LG Life Sciences
Encyclopedia
LG
LG
LG may refer to:*LG Corp., a South Korean electronics and petrochemicals conglomerate*LG Electronics, an affiliate of the South Korean LG Group which produces electronic products* Lawrence Graham, a London headquartered firm of business lawyers...

 Life Sciences(LGLS)
spun off from LG Chem Investment as a full-fledged LG Group
LG Group
LG Corp. is the second-largest South Korean conglomerate company following Samsung, and it is headquartered in the LG Twin Towers in Yeouido-dong, Yeongdeungpo-gu, Seoul. LG produces electronics, chemicals, and telecommunications products and operates subsidiaries like LG Electronics, LG Display,...

 Affiliate in August 2002. LGLS began research in genetic engineering since 1981 and has developed and commercialized:

- interferon : Intermax-gamma(1989), Intermax-alpha(1992)

- hepatitis B vaccine : Euvax B(1992)

- human growth hormone : Eutropin(1993)

- quinolone antibiotic : Factive(2003)

- degenerative arthritis treatment : Hyruan Plus(2005)

- rhFSH (recombinant human follicle stimulating hormone) : Follitrope(2006)

- SR-hGH (Sustained Release-human Growth Hormone) : Declage(2007)

LG
LG
LG may refer to:*LG Corp., a South Korean electronics and petrochemicals conglomerate*LG Electronics, an affiliate of the South Korean LG Group which produces electronic products* Lawrence Graham, a London headquartered firm of business lawyers...

 Life Sciences has also been investing on new generation agrochemicals for nearly 20 years. Since then, LGLS has developed:

- new herbicide for rice : Pyancor(1997)

- fungicide for use in horticulture : Guardian(1999)

- new herbicide for both pre- and post-emergence rice : Fluxo(2004)

Business Areas

1. Pharmaceuticals

LG
LG
LG may refer to:*LG Corp., a South Korean electronics and petrochemicals conglomerate*LG Electronics, an affiliate of the South Korean LG Group which produces electronic products* Lawrence Graham, a London headquartered firm of business lawyers...

 Life Sciences(LGLS) has an extensive sales and marketing network spanning over 75 countries with LGLS technology based products. Among these products, Factive is a representative Korean drug which is yet only FDA approved novel drug in Korea. Factive is a dual targeting fluroquinolone antibiotic selling over 15 countries worldwide.
Also, LGLS is a major hepatitis B vaccine supplier of UN agencies and has exported to more than 75 countries in the world. LGLS hepatitis B vaccine, Euvax B takes up over 50% of UNICEF supply.
In 2007, an additional success to domestic marketing, Hyruan Plus, an osteoarthritis treatment has achieved CE marking and now is marketed over 20 countries including Europe. Hyruan Plus is highly purified hyaluronic acid, processed by microbial fermentation which ensures to be BSE-free. Showing LGLS’ advanced bioengineering technology, LGLS developed one of very few biosimilar recombinant human erythropoietin and follitropin that are registered and marketed over 15 countries. In addition to Euvax B, and Factive, LGLS has many infertility treatments, ophthalmic surgical interventions, diagnostics drugs, animal drug, and pharmaceutical drug intermediates that are exported all over the world.

2. Specialty Chemicals

For nearly 20 years, LG
LG
LG may refer to:*LG Corp., a South Korean electronics and petrochemicals conglomerate*LG Electronics, an affiliate of the South Korean LG Group which produces electronic products* Lawrence Graham, a London headquartered firm of business lawyers...

 Life Sciences has been developing and marketing new generation agrochemicals. The company’s earlier product line consisted of pyrethroid insecticides, including Cypermethrin
Cypermethrin
Cypermethrin is a synthetic pyrethroid used as an insecticide in large-scale commercial agricultural applications as well as in consumer products for domestic purposes. It behaves as a fast-acting neurotoxin in insects. It is easily degraded on soil and plants but can be effective for weeks when...

, Deltamethrin
Deltamethrin
Deltamethrin is a pyrethroid ester insecticide.-Usage:Deltamethrin products are among the most popular and widely used insecticides in the world and have become very popular with pest control operators and individuals in the United States in the past five years. This material is a member of one of...

, and Lambdacyhalothrin. LGLS produced these insecticides because manufacturing such products was a technical challenge in the early to mid 1980s. As soon as pyrethroid chemistry ceased to be a challenge, the company moved on to a new technical challenge. LGLS now has three new molecules(Pyanchor, Guardian, Fluxo) being developed globally.
In the past two years, the structure of LGLS’s crop protection business has changed significantly, from technology to business integration, to achieve sustainable and healthy growth. The company emphasizes strong global partnerships with multinationals regarding its proprietary molecules, while strengthening its domestic operations through strategic ties with local and independent sales networks.
Since 2000, LGLS has been expanding into the generic product sector in the U.S., the world’s largest agrochemical market. In addition to Permethrin
Permethrin
Permethrin is a common synthetic chemical, widely used as an insecticide, acaricide, and insect repellent. It belongs to the family of synthetic chemicals called pyrethroids and functions as a neurotoxin, affecting neuron membranes by prolonging sodium channel activation. It is not known to...

, LGLS registered three of its generic products with the EPA in 2006, Metalaxyl
Metalaxyl
Metalaxyl is a phenylamide fungicide with systemic function. Its chemical name is methyl N--N--DL-alaninate. It can be used to control Pythium in a number of vegetable crops, and Phytophthora in peas....

, Lambda-Cyhalothrin, and Esfenvalerate. LGLS plans to continue expanding its U.S. business by introducing additional products.

3. Diagnostics

LG
LG
LG may refer to:*LG Corp., a South Korean electronics and petrochemicals conglomerate*LG Electronics, an affiliate of the South Korean LG Group which produces electronic products* Lawrence Graham, a London headquartered firm of business lawyers...

 Life Sciences has invested and researched constantly over the past two decades in diagnostics areas and has developed in-vitro diagnostics for Hepatitis C(first in Korea), Malaria antibodies(first in the world), HIV antigens and antibodies, Syphillis and Hepatitis B virus.
LGLS’s goal in diagnostics R&D is to raise the competitiveness of current products and to cultivate a steady stream of strategic products for the future. To this end, core competencies are being strengthened and its efforts focus on new product development. The trend in diagnostic medicine technology today is to generate value by incorporating information, nanotechnologies and biotechnologies. LGLS is building upon its world-class technology in infections diseases and accelerating R&D research to secure a technological edge in ELISA
ELISA
Enzyme-linked immunosorbent assay , is a popular format of a "wet-lab" type analytic biochemistry assay that uses one sub-type of heterogeneous, solid-phase enzyme immunoassay to detect the presence of a substance in a liquid sample."Wet lab" analytic biochemistry assays involves detection of an...

, real-time PCR and several types of biochips.

Major Products

1. Pharmaceuticals - Biologics and Vaccines

- Eutropin Inj. : Infant dwarfism by lack of growth hormone and Turner syndrome, adult growth hormone deficiency

- Hyruan Plus Inj. : Degenerative arthritis

- Euvax B Inj. : Immunization against infection caused by hepatitis B virus

- Espogen Inj. : Anemia in patients with chronic renal failure

- Intermax Alpha Inj. : Chronic hepatitis C, CML etc.

- Follitrope Inj. : Ovulation induction in assisted reproduction program

- Intermax Gamma Inj. : Rheumatic arthritis and myeloid leukemia

2. Pharmaceuticals - Small Molecules

- Zanidip Tab. : Essential hypertension

- Calvan Tab. : Hypertension

- IVF-M Inj., IVF-C Inj., Follimon Inj. : Ovulation induction in assisted reproduction program

- Factive Chronic bronchitis, pneumonia, and sinusitis

3. Specialty Chemicals

- Pyanchor(Pyribenzoxim[PBX]) : Paddy fields(barnyard grass, spiderwort)

- Veteran(Imidacloprid[ICP]) : Orcharding and horticulture(aphids, moths)

- Guardian(Ethaboxam[EBX]) : Orcharding and horticulture(epidemics, downy mildews)

- Fluxo(Flucetosulfuron[FTS]) : Paddy fields(broad-spectrum herbicide)

4. Diagnostics

- AdvanSure HPV Screening real-time PCR : For screening HPV virus in vaginal swap

- AdavanSure TB/NTM real-time PCR : Detecting M.tb complex and NTM(non-tubercle Mycobacteria) respectively

- AdvanSure Mycobacteria Genotyping Chip : Identifying 28 species of Mycobacteria by Hybridizing with PCR product targeted ITS (Internal Transcribed Spacer) region

External links

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