Interleukin-12 receptor
Encyclopedia
Interleukin 12 receptor is a type I cytokine receptor
, binding interleukin 12
. It consists of beta 1
and beta 2 subunit
s.
Type I cytokine receptor
Type I cytokine receptors are transmembrane receptors expressed on the surface of cells that recognize and respond to cytokines with four α-helical strands. These receptors are also known under the name hemopoietin receptors, and share a common amino acid motif in the extracellular portion...
, binding interleukin 12
Interleukin 12
Interleukin 12 is an interleukin that is naturally produced by dendritic cells, macrophages and human B-lymphoblastoid cells in response to antigenic stimulation.-Gene and structure:...
. It consists of beta 1
Interleukin 12 receptor, beta 1 subunit
Interleukin 12 receptor, beta 1 is a subunit of the interleukin 12 receptor. IL12RB1, is its human gene. IL12RB1 is also known as CD212 ....
and beta 2 subunit
Interleukin 12 receptor, beta 2 subunit
Interleukin 12 receptor, beta 2 subunit is a subunit of the interleukin 12 receptor. IL12RB2 is its human gene. IL12RB2 orthologs have been identified in all mammals for which complete genome data are available.-Interactions:...
s.