TNFRSF10B
Encyclopedia
Tumor necrosis factor receptor superfamily, member 10b, official symbol TNFRSF10B, is a human gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

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As know as; DR5, CD262, KILLER, TRICK2, TRICKB, ZTNFR9, TRAILR2, TRICK2A, TRICK2B, TRAIL-R2, KILLER/DR5

Interactions

TNFRSF10B has been shown to interact
Protein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...

 with FADD
FADD
Fas-Associated protein with Death Domain is an adaptor molecule that bridges the Fas-receptor, and other death receptors, to caspase-8 through its death domain to form the death-inducing signaling complex during apoptosis. -Signalling:...

, TRAIL
TRAIL
In the field of cell biology, TNF-related apoptosis-inducing ligand , is a protein functioning as a ligand that induces the process of cell death called apoptosis. TRAIL has also been designated CD253 .- Gene :...

, Caspase 10
Caspase 10
Caspase-10 is an enzyme that, in humans, is encoded by the CASP10 gene.-Interactions:Caspase 10 has been shown to interact with FADD, CFLAR, Caspase 8, Fas receptor, RYBP, TNFRSF1A and TNFRSF10B.-External links:*...

 and Caspase 8
Caspase 8
Caspase 8 is a caspase protein, encoded by the CASP8 gene. It most likely acts upon caspase 3.CASP8 orthologs have been identified in numerous mammals for which complete genome data are available...

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Further reading

External links

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