HLA-A69
Encyclopedia
Distribution
| freq | ||
| ref. | Population | (%) |
| Palestinian (Gaza) | 4.8 | |
| North Isl. (Cape Verde) | 4.0 | |
| Druse-Arab (Israel) | 3.0 | |
| South Isl. (Cape Verde) | 2.4 | |
| Mossi (Burkino Faso) | 1.9 | |
| Bulgaria | 1.8 | |
| Jew (Israel) | 1.2 | |
| Tunis (Tunisia) | 1.1 | |
| Bergamo (Italy) | 1.1 | |
| N. Delhi (India) | 1.1 | |
| Amman (Jordon) | 1.0 | |
| Sardinia (Italy) | 1.0 | |
| Central Portugal | 1.0 | |
| Shanghai (China) | 0.7 | |
| Girona (Catalon, Spain) | 0.6 | |
| Baloch (Iran) | 0.6 | |
| Greece | 0.6 | |
| Czech | 0.5 | |
| SE France | 0.4 | |
| Kampala (Uganda) | 0.3 | |
| N. Greece | 0.3 | |
| Romania | 0.3 | |
| Sudanese | 0.25 | |
| U. Arab Emerates | 0.25 | |
| Japan | 0.0 | |
| Croatia | 0.0 | |
| N. Ireland | 0.0 | |
| Zambia | 0.0 | |
| Luo (Kenya) | 0.0 | |
| Nandi (Kenya) | 0.0 | |
| Bandiagara (Mali) | 0.0 |
Distribution of A69 places nodal center in the Levant
Levant
The Levant or ) is the geographic region and culture zone of the "eastern Mediterranean littoral between Anatolia and Egypt" . The Levant includes most of modern Lebanon, Syria, Jordan, Israel, the Palestinian territories, and sometimes parts of Turkey and Iraq, and corresponds roughly to the...
, but high levels in West Africa
West Africa
West Africa or Western Africa is the westernmost region of the African continent. Geopolitically, the UN definition of Western Africa includes the following 16 countries and an area of approximately 5 million square km:-Flags of West Africa:...
. The model of human genetic origin places first migrations from Eastern Africa. However in many east African populations the frequency of A69 is zero. A more consistent model of A69 distribution is either a subsequent migration from West Africa, supported by A36
HLA-A36
-Distribution:A36 is largely limited to Africa. Outside of Africa more than half of the populations have no A36 and the majority that do, have only trace levels. The exception is in Central/East Central Asia. This appears not to be coincidental...
and HLA DR3-DQ2
HLA DR3-DQ2
HLA DR3-DQ2 is double serotype that specifically recognizes cells from individuals who carry a multigene HLA DR, DQ haplotype.Certain HLA DR and DQ genes have known involvementin autoimmune diseases. DR3-DQ2, a multigene...
. The higher levels in the Gaza
Gaza
Gaza , also referred to as Gaza City, is a Palestinian city in the Gaza Strip, with a population of about 450,000, making it the largest city in the Palestinian territories.Inhabited since at least the 15th century BC,...
Palestinians supports this hypothesis.