HLA-B62
Encyclopedia
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| HLA-B62 with bound peptide | ||
| Alleles | *1501, *1504, *1507, *1525 | |
| Structure (See HLA-B HLA-B HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex... ) |
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| Shared data | ||
| Locus Locus (genetics) In the fields of genetics and genetic computation, a locus is the specific location of a gene or DNA sequence on a chromosome. A variant of the DNA sequence at a given locus is called an allele. The ordered list of loci known for a particular genome is called a genetic map... |
chr.6 Chromosome 6 (human) Chromosome 6 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 6 spans more than 170 million base pairs and represents between 5.5 and 6% of the total DNA in cells... 6p21.31 |
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HLA-B62 (B62) is an HLA
Human leukocyte antigen
The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...
-B
HLA-B
HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex...
serotype
Serotype
Serotype or serovar refers to distinct variations within a subspecies of bacteria or viruses. These microorganisms, viruses, or cells are classified together based on their cell surface antigens...
. The serotype identifies certain B*15 gene-allele protein products of HLA-B.
B62 is largest of many split antigens of the broad antigen, B15
HLA-B15
HLA-B15 is an HLA-B serotype. The serotype identifies the B*15 gene-allele protein products of HLA-B.B15 is a broad antigen can be subdivided into several split antigens that are often used in characterization. These are B62, B63, B70, B71, B72, B75, B76, B77...
. B62 best identifies the B*1501, B*1504, B*1507, and B*1525 allele products.
Serotype
| B*15 | B15 | B62 | B63 | B70 | B71 | B72 | B75 | B76 | B77 | Sample |
| allele | % | % | % | % | % | % | % | % | % | size (N) |
| 2 | 96 | 1906 | ||||||||
| 10 | 69 | 29 | ||||||||
| 18 | 64 | 22 | ||||||||
| 40 | 20 | 11 | 10 | |||||||
| 79 | 101 | |||||||||
| 20 | 18 | 45 | ||||||||
| 15 | 27 | 21 | 68 | |||||||
| 17 | 18 | 8 | 12 | |||||||
| 13 | 49 | 28 | 138 | |||||||
| 100 | 5 | |||||||||
| 44 | 54 | |||||||||
| 7 | 74 | 8 | 116 | |||||||
| 7 | 76 | 76 | ||||||||
| 14 | 57 | 14 | 7 | |||||||
| 17 | 64 | 98 | ||||||||
| 50 | 12 | |||||||||
| 79 | 34 | |||||||||
| Allele | B15 | B62 | B63 | B70 | B71 | B72 | B75 | B76 | B77 | N |
| Alleles link-out to IMGT/HLA Human leukocyte antigen The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and... Databease at EBI European Bioinformatics Institute The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory... |
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Alleles
| freq | ||
| ref. | Population | (%) |
| Japan Ainu Hokkaido | 29.0 | |
| Chihuahuan Tarahumara | 14.8 | |
| Autonomous Tibetans | 12.3 | |
| South Korea ( 3) | 10.5 | |
| Japan Central | 8.7 | |
| Japan pop3 | 7.5 | |
| USA North American Natives | 7.2 | |
| South Dakota Lakota Sioux | 7.1 | |
| Shijiazhuang Tianjian Han | 7.0 | |
| China Qinghai Hui | 6.8 | |
| Croatia | 6.7 | |
| Japan pop5 | 6.5 | |
| Portugal Centre | 6.0 | |
| Taiwan Rukai | 6.0 | |
| USA Alaska Yupik Natives | 5.8 | |
| Australia New South Wales | 5.6 | |
| USA European Americans (2) | 5.6 | |
| France South East | 5.5 | |
| China Beijing | 5.3 | |
| Czech Republic | 4.7 | |
| Ireland South | 4.6 | |
| Mexico Sonora Seri | 4.5 | |
| China Inner Mongolia | 4.4 | |
| Russia Tuva (2) | 4.2 | |
| Singapore Chinese | 4.0 | |
| Taiwan Paiwan | 3.9 | |
| China North Han | 3.8 | |
| Georgia Svaneti Svans | 3.8 | |
| Ireland Northern | 3.8 | |
| Italy North Pavia | 3.7 | |
| Mexico Mestizos | 3.7 | |
| Azores Central Islands | 3.6 | |
| Madeira | 3.5 | |
| Taiwan Minnan pop 1 | 3.4 | |
| Azores Terceira Island | 3.1 | |
| Taiwan Siraya | 2.9 | |
| USA Hispanic | 2.8 | |
| Taiwan Hakka | 2.7 | |
| Taiwan Pazeh | 2.7 | |
| China Yunnan Nu | 2.6 | |
| Uganda Kampala | 2.5 | |
| Argentina Toba Rosario | 2.3 | |
| Romanian | 2.3 | |
| Hong Kong Chinese | 2.2 | |
| India North Hindus | 1.9 | |
| New Caledonia | 1.9 | |
| Italy South Campania | 1.8 | |
| Taiwan Thao | 1.7 | |
| India North Delhi | 1.6 | |
| China Guangzhou | 1.5 | |
| China Guangxi Maonan | 1.4 | |
| China Yunnan Lisu | 1.4 | |
| Thailand | 1.4 | |
| PNG New Britain Rabaul | 1.3 | |
| Brazil Belo Horizonte | 1.1 | |
| Cameroon Yaounde | 1.1 | |
| Portugal North | 1.1 | |
| United Arab Emerates | 1.1 | |
| Thailand pop3 | 1.0 | |
| USA African America | 1.0 | |
| USA African Americans | 1.0 | |
| Indig. Australian Yuendumu | 0.8 | |
| PNG Wanigela | 0.8 | |
| Mexico Zaptotec Oaxaca | 0.7 | |
| Spain Eastern Andalusia | 0.6 | |
| South Africian Natal Zulu | 0.5 | |
| Spain E. Andalusia Gipsy | 0.5 | |
| Sudanese | 0.5 | |
| Taiwan Bunun | 0.5 |
| freq | ||
| ref. | Population | (%) |
| Mexico Mestizos | 2.4 | |
| Mex. Guadalajara Mestizos (2) | 1.9 | |
| Argentina Toba Rosario | 1.2 | |
| China Guangdong Meizhou Han | 1.0 | |
| China North Han | 1.0 | |
| Cape Verde NW Islands | 0.8 | |
| USA South Texas Hispanics | 0.8 | |
| USA San Antonio Caucasians | 0.6 | |
| USA Hispanic | 0.4 | |
| USA Asian | 0.3 | |
| USA North American Natives | 0.3 | |
| USA African America | 0.2 | |
| Hong Kong Chinese | 0.1 |
| freq | ||
| ref. | Population | (%) |
| Taiwan Tao | 40.0 | |
| Taiwan Thao | 11.7 | |
| Taiwan Pazeh | 10.9 | |
| China Yunnan Lisu | 8.7 | |
| China Yunnan Nu | 8.3 | |
| PNG West Schrader Ranges | 8.2 | |
| Indig. Australian Groote Eylandt | 8.0 | |
| Taiwan Puyuma | 7.0 | |
| Taiwan Rukai | 7.0 | |
| Taiwan Bunun | 6.4 | |
| Indig. Australian Yuendumu | 5.7 | |
| Taiwan Siraya | 4.9 | |
| Taiwan Tsou | 4.9 | |
| Philippines Ivatan | 3.0 | |
| Taiwan Atayal | 2.8 | |
| Taiwan Ami | 2.6 | |
| Thailand | 2.5 | |
| China Guangzhou | 2.0 | |
| Thailand pop3 | 2.0 | |
| Hong Kong Chinese | 1.9 | |
| PNG Wanigela | 1.5 | |
| PNG Wosera | 1.5 | |
| Singapore Thai | 1.5 | |
| India Andhra Pradesh Golla | 1.4 | |
| PNG Eastern Highlands Goroka | 1.4 | |
| China South Han | 1.1 | |
| China Inner Mongolia | 1.0 | |
| India North Hindus | 1.0 |
| freq | ||
| ref. | Population | (%) |
| Argentina Toba Rosario | 8.1 | |
| New Mexico Canoncito Navajo | 3.7 | |
| Brazil Terena | 2.6 | |
| USA North American Natives | 0.8 | |
| Japan Central | 0.7 | |
| South Korea pop 3 | 0.6 | |
| Japan pop3 | 0.4 | |
| USA Asian | 0.4 | |
| Shijiazhuang Tianjian Han | 0.3 | |
| USA Caucasian pop2 | 0.2 | |
| Hong Kong Chinese | 0.1 | |
| Ireland Northern | 0.1 |