POU2F1
Encyclopedia
POU domain, class 2, transcription factor 1 is a protein
that in humans is encoded by the POU2F1 gene
.
with SNAPC4
, Ku80, Glucocorticoid receptor
, Sp1 transcription factor, NPAT
, POU2AF1
, Host cell factor C1
, TATA binding protein
, RELA
, Nuclear receptor co-repressor 2
, EPRS
, Glyceraldehyde 3-phosphate dehydrogenase
, MNAT1
and Retinoid X receptor alpha
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the POU2F1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
POU2F1 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with SNAPC4
SNAPC4
snRNA-activating protein complex subunit 4 is a protein that in humans is encoded by the SNAPC4 gene.-Interactions:SNAPC4 has been shown to interact with SNAPC1, POU2F1 and SNAPC2.-Further reading:...
, Ku80, Glucocorticoid receptor
Glucocorticoid receptor
The glucocorticoid receptor also known as NR3C1 is the receptor to which cortisol and other glucocorticoids bind....
, Sp1 transcription factor, NPAT
NPAT (gene)
Protein NPAT is a protein that in humans is encoded by the NPAT gene.-Interactions:NPAT has been shown to interact with Glyceraldehyde 3-phosphate dehydrogenase and POU2F1.-Further reading:...
, POU2AF1
POU2AF1
POU domain class 2-associating factor 1 is a protein that in humans is encoded by the POU2AF1 gene.-Interactions:POU2AF1 has been shown to interact with POU2F1 and SIAH1.-Further reading:...
, Host cell factor C1
Host cell factor C1
Host cell factor is a protein that in humans is encoded by the HCFC1 gene.-Interactions:Host cell factor C1 has been shown to interact with HDAC1, Histone deacetylase 2, OGT, SIN3A, SUDS3, ZBTB17, Sp1 transcription factor, MLL, PPP1CA, POU2F1, PDCD2, WDR5, CREB3 and GABPA.-Further reading:...
, TATA binding protein
TATA Binding Protein
The TATA-binding protein is a general transcription factor that binds specifically to a DNA sequence called the TATA box. This DNA sequence is found about 35 base pairs upstream of the transcription start site in some eukaryotic gene promoters...
, RELA
RELA
Transcription factor p65 is a protein that in humans is encoded by the RELA gene.-Interactions:RELA has been shown to interact with NFKBIB, ETHE1, NFKBIE, RFC1, TRIB3, CREB binding protein, Neutrophil cytosolic factor 1, Glucocorticoid receptor, MTPN, BRCA1, C-Fos, POU2F1, BTRC, TATA-binding...
, Nuclear receptor co-repressor 2
Nuclear receptor co-repressor 2
The nuclear receptor co-repressor 2 is a transcriptional coregulatory protein that contains several nuclear receptor-interacting domains. In addition, NCOR2 appears to recruit histone deacetylases to DNA promoter regions. Hence NCOR2 assists nuclear receptors in the down regulation of target...
, EPRS
EPRS
Bifunctional aminoacyl-tRNA synthetase is an enzyme that in humans is encoded by the EPRS gene.- Gene :Alternative splicing has been observed for this gene, but the full-length nature and biological validity of the variant have not been determined....
, Glyceraldehyde 3-phosphate dehydrogenase
Glyceraldehyde 3-phosphate dehydrogenase
Glyceraldehyde 3-phosphate dehydrogenase is an enzyme of ~37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules...
, MNAT1
MNAT1
CDK-activating kinase assembly factor MAT1 is an enzyme that in humans is encoded by the MNAT1 gene.-Interactions:MNAT1 has been shown to interact with POU2F1, MTA1, Cyclin H, P53, Estrogen receptor alpha, MCM7 and Cyclin-dependent kinase 7....
and Retinoid X receptor alpha
Retinoid X receptor alpha
Retinoid X receptor alpha , also known as NR2B1 is a nuclear receptor that in humans is encoded by the RXRA gene.- Function :...
.