U.S. Route 150 is a 571 mile (919 km) long northwest-southeast United States highway, signed as east–west. It runs from U.S. Route 6

U.S. Route 6

U.S. Route 6 , also called the Grand Army of the Republic Highway, a name that honors an American Civil War veterans association, is a main route of the U.S. Highway system, running east-northeast from Bishop, California to Provincetown, Massachusetts. Until 1964, it continued south from Bishop to...

 outside of Moline, Illinois

Moline, Illinois

Moline is a city located in Rock Island County, Illinois, United States, with a population of 45,792 in 2010. Moline is one of the Quad Cities, along with neighboring East Moline and Rock Island in Illinois and the cities of Davenport and Bettendorf in Iowa. The Quad Cities has a population of...

 to U.S. Route 25

U.S. Route 25

U.S. Route 25 is a north–south United States highway that runs for from Brunswick, Georgia to the Ohio state line in Covington, Kentucky.-Georgia:...

 in Mount Vernon, Kentucky

Mount Vernon, Kentucky

Mount Vernon is a city in Rockcastle County, Kentucky, United States. The population was 2,592 at the 2000 census. It is the county seat of Rockcastle County. It is located at the junction of U.S...

 .

Illinois

In the state of Illinois

Illinois

Illinois is the fifth-most populous state of the United States of America, and is often noted for being a microcosm of the entire country. With Chicago in the northeast, small industrial cities and great agricultural productivity in central and northern Illinois, and natural resources like coal,...

, U.S. 150 runs from the Quad City International Airport

Quad City International Airport

Quad City International Airport is a public airport located three miles south of the central business district of Moline, a city in Rock Island County, Illinois, United States. It is owned by the Metropolitan Airport Authority...

 at U.S. Route 6

U.S. Route 6

U.S. Route 6 , also called the Grand Army of the Republic Highway, a name that honors an American Civil War veterans association, is a main route of the U.S. Highway system, running east-northeast from Bishop, California to Provincetown, Massachusetts. Until 1964, it continued south from Bishop to...

 southeast to near Vermilion

Vermilion, Illinois

Vermilion is a village in Stratton and Elbridge Township townships, Edgar County, Illinois, United States. The population was 225 at the 2010 census.-Geography:Vermilion is located at , about 3 miles west of the border with Indiana...

. U.S. 150 in Illinois is 267.47 miles (430.45 km) long.

Between Moline and Danville, Route 150 closely parallels Interstate 74

Interstate 74

Interstate 74 is an Interstate Highway in the Midwestern and Southeastern United States. Its western end is at an intersection with Interstate 80 in Davenport, Iowa; the eastern end of its Midwest segment is at an intersection with Interstate 75 in Cincinnati, Ohio...

.

Indiana

In the state of Indiana

Indiana

Indiana is a US state, admitted to the United States as the 19th on December 11, 1816. It is located in the Midwestern United States and Great Lakes Region. With 6,483,802 residents, the state is ranked 15th in population and 16th in population density. Indiana is ranked 38th in land area and is...

, U.S. 150 runs south with U.S. Route 41

U.S. Route 41

U.S. Route 41 is a north–south United States Highway that runs from Miami, Florida to the Upper Peninsula of Michigan. Until 1949, the part in southern Florida, from Naples to Miami, was U.S...

 from Terre Haute

Terre Haute, Indiana

Terre Haute is a city and the county seat of Vigo County, Indiana, United States, near the state's western border with Illinois. As of the 2010 census, the city had a total population of 60,785 and its metropolitan area had a population of 170,943. The city is the county seat of Vigo County and...

. It is then concurrent with its parent, U.S. Route 50

U.S. Route 50

U.S. Route 50 is a major east–west route of the U.S. Highway system, stretching just over from Ocean City, Maryland on the Atlantic Ocean to West Sacramento, California. Until 1972, when it was replaced by Interstate Highways west of the Sacramento area, it extended to San Francisco, near...

 from Vincennes

Vincennes, Indiana

Vincennes is a city in and the county seat of Knox County, Indiana, United States. It is located on the Wabash River in the southwestern part of the state. The population was 18,701 at the 2000 census...

 to Shoals

Shoals, Indiana

Shoals is a town in Center and Halbert townships, Martin County, Indiana, United States. The population was 756 at the 2010 census. The city is the county seat of Martin County....

. It then runs east to New Albany

New Albany, Indiana

New Albany is a city in Floyd County, Indiana, United States, situated along the Ohio River opposite Louisville, Kentucky. In 1900, 20,628 people lived in New Albany; in 1910, 20,629; in 1920, 22,992; and in 1940, 25,414. The population was 36,372 at the 2010 census. The city is the county seat of...

 before overlapping Interstate 64

Interstate 64

Interstate 64 is an Interstate Highway in the Midwestern and Southeastern United States. Its western terminus is at I-70, U.S. 40, and U.S. 61 in Wentzville, Missouri. Its eastern terminus is at an interchange with I-264 and I-664 at Bowers Hill in Chesapeake, Virginia. As I-64 is concurrent with...

 into Kentucky. Between Vincennes and New Albany the road follows the original route of the Buffalo Trace

Buffalo Trace (road)

The Buffalo Trace was a trackway running through what are now the American states of Kentucky, Indiana, and Illinois. Originally formed by migrating bison, the trace crossed the Ohio River near the Falls of the Ohio and the Wabash River near Vincennes...

.

Kentucky

U.S. 150 runs with I-64 entering Kentucky

Kentucky

The Commonwealth of Kentucky is a state located in the East Central United States of America. As classified by the United States Census Bureau, Kentucky is a Southern state, more specifically in the East South Central region. Kentucky is one of four U.S. states constituted as a commonwealth...

 from Indiana, crossing the Ohio River

Ohio River

The Ohio River is the largest tributary, by volume, of the Mississippi River. At the confluence, the Ohio is even bigger than the Mississippi and, thus, is hydrologically the main stream of the whole river system, including the Allegheny River further upstream...

 on the Sherman Minton Bridge

Sherman Minton Bridge

The Sherman Minton Bridge is a double-deck through arch bridge spanning the Ohio River, carrying I-64 and US 150 over the river between Kentucky and Indiana. The bridge connects the west side of Louisville, Kentucky to downtown New Albany, Indiana.- History :...

. It then forms a major southeastern radial artery from downtown Louisville

Louisville, Kentucky

Louisville is the largest city in the U.S. state of Kentucky, and the county seat of Jefferson County. Since 2003, the city's borders have been coterminous with those of the county because of a city-county merger. The city's population at the 2010 census was 741,096...

, called Bardstown Road and intersecting with Interstates 65

Interstate 65

Interstate 65 is a major Interstate Highway in the United States. The southern terminus is located at an intersection with Interstate 10 in Mobile, Alabama, and its northern terminus is at an interchange with Interstate 90 , U.S. Route 12, and U.S...

, 264

Interstate 264 (Kentucky)

The Henry Watterson Expressway, also known as the Georgia Davis Powers/Shawnee Expressway west of US 31W, is one of two Interstate Highways in the United States designated as Interstate 264 . It is 22.93 miles in length, and runs an open circle around central Louisville, Kentucky...

 and 265.

For its length in Louisville, U.S. 150 is also concurrent with U.S. Route 31E

U.S. Route 31E

U.S. Route 31E is the easternmost of two parallel routes for U.S. Highway 31 from Nashville, Tennessee, to Louisville, Kentucky. U.S. Route 31E is the easternmost of two parallel routes for U.S. Highway 31 from Nashville, Tennessee, to Louisville, Kentucky. U.S. Route 31E is the easternmost of two...

. They separate at Bardstown

Bardstown, Kentucky

As of the census of 2010, there were 11,700 people, 4,712 households, and 2,949 families residing in the city. The population density was . There were 5,113 housing units at an average density of...

 near the Martha Layne Collins Blue Grass Parkway. U.S. 150 then continues southeast, around the city of Danville

Danville, Kentucky

Danville is a city in and the county seat of Boyle County, Kentucky, United States. The population was 16,218 at the 2010 census.Danville is the principal city of the Danville Micropolitan Statistical Area, which includes all of Boyle and Lincoln counties....

 before terminating at Mount Vernon

Mount Vernon, Kentucky

Mount Vernon is a city in Rockcastle County, Kentucky, United States. The population was 2,592 at the 2000 census. It is the county seat of Rockcastle County. It is located at the junction of U.S...

.

History

U.S. Route 168 was created in 1926 from Louisville

Louisville, Kentucky

Louisville is the largest city in the U.S. state of Kentucky, and the county seat of Jefferson County. Since 2003, the city's borders have been coterminous with those of the county because of a city-county merger. The city's population at the 2010 census was 741,096...

 to Mount Vernon, Kentucky

Mount Vernon, Kentucky

Mount Vernon is a city in Rockcastle County, Kentucky, United States. The population was 2,592 at the 2000 census. It is the county seat of Rockcastle County. It is located at the junction of U.S...

, overlapping US 68 between Bardstown and Perryville. In 1934, US 150 absorbed US 168.

Illinois Route 39 ran from Bloomington

Bloomington, Illinois

Bloomington is a city in McLean County, Illinois, United States and the county seat. It is adjacent to Normal, Illinois, and is the more populous of the two principal municipalities of the Bloomington-Normal metropolitan area...

 to Champaign

Champaign, Illinois

Champaign is a city in Champaign County, Illinois, in the United States. The city is located south of Chicago, west of Indianapolis, Indiana, and 178 miles northeast of St. Louis, Missouri. Though surrounded by farm communities, Champaign is notable for sharing the campus of the University of...

 on the current routing of U.S. 150.

See also

• U.S. Route 50
  U.S. Route 50
  U.S. Route 50 is a major east–west route of the U.S. Highway system, stretching just over from Ocean City, Maryland on the Atlantic Ocean to West Sacramento, California. Until 1972, when it was replaced by Interstate Highways west of the Sacramento area, it extended to San Francisco, near...
  
  
• U.S. Route 250
  U.S. Route 250
  U.S. Route 250 is a route of the United States Numbered Highway System, and is a spur of U.S. Route 50. It currently runs for from Sandusky, Ohio to Richmond, Virginia. It passes through the states of Virginia, West Virginia, and Ohio. It goes through the cities of Richmond, Virginia,...
  
  
• U.S. Route 350
  U.S. Route 350
  U.S. Highway 350 is a long northeast-southwest United States highway located entirely within the state of Colorado.-Route description:US 350 starts at a junction with northeast of Trinidad, Colorado. The highway runs northeast, past the Perry Stokes Airport and crossing the Purgatoire River...
  
  
• U.S. Route 450
• U.S. Route 550
  U.S. Route 550
  U.S. Route 550 is a spur of U.S. Highway 50 that runs from Bernalillo, New Mexico to Montrose, Colorado in the western United States. The section from Silverton to Ouray is frequently called the Million Dollar Highway.- New Mexico :...
  
  
• U.S. Route 650