Tomato bushy stunt virus
Encyclopedia
Tomato bushy stunt virus is a tombusvirus
Tombusvirus
The genus Tombusvirus are part of the family Tombusviridae and are members of group IV of the Baltimore classification of viruses. The genomes consist of positive sense single-stranded RNA with a genome size of 4800 nucleotides. The virions are non-enveloped with a diameter of 30 nm and have...

 first reported in tomatoes in 1935. Depending upon the host, TBSV causes stunting of growth, leaf mottling, and deformed or absent fruit. The virus is transmitted manually through the use of contaminated cutting tools. A wide variety of species are affected.

The virus is a spherical virus with a triangulation number of T = 3, hence has 180 subunits of capsid protein. In 1978, its structure was determined by x-ray crystallography by Stephen C. Harrison.

The genome of TBSV is a single-stranded positive-sense RNA of ~4800 nucleotides. The virus encodes 5 genes, to express a replicase composed of two proteins (P33 and P92), a capsid protein (CP) of 42 kilodaltons, as well as P19 and P22. The P22 protein is primarily associated with cell to cell movement. The P19 protein is a pathogenicity factor and also is a suppressor of gene silencing.
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