HLA-B18
Encyclopedia
| Alleles | B*1801 | |
| Alleles | B*1802 | |
| Alleles | B*1803 | |
| Structure (See HLA-B HLA-B HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex... ) |
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| Symbol(s) Human Genome Organisation The Human Genome Organisation is an organization involved in the Human Genome Project, a project about mapping the human genome. HUGO was established in 1989 as an international organization, primarily to foster collaboration between genome scientists around the world... |
HLA-B | |
| EBI-HLA European Bioinformatics Institute The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory... |
B*1801 | |
| EBI-HLA European Bioinformatics Institute The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory... |
B*1802 | |
| EBI-HLA European Bioinformatics Institute The European Bioinformatics Institute is a centre for research and services in bioinformatics, and is part of European Molecular Biology Laboratory... |
B*1803 | |
| Locus Locus (genetics) In the fields of genetics and genetic computation, a locus is the specific location of a gene or DNA sequence on a chromosome. A variant of the DNA sequence at a given locus is called an allele. The ordered list of loci known for a particular genome is called a genetic map... |
chr.6 Chromosome 6 (human) Chromosome 6 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 6 spans more than 170 million base pairs and represents between 5.5 and 6% of the total DNA in cells... 6p21.31 |
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HLA-B18 (B18) is an HLA
Human leukocyte antigen
The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...
-B
HLA-B
HLA-B is a human gene that provides instructions for making a protein that plays a critical role in the immune system. HLA-B is part of a family of genes called the human leukocyte antigen complex...
serotype
Serotype
Serotype or serovar refers to distinct variations within a subspecies of bacteria or viruses. These microorganisms, viruses, or cells are classified together based on their cell surface antigens...
. The serotype identifies the more common HLA-B*18 gene products. (For terminology help see: HLA-serotype tutorial) B*1801, the most common allele is at highest frequencies in Northern Italy and the Balkans, a peak frequency distribution it shares with B*3501
HLA-B35
HLA-B35 is an HLA-B serotype. The serotype identifies the more common HLA-B*35 gene products.B35 is one of the largest B serotype groups, it currently has 97 known nucleotide variants and 86 polypeptide isoforms. -Serotype:...
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Serotype
| B*18 | B18 | Sample | |
| allele | % | % | size (N) |
| 1801 | 96 | 1641 | |
| 1802 | 90 | 31 | |
| 1803 | 83 | 29 |
Allele frequencies
| freq | ||
| ref. | Population | (%) |
| Italy North pop 1 | 16.7 | |
| Croatia | 11.3 | |
| Georgia Svaneti Svans | 11.3 | |
| Romanian | 11.3 | |
| Portugal South | 11.2 | |
| Singapore Riau Malay | 9.9 | |
| Bulgaria | 9.1 | |
| Israel Arab Druse | 8.5 | |
| Azores Central Islands | 8.0 | |
| Portugal Centre | 8.0 | |
| Finland | 7.8 | |
| Azores Santa Maria and Sao Miguel | 7.7 | |
| Czech Republic | 7.5 | |
| India Jalpaiguri Toto | 7.5 | |
| Iran Baloch | 7.1 | |
| Philippines Ivatan | 7.0 | |
| Thailand | 6.7 | |
| Tunisia | 6.7 | |
| Portugal North | 6.5 | |
| Zimbabwe Harare Shona | 6.4 | |
| Madeira | 6.2 | |
| Mexico Mestizos | 6.1 | |
| Kenya | 5.9 | |
| Belgium | 5.1 | |
| Morocco Nador Metalsa Class I | 5.1 | |
| Singapore Javanese Indonesians | 5.1 | |
| Israel Ashkenazi and Non Ashkenazi Jews | 5.0 | |
| Uganda Kampala | 5.0 | |
| Kenya Nandi | 4.8 | |
| Oman | 4.7 | |
| Georgia Tibilisi Georgians | 4.6 | |
| Bulgaria Gipsy | 4.5 | |
| France South East | 4.3 | |
| Kenya Luo | 4.3 | |
| Ireland South | 4.2 | |
| Russia Arkhangelsk Pomors | 4.0 | |
| Azores Terceira Island | 3.9 | |
| Guinea Bissau | 3.8 | |
| India New Delhi | 3.8 | |
| Spain Eastern Andalusia Gipsy | 3.5 | |
| Australia New South Wales | 3.4 | |
| Georgia Tibilisi Kurds | 3.4 | |
| Zambia Lusaka | 3.4 | |
| Cameroon Yaounde | 2.7 | |
| Senegal Niokholo Mandenka | 2.7 | |
| Cameroon Beti | 2.3 | |
| Ivory Coast Akan Adiopodoume | 2.3 | |
| Sudanese | 2.3 | |
| Saudi Arabia Guraiat and Hail | 2.2 | |
| South Africian Natal Zulu | 2.0 | |
| Thailand | 2.0 | |
| India Mumbai Marathas | 1.9 | |
| New Caledonia | 1.9 | |
| Papua New Guinea Wanigela | 1.5 | |
| Cameroon Bamileke | 1.3 |