Textbook of Biochemistry
Encyclopedia
Textbook of Biochemistry, first published in 1928
1928 in literature
The year 1928 in literature involved some significant events and new books.-Events:*Ford Madox Ford publishes Last Post. It is the final book of a four-volume work titled Parade's End published between 1924 and 1928....

, is scientific textbook
Textbook
A textbook or coursebook is a manual of instruction in any branch of study. Textbooks are produced according to the demands of educational institutions...

 authored by Alexander Thomas Cameron
Alexander Thomas Cameron
Alexander Thomas Cameron was a British-born Canadian biochemist. He was best known as Professor of Biochemistry at the University of Manitoba, and as the author of numerous popular biochemistry textbooks, including Textbook of Biochemistry.-Biography:Alexander Thomas Cameron was born in 1882 in...

. The textbook became a standard of its field, and, by 1948, had gone through six editions, in addition to one Chinese and two Spanish editions.

Publication

Textbook of Biochemistry consists entirely of lecture manuscripts given by the author, Alexander Thomas Cameron, over several years. Cameron had lectured at the University of Manitoba
University of Manitoba
The University of Manitoba , in Winnipeg, Manitoba, Canada, is the largest university in the province of Manitoba. It is Manitoba's most comprehensive and only research-intensive post-secondary educational institution. It was founded in 1877, making it Western Canada’s first university. It placed...

 since 1909, but was never a fluent speaker. To compensate for this, he would write out his lectures in full. Cameron was encouraged by students and friends to submit his lecture manuscripts for publication. The textbook's first edition was published with a preface by Swale Vincent
Swale Vincent
Thomas Swale Vincent was a British physiologist.-Early years:Thomas Swale Vincent was the son of J. Vincent and Margaret Swale. He was educated at King Edward VI Grammar School in Birmingham, and subsequently studied at Mason College...

, Professor of Physiology at the University of London
University of London
-20th century:Shortly after 6 Burlington Gardens was vacated, the University went through a period of rapid expansion. Bedford College, Royal Holloway and the London School of Economics all joined in 1900, Regent's Park College, which had affiliated in 1841 became an official divinity school of the...

.

Structure

Textbook of Biochemistry is divided into the following chapters:
  • Introduction

Introduction to the concept of biochemistry, and a review of catalytic reactions and pH
PH
In chemistry, pH is a measure of the acidity or basicity of an aqueous solution. Pure water is said to be neutral, with a pH close to 7.0 at . Solutions with a pH less than 7 are said to be acidic and solutions with a pH greater than 7 are basic or alkaline...

.
  • Food-Stuffs, Their Derivatives and Related Substances.

Ideas regarding carbohydrates, lipids, and proteins.
  • The Chemistry of Digestion, the Circulation, and the Excreto.

The importance of bacterial
Bacteria
Bacteria are a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria have a wide range of shapes, ranging from spheres to rods and spirals...

 and chemical activity in organisms.
  • Intermediate Metabolism

The chemistry of tissues
Tissue (biology)
Tissue is a cellular organizational level intermediate between cells and a complete organism. A tissue is an ensemble of cells, not necessarily identical, but from the same origin, that together carry out a specific function. These are called tissues because of their identical functioning...

, intracellular synthesis, products of metabolism
Metabolism
Metabolism is the set of chemical reactions that happen in the cells of living organisms to sustain life. These processes allow organisms to grow and reproduce, maintain their structures, and respond to their environments. Metabolism is usually divided into two categories...

, and vitamins.
  • The Chemistry of Reproduction; The Chemical Controlling Agencies of the Organism.

The agents governing metabolic processes.
  • Quantitative Metabolism.
  • Addenda.

A review of the present status of immunological biochemistry
Immunology
Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. It deals with the physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders ; the...

, and applications of biochemistry in industry.

Reception

Treat B. Johnson, writing for the Journal of Chemical Education
Journal of Chemical Education
The Journal of Chemical Education is a monthly peer-reviewed academic journal available in both print and electronic versions. It is published by the Division of Chemical Education of the American Chemical Society and was established in 1924...

,
acknowledged the difficulty of concisely covering the rapidly growing field of biochemistry, but concluded that Cameron has "done quite well." He described Textbook of Biochemistry as "not a book that follows the ordinary logical procedure usually associated with such texts," and complements Cameron on a "dogmatic treatment which is really stimulating."

The British Medical Journal also gave a favourable review, writing that "the busy medical student will find this book a concise account of the facts with which he is expected to become familiar." However, it also observed that the book contains several statements that are "definitely not in agreement with the facts as at present known." The reviewer contradicts, for example, the book's assertions that urinal
Urine
Urine is a typically sterile liquid by-product of the body that is secreted by the kidneys through a process called urination and excreted through the urethra. Cellular metabolism generates numerous by-products, many rich in nitrogen, that require elimination from the bloodstream...

 ammonia
Ammonia
Ammonia is a compound of nitrogen and hydrogen with the formula . It is a colourless gas with a characteristic pungent odour. Ammonia contributes significantly to the nutritional needs of terrestrial organisms by serving as a precursor to food and fertilizers. Ammonia, either directly or...

 is formed in the kidneys from urea
Urea
Urea or carbamide is an organic compound with the chemical formula CO2. The molecule has two —NH2 groups joined by a carbonyl functional group....

, and that pepsin
Pepsin
Pepsin is an enzyme whose precursor form is released by the chief cells in the stomach and that degrades food proteins into peptides. It was discovered in 1836 by Theodor Schwann who also coined its name from the Greek word pepsis, meaning digestion...

 does not attack the CO-NH links in proteins
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...

.

Textbook of Biochemistry, being the first concise and authoritative work in its field, became a standard text. By 1948, it had gone through six editions, in addition to one Chinese and two Spanish editions.
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