Casein kinase 2, alpha 1, JunD, RPS3A, ATF3, CEBPB, C-jun and C-Fos....

, Basic fibroblast growth factor
Basic fibroblast growth factor
Basic fibroblast growth factor, also known as bFGF, FGF2 or FGF-β, is a member of the fibroblast growth factor family.- Function :...

, APC
APC (gene)
Adenomatous polyposis coli also known as deleted in polyposis 2.5 is a protein that in humans is encoded by the APC gene. Mutations in the APC gene may result in colorectal cancer....

, HNRPA2B1
HNRPA2B1
Heterogeneous nuclear ribonucleoproteins A2/B1 is a protein that in humans is encoded by the HNRNPA2B1 gene.HnRNPA2B1 is an autoantigen in autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus and mixed connective tissue disease...

 and C-jun
C-jun
c-Jun is the name of a gene and protein that, in combination with c-Fos, forms the AP-1 early response transcription factor. It was first identified as the Fos-binding protein p39 and only later rediscovered as the product of the c-jun gene. It is activated through double phosphorylation by the...

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Further reading

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