Distribution

HLA A36 frequencies

		freq
ref.	Population	(%)
	Kenya	6.6
	N. African (non-caucasian)	4.5
	Mossi(Burkino Faso)	3.8
	Beti(Cameroon)	3.7
	Mongolian	3.1
	Lusaka(Zambia)	3.1
	Harare Shona (Zimbabwe)	2.9
	Uygars(China)	2.6
	Bamileke(Cameroon)	2.6
	Amman(Jordon)	2.4
	Fulani	2.0
	Sweden	1.6
	Tswana (S. Africa)	1.2
	Kampala (Uganda)	1.2
	Spain	0.9
	Bubi(Eq. Guinea)	0.5
	!kung (San)	0.0
	Berber(Morroco)	0.0

A36 is largely limited to Africa. Outside of Africa more than half of the populations have no A36 and the majority that do, have only trace levels. The exception is in Central/East Central Asia. This appears not to be coincidental. HLA DR3-DQ2

HLA DR3-DQ2

HLA DR3-DQ2 is double serotype that specifically recognizes cells from individuals who carry a multigene HLA DR, DQ haplotype.Certain HLA DR and DQ genes have known involvementin autoimmune diseases. DR3-DQ2, a multigene...

linkage and frequency indicates a strong possibility of a recent migration from either North or West Africa in which the DR3-DQ2 (notably DRB1*0302) and A*33-B*58 haplotypes were carried into and redistributed from Central Asia into the surrounding populations.