Gero Miesenböck is Waynflete Professor

Waynflete Professorships

The Waynflete Professorships are four professorial fellowships at the University of Oxford endowed by Magdalen College and named in honour of the college founder William of Waynflete, who had a great interest in science...

  of Physiology

Physiology

Physiology is the science of the function of living systems. This includes how organisms, organ systems, organs, cells, and bio-molecules carry out the chemical or physical functions that exist in a living system. The highest honor awarded in physiology is the Nobel Prize in Physiology or...

 at the University of Oxford

University of Oxford

The University of Oxford is a university located in Oxford, United Kingdom. It is the second-oldest surviving university in the world and the oldest in the English-speaking world. Although its exact date of foundation is unclear, there is evidence of teaching as far back as 1096...

 and a fellow of Magdalen College

Magdalen College, Oxford

Magdalen College is one of the constituent colleges of the University of Oxford in England. As of 2006 the college had an estimated financial endowment of £153 million. Magdalen is currently top of the Norrington Table after over half of its 2010 finalists received first-class degrees, a record...

. A native of Austria

Austria

Austria , officially the Republic of Austria , is a landlocked country of roughly 8.4 million people in Central Europe. It is bordered by the Czech Republic and Germany to the north, Slovakia and Hungary to the east, Slovenia and Italy to the south, and Switzerland and Liechtenstein to the...

, he received his M.D. from the University of Innsbruck and undertook postdoctoral training with James Rothman

James Rothman

James E. Rothman is the Fergus F. Wallace Professor of Biomedical Sciences at Yale University and at Yale University Medical School. He has received many honors, including the Louisa Gross Horwitz Prize from Columbia University and the Albert Lasker Award for Basic Medical Research both in 2002...

. Before coming to Oxford, he held faculty appointments at Memorial Sloan-Kettering Cancer Center

Memorial Sloan-Kettering Cancer Center

Memorial Sloan–Kettering Cancer Center is a cancer treatment and research institution founded in 1884 as the New York Cancer Hospital...

 and Yale University

Yale University

Yale University is a private, Ivy League university located in New Haven, Connecticut, United States. Founded in 1701 in the Colony of Connecticut, the university is the third-oldest institution of higher education in the United States...

.

Miesenböck is the founder of the emerging field of optogenetics

Optogenetics

Optogenetics is the combination of genetic and optical methods to control specific events in targeted cells of living tissue, even within freely moving mammals and other animals, with the temporal precision needed to keep pace with functioning intact biological systems.In 2010, optogenetics was...

. He has developed genetic strategies for visualizing and controlling nerve cells

Neuron

A neuron is an electrically excitable cell that processes and transmits information by electrical and chemical signaling. Chemical signaling occurs via synapses, specialized connections with other cells. Neurons connect to each other to form networks. Neurons are the core components of the nervous...

 with light. He has invented several methods, including genetically targeted photostimulation

Photostimulation

Photostimulation is the use of light to artificially activate biological compounds, cells, or even whole organisms. Photostimulation can be used to noninvasively probe the causal relationships between different biological processes, using only light...

 of neurons and optical imaging

Optical imaging

Optical imaging is an imaging technique.Optics usually describes the behavior of visible, ultraviolet, and infrared light used in imaging.Because light is an electromagnetic wave, similar phenomena occur in X-rays, microwaves, radio waves. Chemical imaging or molecular imaging involves inference...

 of neurotransmission

Neurotransmission

Neurotransmission , also called synaptic transmission, is the process by which signaling molecules called neurotransmitters are released by a neuron , and bind to and activate the receptors of another neuron...

 with synapto-pHluorin

Synapto-pHluorin

Synapto-pHluorin is a genetically encoded optical indicator of vesicle release and recycling. It is used in neuroscience to study transmitter release. It consists of a pH-sensitive form of green fluorescent protein fused to the luminal side of a vesicle-associated membrane protein . At the acidic...

, a derivative of the green fluorescent protein

Green fluorescent protein

The green fluorescent protein is a protein composed of 238 amino acid residues that exhibits bright green fluorescence when exposed to blue light. Although many other marine organisms have similar green fluorescent proteins, GFP traditionally refers to the protein first isolated from the...

.

Miesenböck’s research on optogenetics

Optogenetics

Optogenetics is the combination of genetic and optical methods to control specific events in targeted cells of living tissue, even within freely moving mammals and other animals, with the temporal precision needed to keep pace with functioning intact biological systems.In 2010, optogenetics was...

 and the nervous system

Neuroscience

Neuroscience is the scientific study of the nervous system. Traditionally, neuroscience has been seen as a branch of biology. However, it is currently an interdisciplinary science that collaborates with other fields such as chemistry, computer science, engineering, linguistics, mathematics,...

 of the fruit fly

Drosophila melanogaster

Drosophila melanogaster is a species of Diptera, or the order of flies, in the family Drosophilidae. The species is known generally as the common fruit fly or vinegar fly. Starting from Charles W...

 details the structure and function of neural circuits

Biological neural network

In neuroscience, a biological neural network describes a population of physically interconnected neurons or a group of disparate neurons whose inputs or signalling targets define a recognizable circuit. Communication between neurons often involves an electrochemical process...

 responsible for sensory processing

Sensory system

A sensory system is a part of the nervous system responsible for processing sensory information. A sensory system consists of sensory receptors, neural pathways, and parts of the brain involved in sensory perception. Commonly recognized sensory systems are those for vision, hearing, somatic...

, action selection

Action selection

Action selection is a way of characterizing the most basic problem of intelligent systems: what to do next. In artificial intelligence and computational cognitive science, "the action selection problem" is typically associated with intelligent agents and animats—artificial systems that exhibit...

, and motor pattern generation.