HLA-B42
Encyclopedia
| Alleles | B*4201 B*4202 | |
| Structure (See HLA-B HLA-B HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex... ) |
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| Symbol(s) Human Genome Organisation The Human Genome Organisation is an organization involved in the Human Genome Project, a project about mapping the human genome. HUGO was established in 1989 as an international organization, primarily to foster collaboration between genome scientists around the world... |
HLA-B | |
| EBI-HLA European Bioinformatics Institute The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory... |
B*4201 | |
| EBI-HLA European Bioinformatics Institute The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory... |
B*4202 | |
| Locus Locus (genetics) In the fields of genetics and genetic computation, a locus is the specific location of a gene or DNA sequence on a chromosome. A variant of the DNA sequence at a given locus is called an allele. The ordered list of loci known for a particular genome is called a genetic map... |
chr.6 Chromosome 6 (human) Chromosome 6 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 6 spans more than 170 million base pairs and represents between 5.5 and 6% of the total DNA in cells... 6p21.31 |
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HLA-B42 (B42) is an HLA
Human leukocyte antigen
The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...
-B
HLA-B
HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex...
serotype
Serotype
Serotype or serovar refers to distinct variations within a subspecies of bacteria or viruses. These microorganisms, viruses, or cells are classified together based on their cell surface antigens...
. The serotype identifies the HLA-B*4201 and *4202 gene products. HLA-B*4201 is common in Central Africa. (For terminology help see: HLA-serotype tutorial)
Serotype
| B*42 | B42 | other | Sample |
| allele | % | % | size (N) |
| 4201 | 93 | 2 | 1015 |
| 4202 | 95 | 80 |
Serological typing for B*4201 and B*4202 is relatively efficient.
B*4201 allele frequencies
| freq | ||
| ref. | Population | (%) |
| Zambia Lusaka | 14.8 | |
| Mali Bandiagara | 13.8 | |
| Burkina Faso Mossi | 13.2 | |
| South Africian Natal Zulu | 12.0 | |
| Burkina Faso Rimaibe | 9.6 | |
| South Africa Tswana | 8.5 | |
| Kenya Luo | 7.7 | |
| Kenya | 7.3 | |
| Kenya Nandi | 6.9 | |
| Zimbabwe Harare Shona | 6.9 | |
| Saudi Arabia | 5.6 | |
| Cameroon Yaounde | 4.9 | |
| Cameroon Beti | 4.0 | |
| Cameroon Bamileke | 3.9 | |
| Cameroon Sawa | 3.8 | |
| Ivory Coast Akan Adiopodoume | 3.4 | |
| Israel Gaza Palestinians | 2.4 | |
| India North Delhi | 2.2 | |
| Senegal Niokholo Mandenka | 1.6 | |
| Mbenzele Pygmy (C. Afr. Rep.) | 1.5 | |
| Iran Baloch | 1.5 | |
| Pakistan Baloch | 1.5 | |
| Sudanese | 1.5 | |
| Tunisia | 1.5 | |
| Pakistan Brahui | 1.4 | |
| Cameroon Bamileke | 1.3 | |
| Oman | 1.3 | |
| Sudanese | 1.3 | |
| Tunisia Tunis | 1.1 | |
| Zimbabwe Harare Shona | 1.1 | |
| Cameroon Bakola Pygmy | 1.0 | |
| Pakistan Pathan | 1.0 | |
| Portugal Centre | 1.0 | |
| Saudi Arabia Guraiat and Hail | 1.0 | |
| Morocco Casablanca | 0.9 | |
| Senegal Dakar | 0.9 | |
| Uganda Kampala | 0.9 | |
| Cape Verde Southeastern Islands | 0.8 | |
| Guinea Bissau | 0.8 | |
| United Arab Emerates | 0.8 | |
| Morocco Nador Metalsa Class I | 0.7 | |
| Pakistan Karachi Parsi | 0.6 | |
| Spain Majorca | 0.6 | |
| China Yunnan Han pop2 | 0.5 | |
| England Newcastle | 0.5 | |
| Israel Arab Druse | 0.5 | |
| Israel Jews | 0.5 | |
| Italy Rome | 0.5 | |
| Guadalajara Mestizos (2) (Mexico) | 0.5 | |
| Morocco | 0.5 | |
| Pakistan Sindhi | 0.5 | |
| Senegal Niokholo Mandenka | 0.5 | |
| Singapore Riau Malay | 0.5 |