HLA-B70
Encyclopedia
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| HLA-B (alpha)-β2MG with bound peptide | ||
| Alleles | *1503, *1509, *1510, *1518, *1529, *1537 | |
| Structure (See HLA-B HLA-B HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex... ) |
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| Shared data | ||
| Locus Locus (genetics) In the fields of genetics and genetic computation, a locus is the specific location of a gene or DNA sequence on a chromosome. A variant of the DNA sequence at a given locus is called an allele. The ordered list of loci known for a particular genome is called a genetic map... |
chr.6 Chromosome 6 (human) Chromosome 6 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 6 spans more than 170 million base pairs and represents between 5.5 and 6% of the total DNA in cells... 6p21.31 |
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HLA-B70 (B70) is an HLA
Human leukocyte antigen
The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...
-B
HLA-B
HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex...
serotype
Serotype
Serotype or serovar refers to distinct variations within a subspecies of bacteria or viruses. These microorganisms, viruses, or cells are classified together based on their cell surface antigens...
. The serotype identifies certain B*15 gene-allele protein products of HLA-B.
B70 is one of many split antigens of the broad antigen, B15
HLA-B15
HLA-B15 is an HLA-B serotype. The serotype identifies the B*15 gene-allele protein products of HLA-B.B15 is a broad antigen can be subdivided into several split antigens that are often used in characterization. These are B62, B63, B70, B71, B72, B75, B76, B77...
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Serotype
| B*15 | B15 | B62 | B63 | B70 | B71 | B72 | B75 | B76 | B77 | Sample |
| allele | % | % | % | % | % | % | % | % | % | size (N) |
| 1 | 61 | 10 | 2569 | |||||||
| 53 | 65 | |||||||||
| 1 | 49 | 2 | 2 | 1 | 1204 | |||||
| 51 | 3 | 552 | ||||||||
| 19 | 21 | |||||||||
| 30 | 34 | |||||||||
| Alleles link-out to IMGT/HLA Human leukocyte antigen The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and... Databease at EBI European Bioinformatics Institute The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory... |
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Alleles
| freq | ||
| ref. | Population | (%) |
| Burkina Faso Rimaibe | 13.8 | |
| Guinea Bissau | 10.8 | |
| Cameroon Pygmy Baka | 10.0 | |
| South Africian Natal Zulu | 9.5 | |
| Kenya Luo | 8.9 | |
| Ivory Coast Akan Adiopodoume | 8.0 | |
| Kenya Nandi | 7.9 | |
| Cameroon Sawa | 7.7 | |
| Zimbabwe Harare Shona | 7.7 | |
| USA African America | 7.3 | |
| Burkina Faso Fulani | 7.1 | |
| Mali Bandiagara | 6.9 | |
| Senegal Niokholo Mandenka | 6.9 | |
| Cape Verde SE Islands | 6.5 | |
| Kenya | 6.3 | |
| Uganda Kampala | 6.2 | |
| Sudanese | 6.0 | |
| Zambia Lusaka | 5.7 | |
| Cameroon Yaounde | 4.9 | |
| Cape Verde NW Islands | 4.8 | |
| Oman | 4.7 | |
| Cameroon Bamileke | 4.5 | |
| Tunisia Tunis | 4.5 | |
| Cameroon Beti | 3.7 | |
| Brazil Belo Horizonte | 3.2 | |
| Azores Terceira Island | 2.4 | |
| Madeira | 2.2 | |
| Saudi Arabia Guraiat and Hail | 2.0 | |
| Tunisia | 2.0 | |
| United Arab Emerates | 1.5 | |
| Brazil | 1.4 | |
| Cuban White | 1.4 | |
| Morocco Nador Metalsa | 1.4 | |
| Mexico Mestizos | 1.2 | |
| Italy Bergamo | 1.1 | |
| Portugal North | 1.1 | |
| American Samoa | 1.0 | |
| Iran Baloch | 1.0 | |
| Mexico Guadalajara Mestizos (2) | 1.0 | |
| Azores Central Islands | 0.9 | |
| Israel Ashk. and Non-Ashk. Jews | 0.9 | |
| Taiwan Hakka | 0.9 | |
| Croatia | 0.7 |
| freq | ||
| ref. | Population | (%) |
| Burkina Faso Fulani | 4.1 | |
| India West Coast Parsis | 3.0 | |
| Spain Eastern Andalusia Gipsy | 3.0 | |
| Mexico Mestizos | 2.4 | |
| Italy South Campania | 1.2 | |
| Burkina Faso Rimaibe | 1.1 | |
| China Inner Mongolia | 1.0 | |
| Mali Bandiagara | 0.7 | |
| Czech Republic | 0.5 |
| freq | ||
| ref. | Population | (%) |
| South Africian Natal Zulu | 8.5 | |
| Zimbabwe Harare Shona | 8.4 | |
| Ivory Coast Akan Adiopodoume | 5.7 | |
| Kenya | 5.2 | |
| Zambia Lusaka | 4.6 | |
| Cameroon Sawa | 3.8 | |
| Guinea Bissau | 3.8 | |
| Kenya Luo | 3.6 | |
| Senegal Niokholo Mandenka | 3.2 | |
| Cameroon Beti | 2.8 | |
| USA African Americans (3) | 2.7 | |
| Uganda Kampala | 2.5 | |
| Mexico Mestizos | 2.4 | |
| Mali Bandiagara | 2.2 | |
| Kenya Nandi | 1.7 | |
| Brazil Belo Horizonte | 1.6 | |
| Cameroon Bamileke | 1.3 | |
| Cuban Mulatto | 1.2 | |
| Cameroon Yaounde | 1.1 | |
| Iran Baloch | 1.0 | |
| Sudanese | 1.0 | |
| Tunisia | 1.0 | |
| Brazil Terena | 0.9 | |
| Cape Verde NW Islands | 0.8 | |
| United Arab Emerates | 0.8 | |
| USA North American Natives | 0.8 | |
| Guadalajara Mestizos (2) | 0.5 |
| freq | ||
| ref. | Population | (%) |
| South Africa Natal Tamil | 4.1 | |
| Autonomous Tibetans | 3.8 | |
| India Mumbai Marathas | 3.7 | |
| China North Han | 2.9 | |
| USA Hawaii Okinawa | 2.9 | |
| China Guangzhou Han | 2.4 | |
| India Andhra Pradesh Golla | 2.4 | |
| China Beijing | 2.3 | |
| Taiwan Hakka | 1.8 | |
| Japan | 1.7 | |
| India North Delhi | 1.6 | |
| China Inner Mongolia | 1.5 | |
| China Qinghai Hui | 1.4 | |
| Czech Republic | 1.4 | |
| China Yunnan Nu | 1.3 | |
| Shijiazhuang Tianjian Han | 1.1 | |
| Ivory Coast Akan Adiopodoume | 1.1 | |
| Senegal Niokholo Mandenka | 1.1 | |
| Zambia Lusaka | 1.1 | |
| Portugal Centre | 1.0 | |
| Singapore Javanese Indonesians | 1.0 | |
| Thailand (3) | 1.0 | |
| South Korea (3) | 0.9 | |
| Cape Verde Islands | 0.8 | |
| France South East | 0.8 | |
| Guinea Bissau | 0.8 | |
| China South Han | 0.7 | |
| China Yunnan Lisu | 0.7 | |
| Russia Tuva (2) | 0.6 | |
| Singapore Chinese Han | 0.6 | |
| Spain Eastern Andalusia | 0.6 |