Jacques-Joseph Grancher
Encyclopedia
Jacques-Joseph Grancher was a French pediatrician who was born in Felletin
. In 1865 he earned his medical degree, and afterwards was director of a pathological
anatomy
laboratory in Clamart
(1868–1878). From 1885 until his death in 1907 he was director of Hôpital des Enfants Malades in Paris
. He was also a member of the Board of Directors of the Pasteur Institute
.
Grancher is remembered for his research involving tuberculosis
. He was a pioneer concerning the creation of safeguards in the prevention of childhood tuberculosis, and was an advocate of isolation and antisepsis in the fight against the disease. In 1897 with Jules Comby
(1853–1947) and Antoine Marfan
(1858–1942) he published Traité des maladies de l’enfance (Treatise of the Diseases of Childhood).
In 1885 Grancher and Alfred Vulpian
(1826–1887) were instrumental in convincing Louis Pasteur
(1822–1895) to perform the first successful vaccination
against rabies
on Joseph Meister
, a 9-year-old boy who had been mauled by a rabid dog. In 1887 at the request of Pasteur, Grancher defended the rabies vaccination to the Académie de Médecine, citing its successful survival rate.
Felletin
Felletin is a commune in the Creuse department in the Limousin region in central France.-Geography:An area of lakes and streams, forestry and farming comprising a small town and several villages and hamlets situated by the banks of the Creuse River just south of Aubusson at the junction of the...
. In 1865 he earned his medical degree, and afterwards was director of a pathological
Pathology
Pathology is the precise study and diagnosis of disease. The word pathology is from Ancient Greek , pathos, "feeling, suffering"; and , -logia, "the study of". Pathologization, to pathologize, refers to the process of defining a condition or behavior as pathological, e.g. pathological gambling....
anatomy
Anatomy
Anatomy is a branch of biology and medicine that is the consideration of the structure of living things. It is a general term that includes human anatomy, animal anatomy , and plant anatomy...
laboratory in Clamart
Clamart
Clamart is a commune in the southwestern suburbs of Paris, France. It is located from the center of Paris.The town is divided into two parts, separated by a forest: bas Clamart, the historical centre, and petit Clamart with urbanization developed in the 1960s replacing pea fields. The canton of...
(1868–1878). From 1885 until his death in 1907 he was director of Hôpital des Enfants Malades in Paris
Paris
Paris is the capital and largest city in France, situated on the river Seine, in northern France, at the heart of the Île-de-France region...
. He was also a member of the Board of Directors of the Pasteur Institute
Pasteur Institute
The Pasteur Institute is a French non-profit private foundation dedicated to the study of biology, micro-organisms, diseases, and vaccines. It is named after Louis Pasteur, who made some of the greatest breakthroughs in modern medicine at the time, including pasteurization and vaccines for anthrax...
.
Grancher is remembered for his research involving tuberculosis
Tuberculosis
Tuberculosis, MTB, or TB is a common, and in many cases lethal, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. Tuberculosis usually attacks the lungs but can also affect other parts of the body...
. He was a pioneer concerning the creation of safeguards in the prevention of childhood tuberculosis, and was an advocate of isolation and antisepsis in the fight against the disease. In 1897 with Jules Comby
Jules Comby
Jules Comby was a French pediatrician. With Antoine Marfan and Jacques-Joseph Grancher , he published the influential Traité des maladies de l’enfance...
(1853–1947) and Antoine Marfan
Antoine Marfan
Antoine Bernard-Jean Marfan was a French pediatrician. He was born in Castelnaudary to Antoine Prosper Marfan and Adélaïde Thuries....
(1858–1942) he published Traité des maladies de l’enfance (Treatise of the Diseases of Childhood).
In 1885 Grancher and Alfred Vulpian
Alfred Vulpian
Edmé Félix Alfred Vulpian was a French physician and neurologist. He was the co-discoverer of Vulpian-Bernard spinal muscular atrophy and the Vulpian-Heidenhain-Sherrington phenomenon....
(1826–1887) were instrumental in convincing Louis Pasteur
Louis Pasteur
Louis Pasteur was a French chemist and microbiologist born in Dole. He is remembered for his remarkable breakthroughs in the causes and preventions of diseases. His discoveries reduced mortality from puerperal fever, and he created the first vaccine for rabies and anthrax. His experiments...
(1822–1895) to perform the first successful vaccination
Vaccination
Vaccination is the administration of antigenic material to stimulate the immune system of an individual to develop adaptive immunity to a disease. Vaccines can prevent or ameliorate the effects of infection by many pathogens...
against rabies
Rabies
Rabies is a viral disease that causes acute encephalitis in warm-blooded animals. It is zoonotic , most commonly by a bite from an infected animal. For a human, rabies is almost invariably fatal if post-exposure prophylaxis is not administered prior to the onset of severe symptoms...
on Joseph Meister
Joseph Meister
Joseph Meister was the first person to be inoculated against rabies by Louis Pasteur, and the first person to be successfully treated for the infection....
, a 9-year-old boy who had been mauled by a rabid dog. In 1887 at the request of Pasteur, Grancher defended the rabies vaccination to the Académie de Médecine, citing its successful survival rate.
External links
- Portail Institut Pasteur (chronological biography)