HLA-A28
Encyclopedia
HLA-A28 is a broad antigen HLA
-A
serotype
that recognized the A68
and A69
serotypes. These haplotypes are most common in the middle eastern region and NE Africa but can be found along central Asia to eastern siberia and within the New World.
|+ Subpages for A28 serotypes
|-
| Split antigen serotypes
of A28
|-
| HLA-A68
|-
| HLA-A69
>
Human leukocyte antigen
The human leukocyte antigen system is the name of the major histocompatibility complex in humans. The super locus contains a large number of genes related to immune system function in humans. This group of genes resides on chromosome 6, and encodes cell-surface antigen-presenting proteins and...
-A
HLA-A
HLA-A are a group of human leukocyte antigens that are encoded by the HLA-A locus on human chromosome 6p. The HLA genes constitute a large subset of the Major histocompatibility complex of humans. HLA-A is a component of certain MHC class I cell surface receptor isoforms that resides on the...
serotype
Serotype
Serotype or serovar refers to distinct variations within a subspecies of bacteria or viruses. These microorganisms, viruses, or cells are classified together based on their cell surface antigens...
that recognized the A68
HLA-A68
-By allele:A*68 is associated with higher viral load in HIV. A68 may be protectiveagainst symptomatic heart disease in Chaga's cardiomyopathy.-Allele freqeuncies:A68 can be subdivided into 3 alleles, *6801, *6802, *6803...
and A69
HLA-A69
-Distribution:Distribution of A69 places nodal center in the Levant, but high levels in West Africa. The model of human genetic origin places first migrations from Eastern Africa. However in many east African populations the frequency of A69 is zero. A more consistent model of A69 distribution is...
serotypes. These haplotypes are most common in the middle eastern region and NE Africa but can be found along central Asia to eastern siberia and within the New World.
|-
| Split antigen serotypes
of A28
|-
| HLA-A68
HLA-A68
-By allele:A*68 is associated with higher viral load in HIV. A68 may be protectiveagainst symptomatic heart disease in Chaga's cardiomyopathy.-Allele freqeuncies:A68 can be subdivided into 3 alleles, *6801, *6802, *6803...
|-
| HLA-A69
HLA-A69
-Distribution:Distribution of A69 places nodal center in the Levant, but high levels in West Africa. The model of human genetic origin places first migrations from Eastern Africa. However in many east African populations the frequency of A69 is zero. A more consistent model of A69 distribution is...
>