Human umbilical vein graft
A human umbilical vein graft (HUVG) is a specially prepared human
Humans are the only living species in the Homo genus...

 umbilical vein
Umbilical vein
The umbilical vein is a vein present during fetal development that carries oxygenated blood from the placenta to the growing fetus.The blood pressure inside the umbilical vein is approximately 20 mmHg.-Development:...

 that is used as a vascular graft
Medical grafting
Grafting refers to a surgical procedure to move tissue from one site to another on the body, or from another person, without bringing its own blood supply with it. Instead, a new blood supply grows in after it is placed. A similar technique where tissue is transferred with the blood supply intact...

. HUVGs have found use in arteriovenous fistulae (for patients with ESRD undergoing hemodialysis
In medicine, hemodialysis is a method for removing waste products such as creatinine and urea, as well as free water from the blood when the kidneys are in renal failure. Hemodialysis is one of three renal replacement therapies .Hemodialysis can be an outpatient or inpatient therapy...

), as an interposition graft between the subclavian artery
Subclavian artery
In human anatomy, the subclavian arteries are two major arteries of the upper thorax , below the clavicle . They receive blood from the top of the aorta...

 and pulmonary artery
Pulmonary artery
The pulmonary arteries carry deoxygenated blood from the heart to the lungs. They are the only arteries that carry deoxygenated blood....

 (in the Blalock-Taussig shunt
Blalock-Taussig shunt
The Blalock–Taussig shunt is a surgical procedure to give palliation to cyanotic heart defects which are common causes of blue baby syndrome...

 procedure), and for peripheral bypass graft surgery vascular bypass, when the great saphenous vein
Great saphenous vein
The great saphenous vein , also long saphenous vein, is the large superficial vein of the leg and thigh.The terms "safaina" and "el safin" have both been claimed as the origin for the word "saphenous."-Path:The GSV originates from where the dorsal vein of the first digit...

 (the preferred conduit) is unavailable or unusable.

HUVGs for peripheral bypass grafts are second only to the saphenous vein for long-term patency. However, they do have some tendency to form aneurysm
An aneurysm or aneurism is a localized, blood-filled balloon-like bulge in the wall of a blood vessel. Aneurysms can commonly occur in arteries at the base of the brain and an aortic aneurysm occurs in the main artery carrying blood from the left ventricle of the heart...

s and require more delicate handling than synthetic graft material from PETE
Pete is a diminutive from Peter. It may refer to:-Athletics:* The Pete, Petersen Events Center, athletics complex and basketball arena on the campus of the University of Pittsburgh* Pete the Penguin, mascot of Youngstown State University...

 (Dacron) or PTFE.

External links

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