Tombusvirus
Encyclopedia
The genus
Tombusvirus are part of the family
Tombusviridae
and are members of group IV of the Baltimore classification of viruses. The genomes consist of positive sense single-stranded RNA
with a genome
size of 4800 nucleotide
s. The virions are non-enveloped with a diameter
of 30 nm and have an isometric nucleocapsid (icosahedral; T=3). These virions have a regular surface structure and are composed of 17% nucleic acid
.
This genera of viruses include the tomato bushy stunt virus
(hence the name).
The virus uses the cis-regulatory element
s, Tombus virus defective interfering (DI) RNA region 3
and Tombusvirus 5' UTR
to control expression of defective interfering RNAs and viral RNA replication.
Genus
In biology, a genus is a low-level taxonomic rank used in the biological classification of living and fossil organisms, which is an example of definition by genus and differentia...
Tombusvirus are part of the family
Family
In human context, a family is a group of people affiliated by consanguinity, affinity, or co-residence. In most societies it is the principal institution for the socialization of children...
Tombusviridae
Tombusviridae
Tombusviridae is a family of single-stranded positive sense RNA plant viruses. The name is derived from the type species of the Tombusvirus genus, Tomato bushy stunt virus...
and are members of group IV of the Baltimore classification of viruses. The genomes consist of positive sense single-stranded RNA
RNA
Ribonucleic acid , or RNA, is one of the three major macromolecules that are essential for all known forms of life....
with a genome
Genome
In modern molecular biology and genetics, the genome is the entirety of an organism's hereditary information. It is encoded either in DNA or, for many types of virus, in RNA. The genome includes both the genes and the non-coding sequences of the DNA/RNA....
size of 4800 nucleotide
Nucleotide
Nucleotides are molecules that, when joined together, make up the structural units of RNA and DNA. In addition, nucleotides participate in cellular signaling , and are incorporated into important cofactors of enzymatic reactions...
s. The virions are non-enveloped with a diameter
Diameter
In geometry, a diameter of a circle is any straight line segment that passes through the center of the circle and whose endpoints are on the circle. The diameters are the longest chords of the circle...
of 30 nm and have an isometric nucleocapsid (icosahedral; T=3). These virions have a regular surface structure and are composed of 17% nucleic acid
Nucleic acid
Nucleic acids are biological molecules essential for life, and include DNA and RNA . Together with proteins, nucleic acids make up the most important macromolecules; each is found in abundance in all living things, where they function in encoding, transmitting and expressing genetic information...
.
This genera of viruses include the tomato bushy stunt virus
Tomato bushy stunt virus
Tomato bushy stunt virus is a tombusvirus first reported in tomatoes in 1935. Depending upon the host, TBSV causes stunting of growth, leaf mottling, and deformed or absent fruit. The virus is transmitted manually through the use of contaminated cutting tools...
(hence the name).
The virus uses the cis-regulatory element
Cis-regulatory element
A cis-regulatory element or cis-element is a region of DNA or RNA that regulates the expression of genes located on that same molecule of DNA . This term is constructed from the Latin word cis, which means "on the same side as". These cis-regulatory elements are often binding sites for one or...
s, Tombus virus defective interfering (DI) RNA region 3
Tombus virus defective interfering (DI) RNA region 3
Tombus virus defective interfering RNA region 3 is an important cis-regulatory region identified in the 3' UTR of Tombusvirus defective interfering particles ....
and Tombusvirus 5' UTR
Tombusvirus 5' UTR
Tombusvirus 5' UTR is an important cis-regulatory region of the Tombus virus genome.Tomato bushy stunt virus is the prototype member of the Tombusviridae family. The genome of this virus is positive sense single stranded RNA. Replication occurs via a negative strand RNA intermediate...
to control expression of defective interfering RNAs and viral RNA replication.