A nuclepore filter is a kind of filter

Filter (chemistry)

In chemistry and common usage, a filter is a device that is designed to physically block certain objects or substances while letting others through. Filters are often used to remove solid substances suspended in fluids, for example to remove air pollution, to make water drinkable, and to prepare...

 in which holes a few micrometre

Micrometre

A micrometer , is by definition 1×10-6 of a meter .In plain English, it means one-millionth of a meter . Its unit symbol in the International System of Units is μm...

s in size have been created in a plastic

Plastic

A plastic material is any of a wide range of synthetic or semi-synthetic organic solids used in the manufacture of industrial products. Plastics are typically polymers of high molecular mass, and may contain other substances to improve performance and/or reduce production costs...

 (e.g. polycarbonate

Polycarbonate

PolycarbonatePhysical PropertiesDensity 1.20–1.22 g/cm3Abbe number 34.0Refractive index 1.584–1.586FlammabilityV0-V2Limiting oxygen index25–27%Water absorption – Equilibrium0.16–0.35%Water absorption – over 24 hours0.1%...

) membrane

Artificial membrane

An artificial membrane, or synthetic membrane, is a synthetically created membrane which is usually intended for separation purposes in laboratory or in industry. Synthetic membranes have been successfully used for small and large-scale industrial processes since the middle of twentieth century. A...

. These filters are generally created by exposing the membrane to radiation

Radiation

In physics, radiation is a process in which energetic particles or energetic waves travel through a medium or space. There are two distinct types of radiation; ionizing and non-ionizing...

 that weakens the plastic and creates specific areas that can be removed by dousing the membrane in acid

Acid

An acid is a substance which reacts with a base. Commonly, acids can be identified as tasting sour, reacting with metals such as calcium, and bases like sodium carbonate. Aqueous acids have a pH of less than 7, where an acid of lower pH is typically stronger, and turn blue litmus paper red...

 (or other chemicals). The technique and patent was developed by P. Buford Price

P. Buford Price

Paul Buford Price, usually known as P. Buford Price, is a professor in the Graduate School at the University of California, Berkeley and a member of the National Academy of Sciences...

, et al. as an outgrowth of his cosmic ray

Cosmic ray

Cosmic rays are energetic charged subatomic particles, originating from outer space. They may produce secondary particles that penetrate the Earth's atmosphere and surface. The term ray is historical as cosmic rays were thought to be electromagnetic radiation...

 research. The technique allows for creating uniform holes of any desired diameter to allow even a virus to be filtered.

The most common use of nucleopore filters is in microbiology

Microbiology

Microbiology is the study of microorganisms, which are defined as any microscopic organism that comprises either a single cell , cell clusters or no cell at all . This includes eukaryotes, such as fungi and protists, and prokaryotes...

 where they are used to trap cell

Cell (biology)

The cell is the basic structural and functional unit of all known living organisms. It is the smallest unit of life that is classified as a living thing, and is often called the building block of life. The Alberts text discusses how the "cellular building blocks" move to shape developing embryos....

s while removing all other fluids and smaller particles.