Mandelate racemase
Encyclopedia
Mandelate racemase is a bacterial enzyme
which catalyzes the interconversion of the enantiomers of mandelate via an enol
intermediate.
It is a member of the enolase superfamily
of enzymes, along with muconate lactonizing enzyme
and enolase
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
which catalyzes the interconversion of the enantiomers of mandelate via an enol
Enol
Enols are alkenes with a hydroxyl group affixed to one of the carbon atoms composing the double bond. Alkenes with a hydroxyl group on both sides of the double bond are called enediols. Deprotonated anions of enols are called enolates...
intermediate.
It is a member of the enolase superfamily
Enolase superfamily
The reactions catalyzed by enzymes in the enolase superfamily share the core chemical step of an abstraction of a proton from a carbon adjacent to a carboxylic acid and a requirement of a divalent metal ion...
of enzymes, along with muconate lactonizing enzyme
Muconate lactonizing enzyme
Muconate lactonizing enzymes are involved in the breakdown of lignin-derived aromatics, catechol and protocatechuate, to citric acid cycle intermediates as a part of the β-ketoadipate pathway in soil microbes. Some bacterial species are also capable of dehalogenating chloroaromatic compounds by...
and enolase
Enolase
Enolase, also known as phosphopyruvate dehydratase, is a metalloenzyme responsible for the catalysis of the conversion of 2-phosphoglycerate to phosphoenolpyruvate , the ninth and penultimate step of glycolysis. Enolase belongs to the class Lyase. Enolase can also catalyze the reverse reaction,...
.