The Turbio River rises in a mountainous region of the Argentine

Argentina

Argentina , officially the Argentine Republic , is the second largest country in South America by land area, after Brazil. It is constituted as a federation of 23 provinces and an autonomous city, Buenos Aires...

 Andes

Andes

The Andes is the world's longest continental mountain range. It is a continual range of highlands along the western coast of South America. This range is about long, about to wide , and of an average height of about .Along its length, the Andes is split into several ranges, which are separated...

 and discharges to the Última Esperanza Sound

Última Esperanza Sound

Última Esperanza Sound is an inlet stretching from the mouth of Eberhard Fjord to the outskirts of Monte Balmaceda, within the Magallanes Basin. This inlet, known within Chile as Seno Última Esperanza, has the characteristics of a tidewater river and drains an extensive basin...

 in Chile

Chile

Chile ,officially the Republic of Chile , is a country in South America occupying a long, narrow coastal strip between the Andes mountains to the east and the Pacific Ocean to the west. It borders Peru to the north, Bolivia to the northeast, Argentina to the east, and the Drake Passage in the far...

. Río Turbio headwaters are in a part of the Andes where there is no central valley, or gap between the eastern and western ridges. Not far from its mouth to the northwest lies the Cueva del Milodon Natural Monument

Cueva del Milodón Natural Monument

Cueva del Milodón Natural Monument is a Natural Monument located in the Chilean Patagonia, northwest of Puerto Natales and north of Punta Arenas. The monument is situated along the flanks of the Cerro Benitez Mountains...

, where remains of the extinct Giant sloth were discovered along with evidence of habitation by early man c. 10,000 BC.